Nucleic Acid Vaccines

Patent No. EP3134131 (titled "Nucleic Acid Vaccines") was filed by Moderna on Apr 23, 2015. The application was issued on Dec 22, 2021.

Patent Summary

This nucleic acid vaccine comprises one or more mRNA polynucleotides encoding an antigenic polypeptide derived from Influenza A, Influenza B, or combinations thereof, specifically a hemagglutinin protein or fragment. The mRNA includes at least one chemical modification selected from a specified group, including pseudouridine, N1-methylpseudouridine, and various thio-modified or methylated uridines/cytosines. The polynucleotides are formulated in a lipid nanoparticle (LNP) with a molar ratio of 20-60% cationic lipid, 5-25% non-cationic lipid, 25-55% sterol, and 0.5-15% PEG-modified lipid. The vaccine is designed to induce antigen-specific immune responses (T cell and B cell) for the prophylaxis or treatment of influenza viral infections via intradermal or intramuscular administration.

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Patent Oppositions (5)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
BIONTECHSep 22, 2022WILK
PFIZERSep 22, 2022EDER
SEQIRUS UKSep 21, 2022CARPMAELS & RANSFORD
WITHERS & ROGERSSep 16, 2022TOMBLING
SANOFISep 13, 2022CARPMAELS & RANSFORD

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

  • Date

    Description

EP3134131

MODERNA
Application Number
EP15783606A
Filing Date
Apr 23, 2015
Status
Granted And Under Opposition
Nov 19, 2021
Publication Date
Dec 22, 2021