Patent No. EP3539540 (titled "Pharmaceutical Composition, Methods For Treating And Uses Thereof") was filed by Boehringer Ingelheim on Nov 7, 2011. The application was issued on Dec 18, 2024.
A pharmaceutical composition for preventing, treating, or reducing the risk of hypoglycemia in patients with diabetes, comprising an SGLT2 inhibitor and an insulin, administered in combination or alternation. The composition is particularly effective in patients with type 1 diabetes, where it can reduce the risk of hypoglycemia and improve glycemic control. The SGLT2 inhibitor works by inhibiting glucose reabsorption in the kidneys, while the insulin provides glucose-lowering effects. The combination of the two can prolong the duration of insulin efficacy, reduce the required insulin dose, and prevent or delay the progression of diabetes complications.

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
| Company | Opposition Date | Representative |
|---|---|---|
| DR REDDYS LABORATORIES UK BETAPHARM ARZNEIMITTEL | Sep 18, 2025 | MAIWALD |
| ELEND | Sep 18, 2025 | JOHNSON |
| GENERICS UK | Sep 18, 2025 | TER MEER STEINMEISTER & PARTNER |
| SANDOZ | Sep 18, 2025 | ELKINGTON AND FIFE |
| STADA ARZNEIMITTEL | Sep 18, 2025 | KERNEBECK |
| POLPHARMA | Sep 17, 2025 | ELKINGTON AND FIFE |
| HAMM & WITTKOPP | Sep 16, 2025 | HAMM & WITTKOPP |
| WUESTHOFF & WUESTHOFF | Sep 16, 2025 | SONNENHAUSER |
| CAMULON | Sep 15, 2025 | REDDIE & GROSE |
| TEVA PHARMACEUTICALS | Sep 12, 2025 | KRAUS & LEDERER PARTGMBB |
| BARDEHLE PAGENBERG | Sep 10, 2025 | BARDEHLE PAGENBERG SL |
The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.
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