Varietal Counting Of Nucleic Acids For Obtaining Genomic Copy Number Information

Patent No. EP2630263 (titled "Varietal Counting Of Nucleic Acids For Obtaining Genomic Copy Number Information") was filed by Cold Spring Harbor Laboratory on Oct 21, 2011. The application was issued on Nov 10, 2021.

Patent Summary

A method for obtaining genomic copy number information from single cells without amplification distortion, comprising tagging genomic DNA with unique identifiers, sequencing the tagged DNA, and counting the number of unique identifiers at each genomic location to determine copy number. The method enables accurate copy number analysis from single cells by avoiding the amplification biases inherent in traditional whole-genome amplification methods.

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JAMES POOLEJan 25, 2019CARPMAELS & RANSFORD

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EP2630263

COLD SPRING HARBOR LABORATORY
Application Number
EP11835243A
Filing Date
Oct 21, 2011
Status
Patent Maintained As Amended
Oct 8, 2021
Publication Date
Nov 10, 2021