Decision Denying Institution of Inter Partes Review | Apr 16, 2019 | PAPER | BOARD |
Petitioner's Updated Mandatory Notices | Jan 31, 2019 | PAPER | PETITIONER |
Petitioner's Updated Power of Attorney | Jan 31, 2019 | PAPER | PETITIONER |
Ex. 2102 - Ellis - Porcine Circovirus: A Historical Perspective | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Exhibit 2106 - Excerpts of Prosecution History of U.S. Patent No. 8,025,888 | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2109 - Jestin et al., U.S. Patent No. 7,223,594 | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Patent Owner Preliminary Response | Jan 24, 2019 | PAPER | PATENT OWNER |
Ex. 2101 - Allan - Novel porcine circoviruses from pigs with wasting
disease syndromes | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2103 - Tucker - Porcine multi-systemic wasting syndrome
(PMWS) a review | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2104 - Ramshaw - The prime-boost strategy: exciting prospects for
improved vaccination | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2105 - Excerpt of Prosecution History of U.S. Patent Application No. 13/190,452 | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2107 - Excerpts of Prosecution History of U.S. Patent No. 7,700,285 | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2108 - Excerpts of Prosecution History of U.S. Patent No. 7,833,707 | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2114 - Siebel - Part 2. Global experience from the field around one-shot vaccination | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2115 - Desrosiers - Preliminary results with Ingelvac CircoFLEX to protect multiple ages of Quebec pigs against PCVAD | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2110 - Jestin et al., U.S. Patent No. 7,223,407 | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2111 - Jestin et al., U.S. Patent No. 7,951,907 | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2112 - Petition for Inter Partes Review of U.S. Patent No. 9,011,872 in IPR2018-01788
(Sept. 24, 2018) | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2113 - Patent Owner¿¿¿s Preliminary Response to the Petition in IPR2018-00919 (July 24, 2018). | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2116 - Chevez - Long-term analysis of PCV2 prevalence in a Mexican herd using Ingelvac CircoFLEX | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Ex. 2117 - M. Fenaux - Immunogenicity and Pathogenicity of Chimeric Infectious DNA Clones of Pathogenic Porcine Circovirus Type 2 (PCV2) and Nonpathogenic PCV1 in Weanling Pigs | Jan 24, 2019 | EXHIBIT | PATENT OWNER |
Notice of Accord Filing Date | Oct 22, 2018 | PAPER | BOARD |
Patent Owner's Power of Attorney | Oct 15, 2018 | PAPER | PATENT OWNER |
Patent Owner Boehringer Ingelheim Vetmedica, Inc.'s Mandatory Notices Pursuant to 37 C.F.R. 42.8(a)(2) | Oct 15, 2018 | PAPER | PATENT OWNER |
Petitioner's Power of Attorney | Sep 24, 2018 | PAPER | PETITIONER |
Complaint in Boehringer Ingelheim Vetmedica, Inc. v. Merck & Co., Inc. and Intervet Inc. a/k/a Merck Animal Health, Case No. 2:18-cv-09534-JMV-JBC (D.N.J. May 21, 2018) (ECF No. 1) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Prosecution History of U.S. Patent No. 9,011,872 - Part 1 | Sep 24, 2018 | EXHIBIT | PETITIONER |
Eichmeyer et al., U.S. Patent No. 9,011,872 ("the '872 Patent") | Sep 24, 2018 | EXHIBIT | PETITIONER |
