Patent No. EP3735972 (titled "Multi-Layer Nicotine-Containing Pharmaceutical Composition") was filed by Modoral Brands on Feb 7, 2013. The application was issued on Nov 19, 2025.
This pharmaceutical composition for oral delivery of a nicotinic compound comprises a core formulation surrounded by one or more continuous layers of different formulations. The core and surrounding layers possess distinct organoleptic properties. The core formulation is specifically provided as a granular powder, and the composition features a nicotinic compound sorbed onto a porous particulate carrier. The multi-layered structure may utilize various formulation types, including lozenge, meltable, chewable, hard coating, or molded (starch or injection) forms, to achieve modified delivery profiles, such as fast or extended release. The composition is intended for therapeutic use, including as a smoking cessation aid or for treating conditions responsive to nicotinic acetylcholinergic receptor stimulation.

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