Patent No. EP4041186 (titled "An Anhydrous Pharmaceutical Composition For Maintenance Treatment Of Psoriasis") was filed by LEO Pharma on Oct 7, 2020. The application was issued on May 22, 2024.
An anhydrous topical pharmaceutical composition for maintaining psoriasis remission by treating psoriasis patients when they are in remission following an initial course of therapy. The composition contains calcipotriol, betamethasone, petrolatum, and a propellant. The patients apply the composition biweekly when they are in remission to prevent relapses and prolong remission duration compared to not using the composition. The biweekly maintenance treatment reduces relapse rate, time to first relapse, and improves remission duration versus no maintenance therapy.

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