Combinations Comprising Brexpiprazole Or A Salt Thereof And A Second Drug For Use In The Treatment Of A Cns Disorder

Patent No. EP2694043 (titled "Combinations Comprising Brexpiprazole Or A Salt Thereof And A Second Drug For Use In The Treatment Of A Cns Disorder") was filed by Otsuka Pharmaceutical on Apr 4, 2012. The application was issued on Nov 1, 2017.

Patent Summary

Combining the drug 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one (Compound (I)) with selective serotonin reuptake inhibitors (SSRIs) or serotonin and norepinephrine reuptake inhibitors (SNRIs) to improve antidepressant efficacy and reduce side effects compared to monotherapy with either drug. The combination targets multiple neurotransmitter systems for more comprehensive antidepressant action. It also enables lower dosing frequency due to sustained release properties of Compound (I).

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Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
GENERICS UKAug 1, 2018ELKINGTON AND FIFE
ALFRED E TIEFENBACHERJul 31, 2018HAMM & WITTKOPP

Dossier Documents

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EP2694043

OTSUKA PHARMACEUTICAL
Application Number
EP12719460A
Filing Date
Apr 4, 2012
Status
Revoked
Feb 21, 2020
Publication Date
Nov 1, 2017