The detailed information for PTAB case with proceeding number IPR2015-01093 filed by Coalition for Affordable Drugs II, LLC against NPS Pharmaceuticals, Inc. et al. on Apr 23, 2015. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Case Details

Proceeding Number
IPR2015-01093
Filing Date
Apr 23, 2015
Petitioner
Coalition for Affordable Drugs II, LLC
Respondent
NPS Pharmaceuticals, Inc. et al.
Status
Final Written Decision
Respondent Application Number
09750022
Respondent Tech Center
1600
Respondent Patent Number
7056886
Institution Decision Date
Oct 23, 2015
Termination Date
Oct 21, 2016

Proceeding Documents

The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.


Document NameFiling DateCategoryFiling Party

Alert me when new update on this case

Patent Owner NPS Pharmaceuticals, Inc.'s Notice of Appeal

Dec 20, 2016PAPERPATENT OWNER

Granting PO Motions to Seal and Petitioner Motion to Seal

Oct 21, 2016PAPERBOARD

Termination Decision Document

Oct 21, 2016PAPERBOARD

Record of Oral Hearing

Aug 23, 2016PAPERBOARD

Patent Owner's Updated Exhibit List

Jun 21, 2016PAPERPATENT OWNER

Submission of Petitioner's Demonstrative Exhibit for Oral Argument

Jun 21, 2016PAPERPETITIONER

Petitioner's Updated Exhibit List

Jun 21, 2016PAPERPETITIONER

Petitioner's Demonstrative Exhibit

Jun 21, 2016EXHIBITPETITIONER

Patent Owner's Demonstrative Exhibits

Jun 21, 2016EXHIBITPATENT OWNER

Order - Granting Request for Oral Argument - 37 CFR 42.70

Jun 15, 2016PAPERBOARD

Patent Owner's Response to Introduction In Petitioner's Response to Motion Presenting Patent Owner's Observations Regarding Cross-Examination of Ivan Hofmann

Jun 14, 2016PAPERPATENT OWNER

Patent Owner's Response to Introduction in Petitioner's Response to Motion Presenting Patent Owner's Observations Regarding Cross-Examination of Anthony Palmieri, Ph.D.

Jun 14, 2016PAPERPATENT OWNER

Patent Owner's Reply to Petitioner's Opposition to Motion to Exclude Reply Declaration of Anthony Palmieri III (Ex. 1041)

Jun 1, 2016PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

Jun 1, 2016PAPERPATENT OWNER

Notice of Stipulation Regarding Scheduling Order

May 31, 2016PAPERPETITIONER

Petitioner's Response to Motion Presenting Patent Owner's Observations re Cross-Examination of Ivan Hofmann

May 31, 2016PAPERPETITIONER

Petitioner's Response to Motion Presenting Patent Owner's Observations re Cross-Examination of Anthony Palmieri

May 31, 2016PAPERPETITIONER

Petitioner's Opposition to Patent Owner's Motion to Exclude Reply Declaration of Anthony Palmieri_Ex 1041

May 27, 2016PAPERPETITIONER

Petitioner's Request for Oral Argument

May 18, 2016PAPERPETITIONER

Motion Presenting Patent Owner's Observations Regarding Cross-Examination Of Anthony Palmieri

May 18, 2016PAPERPATENT OWNER

Motion Presenting Patent Owner's Observations Regarding Cross-Examination Of Ivan Hofmann

May 18, 2016PAPERPATENT OWNER

Patent Owner's Motion to Exclude Reply Declaration of Anthony Palmieri III (Ex. 1041)

May 18, 2016PAPERPATENT OWNER

Patent Owner's Motion to Seal

May 18, 2016PAPERPATENT OWNER

Patent Owner's Request for Oral Argument

May 18, 2016PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

May 18, 2016PAPERPATENT OWNER

Part 1 Exhibit 2164 to the Hofmann Deposition Dated May 6, 2016- Medicare formulary

May 18, 2016EXHIBITPATENT OWNER

Part 2 Exhibit 2164 to the Hofmann Deposition Dated May 6, 2016- Medicare formulary

May 18, 2016EXHIBITPATENT OWNER

Part 3 Exhibit 2164 to the Hofmann Deposition Dated May 6, 2016- Medicare formulary

May 18, 2016EXHIBITPATENT OWNER

Part 4 Exhibit 2164 to the Hofmann Deposition Dated May 6, 2016- Medicare formulary

May 18, 2016EXHIBITPATENT OWNER

Part 5 Exhibit 2164 to the Hofmann Deposition Dated May 6, 2016- Medicare formulary

May 18, 2016EXHIBITPATENT OWNER

Exhibit 2167 to the Hofmann Deposition Dated May 6, 2016- Article entitled Complications of Parenteral Nutrition in Gastroenterology Clinics of North America by Ukleja

May 18, 2016EXHIBITPATENT OWNER

Exhibit 2168 to the Hofmann Deposition Dated May 6, 2016- Printout from rebates.com

May 18, 2016EXHIBITPATENT OWNER

Part 1 Exhibit 2169 to the Hofmann Deposition Dated May 6, 2016- Review Article, The Management of Long-Term Parenteral Nutrition, by Dibb and others

May 18, 2016EXHIBITPATENT OWNER

Part 2 Exhibit 2169 to the Hofmann Deposition Dated May 6, 2016- Review Article, The Management of Long-Term Parenteral Nutrition, by Dibb and others

May 18, 2016EXHIBITPATENT OWNER

Exhibit 2170 to the Hofmann Deposition Dated May 6, 2016- Excerpt from the Merck Manual, Fifteenth Edition

May 18, 2016EXHIBITPATENT OWNER

Exhibit 2174 to the Hofmann Deposition Dated May 6, 2016- Memorandum opinion from Intendis GmBH, et al. versus Glenmark Pharmaceuticals Ltd., et al.

