Patent No. EP4188327 (titled "Combination Therapy For Inhalation Administration") was filed by Chemo Research on Jul 30, 2021. The application was issued on May 28, 2025.
A pharmaceutical composition for soft mist inhaler administration comprising a combination of an inhaled corticosteroid (ICS) with a long-acting β2-agonist (LABA) and optionally a long-acting muscarinic antagonist (LAMA) for treating respiratory diseases such as asthma and COPD. The composition is a solution of the active ingredients dissolved in an alcoholic solvent, which provides higher lung deposition compared to other pharmaceutical forms. The formulation is free of propellant, stabilizing agents, and preservatives, and is suitable for use in a soft mist inhaler.

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
| Company | Opposition Date | Representative |
|---|---|---|
| MURGITROYD | Feb 27, 2026 | MURGITROYD |
| SCORPIO | Feb 27, 2026 | SAGITTARIUS |
| BRAND MURRAY FULLER | Feb 26, 2026 | BRAND MURRAY FULLER |
| HIGHTONE MANAGEMENT | Oct 1, 2025 | GILL JENNINGS & EVERY |
The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.
Date
Description
Sep 16, 2026
Sep 16, 2026
Sep 16, 2026
Sep 16, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Sep 11, 2026
Jun 19, 2026
Jun 19, 2026
Jun 19, 2026
Jun 19, 2026
Jun 19, 2026
Jun 11, 2026
Jun 11, 2026
Jun 11, 2026
Jun 11, 2026
Jun 8, 2026
Jun 8, 2026
Jun 8, 2026
Mar 13, 2026
Mar 13, 2026
Mar 13, 2026
Mar 13, 2026
Mar 13, 2026
Mar 6, 2026
Mar 4, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 27, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Feb 26, 2026
Oct 7, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Oct 1, 2025
Jun 11, 2025
May 16, 2025
May 16, 2025
May 16, 2025
May 6, 2025
May 6, 2025
May 2, 2025
Apr 22, 2025
Apr 22, 2025
Apr 22, 2025
Apr 22, 2025
Apr 22, 2025
Mar 10, 2025
Mar 10, 2025
Mar 10, 2025
Mar 10, 2025
Mar 10, 2025
Mar 10, 2025
Oct 22, 2024
Oct 22, 2024
Oct 22, 2024
Oct 22, 2024
Oct 22, 2024
Jul 3, 2024
Jul 3, 2024
Mar 20, 2024
Mar 20, 2024
Mar 20, 2024
Mar 20, 2024
Mar 20, 2024
Feb 14, 2024
Feb 14, 2024
Feb 14, 2024
Jan 18, 2024
Jan 18, 2024
Jan 5, 2024
Nov 17, 2023
Nov 17, 2023
Nov 17, 2023
Nov 17, 2023
Nov 17, 2023
Nov 14, 2023
Nov 14, 2023
Nov 8, 2023
Nov 8, 2023
Nov 8, 2023
Sep 22, 2023
Sep 22, 2023
Sep 18, 2023
Sep 18, 2023
Sep 18, 2023
Sep 18, 2023
Sep 18, 2023
Sep 18, 2023
Sep 18, 2023
Sep 18, 2023
Sep 18, 2023
May 10, 2023
Mar 7, 2023
Feb 28, 2023
Feb 6, 2023
Jan 26, 2023
Jan 26, 2023
Jan 26, 2023
Jan 26, 2023
Dec 9, 2022
Oct 19, 2022
Oct 19, 2022
Oct 19, 2022
Oct 19, 2022
Oct 19, 2022
Oct 19, 2022
Sep 20, 2022
Sep 20, 2022
Sep 20, 2022
Sep 20, 2022
Sep 20, 2022
Sep 20, 2022
Jul 20, 2022
Jul 20, 2022
Jul 20, 2022
Jun 28, 2022
Jun 8, 2022
May 30, 2022
May 30, 2022
May 30, 2022
May 30, 2022
Feb 21, 2022
Feb 3, 2022
Feb 3, 2022
Sep 1, 2021
Sep 1, 2021
Sep 1, 2021
Aug 31, 2021
Aug 31, 2021
Jul 30, 2021
Jul 30, 2021
Jul 30, 2021
Jul 30, 2021
Jul 30, 2021
Jul 30, 2021
Jul 30, 2021
Jul 30, 2021