Prosecution History of U.S. Patent No. 9,011,872 - Part 3 | Sep 24, 2018 | EXHIBIT | PETITIONER |
Meng et al., International Publication No. WO 2003/049703 (¿¿¿Meng¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
M. Fenaux, T., et al., A Chimeric Porcine Circovirus (PCV), etc., 78 J.VIROL. 6297 (2004) (¿¿¿Fenaux¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Prosecution History of U.S. Patent No. 9,011,872 - Part 2 | Sep 24, 2018 | EXHIBIT | PETITIONER |
Jestin et al., U.S. Patent No. 6,703,023 ("Jestin") | Sep 24, 2018 | EXHIBIT | PETITIONER |
Blanchard et al., ¿¿¿Protection of swine against post-weaning multisystemic wasting syndrome (PMWS) by porcine circovirus type 2 (PCV-2) proteins,¿¿¿ VACCINE 21:4565-4575 (2003) (¿¿¿Blanchard¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Merial, Inc.¿¿¿s Petition for Inter Partes Review of US Patent No. 8,008,001 Under 35 U.S.C. ¿¿¿¿ 311-319 and 37 C.F.R. ¿¿ 42.1-.80 & 42.100-.123 | Sep 24, 2018 | EXHIBIT | PETITIONER |
Declaration of Merrill L. Schaeffer, Ph.D. and enclosures | Sep 24, 2018 | EXHIBIT | PETITIONER |
Declaration of Darin Madson, D.V.M., Ph.D. | Sep 24, 2018 | EXHIBIT | PETITIONER |
Parisot et al., International Publication No. WO 2005/009462 A2 (February 3, 2005) (¿¿¿Parisot¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
D. Mahe, et al., Differential recognition of ORF2 protein from type 1 and type 2 porcine circoviruses and identification of immunorelevant epitopes, 81 J. VIROL. 1815 (2000) (¿¿¿Mahe¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
M. Fort, A. Olvera, M. Sibila, J. Segal¿¿s & E. Mateu, Direction of Neutralizing Antibodies in Postweaning Multisystemic Wasting Syndrome (PMWS)-Affected and Non-PMWS-Affected Pigs, Veterinary Microbiology 125, 244-255 (2007) (¿¿¿Fort¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
G. Sala, et al., Development of Monocolonal Antibodies Based on ELISAs for the Detection of Antibodies, etc., The 5th International Congress of Veterinary Virology, Veterinary Virology in the New Millennium (2000) (¿¿¿Sala¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
L. Truchan, R. Jolie, P. Runnels, & D. McGavin, Eighteen Week Duration of Immunity in Pigs Vaccinated at 3 or 8 Weeks of Age with One Dose of a Mycoplasma hyopneumoniae Bacterin, American Association of Swine Practitioners (2000) (¿¿¿Truchan¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
John C.S. Harding & Edward G. Clark, Recognizing and diagnosing postweaning multisystemic wasting syndrome (PMWS), 5 SWINE HEALTH AND PRODUCTION 201 (1997) (¿¿¿Harding 1997¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
G. M. Allan, et al., Isolation of porcine circovirus-like viruses from pigs with a wasting disease in the USA and Europe, 10 J. VET. DIAGN INVEST 3 (1998) (¿¿¿Allan 1998¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
John C.S. Harding, The clinical expression and emergence of porcine circovirus 2, 98 VET. MICROBIOL. 131 (2004) (¿¿¿Harding 2004¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Joaquim Segales, Gordon M. Allan & Mariano Domingo, Porcine circovirus diseases, 6 ANIMAL HEALTH RES. REV. 119 (2005) (¿¿¿Segal¿¿s¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Roman M. Pogranichniy, Kyoung-Jin Yoon, Perry A. Harms, Sabrina L. Swenson, Jeffrey J. Zimmerman & Steven D. Sorden, Characterization of immune response of young pigs to porcine circovirus type 2 infection, 13 VIRAL IMMUNOL. 143 (2000) (¿¿¿Pogranichnyy¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