May 18, 2016EXHIBITPATENT OWNER

Exhibit 2195 to the Hofmann Deposition Dated May 6, 2016- McKinsey report entitled Insights into Pharmaceuticals and Medical Products

May 18, 2016EXHIBITPATENT OWNER

Exhibit 2196 to the Hofmann Deposition Dated May 6, 2016- Graph of NPS's stock price from 1-1-13 - 5-1-13

May 18, 2016EXHIBITPATENT OWNER

Transcript of Video Deposition of Ivan Hoffmann (Redacted)

May 18, 2016EXHIBITPATENT OWNER

Transcript of Video Deposition of Ivan Hoffmann SEALED

May 18, 2016EXHIBITPATENT OWNER

Transcript of Video Deposition of Anthony Palmieri III, Ph.D. on May 11, 2016

May 18, 2016EXHIBITPATENT OWNER

Exhibit 2197 to the Hofmann Deposition Dated May 6, 2016- Hofmann's Original Graph, Monthly Adjusted Close Stock Price

May 18, 2016EXHIBITPATENT OWNER

Exhibit 2161 to the Hofmann Deposition Dated May 6, 2016- List of drugs from Medicare.gov website Pharmaceutical Assistance Program (Medicare)

May 18, 2016EXHIBITPATENT OWNER

Patent Owner's Notice of of Deposition of Dr. Ivan Hofmann

May 2, 2016PAPERPATENT OWNER

Patent Owner's Second Notice of Deposition of Dr. Anthony Palmieri

May 2, 2016PAPERPATENT OWNER

Patent Owner's Objections to Petitioner's Reply and Exhibit

Apr 27, 2016PAPERPATENT OWNER

Petitioner's Reply to Patent Owner's Response

Apr 20, 2016PAPERPETITIONER

Petitioner's Updated Exhibit List

Apr 20, 2016PAPERPETITIONER

Petitioner's Motion to Seal

Apr 20, 2016PAPERPETITIONER

Reply Declaration of Anthony Palmieri III, Ph.D., R.Ph.

Apr 20, 2016EXHIBITPETITIONER

Reply Declaration of Ivan Hofmann (Confidential)

Apr 20, 2016EXHIBITPETITIONER

Reply Declaration of Ivan Hofmann (Redacted)

