Patent No. EP4175479 (titled "Process For The Preparation Of A Powdery Composition Comprising Bioactive Molecules") was filed by Frieslandcampina Nederland on Jun 30, 2021. The application was issued on Aug 20, 2025.
A process for preparing a powder from a liquid composition containing bioactive molecules, such as those naturally occurring in milk, minimizes denaturation by reducing heat load prior to spray-drying. The process comprises: (a) providing the liquid composition; (b) optionally pre-heating it to $\le$65°C; (c) transporting it via a tower feeding line to the top of a spray-drying tower; (d) raising the temperature to 60-90°C using a direct electric volumetric heater (e.g., ohmic or PEF heating) located within the feeding line near the atomizer, ensuring the liquid moves from the heater to the atomizer in $<$40 seconds; and (e) transporting the composition to the atomizer. This minimizes the duration the composition remains above the bioactive molecules' denaturation temperature.

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