IP Verse

Restoring Function To A Non-Functional Gene Product Via Guided Cas Systems And Methods Of Use

Patent No. EP3365440 (titled "Restoring Function To A Non-Functional Gene Product Via Guided Cas Systems And Methods Of Use") was filed by Pioneer HI Bred on Oct 17, 2016. The application was issued on Sep 14, 2022.

Patent Summary

This method involves the DNA-free, particle-mediated delivery of a ribonucleoprotein (RNP) complex into a plant cell containing a cell wall. The RNP complex, comprising a Cas endonuclease protein and a guide RNA with a polynucleotide sequence complementary to a genomic target site, is applied to a particle delivery matrix containing a microparticle. Once introduced, the RNP complex binds to the target genomic sequence. The technology is utilized for genome editing, including restoring function to non-functional gene products (e.g., correcting frameshift mutations via NHEJ without a modification template) and modifying nucleotide sequences. The system can employ restored functional selectable markers to identify modified cells without introducing recombinant DNA constructs.

Patent Family

Patent Family

Patent Oppositions (3)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
EISENFUHR SPEISERJun 13, 2023EISENFUHR SPEISER
SOLDENWAGNERJun 13, 2023EISENFUHR SPEISER
SYNGENTA CROP PROTECTIONJun 13, 2023HARRISON GODDARD FOOTE

Dossier Documents

The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.

  • Date

    Description

  • Get instant alerts for new documents

EP3365440

PIONEER HI BRED
Application Number
EP16788879A
Filing Date
Oct 17, 2016
Status
Granted And Under Opposition
Aug 12, 2022
Publication Date
Sep 14, 2022
External Links
Slate, Register , Google Patents