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Sustained-Release Dosage Forms Of Ruxolitinib

Patent No. EP2919766 (titled "Sustained-Release Dosage Forms Of Ruxolitinib") was filed by Incyte on Nov 14, 2013. The application was issued on May 26, 2021.

Patent Summary

Sustained-release oral dosage form of ruxolitinib, a JAK inhibitor, that reduces the frequency of dosing while maintaining therapeutic efficacy. The dosage form contains ruxolitinib and a sustained-release matrix former like hydroxypropyl methylcellulose. Administering this formulation to humans results in lower peak and trough plasma concentrations of ruxolitinib compared to immediate-release tablets. It also reduces the number of daily doses needed to treat JAK-associated diseases like autoimmunity and myeloproliferative disorders. The sustained-release formulation provides a more consistent and predictable ruxolitinib plasma profile.

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Patent Oppositions (4)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
ALFRED E TIEFENBACHERFeb 28, 2022HAMM&WITTKOPP PATENTANWÄLTE PARTMBB
STADA ARZNEIMITTELFeb 28, 2022HAMM&WITTKOPP PATENTANWÄLTE PARTMBB
MAIWALD PATENT- UND RECHTSANWALTSGESELLSCHAFT MBHFeb 25, 2022MAIWALD PATENT- UND RECHTSANWALTSGESELLSCHAFT MBH
TEVA PHARMACEUTICAL INDUSTRIES LTDFeb 25, 2022D YOUNG

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

  • Date

    Description

EP2919766

INCYTE
Application Number
EP13798840A
Filing Date
Nov 14, 2013
Status
Granted And Under Opposition
Apr 23, 2021
Publication Date
May 26, 2021
External Links
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