Notice of Refund | Aug 7, 2019 | PAPER | BOARD |
Petitioner's Request for Refund of Post-Institution Fees | Jul 23, 2019 | PAPER | PETITIONER |
Trial Instituted Document | May 31, 2019 | PAPER | BOARD |
Amended Joint Claim Construction and Prehearing Statement | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Bracco's Responses to Invalidity Contentions | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Bracco's Opening Markman Brief | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Bracco's Expert Declaration Concerning Markman Brief | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Maia's Expert Declaration Concerning Markman Brief | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
US Patent No. 5,574,136 | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
US Patent Application Publication No. 2019/0060240 | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Original (as filed) claims of US2019/0060240 | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Response to Office Action filed Feb. 19, 2019, in US2019/0060240 | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Patent Owner's Preliminary Response | Mar 4, 2019 | PAPER | PATENT OWNER |
Citizen Petition | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Maia Invalidity Contentions | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Maia Opening Markman Brief | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
U.S. Provisional Patent Application No. 62/550,484 | Mar 4, 2019 | EXHIBIT | PATENT OWNER |
Patent Owner's Submission of Updated Mandatory Notice Information | Feb 19, 2019 | PAPER | PATENT OWNER |
Patent Owner's Updated Power Of Attorney | Feb 19, 2019 | PAPER | PATENT OWNER |
Patent Owner's Submission of Mandatory Notice Information | Dec 10, 2018 | PAPER | PATENT OWNER |
Patent Owner's Submission of Mandatory Notice Information | Dec 10, 2018 | PAPER | PATENT OWNER |
Patent Owner's Power of Attorney | Dec 10, 2018 | PAPER | PATENT OWNER |
Notice of Accord Filing Date | Dec 4, 2018 | PAPER | BOARD |
Petition | Nov 19, 2018 | PAPER | PETITIONER |
Prosecution History excerpts for the 046 patent | Nov 19, 2018 | EXHIBIT | PETITIONER |
CV of Christian Schoneich, Ph.D. | Nov 19, 2018 | EXHIBIT | PETITIONER |
Petitioner Power of Attorney | Nov 19, 2018 | PAPER | PETITIONER |
U.S. Patent No. 6,803,046 to Metcalfe et al. | Nov 19, 2018 | EXHIBIT | PETITIONER |
Declaration of Christian Schoneich, Ph.D. | Nov 19, 2018 | EXHIBIT | PETITIONER |
Bacarese-Hamilton et al., Oxidation/Reduction of Methionine Residues in CCK: A Study by Radioimmunoassay and Isocratic Reverse Phase High Pressure Liquid Chromatography, 6 Peptides 17 (1985) | Nov 19, 2018 | EXHIBIT | PETITIONER |
U.S. Patent No. 7,329,644 to Saviano et al. | Nov 19, 2018 | EXHIBIT | PETITIONER |
Akers et al., Peptides and Proteins as Parenteral Solutions, in Pharmaceutical Formulation Development of Peptides and Proteins (2000) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Wang et al., Review of Excipients and pHs for Parenteral Products Used in the United States, 34 PDA J. Pharm. Sci and Tech. 452 (1980) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Nema et al., Excipients and Their Use in Injectable Products, 51 PDA J. of Pharma. Sci. and Tech. 166 (1997) | Nov 19, 2018 | EXHIBIT | PETITIONER |
U.S. Patent Publication No. 2003/0104996 to Li et al. | Nov 19, 2018 | EXHIBIT | PETITIONER |
Physicians Desk Reference For Radiology and Nuclear Medicine, 1977/78 (1977) (PDR) | Nov 19, 2018 | EXHIBIT | PETITIONER |
PCT Publication No. WO 00/5169 to Sato | Nov 19, 2018 | EXHIBIT | PETITIONER |
PCT Publication No. WO 00/5169 to Sato (English Translation with affidavit) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Bacarese-Hamilton et al., Prevention of Cholecystokinin Oxidation During Tissue Extraction, 448 Neuronal Cholecystokinin 571 (1985) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Rational Design of Stable Protein Formulations: Theory and Practice, Chapters 5 & 8 (Carpenter and Manning, ed., April 30, 2002) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Liddle, R. A., On the Measurement of Cholecystokinin, 44 Clinical Chemistry 5 (1998) | Nov 19, 2018 | EXHIBIT | PETITIONER |
DeLuca, et al., Formulation of Small Volume Parenterals, in Pharmaceutical Dosage Forms: Parenteral Medications Volume 1 (1992) | Nov 19, 2018 | EXHIBIT | PETITIONER |
