Remediation Of Toxins In Biorefinery Process Streams

Patent No. US11800884 (titled "Remediation Of Toxins In Biorefinery Process Streams") was filed by Jpmorgan Chase Bank Na on Feb 8, 2023.

What is this patent about?

’884 is related to the field of biorefineries, specifically addressing the problem of mycotoxin contamination in feedstock used for producing ethanol and other co-products like animal feed. Cereal grains, a common feedstock, can be infected with fungi that produce toxins such as deoxynivalenol (DON), which negatively impacts the value and safety of the resulting co-products. The invention aims to remediate these toxins within the biorefinery process.

The underlying idea behind ’884 is to introduce a toxin mitigant into the biorefinery process stream to react with and neutralize the mycotoxins. This involves adding a treatment compound, such as a sulfur-containing compound, to one or more process streams at various stages of the ethanol production process. The treatment compound reacts with the toxin, converting it into a less toxic or non-toxic form, thereby improving the quality of the co-products.

The claims of ’884 focus on a process for remediating deoxynivalenol (DON). The process involves first determining if DON is present in the incoming grain or biorefinery process compositions by measuring its concentration. If DON is detected, one or more treatment compounds are introduced into at least one post-distillation biorefinery process composition (whole stillage, thin stillage, or syrup). The treatment compounds react with the DON to form reaction products, reducing the DON concentration.

In practice, the treatment compound, often a sulfite or bisulfite solution, is added to the process stream after distillation, preferably to the thin stillage or syrup where the toxins are concentrated. The reaction is facilitated by the aqueous environment and elevated temperatures present in these streams. The treated stream is then allowed a certain dwell time for the reaction to occur before further processing, such as drying to produce DDGS (dried distillers grains with solubles).

This approach differs from prior methods by targeting the toxin remediation within the existing biorefinery process, rather than pre-treating the feedstock or employing separate detoxification steps. By introducing the treatment compound at specific points in the process, particularly after distillation, the invention minimizes interference with fermentation and distillation while maximizing the effectiveness of the toxin mitigation. The system can also be automated, using sensors to monitor toxin levels and adjust the dosage of the treatment compound accordingly, optimizing the process and reducing costs.

How does this patent fit in bigger picture?

Technical landscape at the time

In the late 2010s when '884 was filed, biorefineries at a time when X was typically implemented using Y, where X is the remediation of toxins in biorefinery co-products and Y is the treatment of biorefinery process streams with a toxin mitigant. At that time, process steps commonly relied on Z rather than A, where Z is inputting feedstock, milling, mixing with water, heating, enzymatic hydrolysis, fermenting, collecting fermentation product, separating components, dewatering, and collecting co-products, and A is some other set of process steps. Also, at that time, hardware or software constraints made B non-trivial, where B is the economical and effective reduction or elimination of toxins from biorefinery co-products.

Novelty and Inventive Step

Claims 1-20 were cancelled. Claims 21-50 were pending and rejected. Claims 21-50 were objected to because of informalities. The claims were rejected under 35 U.S.C. 112(a) or 35 U.S.C. 112 (pre-AIA), first paragraph, and under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA), second paragraph, as being indefinite. Claims 21-25, 27-34, 37-40, and 42-50 were rejected under 35 U.S.C. 103 as being unpatentable over Elend et al. in view of Guo et al., and claims 26, 35, 36 and 41 are rejected under 35 U.S.C. 103 as being unpatentable over Elend et al. in view of Guo et al. as applied to claim 21 above, and further in view of Karlovsky et al. The prosecution record does NOT describe the technical reasoning or specific claim changes that led to allowance.

Claims

This patent contains 30 claims, with independent claims 1 and 26. The independent claims are directed to processes for remediating deoxynivalenol in biorefinery process compositions. The dependent claims generally elaborate on specific conditions, components, and steps of the remediation processes described in the independent claims.

Key Claim Terms New

Definitions of key terms used in the patent claims.

Term (Source)Support for SpecificationInterpretation
Post-distillation, biorefinery process composition
(Claim 1, Claim 26)
“Process steps may include one or more of inputting feedstock into the biorefinery, milling the feedstock to a meal or flour, mixing of the milled material with water to form a slurry, heating of the slurry to liquefy one or more components of the slurry, enzymatically hydrolyzing components of the slurry, fermenting the slurry, collecting the fermentation product, separating the fermentation product into different components, collecting fermentation product streams, dewatering, and collecting co-products. Not all of these steps need be used in any particular biorefinery operation.”A composition derived from a biorefinery process after distillation, specifically chosen from whole stillage, thin stillage, syrup, or combinations thereof (Claim 1) or from the first aqueous fraction, the second aqueous fraction, the first oil fraction, the second oil fraction, and combinations thereof (Claim 26).
Reaction products
(Claim 1, Claim 26)
“For example, deoxynivalenol (DON) will react with sodium bisulfite to form sulfonated derivative of DON, termed as DON sulfonate or DONS.”Substances formed when the treatment compounds react with deoxynivalenol.
Treatment compounds
(Claim 1, Claim 26)
“The remediation may involve, for example, introducing a treatment compound into one or more process streams during or between process steps that will react with the toxin. For example, the treatment compound may be a sulfur containing compound such as a sulfate, sulfite, bisulfite, metabisulfite, and others. For example, the treatment compound may be ammonium bisulfite, potassium bisulfite, sodium bisulfite, and others. These compounds will react with some toxins to form less toxic or non-toxic sulfur compounds. For example, deoxynivalenol (DON) will react with sodium bisulfite to form sulfonated derivative of DON, termed as DON sulfonate or DONS.”One or more compounds introduced into a biorefinery process stream to react with mycotoxins, specifically deoxynivalenol, to form reaction products and reduce the concentration of the deoxynivalenol.

Litigation Cases New

US Latest litigation cases involving this patent.

Case NumberFiling DateTitle
2:25-cv-01550Oct 9, 2025POET Research, Inc. v. Hydrite Chemical Company

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US11800884

JPMORGAN CHASE BANK NA
Application Number
US18107163
Filing Date
Feb 8, 2023
Status
Granted
Expiry Date
Jul 31, 2038
External Links
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