Patent No. EP3689365 (titled "Use Of Long-Acting Glp-1 Peptides") was filed by Novo Nordisk on Jun 21, 2013. The application was issued on Aug 6, 2025.
Improved GLP-1 agonist therapy for type 2 diabetes and obesity, comprising once-weekly administration of semaglutide in doses of 0.4-1.6 mg, which provides superior glycemic control and weight loss compared to daily liraglutide doses. The therapy is characterized by a prolonged half-life, enhanced stability against gastrointestinal enzymes, and improved potency in stimulating GLP-1 receptor activity.

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