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Neoantigen Identification, Manufacture, And Use

Patent No. EP3389630 (titled "Neoantigen Identification, Manufacture, And Use") was filed by Gritstone BIO on Dec 16, 2016. The application was issued on Nov 8, 2023.

Patent Summary

A method for identifying neoantigens that can be presented by tumor cells for cancer immunotherapy. The method employs a novel approach to neoantigen identification that integrates mass spectrometry data with computational models to predict peptide presentation by tumor MHC alleles. The method trains models on peptide sequences from tumor samples and presents them to MHC alleles, generating likelihoods of peptide presentation. These likelihoods are then used to select the most promising neoantigens for vaccine development. The approach addresses the limitations of current methods by incorporating mass spectrometry data and computational models to improve peptide presentation predictions.

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Patent Oppositions (4)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
BIONTECHAug 8, 2024THOMANN
MARGARET DIXONAug 8, 2024MEWBURN ELLIS
STRAWMANAug 8, 2024HGF
INSPICOS PSAug 7, 2024INSPICOS PS

Dossier Documents

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EP3389630

GRITSTONE BIO
Application Number
EP16876766A
Filing Date
Dec 16, 2016
Status
Granted And Under Opposition
Oct 6, 2023
Publication Date
Nov 8, 2023
External Links
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