Apr 20, 2016EXHIBITPETITIONER

Deposition Transcript of Dr. John Carpenter

Apr 20, 2016EXHIBITPETITIONER

Dr. John Carpenter Deposition Exhibit No. 102

Apr 20, 2016EXHIBITPETITIONER

Dr. John Carpenter Deposition Exhibit No. 104

Apr 20, 2016EXHIBITPETITIONER

Dr. John Carpenter Deposition Exhibit No. 105

Apr 20, 2016EXHIBITPETITIONER

Dr. John Carpenter Deposition Exhibit No. 10

Apr 20, 2016EXHIBITPETITIONER

Dr. John Carpenter Deposition Exhibit No. 109

Apr 20, 2016EXHIBITPETITIONER

Dr. John Carpenter Deposition Exhibit No. 110

Apr 20, 2016EXHIBITPETITIONER

Dr. John Carpenter Deposition Exhibit No. 111

Apr 20, 2016EXHIBITPETITIONER

Manning et al., 1989 Pharm. Res. 6

Apr 20, 2016EXHIBITPETITIONER

Linde et al., Journal of Chromatography

Apr 20, 2016EXHIBITPETITIONER

Yahoo Finance, NBI Pharmaceuticals historical monthly stock prices

Apr 20, 2016EXHIBITPETITIONER

Shire to Acquire NPS Pharmaceuticals for 5.2B

Apr 20, 2016EXHIBITPETITIONER

Shire to Acquire NPS Pharma as Further Step in Building a Leading Biotech

Apr 20, 2016EXHIBITPETITIONER

Shire, 2015, Shire to acquire NPS Pharmaceuticals

Apr 20, 2016EXHIBITPETITIONER

Shire, Half Yearly Report 2015

Apr 20, 2016EXHIBITPETITIONER

Shire, 2015, Shire to acquire NPS Pharmaceuticals

Apr 20, 2016EXHIBITPETITIONER

Shire, 2015 Form 10-K

Apr 20, 2016EXHIBITPETITIONER

Gattex, About Gattex

Apr 20, 2016EXHIBITPETITIONER

Gattex, Why Choose Gattex

Apr 20, 2016EXHIBITPETITIONER

Shire 2014 Annual Report

Apr 20, 2016EXHIBITPETITIONER

Shire, 2016, Creating the global leader in Rare Diseases

Apr 20, 2016EXHIBITPETITIONER

NPS, 2012, FDA Approves Gattex

Apr 20, 2016EXHIBITPETITIONER

OnePath

Apr 20, 2016EXHIBITPETITIONER

Gattex, Patient Support

Apr 20, 2016EXHIBITPETITIONER

FDA Search Orphan Drug Designations and Approvals

Apr 20, 2016EXHIBITPETITIONER

Fox Business Why One Drug Costs 295K a Year

Apr 20, 2016EXHIBITPETITIONER

FDA Frequently Asked Questions FAQ Regarding

Apr 20, 2016EXHIBITPETITIONER

FDA Small Business Assistance

Apr 20, 2016EXHIBITPETITIONER

Curriculum vitae of Ivan T. Hofmann

Apr 20, 2016EXHIBITPETITIONER

U.S. Patent No. 7,847,061 B2

Apr 20, 2016EXHIBITPETITIONER

FDA Approved Drug Products Zorbtive

Apr 20, 2016EXHIBITPETITIONER

Patient Assistance Program

Apr 20, 2016EXHIBITPETITIONER

NPS List of Subsidiaries

Apr 20, 2016EXHIBITPETITIONER

Gattex Orange Book

Apr 20, 2016EXHIBITPETITIONER

Deposition Transcript of Gordon Rausser, Ph.D. (CONFIDENTIAL)

Apr 20, 2016EXHIBITPETITIONER

Deposition Transcript of Gordon Rausser, Ph.D. (REDACTED)

Apr 20, 2016EXHIBITPETITIONER

U.S. Patent No. 9,060,992

Apr 20, 2016EXHIBITPETITIONER

FDA Orphan Products Hope for People With Rare Diseases

Apr 20, 2016EXHIBITPETITIONER

Pharmacy and Therapeutics Committees in managed care organizations

Apr 20, 2016EXHIBITPETITIONER

Tiger in the Fiscal Room

Apr 20, 2016EXHIBITPETITIONER

Gattex Gains Approval in SBS

Apr 20, 2016EXHIBITPETITIONER

Yahoo Finance NPS Pharmaceuticals historical monthly stock prices

Apr 20, 2016EXHIBITPETITIONER

Yahoo Finance XBI Pharmaceuticals historical monthly stock prices

Apr 20, 2016EXHIBITPETITIONER

FDA Approves Gattex to treat short bowel syndrome

Apr 20, 2016EXHIBITPETITIONER

Dr. Gordon Rausser Deposition Exhibit No. 8

Apr 20, 2016EXHIBITPETITIONER

Dr. Gordon Rausser Deposition Exhibit No. 9

Apr 20, 2016EXHIBITPETITIONER

Dr. Gordon Rausser Deposition Exhibit No. 10

Apr 20, 2016EXHIBITPETITIONER

U.S. Patent No. 5,656,730

Apr 20, 2016EXHIBITPETITIONER

Dr. John Carpenter Deposition Exhibit No. 103

Apr 20, 2016EXHIBITPETITIONER

Petitioner's Notice of Deposition of John F. Carpenter, Ph.D.

Mar 22, 2016PAPERPETITIONER

Petitioner's Notice of Deposition of Gordon Rausser, Ph.D.

Mar 22, 2016PAPERPETITIONER

Second Notice of Stipulated Change to Scheduling Order

Feb 17, 2016PAPERPATENT OWNER

Corrected Rodrigues 2011 - Short Bowel Syndrome

Feb 17, 2016EXHIBITPATENT OWNER

Corrected NPS 2014 10-K

Feb 17, 2016EXHIBITPATENT OWNER

Corrected Shire 2015 - SHPG Flemming Ornskov on Q3 2015 Results - Earnings Call Transcript

Feb 17, 2016EXHIBITPATENT OWNER

Corrected Seeking Alpha 2013 - NPS Pharmaceuticals CEO Discusses

Feb 17, 2016EXHIBITPATENT OWNER

Corrected Merck 2014 - Annual Report

Feb 17, 2016EXHIBITPATENT OWNER

Corrected Merck 2009 - Annual Report

Feb 17, 2016EXHIBITPATENT OWNER

Corrected Part 1 Merck 2010 - Annual Report

Feb 17, 2016EXHIBITPATENT OWNER

Corrected Part 2 Merck 2010 - Annual Report

Feb 17, 2016EXHIBITPATENT OWNER

Patent Owner's Motion to Deem the Filing of Patent Owner's Exhibits 2042-2055, 2057-2074, and 2076-2149 as Timely

Jan 29, 2016PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

Jan 29, 2016PAPERPATENT OWNER

PRPS Email 1/20/16 1130 PM

Jan 29, 2016EXHIBITPATENT OWNER

PRPS Email 1/20/16 1135 PM

Jan 29, 2016EXHIBITPATENT OWNER

PRPS Email 1/20/16 1142 PM

Jan 29, 2016EXHIBITPATENT OWNER

PRPS Email 1/20/16 1149 PM

Jan 29, 2016EXHIBITPATENT OWNER

PRPS Email 1/20/16 1158 PM

Jan 29, 2016EXHIBITPATENT OWNER

PRPS Email 1/21/16 1202 AM

Jan 29, 2016EXHIBITPATENT OWNER

PRPS Email 1/21/16 350 AM

Jan 29, 2016EXHIBITPATENT OWNER

PRPS Email 1/21/16 225 AM

Jan 29, 2016EXHIBITPATENT OWNER

Declaration of Joseph R. Robinson

Jan 29, 2016EXHIBITPATENT OWNER

Declaration of Matthew Hu

Jan 29, 2016EXHIBITPATENT OWNER

Petitioners Objections to Patent Owners Exhibits Submitted wth Its Patent Owners Response

Jan 27, 2016PAPERPETITIONER

Petitioner's Updated Mandatory Notice Pursuant to 37 C.F.R. 42.8

Jan 21, 2016PAPERPETITIONER

Transcript of Deposition of Anthony Palmieri III, Ph.D

Jan 21, 2016EXHIBITPATENT OWNER

CV of John F. Carpenter, Ph.D.

