Patent No. EP3490560 (titled "Methods Of Treating Prostate Cancer") was filed by Janssen Pharmaceutica on Jul 28, 2017. The application was issued on Jan 22, 2025.
Niraparib, a PARP inhibitor, is used to treat prostate cancer in patients with DNA repair anomalies, such as BRCA-1 or BRCA-2 mutations. The treatment is effective in patients with castration-resistant prostate cancer, including those who have failed androgen receptor-targeted therapies. Niraparib's mechanism of action involves inducing DNA damage and inhibiting PARP-mediated repair, leading to tumor cell death. The treatment is administered orally and can be used in combination with androgen deprivation therapy.

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
| Company | Opposition Date | Representative |
|---|---|---|
| HAMM & WITTKOPP | Oct 21, 2025 | HAMM & WITTKOPP |
| TEVA PHARMACEUTICALS | Oct 21, 2025 | VON KAUFFMANN |
| GENERICS UK | Oct 20, 2025 | RUSSELL |
| SANDOZ | Sep 17, 2025 | ELKINGTON AND FIFE |
The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.
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