Petitioner's Notice of Appeal | Apr 10, 2018 | PAPER | PETITIONER |
Petitioner's Updated Mandatory Notices | Feb 28, 2018 | PAPER | PETITIONER |
Termination Decision Document | Feb 7, 2018 | PAPER | BOARD |
Order - 37 C.F.R. 42.5, 42.10(e) | Feb 7, 2018 | PAPER | BOARD |
Hearing Transcript | Dec 1, 2017 | PAPER | BOARD |
Order Granting Patent Owner Motion for Pro Hac Vice Admission of Henry Huang | Nov 2, 2017 | PAPER | BOARD |
Petitioner's Motion to Withdraw Counsel | Nov 2, 2017 | PAPER | PETITIONER |
Corrected Declaration of Henry Huang | Nov 1, 2017 | EXHIBIT | PATENT OWNER |
Certificate of Service | Nov 1, 2017 | PAPER | PATENT OWNER |
Order Request for Oral Argument | Oct 23, 2017 | PAPER | BOARD |
Patent Owners Reply in Support of its Motion to Exclude Evidence | Oct 23, 2017 | PAPER | PATENT OWNER |
Unopposed Motion for Pro Hac Vice Admission of Henry Huang | Oct 20, 2017 | PAPER | PATENT OWNER |
EXPUNGED | Oct 20, 2017 | EXHIBIT | PATENT OWNER |
Petitioner's Response to Patent Owner's Motion to Exclude Evidence | Oct 16, 2017 | PAPER | PETITIONER |
Decision of the Court of the Hague | Oct 9, 2017 | EXHIBIT | PETITIONER |
Petitioner's Updated Exhibit List | Oct 9, 2017 | PAPER | PETITIONER |
Patent Owners Surreply to Petitioners Reply | Oct 5, 2017 | PAPER | PATENT OWNER |
Patent Owners Submission of Transcript of Telephone Conference on September 29, 2017 | Oct 5, 2017 | PAPER | PATENT OWNER |
Conduct of the Proceeding | Oct 4, 2017 | PAPER | BOARD |
Patent Owners Motion to Exclude Evidence | Oct 2, 2017 | PAPER | PATENT OWNER |
Patent Owners Request for Oral Hearing | Oct 2, 2017 | PAPER | PATENT OWNER |
Petitioner's Request for Oral Argument | Oct 2, 2017 | PAPER | PETITIONER |
Patent Owners Objections to Petitioners Reply Exhibits | Sep 25, 2017 | PAPER | PATENT OWNER |
Petitioner's Reply to Patent Owner's Response | Sep 18, 2017 | PAPER | PETITIONER |
Shoemaker Deposition Transcript | Sep 18, 2017 | EXHIBIT | PETITIONER |
Petitioner's Reply to Patent Owner's Response | Sep 18, 2017 | PAPER | PETITIONER |
Zizic Deposition Transcript | Sep 18, 2017 | EXHIBIT | PETITIONER |
Correspondence Between Counsel for Petition and Patent Owner | Sep 18, 2017 | EXHIBIT | PETITIONER |
Decision of UK High Court | Sep 18, 2017 | EXHIBIT | PETITIONER |
Report on Court of the Hague Decision | Sep 18, 2017 | EXHIBIT | PETITIONER |
Non-Final Rejection of Application 14/635,542 | Sep 18, 2017 | EXHIBIT | PETITIONER |
Notice of Abandonment of Application 14/635,542 | Sep 18, 2017 | EXHIBIT | PETITIONER |
Joint Stipulation to Further Modify Due Date 2 | Sep 8, 2017 | PAPER | PETITIONER |
Petitioner's Updated Power of Attorney | Aug 23, 2017 | PAPER | PETITIONER |
Petitioner's Updated Mandatory Notices | Aug 23, 2017 | PAPER | PETITIONER |
Order - Granting Petitioner's Motion for Admission Pro Hac Vice of Kayvan B. Noroozi - 37 CFR 42.10(c) | Aug 22, 2017 | PAPER | BOARD |
Motion for Admission Pro Hac Vice of Kayvan Noroozi | Aug 18, 2017 | PAPER | PETITIONER |
Declaration of Kayvan Noroozi | Aug 18, 2017 | EXHIBIT | PETITIONER |
Petitioner's Updated Exhibit List | Aug 18, 2017 | PAPER | PETITIONER |
PATENT OWNER¿¿¿S SUPPLEMENTAL MANDATORY NOTICE | Aug 11, 2017 | PAPER | PATENT OWNER |
Petitioner's Notice of Zizic Deposition | Aug 11, 2017 | PAPER | PETITIONER |
Petitioner's Notice of Clark Deposition | Aug 11, 2017 | PAPER | PETITIONER |
Petitioner's Notice of Massarotti Deposition | Aug 11, 2017 | PAPER | PETITIONER |
Petitioner's Notice of Shoemaker Deposition | Aug 11, 2017 | PAPER | PETITIONER |
Drugs@FDA FDA Approved Drug Products | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Schiff, Head-to-head, randomised, crossover study of oral versus subcutaneous methotrexate in patients with rheumatoid arthritis | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Borchers, The Use of Methotrexate in Rheumatoid Arthritis | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Grim, Pharmacokinetics and Pharmacodynamics of Methotrexate in Non-Neoplastic Diseases | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Bingham, Parenteral methotrexate should be given before biological therapy | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Expert Declaration of Elena Massarotti, M.D. | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
ASP Pricing File 2014 | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Goodman and Gilmans, The Pharmacological Basis of Therapeutics | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
ASP Pricing File 2006 | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
2007 CDC Guidelines for Isolation Precautions Preventing Transmission of Infectious Agents in Healthcare Settings | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
