IP Verse

(+)-2-[1-(3-Ethoxy-4-Methoxyphenyl)-2-Methylsulfonylethyl]-4-Acetylaminoisoindoline-1,3-Dione: Methods Of Using And Compositions Thereof

Patent No. EP2962690 (titled "(+)-2-[1-(3-Ethoxy-4-Methoxyphenyl)-2-Methylsulfonylethyl]-4-Acetylaminoisoindoline-1,3-Dione: Methods Of Using And Compositions Thereof") was filed by Amgen Europe on Mar 20, 2003. The application was issued on Jan 16, 2019.

Patent Summary

A stereoisomer of a compound called Compound A that is selectively active against TNF-alpha and PDE4 enzymes. The (+) enantiomer of 2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione is described for treating diseases like cancer, inflammatory disorders, and preventing heart failure. It reduces TNF-alpha levels and inhibits PDE4 enzymes. The stereoselective compound provides benefits over the racemic form in terms of potency and reduced side effects.

Patent Family

Patent Family

Patent Oppositions (17)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
ALFRED E TIEFENBACHEROct 16, 2019HAMM & WITTKOPP
CIPLAOct 16, 2019DOMPATENT VON KREISLER SELTING WERNER
CIPLAOct 16, 2019DOMPATENT VON PATENT UND RECHTSANWALTEN
DR REDDYS LABORATORIESOct 16, 2019HAMM & WITTKOPP
GALENICUM HEALTH SLUOct 16, 2019GALENICUM HEALTH SLU
KRKAOct 16, 2019HOEFER & PARTNER
KRKAOct 16, 2019HOEFER & PARTNER PATENTANWALTE MBB
STADA ARZNEIMITTELOct 16, 2019HAMM & WITTKOPP
ZENTIVA KSOct 16, 2019HOFFMANN EITLE
HEXALOct 15, 2019TER MEER STEINMEISTER & PARTNER
QUIMICA SINTETICAOct 15, 2019SCHON
SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETIOct 15, 2019SONNENHAUSER
GENERICS UKOct 11, 2019ELKINGTON AND FIFE
POLPHARMAOct 11, 2019ISARPATENT
ACCORD HEALTHCAREOct 10, 2019HOFFMANN EITLE
HOFFMANN EITLEOct 10, 2019HOFFMANN EITLE
TEVA PHARMACEUTICALSOct 3, 2019D YOUNG

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents

EP2962690

AMGEN EUROPE
Application Number
EP15177140A
Filing Date
Mar 20, 2003
Status
Revoked
Jan 22, 2025
Publication Date
Jan 16, 2019
External Links
Slate, Register , Google Patents