IP Verse

Delivery, Engineering And Optimization Of Systems, Methods And Compositions For Sequence Manipulation And Therapeutic Applications

Patent No. EP3031921 (titled "Delivery, Engineering And Optimization Of Systems, Methods And Compositions For Sequence Manipulation And Therapeutic Applications") was filed by Massachusetts Institute OF Technology on Dec 12, 2013. The application was issued on Mar 12, 2025.

Patent Summary

CRISPR genome editing system for therapeutic applications that enables precise and efficient gene editing in eukaryotic cells. The system involves using a chimeric CRISPR RNA (chiRNA) molecule that contains a guide sequence to target a specific location in the genome, and a separate tracr sequence that hybridizes to a separate tracr sequence. This allows more flexible and efficient genome editing by separating the guide and tracr sequences into two separate components. The chiRNA can be delivered as a viral vector for gene therapy applications. The system also includes optimizing the length and sequence of the Cas9 enzyme for improved targeting specificity.

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Patent Oppositions (3)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
GRUND IPG PATENTANWALTE UND SOLICITOR PARTG MBBDec 12, 2025GRUND
VOSSIUS & PARTNERMar 12, 2025VOSSIUS & PARTNER
VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBBMar 12, 2025VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBB

Dossier Documents

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EP3031921

MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Application Number
EP15179123A
Filing Date
Dec 12, 2013
Status
Revoked
Jun 19, 2026
Publication Date
Mar 12, 2025
External Links
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