SICOR Pharmaceuticals ANDA Suitability Petition Methotrexate Injection | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Supply of a Cancer Drug | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Brazeau, Current Perspectives on Pain Upon Injection of Drugs | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Antares Pharmas ATRS CEO Paul Wotton on Q1 2014 Results | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Antares Thoughts on the Upcoming Otrexup Launch | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Antares My View of How Otrexup and Medacs New Product Rasuvo May Compete | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Arthritis Today Drug Guide | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
DMARDs for Juvenile Idiopathic Arthritis | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Drug Guide DMARDs | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Parshuram, Occurrence and Impact of Unanticipated Variation in Intravenous Methotrexate Dosing | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
How Medicare Prescription Drug Use | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Declaration of Brian Gummow | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Antares Pharma Press Release | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
About Rasuvo | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Clinical Guidelines Extravasation | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Boyle, Vesicant Extravasation Myths and Realities | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Drugs@FDA Summary Table | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Drugs@FDA Search Results for Methotrexate | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
FDA Approval Letter Otrexup | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
FDA Approval Letter Rasuvo | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Extravasation guidelines 2007 | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
FDA OKs a New Methotrexate Injection Device | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Pavy, Methotrexate therapy for rheumatoid arthritis clinical practice guidelines based on published evidence and expert opinion | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
FDA Summary Review Otrexup | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Frequently Asked Questions on Prescription Drug User Fees | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Declaration of Maria Salgado | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Guidance for Industry Applications Covered by Section 505 | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Highlights of Prescribing Information OXTREXUP | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Highlights of Prescribing Information RASUVO | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Expert Declaration of Dr. Sean Nicholson | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Jefferies Boosts PT on Antares Pharma | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Methotrexate Fact Sheet | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Ashburn, Drug Repositioning Identifying and Developing New Uses for Existing Drugs | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Prescription Drug Trends | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Questions and Answers about Juvenile Arthritis | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Rheumatoid Arthritis Signs and Symptoms | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
State and County QuickFacts | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Goutsou, Biologics Utilization for Rheumatoid Arthritis in the United States An Observational Longitudinal Study | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Curtis | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Helmick, Estimates of the Prevalence of Arthritis and Other Rheumatic Conditions in the United States | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Kalb, Methotrexate and Psoriasis 2009 National Psoriasis Foundation Consensus Conference | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Kurd, The Prevalence of Previously Diagnosed and Undiagnosed Psoriasis in US Adults | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Juvenile Idiopathic Arthritis | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
