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Detecting And Treating Dementia

Patent No. EP2687223 (titled "Detecting And Treating Dementia") was filed by Mayo Foundation FOR Medical Education And Research on May 30, 2007. The application was issued on Nov 20, 2024.

Methods and materials for detecting and treating frontotemporal dementia (FTD) through progranulin (PGRN) gene analysis and therapy. The methods involve identifying mutations in the PGRN gene that are associated with FTD, and using nucleic acid encoding a PGRN polypeptide to treat the disease. The therapy can involve administering a PGRN polypeptide or nucleic acid to increase PGRN levels in the brain, thereby slowing or halting disease progression.

Patent Family

Patent Oppositions

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

Company	Opposition Date	Representative
JAMES POOLE	Apr 12, 2018	CARPMAELS & RANSFORD

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

Date
Description

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Oct 24, 2024
Decision to maintain the European patent in amended form
Oct 24, 2024
Decision to maintain the European patent in amended form
Oct 11, 2024
(Electronic) Receipt
Oct 11, 2024
Filing of the translation of the amended claims
Oct 11, 2024
French translation of claims
Oct 11, 2024
German translation of the claims
Oct 11, 2024
Letter accompanying subsequently filed items
Aug 22, 2024
Communication of bibliographic data
Aug 22, 2024
Communication to opponent concerning maintenance
Aug 22, 2024
Communication with request to file translations
Aug 19, 2024
Maintenance of the patent with the documents specified in the final decision
Jul 18, 2024
Maintenance of the patent with the documents specified in the final decision
Apr 18, 2024
Brief communication - Opposition proceedings
Apr 18, 2024
Brief communication - Opposition proceedings
Apr 18, 2024
Decision of the Opposition Division and instruction
Apr 18, 2024
Druckexemplar in opposition procedure
Apr 18, 2024
Grounds for the decision (Annex) - opposition
Apr 18, 2024
Interlocutory decision in opposition proceedings
Apr 18, 2024
Interlocutory decision in opposition proceedings
Apr 18, 2024
Means of redress
Jan 15, 2024
Communication of the registration of a transfer or change of name and/or address
Jan 8, 2024
Annexes in respect of a client data request
Jan 8, 2024
Letter accompanying subsequently filed items
Jan 8, 2024
Submission concerning change of applicant's address
Nov 16, 2023
Brief communication - Opposition proceedings
Nov 13, 2023
(Electronic) Receipt
Nov 13, 2023
Letter accompanying subsequently filed items
Nov 13, 2023
Reply to an examination report in opposition proceedings
Nov 9, 2023
Annex to the communication - opposition
Nov 9, 2023
Brief communication - Opposition proceedings
Nov 9, 2023
Brief communication - Opposition proceedings
Nov 9, 2023
Communication inviting the parties to file observations
Nov 9, 2023
Communication inviting the parties to file observations
Jun 22, 2023
Brief communication - Opposition proceedings
Jun 19, 2023
(Electronic) Receipt
Jun 19, 2023
Amended description with annotations
Jun 19, 2023
Clean copy of description pages in the opposition procedure
Jun 19, 2023
Letter accompanying subsequently filed items
Jun 19, 2023
Reply to an examination report in opposition proceedings
May 22, 2023
Annex to the communication - opposition
May 22, 2023
Brief communication - Opposition proceedings
May 22, 2023
Brief communication - Opposition proceedings
May 22, 2023
Communication inviting the parties to file observations
May 22, 2023
Communication inviting the parties to file observations
Jan 20, 2023
Decision of the Board of Appeal
Jan 20, 2023
F3032 Notification(s) of the decision
Jan 20, 2023
F3032 Notification(s) of the decision
Oct 13, 2022
F3013 Oral Proceedings: Forwarding minutes
Oct 13, 2022
F3013 Oral Proceedings: Forwarding minutes
Oct 13, 2022