A. Mankertz., J. Mankertz, K. Wolf & H.J. Buhk, Identification of a protein essential for replication of porcine circovirus, 79 J.GEN.VIROL. 381 (1998) (¿¿¿Mankertz 1998¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
I. Brunborg, et al., Quantitation of porcine circovirus type 2 isolated from serum/plasma and tissue samples of healthy pigs and pigs with postweaning multisystemic wasting syndrome, etc., 122 J. VIROLOGICAL METHODS 171 (2004) (¿¿¿Brunborg¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Patrick Halbur & Tanja Opriessnig, Update on Porcine Circovirus Type 2 (PCV2)-Associated Diseases, VET. DIAGN. PRODUCTION ANIMAL MED. (¿¿¿Halbur¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Bublot et al., U.S. Patent No. 6,497,883 (¿¿¿Bublot¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Fenaux et al., ¿¿¿Genetic Characterization of Type 2 Porcine Circovirus (PCV-2), etc.,¿¿¿ Journal of Clinical Microbiology, 38:2494-2503 (2000) (¿¿¿Fenaux 2000¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
G. Reynaud, S. B¿¿s¿¿me, A. Brun, C. Charreyre, S. Desgouilles, P. Jeannin & S. Rehbein, Safety of a High Dose Administration of an Inactivated Adjuvanted PCV2 Vaccine in Conventional Gilts, 1 PROCEEDINGS OF THE 18TH IPVS CONGRESS 87 (2004) (¿¿¿Reynaud¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Declaration of Christopher C. L. Chase | Sep 24, 2018 | EXHIBIT | PETITIONER |
Porntippa Nawagitgul, Igor Morozov, Steven R. Bolin, Perry A. Harms, Steven D. Sorden & Prem S. Paul, Open reading frame 2 of porcine circovirus type 2 encodes a major capsid protein, 81 J.GEN.VIROL. 2281 (2000) (¿¿¿Nawagitgul¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
H. Jorio, R. Tran & A. Kamen, Stability of Serum-Free and Purified Baculovirus Stocks Under Various Storage Conditions, Biotechnol Prog. 22, 319-325 (2006) (¿¿¿Jorio¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Y. Okuda, et al., Experimental Reproduction of Postweaning Multisystem Wasting Syndrome in Cesaren-deprived, Colostrum-deprived Piglets Inoculated with Porcine Circovirus Type 2 (PCV2), etc., 15 J. Vet. Diag. Invest 107-114 (2003) (¿¿¿Shibata¿¿¿). | Sep 24, 2018 | EXHIBIT | PETITIONER |
Monique M. van Oers, Vaccines for Viral and Parasitic Diseases Produced with Baculovirus Vectors, 68 ADVANCES VIRUS RES. 193 (2006) (¿¿¿van Oers¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
M. Roof, K. Burkhart, and F. Zuckermann, Evaluation of the Immune Response and Efficacy of 1 and 2 dose commercial Mycoplasma hyopneumoniae bacterins, AMERICAN ASSOCIATION OF SWINE VETERINARIANS (2000) (¿¿¿Roof¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
A. Dawson, R. E. Harvey, S. J. Thevasagayam, J. Sherington, A. R. Peters, Studies of the Field Efficacy and Safety of a Single-Dose Mycoplasma hyopneumoniae Vaccine for Pigs, THE VETERINARY RECORD (Nov. 2, 2002) (¿¿¿Dawson¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Haemophilus Parasuis Bacterin Ingelvac HP-1 Product Label, Boehringer Ingelheim Vetmedica, Inc. | Sep 24, 2018 | EXHIBIT | PETITIONER |
Product News, NATIONAL HOG FARMER (Dec. 15, 2003). | Sep 24, 2018 | EXHIBIT | PETITIONER |
