Patent No. EP3621596 (titled "Nucleic Acid Vector Tablets") was filed by Centre National DE LA Recherche Scientifique on May 9, 2018. The application was issued on Feb 23, 2022.
Method for manufacturing tablets containing nucleic acid vectors for oral, vaginal, rectal, sublingual or transmucosal administration. The method involves drying a complex of nucleic acid and lipid particles containing cationic lipids, followed by compression into tablets. The lipid particles can be liposomes or micelles. The drying step can be lyophilization. The tablets provide a convenient oral dosage form for nucleic acids that avoids the limitations of injectable vectors.

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