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Charged Depth Filtration Of Antigen-Binding Proteins

Patent No. EP4209499 (titled "Charged Depth Filtration Of Antigen-Binding Proteins") was filed by Amgen on Aug 12, 2016. The application was issued on Aug 7, 2024.

Patent Summary

Methods for producing stable aqueous formulations of therapeutic antibodies by re-oxidizing reduced antibody molecules using charged depth filtration. The method involves contacting an aqueous solution containing reduced antibody molecules with a charged depth filter under conditions that promote re-oxidation, resulting in a formulation with significantly reduced levels of reduced antibody fragments and aggregates.

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Patent Family

Patent Oppositions (7)

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.

CompanyOpposition DateRepresentative
HAMPTON KNOWLESMay 7, 2025D YOUNG
MAIWALDMay 7, 2025MAIWALD
MARGARET DIXONMay 7, 2025MEWBURN ELLIS
WITHERS & ROGERSMay 7, 2025TOMBLING
STRAWMANMay 6, 2025MAIWALD
JAMES POOLEMay 2, 2025CARPMAELS & RANSFORD
HEMSATHSep 23, 2024KONIG SZYNKA TILMANN VON RENESSE PATENTANWALTE PARTNERSCHAFT MBB DUSSELDORF

Dossier Documents

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EP4209499

AMGEN
Application Number
EP22211542A
Filing Date
Aug 12, 2016
Status
Granted And Under Opposition
Jul 5, 2024
Publication Date
Aug 7, 2024
External Links
Slate, Register , Google Patents