Jan 21, 2016EXHIBITPATENT OWNER

CV of Gordon Rausser, Ph.D.

Jan 21, 2016EXHIBITPATENT OWNER

Jackson 2012

Jan 21, 2016EXHIBITPATENT OWNER

Onoue 2004

Jan 21, 2016EXHIBITPATENT OWNER

U.S. Pharmacopeia 24, 774-77 (1999)

Jan 21, 2016EXHIBITPATENT OWNER

Joshi 2012

Jan 21, 2016EXHIBITPATENT OWNER

Fang 2012

Jan 21, 2016EXHIBITPATENT OWNER

Blundell 1983

Jan 21, 2016EXHIBITPATENT OWNER

Boesch 1978

Jan 21, 2016EXHIBITPATENT OWNER

Akers 2002

Jan 21, 2016EXHIBITPATENT OWNER

U.S. Pharmacopeia 788 (2011)

Jan 21, 2016EXHIBITPATENT OWNER

Remington's Pharmaceutical Sciences, 18th Ed., 1549-51 (1990)

Jan 21, 2016EXHIBITPATENT OWNER

U.S. Patent Publication No. 2013/0310314

Jan 21, 2016EXHIBITPATENT OWNER

Annex1 Summary of Product Characteristics

Jan 21, 2016EXHIBITPATENT OWNER

Orange Book Listing for Gattex

Jan 21, 2016EXHIBITPATENT OWNER

Eli Lilly and Co. 2012

Jan 21, 2016EXHIBITPATENT OWNER

Al-Hussein 2013

Jan 21, 2016EXHIBITPATENT OWNER

Izutsu 2009

Jan 21, 2016EXHIBITPATENT OWNER

U.S. Pharmacopeia 23, 1650-51 (1995)

Jan 21, 2016EXHIBITPATENT OWNER

Center for Drug Evaluation and Research, Application Number203441Orig1s000, Chemistry Review(s)

Jan 21, 2016EXHIBITPATENT OWNER

FDA - Approved Drug Products Zorbtive

Jan 21, 2016EXHIBITPATENT OWNER

Shire 2015 - Shire Completes Acquisition of NPS Pharma

Jan 21, 2016EXHIBITPATENT OWNER

Engellenner 2015 - Bass Goes Fishing

Jan 21, 2016EXHIBITPATENT OWNER

Joseph Walker and Rob Copeland, New Hedge Fund Strategy WSJ Article_4.7.2015

Jan 21, 2016EXHIBITPATENT OWNER

Wieczner 2015 - Why drug price controversey is great news for this hedge fund manager

Jan 21, 2016EXHIBITPATENT OWNER

Buchman 2006 - Etiology and Initial Management of SBS

Jan 21, 2016EXHIBITPATENT OWNER

Pirona 2015 - Espen endorsed recommendations

Jan 21, 2016EXHIBITPATENT OWNER

O'Keefe 2006 - Short bowel syndrome and intestinal failure

Jan 21, 2016EXHIBITPATENT OWNER

Buchman 1997 - The Clinical Management of Short Bowel Syndrome

Jan 21, 2016EXHIBITPATENT OWNER

NPS 2012 - Developing orphan products for patients

Jan 21, 2016EXHIBITPATENT OWNER

Hofstetter 2013 - Key Issues in Addressing The Clinical and Humanistic

Jan 21, 2016EXHIBITPATENT OWNER

O'Keefe 2015 - Nutritional Issues in the SBS

Jan 21, 2016EXHIBITPATENT OWNER

Tee 2011 - Emerging Treatment Options for SBS - Potential Role of Teduglutide

Jan 21, 2016EXHIBITPATENT OWNER

Naberhuis 2015 - Teduglutide for Safe Reduction of Parenteral Nutrient

Jan 21, 2016EXHIBITPATENT OWNER

Buchman 2012 - Teduglutide and SBS

Jan 21, 2016EXHIBITPATENT OWNER

FDA - Approved Drug Products Zorbtive

Jan 21, 2016EXHIBITPATENT OWNER

Crohn's and Colitis 2013 - Short Bowel Syndrome and Crohn's Disease

Jan 21, 2016EXHIBITPATENT OWNER

Donohoe 2010 - Short Bowel Syndrome

Jan 21, 2016EXHIBITPATENT OWNER

Zorbtive label

Jan 21, 2016EXHIBITPATENT OWNER

Wales 2010 - Human growth hormone and glutamine

Jan 21, 2016EXHIBITPATENT OWNER

Serono 2005 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Part 1 Merck 2013 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Part 2 Merck 2013 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Keller 2004 - Management of the Short Bowel Syndrome after Extensive Small Bowel Resection

