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Method For Treating Multiple Sclerosis

Patent No. EP3359572 (titled "Method For Treating Multiple Sclerosis") was filed by F Hoffmann LA Roche on Oct 6, 2016. The application was issued on Nov 27, 2024.

Patent Summary

The invention provides an anti-CD20 antibody, specifically ocrelizumab, for use in a method to improve functional ability in human patients with multiple sclerosis. The method comprises administering an effective amount of ocrelizumab to patients diagnosed with primary progressive multiple sclerosis (PPMS) who exhibit T1 gadolinium staining lesions at baseline. Improvement in functional ability is quantified using the Expanded Disability Status Scale (EDSS) score or the Timed 25-Foot Walk (T-25FW) test. The treatment targets the inflammatory and demyelinating degenerative processes of the central nervous system characteristic of PPMS, a subtype of MS typically marked by gradual progression from onset with rare relapses and remissions.

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Patent Oppositions (6)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
ABEL & IMRAYAug 27, 2025ABEL & IMRAY
ELKINGTON AND FIFEAug 27, 2025ELKINGTON AND FIFE
GRUNECKER PATENT UND RECHTSANWALTE PARTG MBBAug 27, 2025GRUNECKER PATENT
HEXALAug 27, 2025HOFFMANN EITLE
STRAWMANAug 27, 2025HOFFMANN EITLE
POLPHARMA BIOLOGICSAug 26, 2025WICHMANN

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

  • Date

    Description

EP3359572

F HOFFMANN LA ROCHE
Application Number
EP16790464A
Filing Date
Oct 6, 2016
Status
Granted And Under Opposition
Oct 25, 2024
Publication Date
Nov 27, 2024
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