F3317 Oral Proceedings: Minutes (Appellant: Proprietor + Opponent)
Aug 3, 2022
F3345 Forwarding of submissions to parties
Aug 1, 2022
F3345 Forwarding of submissions to parties
Jul 29, 2022
(Electronic) Receipt
Jul 29, 2022
Amended claims with annotations
Jul 29, 2022
Auxiliary request during appeals procedure - 04
Jul 29, 2022
Letter accompanying subsequently filed items
Jul 29, 2022
Letter dealing with oral proceedings during the appeal procedure
Jul 29, 2022
Request for interpreters during oral proceedings
Jul 27, 2022
(Electronic) Receipt
Jul 27, 2022
Letter accompanying subsequently filed items
Jul 27, 2022
Request for interpreters during oral proceedings
Jul 12, 2022
F3057 Communication: Change of responsibility of a Board of Appeal
Jul 6, 2022
F3305 Communication of the Board of Appeal (ex parte/ inter partes)
Jun 14, 2022
F3022 Oral proceedings: change of board composition
Jun 10, 2022
Annexes in respect of a client data request
Jun 10, 2022
Annexes in respect of a client data request
Jun 10, 2022
Annexes in respect of a client data request
Jun 10, 2022
Annexes in respect of a client data request
Jun 10, 2022
Document concerning representation
Jun 10, 2022
Letter accompanying subsequently filed items
Jun 9, 2022
F3303.16 Change of composition of the Board (T)
Oct 6, 2021
F3011.1 Oral Proceedings: summons
Oct 6, 2021
F3011.1 Oral Proceedings: summons
Oct 6, 2021
F3350 Communication regarding oral proceedings (art. 15 Rules of Procedure of the Boards of Appeal)
Oct 1, 2021
F3010 Oral proceedings: order for summons
Sep 27, 2021
F3303.16 Change of composition of the Board (T)
Aug 5, 2021
Letter accompanying subsequently filed items
Aug 5, 2021
Request for change of opponent's representative
Jul 2, 2021
F3056 Communication: Change of Board due to the technical nature of the appeal
Jul 2, 2021
F3056 Communication: Change of Board due to the technical nature of the appeal
Jun 30, 2021
Composition of the board (T)
Jun 29, 2021
F3313 Order: change of Board due to the technical aspects of the appeal
Dec 18, 2020
Communication of the registration of a transfer or change of name and/or address
Dec 14, 2020
Submission concerning change of applicant's name
Oct 21, 2020
F3345 Forwarding of submissions to parties
Oct 21, 2020
F3345 Forwarding of submissions to parties
Oct 15, 2020
(Electronic) Receipt
Oct 15, 2020
(Electronic) Receipt
Oct 15, 2020
Letter accompanying subsequently filed items
Oct 15, 2020
Letter accompanying subsequently filed items
Oct 15, 2020
Reply to appeal
Oct 15, 2020
Reply to appeal
Jun 5, 2020
F3344 Setting time limit for reply/ file observations to appeal (inter partes)
Jun 5, 2020
F3344 Setting time limit for reply/ file observations to appeal (inter partes)
Jun 2, 2020
(Electronic) Receipt
Jun 2, 2020
Amended claims with annotations
Jun 2, 2020
Amended claims with annotations
Jun 2, 2020
Amended claims with annotations
Jun 2, 2020
Annexes (other than cited documents) regarding appeal procedure
Jun 2, 2020
Annexes (other than cited documents) regarding appeal procedure
Jun 2, 2020
Cited document during appeal procedure
Jun 2, 2020
Cited document during appeal procedure
Jun 2, 2020
Cited document during appeal procedure
Jun 2, 2020
Cited document during appeal procedure
Jun 2, 2020
Cited document during appeal procedure
Jun 2, 2020
Cited document during appeal procedure
Jun 2, 2020
Claims
Jun 2, 2020
Claims
Jun 2, 2020
Letter accompanying subsequently filed items
Jun 2, 2020
Statement of grounds of appeal
Apr 9, 2020
(Electronic) Receipt
Apr 9, 2020
Letter accompanying subsequently filed items
Apr 9, 2020
Statement of grounds of appeal
Feb 14, 2020
F3204 Communication of the file number to the parties
Feb 14, 2020
F3204 Communication of the file number to the parties
Feb 14, 2020
F3204 Communication of the file number to the parties
Feb 14, 2020
F3204 Communication of the file number to the parties
Feb 10, 2020
(Electronic) Receipt
Feb 10, 2020
