Patent No. EP3054766 (titled "Methods And Compositions For Peronospora Resistance In Spinach") was filed by Seminis Vegetable Seeds on Oct 8, 2014. The application was issued on Jun 18, 2025.
A *Spinacia oleracea* spinach plant comprises a genome with an introgressed locus from *Spinacia tetrandra* that confers resistance to *Peronospora farinosa* f. sp. *spinaciae* (Pfs), specifically including resistance to at least race 12. The introgressed locus is defined by being flanked in the *S. tetrandra* genome by sequences with at least 99% identity to SEQ ID NOs: 1 and 2. A representative sample of seed containing this locus has been deposited under Accession No. PTA-120533 or PTA-120534. The invention provides broad-spectrum resistance to downy mildew, overcoming the limitations of race-specific resistance typically found in cultivated spinach or *S. turkestanica* and allowing for introgression into desired genomic backgrounds via marker-assisted selection.

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