MTX Information with Strength | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Memorandum Report Comparison of First-Quarter 2012 Average Sales Prices | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Psoriasis Treatments with Next Generation Vitamin D Analogs | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Augustin, Adherence in the Treatment of Psoriasis A Systematic Review | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Van den Bemt, Medication Adherence in Patients With Rheumatoid Arthritis A Critical Appraisal of the Existing Literature | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Beyer, Recent Trends in Systemic Psoriasis Treatment Costs | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
FDA Orange Book Data File Patent.txt | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
FDA Orange Book Data File Products.txt | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
FDA Orange Book Data File Exclusivity.txt | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Gowdie, Review of Disease Modifying Anti Rheumatic Drugs in Paediatric Rheumatic Disease | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Compilation of Drug Labels | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Greenapple, Trends in Biologic Therapies for Rheumatoid Arthritis: Results from a Survey of Payers and Providers | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Striesow | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Expert Declaration of Dr. Thomas M. Zizic | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Expert Declaration of Dr. John Clark | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Gaze | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Menter, Guidelines of Care for the Management of Psoriasis and Psoriatic Arthritis | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Dorr, Antidotes to Vesicant Chemotherapy Extravasations | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Schulmeister, Extravasation Management Clinical Update | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Methotrexate 100 mg/ml Injection | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Mount, Rheumatoid Arthritis Market | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Paul, How to Improve R and D Productivity | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Rachakonda, Psoriasis Prevalence Among Adults in the United States | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Smith, Systemic Therapy of Psoriasis Using Methotrexate | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Steinwachs, Pharmacy Benefit Plans and Prescription Drug Spending | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Malani, The Regulations of Medical Products | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Ignoffo | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Michaud, Direct Medical Costs and Their Predictors in Patients with Rheumatoid Arthritis | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Saag, American College of Rheumatology 2008 | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
DiMasi, R and D Costs and Returns to New Drug Development | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Eisenberg, Patents and Regulatory Exclusivity | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Stoller, Use of Plasma Pharmacokinetics to Predict and Prevent Methotrexate Toxicity | Jun 9, 2017 | EXHIBIT | PATENT OWNER |
Patent Owners Response | Jun 9, 2017 | PAPER | PATENT OWNER |
Order Granting Petitioner's Motion to Withdraw Counsel | Apr 26, 2017 | PAPER | BOARD |
Petitioner's Motion to Withdraw Counsel | Apr 19, 2017 | PAPER | PETITIONER |
Order Granting Patent Owner¿¿¿s Motion to Withdraw Counsel | Apr 14, 2017 | PAPER | BOARD |
Joint Stipulation to Modify Due Dates 1 and 2 | Mar 16, 2017 | PAPER | PATENT OWNER |
Petitioner's Supplemental Mandatory Notice Information | Feb 13, 2017 | PAPER | PETITIONER |
Executed Power of Attorney | Feb 13, 2017 | PAPER | PETITIONER |
Certificate of Service_POA | Feb 13, 2017 | PAPER | PETITIONER |
Patent Owner's Motion to Withdraw Counsel | Feb 10, 2017 | PAPER | PATENT OWNER |
Patent Owners Supplemental Mandatory Notice Information | Feb 10, 2017 | PAPER | PATENT OWNER |
Trial Instituted Document | Feb 8, 2017 | PAPER | BOARD |
Scheduling Order | Feb 8, 2017 | PAPER | BOARD |
Patent Owners Supplemental Mandatory Notice | Dec 23, 2016 | PAPER | PATENT OWNER |
Patent Owner's Preliminary Response | Nov 10, 2016 | PAPER | PATENT OWNER |
Breslin, et al., Improving Tolerance and Bioavailability of
Methotrexate by Switching from Oral to Subcutaneous Route of
Administration | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Balis, et al., Pharmacokinetics of Subcutaneous Methotrexate | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Antares Pharma Press Release, Antares Pharma Announces the
Publication of a Head-to-Head, Randomized, Crossover Study of Oral
versus Subcutaneous Methotrexate in Patients with Rheumatoid
Arthritis | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