New Mycoplasma Vaccine Offers Convenience, Effective Protection, HIGH PLAINS/MIDWEST AG JOURNAL, (Feb. 14, 2005) http://www.hpj.com/archives/new-mycoplasma-vaccine-offers-convenience-effective-protection/article_aab328d5-1df1-590e-aed8-bc11330a46eb.html. | Sep 24, 2018 | EXHIBIT | PETITIONER |
Erysipelothrix Rhusiopathiae-Haemophilus Parasuis Vaccine and Methods of Using the Same, International Publication No. WO 2005/041890 A2 | Sep 24, 2018 | EXHIBIT | PETITIONER |
M. Kiupel, G.W. Stevenson, S.K. Mittal, E.G. Clark & D.M. Haines, Circovirus-like Viral Associated Disease in Weaned Pigs in Indiana, 35 VET. PATHOL. 303 (1998) (¿¿¿Kiupel¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Yuna Kim, Jinhyun Kim, Kyoungsoo Kang & Young S. Lyoo, Characterization of the Recombinant Proteins of Porcine Circovirus Type2 Field Isolate Expressed in the Baculovirus System, 3 J. VET. SCI. 19 (2002) (¿¿¿Kim¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Annette Mankertz & Bernd Hillenbrand, Replication of porcine circovirus type 1 requires two proteins encoded by the viral rep gene, 279 VIROLOGY 429 (2001) (¿¿¿Mankertz 2001¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
F. McNeilly, I. McNair, D. P. Mackie, B. M. Meehan, S. Kennedy1 D. Moffett, J. Ellis, S. Krakowka & G. M. Allan, Production, characterisation and applications of monoclonal antibodies to porcine circovirus 2, 146 ARCH VIROL 909 (2001) (¿¿¿McNeilly¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Gordon M. Allan & John A. Ellis, Porcine circoviruses: a review, 12 J. VET. DIAGN. INVEST. 3 (2000) (¿¿¿Allan 2000¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
P. Rueda, J. Fominaya, J. Langeveld, C. Bruschke, C. Vela, & J. Casal, Effect of Different Baculovirus Inactivation Procedures on the Integrity and Immunogenicity of Porcine Parvovirus-like Particles, 19 Vaccine 726-734 (2001) (¿¿¿Rueda¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
J. Carr & Garth Veterinary Group, Garth Pig Stockmanship Standards, THE PIG SITE, (Sept. 14, 2018, 2:45 p.m.) http://www.thepigsite.com/stockstds/17/growth-rate/. (¿¿¿Carr¿¿¿). | Sep 24, 2018 | EXHIBIT | PETITIONER |
P. Offit & R. Jew, Adressing Parents¿¿¿ Concerns: Do Vaccines Contain Harmful Preservatives, Adjuvants, Additives, or Residuals? 112 Pediatrics 6 (December 2003) (¿¿¿Offit¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
M. Kuhn, Comparative Safety Evaluation of a One-dose M.hyopneumoniae bacterin (¿¿¿RespiSure-One) and a Competitor One-dose M. hyopneumoniae bacterin, Pfizer Animal Health Swine Veterinary Services (¿¿¿Respisure One¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
SIV Vaccine, dvm360 (Mar. 1, 2004), http://veterinarynews.dvm360.com/siv-vaccine | Sep 24, 2018 | EXHIBIT | PETITIONER |
European Patent No. EP2281829 | Sep 24, 2018 | EXHIBIT | PETITIONER |
Application No. 10174465.4 Information regarding oral proceedings of 12.09.18 | Sep 24, 2018 | EXHIBIT | PETITIONER |
Chanhee Chae, Commercial porcine circovirus type 2 vaccines: Efficacy and clinical application, 194 Vet. J. 151 (2012) (¿¿¿Chae¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
Ellis et al., U.S. Patent No. 6,517,843 (¿¿¿Ellis¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
M. Mombarg, Is One More Than Two?, 34 IPVS Health Pig International 3 (March 2004) (¿¿¿Mombarg¿¿¿) | Sep 24, 2018 | EXHIBIT | PETITIONER |