Jan 21, 2016EXHIBITPATENT OWNER

Gattex label

Jan 21, 2016EXHIBITPATENT OWNER

Oley Foundation 1994 - North American Home Parenteral

Jan 21, 2016EXHIBITPATENT OWNER

NPS 2011 - NPS Pharmaceuticals Announces Completion of Treatment Phase in STEPS

Jan 21, 2016EXHIBITPATENT OWNER

Seeking Alpha - CEO Discusses Q1 2013 Results

Jan 21, 2016EXHIBITPATENT OWNER

Amiot 2013 - Determinants of home parenteral nutrition dependence

Jan 21, 2016EXHIBITPATENT OWNER

McKeage 2015 - Teduglutide - A Guide to its Use in SBS

Jan 21, 2016EXHIBITPATENT OWNER

FDA 2015 - Orange Book Approved Drug Products with Therapeutic Equivalence Evaluations

Jan 21, 2016EXHIBITPATENT OWNER

Jeppesen 2014 - Spectrum of short bowel syndrome in adults - Intestinal insufficiency to intestinal failure

Jan 21, 2016EXHIBITPATENT OWNER

AGA 2003 - Technical Review on Short Bowl Syndrome and Intestinal Transplantation

Jan 21, 2016EXHIBITPATENT OWNER

Jeppesen 1999 - Quality of life in patients receiving home parenteral nutrition

Jan 21, 2016EXHIBITPATENT OWNER

Jeppesen 2011 - Randomised placebo-controlled trial of teduglutide in

Jan 21, 2016EXHIBITPATENT OWNER

ADA 2013 - Economic Cost of Diabetes in the US in 2012

Jan 21, 2016EXHIBITPATENT OWNER

Rodrigues 2011 - Short Bowel Syndrome

Jan 21, 2016EXHIBITPATENT OWNER

Thompson 2012 - Current Management of SBS

Jan 21, 2016EXHIBITPATENT OWNER

Jeppesen 2012 - Teduglutide Reduces Need for Parenteral Support Among Patients with SBS

Jan 21, 2016EXHIBITPATENT OWNER

Seeking Alpha - CEO Discusses Q2 2013 Results

Jan 21, 2016EXHIBITPATENT OWNER

Seeking Alpha - CEO Discusses Q3 2013 Results

Jan 21, 2016EXHIBITPATENT OWNER

Seeking Alpha - CEO Discusses Q4 2013 Results

Jan 21, 2016EXHIBITPATENT OWNER

Shire 2015 - Q3 2015 Results

Jan 21, 2016EXHIBITPATENT OWNER

Shire 2015 - Q3 2015 Results

Jan 21, 2016EXHIBITPATENT OWNER

Wolters Kluwer Price Data

Jan 21, 2016EXHIBITPATENT OWNER

NPS Pharmaceuticals' (NPSP) CEO Francois Nader on Q1 2014 Results - Earnings Call Transcript

Jan 21, 2016EXHIBITPATENT OWNER

Seeking Alpha - CEO Francois Nader on Q2 2014 Results

Jan 21, 2016EXHIBITPATENT OWNER

Seeking Alpha - CEO Francois Nader on Q3 2014 Results

Jan 21, 2016EXHIBITPATENT OWNER

NPS 2014 10-K

Jan 21, 2016EXHIBITPATENT OWNER

Shire 2015 - Q1 2015 Results

Jan 21, 2016EXHIBITPATENT OWNER

Shire 2015 - Q2 2015 results

Jan 21, 2016EXHIBITPATENT OWNER

Shire 2015 - SHPG Flemming Ornskov on Q3 2015 Results - Earnings Call Transcript

Jan 21, 2016EXHIBITPATENT OWNER

Seeking Alpha 2013 - NPS Pharmaceuticals CEO Discusses

Jan 21, 2016EXHIBITPATENT OWNER

Yahoo Finance - NPSP Historical Prices

Jan 21, 2016EXHIBITPATENT OWNER

NPS 2013 10-K

Jan 21, 2016EXHIBITPATENT OWNER

Moon 2014 - Biotech selloff could be harbinger of further decline Reuters

Jan 21, 2016EXHIBITPATENT OWNER

Ashton 2014 - Biotech Sell Off Drags NASDAQ-100 Down To 2-Year Lows

Jan 21, 2016EXHIBITPATENT OWNER

Nasdaq - Overview for NBI

Jan 21, 2016EXHIBITPATENT OWNER

Yahoo Finance - NBI Historical Prices

Jan 21, 2016EXHIBITPATENT OWNER

Yahoo Finance - XBI Historical Prices

Jan 21, 2016EXHIBITPATENT OWNER

Shire - Patient Assistance Program Gattex

Jan 21, 2016EXHIBITPATENT OWNER

SP Capital IQ 2014 - NPS Pharmaceuticals (NPSP)

