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Methods Of Treating Cancer Using Pd-1 Axis Binding Antagonists And Tigit Inhibitors

Patent No. EP3021869 (titled "Methods Of Treating Cancer Using Pd-1 Axis Binding Antagonists And Tigit Inhibitors") was filed by F Hoffmann LA Roche on Jul 16, 2014. The application was issued on Jul 15, 2020.

Patent Summary

Combining two immunotherapy drugs, an anti-PD-L1 antibody and an anti-TIGIT antibody, to improve cancer treatment by enhancing immune response and function. The dual immunotherapy involves using an anti-PD-L1 antibody to block PD-L1 (programmed cell death ligand 1) interaction with PD-1 (programmed cell death protein 1) on T cells, and an anti-TIGIT antibody to block TIGIT (T cell immunoreceptor with Ig and ITIM domains) interaction with its ligand on dendritic cells. This dual therapy aims to further activate T cells for better cancer immunotherapy by reducing co-inhibitory signals.

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Patent Oppositions (5)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
ARES TRADINGApr 15, 2021MERCK SERONO
JAMES POOLEApr 15, 2021CARPMAELS & RANSFORD
DR H ULRICH DORRIESApr 14, 2021DORRIES
DR H ULRICH DORRIESApr 14, 2021DORRIES, HANS ULRICH , DF-MP DORRIES FRANK-MOLNIA & POHLMAN
DR H ULRICH DRRIESApr 7, 2021DRRIES

Dossier Documents

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EP3021869

F HOFFMANN LA ROCHE
Application Number
EP14750063A
Filing Date
Jul 16, 2014
Status
Revoked
Mar 7, 2025
Publication Date
Jul 15, 2020
External Links
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