IP Verse

Dosing Regimen Of Anti-Alpha4Beta7-Antibodies

Patent No. EP3329965 (titled "Dosing Regimen Of Anti-Alpha4Beta7-Antibodies") was filed by Millennium Pharmaceuticals on May 2, 2012. The application was issued on Mar 19, 2025.

Patent Summary

A stable formulation of anti-α4β7 antibodies for therapeutic applications in inflammatory bowel disease, comprising a buffer, stabilizer, and antibody. The formulation achieves enhanced stability through a specific molar ratio of non-reducing sugar to antibody, with a buffer component maintaining optimal pH and buffer capacity. The formulation can be formulated as a dry, lyophilized product or liquid solution, with the molar ratio of non-reducing sugar to antibody exceeding 600:1. The formulation maintains the antibody's conformational integrity while protecting its functional groups from degradation, enabling effective therapeutic delivery.

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Patent Oppositions (7)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
GRAF VON STOSCH PATENTANWALTSGESELLSCHAFTDec 19, 2025LEPTHIEN
STORZDec 19, 2025MICHALSKI HUTTERMANN & PARTNER
STORZDec 19, 2025MICHALSKI HUTTERMANN & PARTNER PATENTANWALTE MBB
ABEL & IMRAYDec 18, 2025ABEL & IMRAY
ADVANZ PHARMA SERVICES UKDec 18, 2025ELKINGTON AND FIFE
FRESENIUS KABI SWISSBIOSIMDec 18, 2025D YOUNG
BRAND MURRAY FULLERDec 17, 2025BRAND MURRAY FULLER

Dossier Documents

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EP3329965

MILLENNIUM PHARMACEUTICALS
Application Number
EP18150968A
Filing Date
May 2, 2012
Status
Granted And Under Opposition
Feb 14, 2025
Publication Date
Mar 19, 2025
External Links
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