Jan 21, 2016EXHIBITPATENT OWNER

Osbourne 2014 - Natpara sails through panel despite headwind

Jan 21, 2016EXHIBITPATENT OWNER

Shire 2015 - Q1 2015 10-Q

Jan 21, 2016EXHIBITPATENT OWNER

FDA 2015 - Expiration Dating and Stability Testing for Human

Jan 21, 2016EXHIBITPATENT OWNER

Gibson 2009 - Pharmaceutical Preformulation and Formulation

Jan 21, 2016EXHIBITPATENT OWNER

Cohen 2000 - Many medicines are potent years past expiration dates

Jan 21, 2016EXHIBITPATENT OWNER

Merck 2014 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

FDA CDER - Initial Quality Assessment

Jan 21, 2016EXHIBITPATENT OWNER

Herper 2012 - Inside The Secret World Of Drug Company Rebates - Forbes

Jan 21, 2016EXHIBITPATENT OWNER

Shire - Sharps Disposal Gattex

Jan 21, 2016EXHIBITPATENT OWNER

Shire - OnePath Support Program

Jan 21, 2016EXHIBITPATENT OWNER

Klick Health - Patient Support Programs

Jan 21, 2016EXHIBITPATENT OWNER

FDA 2014 - Guidance on Devices for Home Use

Jan 21, 2016EXHIBITPATENT OWNER

FDA - Approved Drug Products Gattex

Jan 21, 2016EXHIBITPATENT OWNER

Adempas (riociguat) - Aim Patient Support Program Overview

Jan 21, 2016EXHIBITPATENT OWNER

Celgene - Patient Support

Jan 21, 2016EXHIBITPATENT OWNER

Merck 2006 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Merck 2007 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Merck 2008 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Merck 2009 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Part 1 Merck 2010 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Part 2 Merck 2010 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Part 1 Merck 2011 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Part 2 Merck 2011 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Merck 2012 - Annual Report

Jan 21, 2016EXHIBITPATENT OWNER

Declaration of John F. Carpenter, Ph.D. in Support of Patent Owner's Response (Redacted)

Jan 21, 2016EXHIBITPATENT OWNER

Declaration of Gordon Rausser, Ph.D. in Support of Patent Owner's Response to the Petition (Redacted)

Jan 21, 2016EXHIBITPATENT OWNER

Patent Owner's Response

Jan 20, 2016PAPERPATENT OWNER

Patent Owner's Combined Motion to Seal and Entry of Protective Order

Jan 20, 2016PAPERPATENT OWNER

Declaration of Gordon Rausser, Ph.D. n Support of Patent Owner's Response to the Petition

Jan 20, 2016EXHIBITPATENT OWNER

Protective Order

Jan 20, 2016EXHIBITPATENT OWNER

Declaration of John F. Carpenter, Ph.D. in Support of Patent Owner's Response

Jan 20, 2016EXHIBITPATENT OWNER

Carpenter Signature Page

Jan 20, 2016EXHIBITPATENT OWNER

Process Validation and/or Evaluation for Gattex

Jan 20, 2016EXHIBITPATENT OWNER

Shire, Gattex Physician ATU Final Report, October 22, 2015

Jan 20, 2016EXHIBITPATENT OWNER

Order Conduct of the Proceeding

Dec 14, 2015PAPERBOARD

Notice of Stipulation Regarding Scheduling Order

Dec 3, 2015PAPERPATENT OWNER

Notice of Deposition of Dr. Anthony Palmieri

Nov 18, 2015PAPERPATENT OWNER

Decision Patent Owner's Request for Rehearing

Oct 23, 2015PAPERBOARD

Decision Institution of Inter Partes Review

Oct 23, 2015PAPERBOARD

Scheduling Order

Oct 23, 2015PAPERBOARD

Order Conduct of the Proceeding

Sep 23, 2015PAPERBOARD

Petitioner's Brief in Response to the Board's Request for Additional Briefing

Sep 21, 2015PAPERPETITIONER

Petitioner's Updated Exhibit List

Sep 21, 2015PAPERPETITIONER

NPS Pharmaceuticals, Inc., Annual Report 10-K

Sep 21, 2015EXHIBITPETITIONER

Declaration of Professor Marc I. Steinberg, J.D., LL.M

Sep 21, 2015EXHIBITPETITIONER

Joint letter from AARP, AHIP, BCBSA and PCMA to Chairmen Grassley and Goodlatte and Ranking Members Leahy and Conyers

Sep 21, 2015EXHIBITPETITIONER

Dean Baker, The Impact of Exempting the Pharmaceutical Industry from Patent Reviews, Center for Economic and Policy Research

Sep 21, 2015EXHIBITPETITIONER

Orange Book_Approved Drug Products with Therapeutic Equivalence Evaluations_Gattex

Sep 21, 2015EXHIBITPETITIONER

Matthew Herper, Inside the Pricing of a 300,000 A Year Drug, Forbes

Sep 21, 2015EXHIBITPETITIONER

Corrected Patent Owner Brief In Response to Board Request for Additional Briefing

Sep 14, 2015PAPERPATENT OWNER

Patent Owner s Brief In Response to the Board s Request For Additional Briefing

Sep 10, 2015PAPERPATENT OWNER

Order - re Additional Briefing

Sep 1, 2015PAPERBOARD

Patent Owner's Preliminary Response and Updated Exhibit List

Aug 7, 2015PAPERPATENT OWNER

GATTEX Product Label

Aug 7, 2015EXHIBITPATENT OWNER

Lehninger et al., Principles of Biochemistry, 2nd ed., Chapters 5-7 and 18, pp. 111-197 and 542-597 (1993)

Aug 7, 2015EXHIBITPATENT OWNER

Part 1 - Voet and Voet, Biochemistry, 2nd ed., Chapters 7 and 14, pp. 141-90 and 371-410 (1995)

