Patent No. EP2752189 (titled "Use Of Anti-Vegf Antibody In Combination With Chemotherapy For Treating Breast Cancer") was filed by F Hoffmann LA Roche on Nov 20, 2009. The application was issued on Oct 26, 2016.

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
| Company | Opposition Date | Representative |
|---|---|---|
| DEHMEL & BETTENHAUSEN | Jul 26, 2017 | RUCKERL |
| HOFFMANN EITLE | Jul 26, 2017 | HOFFMANN EITLE |
| STOLMAR MATTHIAS | Jul 26, 2017 | STOLMAR & PARTNER |
| DR H ULRICH DORRIES | Jul 26, 2017 | GREINER |
| GENERICS UK TRADING MYLAN | Jul 26, 2017 | POHLMAN |
| PFIZER | Jul 26, 2017 | PFIZER |
| ARES TRADING | Jul 25, 2017 | CABINET BEAU DE LOMENIE |
| BOEHRINGER INGELHEIM | Jul 25, 2017 | MOORE |
| GLAS | Jul 24, 2017 | GLAS |
| STADA ARZNEIMITTEL | Jul 24, 2017 | NEUEFEIND |
The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.
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