IP Verse

New Use

Patent No. EP3626270 (titled "New Use") was filed by Novartis on Aug 26, 2014. The application was issued on Oct 11, 2023.

Patent Summary

Angiotensin Receptor Neprilysin Inhibitors (ARNIs) and combined ARBs with NEPi pro-drugs for the prevention or delay of cardiovascular mortality and hospitalization in heart failure patients. The ARNI/ARB combination therapy demonstrates significant mortality reduction in patients with reduced ejection fraction, a key population for heart failure treatment, compared to conventional ACE inhibitors. This dual-action approach combines the RAAS pathway's natural compensatory mechanisms with the NEP's N-terminal dipeptidyl peptidase-IV inhibitor properties, achieving sustained benefits beyond traditional treatments.

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Patent Family

Patent Oppositions (17)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
ELPEN PHARMACEUTICALJul 11, 2024HASELTINE LAKE KEMPNER
GENERICS UKJul 11, 2024ELKINGTON AND FIFE
LANYON OPPOSITIONSJul 11, 2024PINSENT MASONS
ZENTIVA KSJul 11, 2024GREINER
BULLE DRJul 10, 2024KUTZENBERGER WOLFF & PARTNER
CAMULONJul 10, 2024REDDIE & GROSE
DR SCHONJul 10, 2024DR SCHON
POLPHARMAJul 10, 2024HAMM & WITTKOPP
SYNTHONJul 10, 2024HOFFMANN EITLE
TEVA PHARMACEUTICALSJul 10, 2024D YOUNG
WUESTHOFF & WUESTHOFFJul 10, 2024SONNENHAUSER
HOFFMANN EITLEJul 9, 2024HOFFMANN EITLE
EGISJul 8, 2024STOLMAR & PARTNER
HAMM & WITTKOPPJul 5, 2024HAMM & WITTKOPP
HAMM & WITTKOPPJul 5, 2024HAMM & WITTKOPP
BETAPHARM ARZNEIMITTELJul 2, 2024HAMM & WITTKOPP
ALFRED E TIEFENBACHERJun 25, 2024HAMM & WITTKOPP

Dossier Documents

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EP3626270

NOVARTIS
Application Number
EP19202854A
Filing Date
Aug 26, 2014
Status
Granted And Under Opposition
Sep 8, 2023
Publication Date
Oct 11, 2023
External Links
Slate, Register , Google Patents