Mutated Glycoprotein Of Vesicular Stomatitis Virus

Patent No. EP3684786 (titled "Mutated Glycoprotein Of Vesicular Stomatitis Virus") was filed by Centre National DE LA Recherche Scientifique Cnrs on Sep 24, 2018. The application was issued on Aug 14, 2024.

Patent Summary

VSV-G protein that targets cancer cells by blocking LDL receptor binding while keeping membrane fusion. Mutating key amino acids at positions 47 and 354 stops the virus from attaching to normal cells, but the protein still fuses with cell membranes to enter. A peptide tag can be added to redirect the virus to specific tumor markers. This allows oncolytic viruses to enter cancer cells without infecting healthy tissue, enabling precise cancer treatment.

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Patent Oppositions (2)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
BOULT WADE TENNANTMay 14, 2025BOULT WADE TENNANT
DORRIESMay 14, 2025DORRIES

Dossier Documents

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  • Date

    Description

EP3684786

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Application Number
EP18773448A
Filing Date
Sep 24, 2018
Status
Granted And Under Opposition
Jul 12, 2024
Publication Date
Aug 14, 2024