Patent No. EP4357457 (titled "Composition For Cleaving A Target Dna Comprising A Guide Rna Specific For The Target Dna And Cas Protein-Encoding Nucleic Acid Or Cas Protein, And Use Thereof") was filed by Toolgen Incorporated on Oct 23, 2013. The application was issued on Oct 16, 2024.

Patent oppositions filed by competitors challenge the validity of a granted patent. These oppositions are typically based on claims of prior art, lack of novelty, or non-obviousness. They are a key part of the process for determining a patent's strength and enforceability.
| Company | Opposition Date | Representative |
|---|---|---|
| GRUND GROUP PATENTANWALTE UND SOLICITOR PARTG MBB | Mar 6, 2025 | GRUND |
| VERTEX PHARMACEUTICALS INCORPORATED | Feb 28, 2025 | CARPMAELS & RANSFORD |
| VOSSIUS & PARTNER PATENTANWALTE RECHTSANWALTE MBB | Oct 16, 2024 | - |
The dossier documents provide a comprehensive record of the patent's prosecution history - including filings, correspondence, and decisions made by patent offices - and are crucial for understanding the patent's legal journey and any challenges it may have faced during examination.
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