IP Verse

Sacubitril-Valsartan Dosage Regimen For Treating Heart Failure

Patent No. EP3294283 (titled "Sacubitril-Valsartan Dosage Regimen For Treating Heart Failure") was filed by Novartis on May 9, 2016. The application was issued on Mar 8, 2023.

Patent Summary

Treatment of heart failure in a human patient that prevents the onset of a disease characterized and / or manifested by atrial enlargement and/or remodeling. The treatment comprises administering to a patient in need thereof a twice-daily target dose of an Angiotensin Receptor Neprilysin inhibitor (ARNi) or of a combination of an Angiotensin Receptor Blocker (ARB) with a Neutral Endopeptidase inhibitor (NEPi) or with a NEPi pro-drug, wherein said target dose is reached after a titration with an initial lower twice-daily dose of said ARNI increasing to the twice daily target dose from 5 to 8 weeks.

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Patent Oppositions (16)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
BULLE DRDec 8, 2023KUTZENBERGER WOLFF & PARTNER
KRKADec 8, 2023HOFFMANN EITLE
ZENTIVADec 8, 2023GREINER
ALFRED E TIEFENBACHERDec 7, 2023HAMM & WITTKOPP
BETAPHARM ARZNEIMITTELDec 7, 2023HAMM & WITTKOPP
GENERICS UKDec 7, 2023ELKINGTON AND FIFE
POLPHARMADec 7, 2023HAMM & WITTKOPP
SANOVEL IIAC SAN VE TICDec 7, 2023KRAUS & LEDERER
SANOVEL IIAC SAN VE TICDec 7, 2023KRAUS & LEDERER PARTGMBB
STRAWMANDec 7, 2023PINSENT MASONS
SYNTHONDec 7, 2023HAMM & WITTKOPP
TEVA PHARMACEUTICALSDec 7, 2023D YOUNG
HOFFMANN EITLEDec 4, 2023HOFFMANN EITLE
DR SCHONNov 30, 2023DR SCHON
CAMULONNov 23, 2023REDDIE & GROSE
EGISOct 9, 2023STOLMAR & PARTNER

Dossier Documents

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EP3294283

NOVARTIS
Application Number
EP16722388A
Filing Date
May 9, 2016
Status
Granted And Under Opposition
Feb 3, 2023
Publication Date
Mar 8, 2023
External Links
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