Solid State Forms Of Mavacamten And Process For Preparation Thereof
Patent No. EP4097091 (titled "Solid State Forms Of Mavacamten And Process For Preparation Thereof") was filed by Assia Chemical Industries on Jan 28, 2021. The application was issued on Sep 18, 2024.
Patent Summary
Solid-state forms of Mavacamten, including crystalline polymorphs, for the treatment of obstructive hypertrophic cardiomyopathy (oHCM), comprising anhydrous crystalline polymorphs of Mavacamten that exhibit stable crystal structures under various conditions. These crystalline polymorphs, including Form 1 and Form 5, have distinct crystal structures and physical properties like melting point, thermal behaviors, X-ray diffraction patterns, infrared absorption fingerprint, and solid-state (13C) NMR spectra, which enable formulation optimization for pharmaceutical applications.
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Date
Description
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EP4097091
- Application Number
- EP21706793A
- Filing Date
- Jan 28, 2021
- Status
- Granted And Under Opposition
- Aug 15, 2024
- Publication Date
- Sep 18, 2024
- External Links
- Slate, Register , Google Patents