IP Verse

Crush-Resistant Tablets Intended For Preventing Accidental Misuse And Unlawful Diversion

Patent No. EP3115041 (titled "Crush-Resistant Tablets Intended For Preventing Accidental Misuse And Unlawful Diversion") was filed by Ethypharm on Mar 1, 2007. The application was issued on Oct 25, 2023.

Patent Summary

Water-insoluble matrix tablets for extended release of abuse-prone active ingredients (e.g., morphine, oxycodone, hydrocodone, hydromorphone, oxymorphone, tramadol, methadone, codeine, and their salts) comprise a compression matrix of microcrystalline cellulose and polyvinyl acetate/polyvinylpyrrolidone (80:20). To prevent drug abuse via crushing, inhalation, or injection, tablets are formulated with a crushing strength ($\text{R}_d$) of at least 4 MPa, preferably $\ge 6$ MPa, calculated as $\text{R}_d = 2\text{F} / (\pi \text{D} \text{h})$, where $\text{F}$ is fracture force (N), $\text{D}$ is diameter (mm), and $\text{h}$ is thickness (mm). These tablets exhibit high crush resistance, near-zero friability, and pH-independent, prolonged release profiles (e.g., $>12$ hours) that remain stable in aqueous and alcoholic media, preventing dose-dumping and extraction.

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Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
G L PHARMAJul 25, 2024SONN PATENTANWALTE
HERTIN UND PARTNER RECHTSJul 25, 2024HERTIN UND PARTNER RECHTS

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

  • Date

    Description

EP3115041

ETHYPHARM
Application Number
EP16183449A
Filing Date
Mar 1, 2007
Status
Granted And Under Opposition
Sep 22, 2023
Publication Date
Oct 25, 2023
External Links
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