Heart Tissue Model
Patent No. EP4121512 (titled "Heart Tissue Model") was filed by Imba Institut FR Molekulare Biotechnologie on Mar 19, 2021. The application was issued on Aug 21, 2024.
Patent Summary
Heart tissue model generated through directed differentiation of pluripotent stem cells into cardiac cells in a 3D culture system. The model mimics early heart development by forming a continuous cardiomyocyte layer around an inner cavity, with endocardial cells lining the cavity. The model is generated through a combination of natural growth factors and inhibitors, allowing for precise control over cell differentiation and organization. The model exhibits cardiac cell-cell interactions and maintains a functional beating rhythm, making it a valuable tool for studying cardiac development and disease mechanisms.
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Date
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EP4121512
- Application Number
- EP21712188A
- Filing Date
- Mar 19, 2021
- Status
- Granted And Under Opposition
- Jul 19, 2024
- Publication Date
- Aug 21, 2024
- External Links
- Slate, Register , Google Patents