Methods For Controlling Blood Pharmacokinetics Of Antibodies

Patent No. EP3056568 (titled "Methods For Controlling Blood Pharmacokinetics Of Antibodies") was filed by Chugai Seiyaku Kabushiki Kaisha on Mar 30, 2007. The application was issued on Sep 15, 2021.

Patent Summary

Methods for controlling the blood half-life of antibodies by modifying surface-exposed amino acid residues in the variable regions, without affecting antibody structure or function. The modification involves amino acid substitutions that shift the isoelectric point (pI) of the antibody, enabling control of pharmacokinetics in blood. The methods are applicable to humanized, chimeric, and human antibodies, and can be used to prolong or reduce the half-life of antibodies in blood.

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Patent Family

Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
NOVO NORDISKJun 15, 2022J A KEMP
STRAWMANJun 14, 2022PLASSERAUD

Dossier Documents

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EP3056568

CHUGAI SEIYAKU KABUSHIKI KAISHA
Application Number
EP15196240A
Filing Date
Mar 30, 2007
Status
Granted And Under Opposition
Aug 13, 2021
Publication Date
Sep 15, 2021