P.C. Liao, Y.L. Lin, M.H. Jong, & W.B. Chung, Efficacy of Foot-and-Mouth Disease Vaccine in Pigs with Single Dose Immunization, 21 Vaccine 1807-1810 (2003) ("Liao") | Sep 24, 2018 | EXHIBIT | PETITIONER |
R. Moorman, A. Bouma, J. Kramps, C. Terpstra, H. De Smit, Development of a Classical Swine Fever Subunit Marker Vaccine and Companion Diagnostic Test ("Moorman") | Sep 24, 2018 | EXHIBIT | PETITIONER |
B. Bosworth, Evaluation of a One-dose Mycoplasma hyopneumoniae Bacterin and a One-dose Erysipelas Rhusiopathie Bacterin, American Association of Swine Veterinarians (2004) ("Pneumonostar Myco _ Panstar Ery") | Sep 24, 2018 | EXHIBIT | PETITIONER |
M. Hammer, B. Bosworth, D. Stine, E. Springer, T. Johnson, Evaluation of One-Dose MycoPlasma hyopneumoniae bacterin (PneumoSTAR Myco) at 23 Weeks Post Vaccination, American Association of Swine Veterinarians (2005) | Sep 24, 2018 | EXHIBIT | PETITIONER |
D. Nilubol, et al., The Effect of a Killed Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), etc. 102 VETERINARY MICROBIOLOGY 11-18 (2004) ("Nilubol") | Sep 24, 2018 | EXHIBIT | PETITIONER |
S.J. Barteling & J. Vreeswijk, Developments in Foot-and-Mouth Disease Vaccines, 9 VACCINE 75-86 (Feb. 1991) ("Barteling") | Sep 24, 2018 | EXHIBIT | PETITIONER |
J. Srinivasappa, I. Morozou, M. Gill, & H. Chu, Efficacy, Safety and Serological Cross-Reactivity of Fort Dodge Animal Health's Swine Influenza Vaccine, American Association of Swine Veterinarians (2003) ("Srinivasappa") | Sep 24, 2018 | EXHIBIT | PETITIONER |
H. Bahnemann, Inactivation of Viral Antigens for Vaccine Preparation with Particular Reference to the Application of Binary Ethylenimine, 8 VACCINE 299-303 (1990) ("Bahnemann") | Sep 24, 2018 | EXHIBIT | PETITIONER |
C. Charreyre, S. BESEME, L. Boeuf-Teseschi, M. Bublot, & G. Reynaud, Protection Against PCV2 Experimental Challenge in 3 Week-Old Piglets by Maternal Antibodies, Proceedings of the 17th IPVS Congress, Ames, Iowa, USA (2002) ("Charreyre") | Sep 24, 2018 | EXHIBIT | PETITIONER |
Declaration of Dr. Phil Hayes ("Hayes Declaration") | Sep 24, 2018 | EXHIBIT | PETITIONER |
Declaration of Sylvia D. Hall-Ellis, Ph.D. | Sep 24, 2018 | EXHIBIT | PETITIONER |
Petition for Inter Partes Review of U.S. Patent No. 9,011,872 | Sep 24, 2018 | PAPER | PETITIONER |
W.L. Mengeling, T.T. Brown, P.S. Paul, & D.E. Gutekunst, Efficacy of an Inactive Virus Vaccine for Prevention of Porcine Parvovirus-Induced Reproductive Failure¿¿40 AM. J. VET. RES. 2 (Feb. 1979) ("Mengeling") | Sep 24, 2018 | EXHIBIT | PETITIONER |
F. Brown, Inactivation of Viruses by Aziridines, 20 VACCINE 322-327 (2002) ("Brown") | Sep 24, 2018 | EXHIBIT | PETITIONER |
P.A. Harms, et al., Experimental Reproduction of Severe Disease in CD/CD Pigs Concurrently Infected with Type 2 Porcine Circovirus and PRRSV, 38 VET. PATHOL. 528-539 (2001) ("Harms") | Sep 24, 2018 | EXHIBIT | PETITIONER |
K. Diehl, et al., A Good Practice Guide to the Administration of Substances and Removal of Blood, Including Routes and Volumes, 21 J. APPL. TOXICOL. 15-23 (2001) ("Deihl") | Sep 24, 2018 | EXHIBIT | PETITIONER |
M.M. Hulst, D.F. Westra, G. Wensvoort, & R.J.M. Moormann, Glycoprotein E1 of Hog Cholera Virus Expressed in Insect Cells Protects Swine from Hog Cholera, 67 J. VIROLOGY 9:5435-5442 (Sept. 1993) ("Hulst") | Sep 24, 2018 | EXHIBIT | PETITIONER |