Patent No. EP4188327 (titled "Combination Therapy For Inhalation Administration") was filed by Chemo Research on Jul 30, 2021. The application was issued on May 28, 2025.
A pharmaceutical composition for soft mist inhaler administration comprising a combination of an inhaled corticosteroid (ICS) with a long-acting β2-agonist (LABA) and optionally a long-acting muscarinic antagonist (LAMA) for treating respiratory diseases such as asthma and COPD. The composition is a solution of the active ingredients dissolved in an alcoholic solvent, which provides higher lung deposition compared to other pharmaceutical forms. The formulation is free of propellant, stabilizing agents, and preservatives, and is suitable for use in a soft mist inhaler.

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