U.S. Patent No. 3,937,819 to Ondetti et al. | Nov 19, 2018 | EXHIBIT | PETITIONER |
Wunsch, E., Peptide Factors as Pharmaceuticals: Criteria for Application, 22 Biopolymers 493 (1983) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Yagami, et al., Stabilization of a tyrosine O-sulfate residue by a cationic functional group: , 56 J. Peptide Res. 239 (2000) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Huttner, W. B., Determination and Occurrence of Tyrosine O-Sulfate in Proteins, 107 Methods in Enzymology 200 (1984) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Moroder et al., Gastrin and Cholecystokinin, An Arduous Task for the Peptide Chemist in Natural Product Chemistry (1986) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Package Insert for KINEVAC Sincalide for Injection, November 1994 | Nov 19, 2018 | EXHIBIT | PETITIONER |
Uffelman, W., Unexpected Shortfalls of Two Nuclear Medicine Pharmaceuticals, 42 J. Nuc. Med. 16N (2001) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Handbook of Pharmaceutical Excipients, Third Edition, Arthur H. Kibbe, Ed. (2000) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Jensen et al., Metal-Catalyzed Oxidation of Brain-Derived Neurotrophic Factor (BDNF) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Wang et al., Parenteral Formulations of Proteins and Peptides: Stabilities and stabilizers, 42 J. Parenteral Sci. and Tech. S4 (1988) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Yoshioka, et al., Stability of Peptide and Protein Pharmaceuticals in Stability of Drugs and Dosage Forms (2002) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Marseigne, et al., Full Agonists of CCK8 Containing a Nonhydrolyzable Sulfated Tyrosine Residue, 32 J. Med. Chem. 445 (1989) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Gorman et al., Proton Affinities of the 20 Common -Amino Acids, 114 J. Am. Chem. Soc. 3986 (1992) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Liddle, R. A., Cholecystokinin Cells, 59 Annu. Rev. Physiol. 221 (1997) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Wang, Y.J., Parenteral Products of Peptides and Proteins, in Pharmaceutical Dosage Forms: Parenteral Medications Volume 1 (1992) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Essentials of Nuclear Medicine Science (Hladik, et al., eds., 1987) | Nov 19, 2018 | EXHIBIT | PETITIONER |
U.S. Patent No. 5,272,135 to Takruri | Nov 19, 2018 | EXHIBIT | PETITIONER |
FDA Approval Package for NDA Application Number 017697-S012. | Nov 19, 2018 | EXHIBIT | PETITIONER |
Fendler et al., Hydrolysis of Nitrophenyl and Dinitrophenyl Sulfate Esters, 33 J. Org. Chem. 10 3852 (1968) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Jensen et al., Metal-Catalyzed Oxidation of Brain-Derived Neurotrophic Factor (BDNF): Selectivity and Conformational Consequences of Histidine Modification, (2000) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Swadesh, et al., Sodium Sulfite as an Antioxidant in the Acid Hydrolysis of Bovine Pancreatic Ribonuclease A, 141 Analytical Biochemistry 397 (1984) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Mattern et al., Formulation of Proteins in Vacuum-Dried Glasses. II. Process and Storage Stability in Sugar-Free Amino Acid Systems, | Nov 19, 2018 | EXHIBIT | PETITIONER |
Banga, A.K., Structure and Analysis of Therapeutic Peptides and Proteins (2006) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Wang et al., Lyophilization and Development of Solid Protein Particles, 203 Int. J. of Pharm. 1 (2000) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Bush et al., A critical evaluation of clinical trials in reactions to sulfites, 78 J. Allergy Clin. Immunol. 191 (1986) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Liddle, et al., Cholecystokinin Bioactivity in Human Plasma, 75 J. Clin. Invest. 1144 (1985) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Konturek, et al., Effect of Cholecystokinin Receptor Antagonist on Pancreatic Responses (1988) | Nov 19, 2018 | EXHIBIT | PETITIONER |
Graf, et. al., ¿¿¿Iron-catalyzed Hydroxyl Radical Formation,¿¿¿ 259 J. Bio. Chem. 3620 (1984) | Nov 19, 2018 | EXHIBIT | PETITIONER |
U.S. Patent No. 6,238,664 to Hellerbrand et al. | Nov 19, 2018 | EXHIBIT | PETITIONER |