RA Advisory Council: Overview & Meeting Objectives, October 5, 2012 | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Kurnick D. et al., Bioavailability of oral vs. subcutaneous low-dose
methotrexate in patients with Crohn¿¿¿s disease | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Chapter 16: Human: Veterinary Technology Cross Over, Long Acting
Animal Health Drug Products | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Chapter 3: Drug Administration, Drug Therapy In Nursing
Aschenbrenner DS and Venable SJ | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Consulting Agreement between Medac Pharma, Inc. and Dr. Michael Schiff, M.D | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Koios Pharmaceuticals LLC Press Release, Koios Pharmaceuticals Files Challenge to High-Cost Drug¿¿¿s Patent | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Declaration of Brian Gummow | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Declaration of Terri Shoemaker | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
U.S. Patent 8,480,631 | Nov 10, 2016 | EXHIBIT | PATENT OWNER |
Errata | Aug 18, 2016 | PAPER | BOARD |
Notice of Accepting Corrected Petition | Aug 12, 2016 | PAPER | BOARD |
Petitioner's Reply to Notice of Filing Date Accorded | Aug 11, 2016 | PAPER | PETITIONER |
Petitioner's Second Updated exhibit list | Aug 11, 2016 | PAPER | PETITIONER |
Notice of Accord Filing Date | Aug 10, 2016 | PAPER | BOARD |
Patent Owner Mandatory Notice | Aug 4, 2016 | PAPER | PATENT OWNER |
Power of Attorney | Aug 4, 2016 | PAPER | PATENT OWNER |
Ex. 1001--US8664231 | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1003--US6544504 | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1004--Hoekstra | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1014--Pincus | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1015--Insulin Admin | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1019--Schiff 2014 | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1002--Prosecution History Excerpts | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1005--Jorgensen | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1006--Alsufyani | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1008--Brooks | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1010--Zackheim | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1011--Muller-Ladner | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1017--EPO prosecution | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1018--Weinblatt 1993 | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1020--Weinblatt 1995 | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1023--Arthur_et_al-2002-Journal_of_Clinical_Nursing_parenteralmtx | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1024--J Rheumatol-2001-Arthur-212 | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1025--Rheumatology-2005-Moitra-256-7 | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1027--Feagan | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1028--Furst | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1029--Giannini | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1009-Medac Patent Owner Preliminary Response to Frontier IPR | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1012--Weinblatt Decl | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1013--Gammon Decl | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1026--Bigmar | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1007--Massarotti Decl. ISO Medac POPR to Frontier IPR | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1016-- Complaint in Medac v Antares | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1022--PDR for Wyeth | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1032--BSA Calculation | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1034--Schiff Declaration REDACTED | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1031--FDA Arthritis Advisory Committee | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1033--Miller Declaration | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1034--Schiff Declaration UNREDACTED | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1035--Noroozi Declaration | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1036--Kamholz Declaration | Jul 20, 2016 | EXHIBIT | PETITIONER |
Ex. 1021--Wyeth | Jul 20, 2016 | EXHIBIT | PETITIONER |
Petition for Inter Partes Review of Patent 8,664,231 | Jul 20, 2016 | PAPER | PETITIONER |
Petitioner's Power of Attorney | Jul 20, 2016 | PAPER | PETITIONER |
Petitioner's Updated Exhibit List | Jul 20, 2016 | PAPER | PETITIONER |
Ex. 1037--Second Kamholz Declaration | Jul 20, 2016 | EXHIBIT | PETITIONER |