Coronavirus
Patent No. EP3172319 (titled "Coronavirus") was filed by The Pirbright Institute on Jul 23, 2015. The application was issued on Nov 20, 2019.
Patent Summary
Live attenuated coronavirus vaccine strain for preventing infectious bronchitis in chickens. The vaccine virus has a modified replicase gene that encodes proteins with specific mutations. These mutations reduce the pathogenicity of the virus compared to the wild-type replicase gene. The attenuated virus can replicate in chicken embryos without causing disease, making it suitable for in ovo vaccination. The mutations in the replicase gene are in nsp-14, a protein involved in RNA synthesis. The mutations are Val393Leu in nsp-14.
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Date
Description
EP3172319
- Application Number
- EP15750093A
- Filing Date
- Jul 23, 2015
- Status
- Granted And Under Opposition
- Nov 6, 2020
- Publication Date
- Nov 20, 2019
- External Links
- Slate, Register , Google Patents