(Electronic) Receipt
Feb 10, 2020
Letter accompanying subsequently filed items
Feb 10, 2020
Letter accompanying subsequently filed items
Feb 10, 2020
Notice of appeal
Feb 10, 2020
Notice of appeal
Feb 7, 2020
(Electronic) Receipt
Feb 7, 2020
Letter accompanying subsequently filed items
Feb 7, 2020
Notice of appeal
Dec 6, 2019
Advice of delivery
Dec 2, 2019
Advice of delivery
Nov 29, 2019
Acknowledgement of a document
Nov 29, 2019
Acknowledgement of a document
Nov 29, 2019
Annex to the communication - opposition
Nov 29, 2019
Decision of the Opposition Division and instruction
Nov 29, 2019
Grounds for the decision (Annex) - opposition
Nov 29, 2019
Interlocutory decision in opposition proceedings
Nov 29, 2019
Internal form - Opposition/addressees
Nov 29, 2019
Internal form - Opposition/addressees
Nov 29, 2019
Means of redress
Nov 29, 2019
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Nov 29, 2019
Minutes of the oral proceedings (Opposition Division) - conclusion of the proceedings
Nov 29, 2019
Minutes of the oral proceedings (Opposition Division) - introduction of the parties
Nov 29, 2019
OPPODREX with handwritten amendments
Nov 29, 2019
Provision of a copy of the minutes - opposition procedure
Nov 29, 2019
Scanned annex to a communication - opposition procedure
Nov 29, 2019
Scanned annex to a communication - opposition procedure
Nov 29, 2019
Scanned annex to a communication - opposition procedure
Nov 29, 2019
Scanned annex to a communication - opposition procedure
Nov 29, 2019
Scanned annex to a communication - opposition procedure
Sep 24, 2019
Information about the result of oral proceedings
Sep 18, 2019
Acknowledgement of receipt of third party observations
Sep 18, 2019
Brief communication - Opposition proceedings
Sep 18, 2019
Transmittal of third party observations to applicant
Sep 13, 2019
(Electronic) Receipt
Sep 13, 2019
Citation filed by a third party
Sep 13, 2019
Letter accompanying subsequently filed items
Sep 13, 2019
Observations by third parties
Sep 13, 2019
Patent document filed by a Third party
Aug 1, 2019
Brief communication - Opposition proceedings
Aug 1, 2019
Brief communication - Opposition proceedings
Jul 31, 2019
Brief communication - Opposition proceedings
Jul 24, 2019
(Electronic) Receipt
Jul 24, 2019
(Electronic) Receipt
Jul 24, 2019
Amended claims with annotations
Jul 24, 2019
Amended claims with annotations
Jul 24, 2019
Amended claims with annotations
Jul 24, 2019
Amended claims with annotations
Jul 24, 2019
Claims
Jul 24, 2019
Claims
Jul 24, 2019
Claims
Jul 24, 2019
Claims
Jul 24, 2019
Letter accompanying subsequently filed items
Jul 24, 2019
Letter accompanying subsequently filed items
Jul 24, 2019
Non-patent literature cited during the opposition procedure
Jul 24, 2019
Non-patent literature cited during the opposition procedure
Jul 24, 2019
Non-patent literature cited during the opposition procedure
Jul 24, 2019
Non-patent literature cited during the opposition procedure
Jul 24, 2019
Non-patent literature cited during the opposition procedure
Jul 24, 2019
Non-patent literature cited during the opposition procedure
Jul 24, 2019
Written submission in preparation to/during oral proceedings
Jul 24, 2019
Written submission in preparation to/during oral proceedings
Jul 23, 2019
(Electronic) Receipt
Jul 23, 2019
Request for interpreters during oral proceedings
Jul 3, 2019
Brief communication - Opposition proceedings
Jun 28, 2019
(Electronic) Receipt
Jun 28, 2019
Letter accompanying subsequently filed items
Jun 28, 2019
Request for interpreters during oral proceedings
Feb 18, 2019
Advice of delivery
Jan 28, 2019
Advice of delivery
Jan 28, 2019
Advice of delivery
Jan 22, 2019
Advice of delivery
Jan 15, 2019
Acknowledgement of a document
Jan 15, 2019
Acknowledgement of a document
Jan 15, 2019
Annex to the communication - opposition
Jan 15, 2019
Information about the result of oral proceedings
Jan 15, 2019
Information concerning oral proceedings
