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Rna-Guided Human Genome Engineering

Patent No. EP3553174 (titled "Rna-Guided Human Genome Engineering") was filed by President And Fellows OF Harvard College on Dec 16, 2013. The application was issued on Apr 30, 2025.

Patent Summary

A CRISPR-Cas9 system for genome editing that enables precise targeting of specific genomic sequences without the need for RNA processing machinery. The system utilizes a novel RNA-guided approach where the RNA is directly expressed and binds to the target DNA, while the Cas9 enzyme performs the actual cleavage. This approach eliminates the need for RNA processing, transcription, and processing of the RNA itself, allowing for efficient and precise genome editing at multiple target sites. The system can be engineered to target specific genomic regions, including exons, and can be adapted for use in eukaryotic cells, including mammalian cells.

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Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
SCHLICHJan 30, 2026SCHLICH
VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBBDec 30, 2025VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBB

Dossier Documents

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EP3553174

PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Application Number
EP19173061A
Filing Date
Dec 16, 2013
Status
Granted And Under Opposition
Mar 28, 2025
Publication Date
Apr 30, 2025
External Links
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