Aug 7, 2015EXHIBITPATENT OWNER

Part 2 - Voet and Voet, Biochemistry, 2nd ed., Chapters 7 and 14, pp. 141-90 and 371-410 (1995)

Aug 7, 2015EXHIBITPATENT OWNER

Part 3 - Voet and Voet, Biochemistry, 2nd ed., Chapters 7 and 14, pp. 141-90 and 371-410 (1995)

Aug 7, 2015EXHIBITPATENT OWNER

Purves et al., Life The Science of Biology, 3rd ed., Ch. 3, pp. 40-59 (1992)

Aug 7, 2015EXHIBITPATENT OWNER

NPS Pharmaceuticals , Inc. Form10-K 2014

Aug 7, 2015EXHIBITPATENT OWNER

Email from Jeff Blake to Counsel for Patent Owner

Aug 7, 2015EXHIBITPATENT OWNER

Declaration of Christopher E. Kirkpatrick

Aug 7, 2015EXHIBITPATENT OWNER

Declaration of Erich Spangenberg

Aug 7, 2015EXHIBITPATENT OWNER

The Wall Street Journal - New Hedge Fund Strategy Challenge the Patent, Short the Stock

Aug 7, 2015EXHIBITPATENT OWNER

The Wall Street Journal - Innovate or Else Kyle Bass Strikes Again and Challenges Shire Patents

Aug 7, 2015EXHIBITPATENT OWNER

Hayman Capital Management, L.P. Form ADV Part 2A Brochure

Aug 7, 2015EXHIBITPATENT OWNER

Brubaker and Drucker, Structure-Function of the Glucagon Receptor Family of G-Protein Coupled Receptors The Glucagon, GIP, GLP-1, and GLP-2 Receptors, Receptors and Channels, vol. 8, pp. 179-188 (2002)

Aug 7, 2015EXHIBITPATENT OWNER

Chaturvedi, A Report on Stability of Polypeptides and Proteins, Birla Institute of Technology and Science Pilani (Rajasthan) (August 2009)

Aug 7, 2015EXHIBITPATENT OWNER

Vassilatis et al., The G protein-coupled receptor repertoires of human and mouse, Proc Natl Acad Sci USA 100 (8) 4903-4908 (2003)

Aug 7, 2015EXHIBITPATENT OWNER

Petitioner's Motion for Admission Pro Hac Vice of Brent E. Routman

Jul 20, 2015PAPERPETITIONER

Petitioner's Updated Exhibit List

Jul 20, 2015PAPERPETITIONER

Certificate of Service

Jul 20, 2015PAPERPETITIONER

Declaration of Brent E. Routman in Support of Motion for Admission Pro Hac Vicw

Jul 20, 2015EXHIBITPETITIONER

Patent Owner's Motion for Rehearing

Jul 13, 2015PAPERPATENT OWNER

Order Granting-in-Part Patent Owner's Motion for Additional Discovery

Jul 2, 2015PAPERBOARD

Patent Owner's Reply to Petitioner's Opposition to Patent Owner's Motion for Additional Discovery

Jun 15, 2015PAPERPATENT OWNER

Opposition to Patent Owner's Motion for Additional Discovery

Jun 10, 2015PAPERPETITIONER

Petitioner's Updated Exhibit List

Jun 10, 2015PAPERPETITIONER

Shire Development IPR Petition

Jun 10, 2015EXHIBITPETITIONER

Shire Federal Circuit Brief

Jun 10, 2015EXHIBITPETITIONER

Patent Owner's Motion for Additional Discovery

Jun 3, 2015PAPERPATENT OWNER

Patent Owner's Exhibit List

Jun 3, 2015PAPERPATENT OWNER

NPS Pharmaceuticals, Inc.'s Requests for Production to Petitioner

Jun 3, 2015EXHIBITPATENT OWNER

NPS Pharmaceuticals, Inc.'s Interrogatories to Petitioner

Jun 3, 2015EXHIBITPATENT OWNER

NPS Pharmaceuticals, Inc.'s Topics for Examination of Petitioner

Jun 3, 2015EXHIBITPATENT OWNER

General Hedge Fund Structure and Regulation

Jun 3, 2015EXHIBITPATENT OWNER

RPI Diagram

Jun 3, 2015EXHIBITPATENT OWNER

Form ADV Brochure of HCM (Mar. 30, 2015)

Jun 3, 2015EXHIBITPATENT OWNER

Form ADV of HCM (Mar. 30, 2015)

Jun 3, 2015EXHIBITPATENT OWNER

Annual Report of HCM (July 8, 2013)

Jun 3, 2015EXHIBITPATENT OWNER

Amended Form D of HCOP (May 12, 2014)

Jun 3, 2015EXHIBITPATENT OWNER

Amended Form D of HCP (May 12, 2014)

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Credes Onshore Form D (Jan. 14, 2015)

Jun 3, 2015EXHIBITPATENT OWNER

Credes Onshore Delaware Secretary of State Website Printout

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HCMF Cayman Islands Search Report

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Credes Offshore Form D (Jan. 14, 2015)

Jun 3, 2015EXHIBITPATENT OWNER

Credes Offshore Caymans Search Report

Jun 3, 2015EXHIBITPATENT OWNER

Form D of HOF (April 9, 2015)

Jun 3, 2015EXHIBITPATENT OWNER

Certificate of Formation of IPNav (Nov. 13, 2007)