Jan 15, 2019
Summons to attend oral proceedings
Jan 15, 2019
Summons to attend oral proceedings
Jan 4, 2019
Brief communication - Opposition proceedings
Jan 4, 2019
Brief communication - Opposition proceedings
Dec 20, 2018
(Electronic) Receipt
Dec 20, 2018
Enquiry as to the processing of the file
Dec 20, 2018
Letter accompanying subsequently filed items
Dec 17, 2018
Brief communication - Opposition proceedings
Dec 12, 2018
(Electronic) Receipt
Dec 12, 2018
Citation in opposition procedure
Dec 12, 2018
Citation in opposition procedure
Dec 12, 2018
Citation in opposition procedure
Dec 12, 2018
Citation in opposition procedure
Dec 12, 2018
Letter accompanying subsequently filed items
Dec 12, 2018
Letter regarding the opposition procedure (no time limit)
Dec 12, 2018
Non-patent literature cited during the opposition procedure
Sep 17, 2018
Brief communication - Opposition proceedings
Sep 11, 2018
(Electronic) Receipt
Sep 11, 2018
(Electronic) Receipt
Sep 11, 2018
Amended claims with annotations
Sep 11, 2018
Amended claims with annotations
Sep 11, 2018
Amended claims with annotations
Sep 11, 2018
Amended claims with annotations
Sep 11, 2018
Amended claims with annotations
Sep 11, 2018
Citation in opposition procedure
Sep 11, 2018
Citation in opposition procedure
Sep 11, 2018
Citation in opposition procedure
Sep 11, 2018
Citation in opposition procedure
Sep 11, 2018
Citation in opposition procedure
Sep 11, 2018
Citation in opposition procedure
Sep 11, 2018
Claims
Sep 11, 2018
Claims
Sep 11, 2018
Claims
Sep 11, 2018
Claims
Sep 11, 2018
Claims
Sep 11, 2018
Letter accompanying subsequently filed items
Sep 11, 2018
Letter accompanying subsequently filed items
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Non-patent literature cited during the opposition procedure
Sep 11, 2018
Reply of the patent proprietor to the notice(s) of opposition
May 2, 2018
Communication of a notice of opposition and request to file observations
May 2, 2018
Notice of further oppositions to opponent(s)
Apr 18, 2018
Communication of a notice of opposition - first information to patent proprietor
Apr 12, 2018
(Electronic) Receipt
Apr 12, 2018
Citation in opposition procedure
Apr 12, 2018
Non-patent literature cited during the opposition procedure
Apr 12, 2018
Non-patent literature cited during the opposition procedure
Apr 12, 2018
Non-patent literature cited during the opposition procedure
Apr 12, 2018
Non-patent literature cited during the opposition procedure
Apr 12, 2018
Non-patent literature cited during the opposition procedure
Apr 12, 2018
Non-patent literature cited during the opposition procedure
Apr 12, 2018
Non-patent literature cited during the opposition procedure
Apr 12, 2018
Notice of opposition
Apr 12, 2018
Notice of opposition
Jul 12, 2017
Transmission of the certificate for a European patent pursuant to Rule 74 EPC
Jun 16, 2017
Decision to grant a European patent
Apr 21, 2017
(Electronic) Receipt
Apr 21, 2017
Filing of the translations of the claims
Apr 21, 2017
French translation of claims
Apr 21, 2017
German translation of the claims
Apr 21, 2017
Letter accompanying subsequently filed items
Dec 21, 2016
Bibliographic data of the European patent application
Dec 21, 2016
Communication about intention to grant a European patent
Dec 21, 2016
Intention to grant (signatures)
Dec 21, 2016
Text intended for grant (clean copy)
Dec 21, 2016
Text intended for grant (sequence listing)
Dec 21, 2016
Text intended for grant (version for approval)
Oct 25, 2016
(Electronic) Receipt
Oct 25, 2016
Amended claims with annotations
Oct 25, 2016
Amended description with annotations
Oct 25, 2016
Claims
Oct 25, 2016
Description
Oct 25, 2016
Letter accompanying subsequently filed items
Oct 25, 2016
Reply to communication from the Examining Division
Oct 17, 2016
CDS Clean up - amended data concerning the representative for the applicant
Oct 6, 2016
Submission concerning representation