Jun 3, 2015EXHIBITPATENT OWNER

Certificate of Formation of nXnP (Sept. 24, 2014)

Jun 3, 2015EXHIBITPATENT OWNER

Ed Silverman, Innovate or Else - Kyle Bass Strikes Again and Challenges

Jun 3, 2015EXHIBITPATENT OWNER

Robert Cyran, Kyle Bass Wields New Weapon in Challenging Drug

Jun 3, 2015EXHIBITPATENT OWNER

Joseph Walker and Rob Copeland, New Hedge Fund Strategy

Jun 3, 2015EXHIBITPATENT OWNER

Julia La Roche, Hedge Fund Manager Business Insider Article 20150107

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Julia La Roche, Hedge Fund Manager Business Insider Article 20150108

Jun 3, 2015EXHIBITPATENT OWNER

Delaware Secretary of State Business Entity Search Printout for Coalition Entities

Jun 3, 2015EXHIBITPATENT OWNER

Cayman Islands Search Report of HOM

Jun 3, 2015EXHIBITPATENT OWNER

Cayman Islands Search Report of HOF

Jun 3, 2015EXHIBITPATENT OWNER

Order Conduct of the Proceeding

Jun 2, 2015PAPERBOARD

Notice of Filing Date Accorded to Petition

May 7, 2015PAPERBOARD

Power of Attorney

May 6, 2015PAPERINDICATES ARTIFACT WAS SUBMITTED ON BEHALF OF POTENTIAL_PATENT OWNER.

Related Matters

May 6, 2015PAPERINDICATES ARTIFACT WAS SUBMITTED ON BEHALF OF POTENTIAL_PATENT OWNER.

Petition for Inter Partes Review of U.S. Patent No. 7,056,886 (Claims 1-45)

Apr 23, 2015PAPERPETITIONER

Appendix of Exhibits

Apr 23, 2015PAPERPETITIONER

Power of Attorney

Apr 23, 2015PAPERPETITIONER

Declaration of Dr. Anthony Palmieri

Apr 23, 2015EXHIBITPETITIONER

CV of Dr. Palmieri

Apr 23, 2015EXHIBITPETITIONER

U.S. Patent No. 7,056,886 to Isaacs

Apr 23, 2015EXHIBITPETITIONER

U.S. Patent Application Ser. No. 09/750,022

Apr 23, 2015EXHIBITPETITIONER

U.S. Patent No.5,496,801 to Holthuis et al.

Apr 23, 2015EXHIBITPETITIONER

U.S. Patent No.6,120,761 to Yamazaki et al.

Apr 23, 2015EXHIBITPETITIONER

March 8, 2002 Non Final Office Action

Apr 23, 2015EXHIBITPETITIONER

June 10, 2002 Amendment and Reply

Apr 23, 2015EXHIBITPETITIONER

February 5, 2003 Non Final Office Action

Apr 23, 2015EXHIBITPETITIONER

July 9, 2003 Amendment and Reply

Apr 23, 2015EXHIBITPETITIONER

September 16, 2003 Non Final Office Action

Apr 23, 2015EXHIBITPETITIONER

March 16, 2004 Amendment and Reply

Apr 23, 2015EXHIBITPETITIONER

June 8, 2004 Final Office Action

Apr 23, 2015EXHIBITPETITIONER

September 7, 2004 Amendment and Reply

Apr 23, 2015EXHIBITPETITIONER

October 4, 2004 Non Final Office Action

Apr 23, 2015EXHIBITPETITIONER

January 4, 2005 Amendment and Reply

Apr 23, 2015EXHIBITPETITIONER

April 4, 2005 Notice of Allowance and Fee(s) Due

Apr 23, 2015EXHIBITPETITIONER

The Glucagon-Like Peptides Endocrine Reviews 20(6)

Apr 23, 2015EXHIBITPETITIONER

Thermodynamic Model of Secondary Structure for a-Helical Peptides and Proteins

Apr 23, 2015EXHIBITPETITIONER

Structural Determinants for Activity of Glucagon-like Peptide-2

Apr 23, 2015EXHIBITPETITIONER

Regulation of the biological activity of glucagon-like peptide 2 in vivo by dipeptidyl peptidase IV

Apr 23, 2015EXHIBITPETITIONER

Prototypic G-protein coupled receptor for the intestinotrophic factor glucagon like peptide 2

Apr 23, 2015EXHIBITPETITIONER

Gly2 GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis

Apr 23, 2015EXHIBITPETITIONER

Formulation and Delivery of Proteins and Peptides

Apr 23, 2015EXHIBITPETITIONER

WO 99/043361 to Knudsen

Apr 23, 2015EXHIBITPETITIONER

U.S. Patent No. 4,985,244 to Makino

Apr 23, 2015EXHIBITPETITIONER

U.S. Patent No. 5,652,216 to Kornfelt et al.

Apr 23, 2015EXHIBITPETITIONER

PCT Publication WO98/03547

Apr 23, 2015EXHIBITPETITIONER

U.S. Patent No. 5,789,379 to Drucker et al.

Apr 23, 2015EXHIBITPETITIONER

Physical state of L-histidine after freeze drying and long-term storage

Apr 23, 2015EXHIBITPETITIONER

The Science and Practice of Pharmacy Vol.II

Apr 23, 2015EXHIBITPETITIONER