Oct 5, 2016
Submission concerning representation
Sep 21, 2016
Annex to the communication
Sep 21, 2016
Communication from the Examining Division
Aug 9, 2016
Response to enquiry for communication from the Examining Division
Aug 4, 2016
(Electronic) Receipt
Aug 4, 2016
Enquiry as to when a communication from the Examining Division can be expected
Sep 11, 2015
(Electronic) Receipt
Sep 11, 2015
Letter accompanying subsequently filed items
Sep 11, 2015
Non-patent literature cited during the examination procedure
Sep 11, 2015
Non-patent literature cited during the examination procedure
Sep 11, 2015
Non-patent literature cited during the examination procedure
Sep 11, 2015
Non-patent literature cited during the examination procedure
Sep 11, 2015
Reply to communication from the Examining Division
May 12, 2015
Annex to the communication
May 12, 2015
Communication from the Examining Division
Apr 27, 2015
Examination started
Apr 17, 2015
Response to enquiry for communication from the Examining Division
Apr 13, 2015
Enquiry as to when a communication from the Examining Division can be expected
Oct 16, 2014
Response to enquiry for communication from the Examining Division
Oct 10, 2014
(Electronic) Receipt
Oct 10, 2014
Enquiry as to when a communication from the Examining Division can be expected
Jul 10, 2014
CDS Clean up - amended applicant details
Mar 7, 2014
(Electronic) Receipt
Mar 7, 2014
Amended claims filed after receipt of (European) search report
Mar 7, 2014
Amended claims with annotations
Mar 7, 2014
Amendments received before examination
Mar 7, 2014
Letter accompanying subsequently filed items
Jan 27, 2014
Reminder period for payment of examination fee/designation fee and correction of deficiencies in Written Opinion/amendment
Jan 7, 2014
Notification of forthcoming publication
Dec 20, 2013
Communication regarding the transmission of the European search report
Dec 20, 2013
European search opinion
Dec 20, 2013
European search report
Dec 3, 2013
Search started
Oct 28, 2013
Invitation to indicate correct address of inventor
Oct 28, 2013
Invitation to indicate correct address of inventor
Oct 17, 2013
(Electronic) Receipt
Oct 17, 2013
Converted Sequence Listing
Oct 17, 2013
Letter accompanying subsequently filed items
Oct 17, 2013
Reply to the invitation to remedy deficiencies
Oct 15, 2013
Invitation to indicate correct address of inventor
Oct 11, 2013
Letter which had not been notified
Oct 11, 2013
Letter which had not been notified
Oct 8, 2013
Letter which had not been notified
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Sep 23, 2013
Communication to designated inventor
Aug 14, 2013
Deficiencies in sequence listing
Jul 3, 2013
Abstract
Jul 3, 2013
Acknowledgement of receipt of electronic submission of the request for grant of a European patent
Jul 3, 2013
Claims
Jul 3, 2013
Converted Sequence Listing
Jul 3, 2013
Description
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Designation of inventor
Jul 3, 2013
Drawings
Jul 3, 2013
Letter concerning search matters
Jul 3, 2013
Letter concerning search matters
Jul 3, 2013
Request for grant of a European patent (divisional application)
Mar 4, 2008
Priority document (electronically transmitted)
Mar 4, 2008
Priority document (electronically transmitted)
Mar 4, 2008
Priority document (electronically transmitted)
Mar 4, 2008
Priority document (electronically transmitted)
Mar 4, 2008
Priority document (electronically transmitted)
Mar 4, 2008
Priority document (electronically transmitted)
Mar 4, 2008
Priority document (electronically transmitted)

EP2687223

MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

Application Number: EP13174869A
Filing Date: May 30, 2007
Status: Patent Maintained As Amended; Oct 18, 2024
Publication Date: Nov 20, 2024
External Links: Slate, Register, Google Patents

IP Verse

Detecting And Treating Dementia

Patent Summary

Patent Family

Patent Oppositions

Dossier Documents

EP2687223