BORAGEN, INC. vs Syngenta Participations AG et al.

Decision Denying Petitioner's Request on Rehearing of Decision Denying Institution of Inter Partes Review

IPR2020-00124 Request for Rehearing

Decision - Denying Institution of Inter Partes Review

IPR2020-00124 Petitioner Updated Mandatory Notice

IPR2020-00124 Petitioner Updated POA

PO Preliminary Response

Ex. 2001

Update Mandatory Notice for Patent Owner

Power of Attorney for Patent Owner

Updated Mandatory Notice for Patent Owner

Power of Attorney for Patent Owner

Errata

Power of Attorney for Patent Owner

Mandatory Notice for Patent Owner

Notice of Accord Filing Date

U.S. Patent No. 10,130,096 entitled ¿¿¿Method for Protecting Useful Plants or Plant Propagation Material¿¿¿ (the ¿¿¿¿¿¿096 patent¿¿¿)

WO 1995/33754 (¿¿¿Austin¿¿¿)

Seiradake E, et al., ¿¿¿Antifungal activity and mechanism of action of a benzoxaborole, AN2718, which is in development for the treatment of Tinea pedis,¿¿¿ Abstract F1-1176, IDSA Poster Session: New Anti-Fungal Agents (2008)

Mao W, et al., ¿¿¿AN2718 has broad spectrum antifungal activity necessary for the topical treatment of skin and nail fungal infections,¿¿¿ Abstract P2422, J. American Acad. Dermatology 60(3) Supplement 1, AB116 (2009)

Rolshausen PE, et al., ¿¿¿Use of boron for the control of Eutypa dieback of grapevines,¿¿¿ Plant Diseases 89(7): 734-738 (2005)

Qin G, et al., ¿¿¿Inhibitory effect of boron against Botrytis cinerea on table grapes and its possible mechanisms of action,¿¿¿ International Journal of Food Microbiology 138: 145-150 (2010)

Thomidis T and Exadaktylou E., ¿¿¿Effect of boron on the development of brown rot (Monilinia laxa) on peaches,¿¿¿ Crop Prot. 29: 572¿¿¿576 (2010)

U.S. Patent No. 3,686,398 (¿¿¿Kohn¿¿¿)

WO 2009/130481 (¿¿¿Sibley¿¿¿)

WO 2009/144473 (¿¿¿Birch¿¿¿)

U.S. Patent No. 7,582,621 (¿¿¿Baker¿¿¿)

U.S. Patent Pub. No. 2002/0165121 (¿¿¿Brehove¿¿¿)

WO 2003/009689 (¿¿¿Freeman¿¿¿)

Baker SJ, et al., ¿¿¿Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis.¿¿¿ J. Med. Chem. 49(15): 4447-4450 (2006) (¿¿¿Baker 2006¿¿¿)

Baker SJ, et al., ¿¿¿Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis.¿¿¿ J. Med. Chem. 49(15): 4447-4450 (2006) (¿¿¿Baker 2006¿¿¿)

Expert Declaration of Phillip M. Brannen, Ph.D.

Boric Acid, Chemical Watch Factsheet, 21, 18-19 (2001)

Ligon JM, et al, ¿¿¿Natural products with antifungal activity from Pseudomonas biocontrol bacteria,¿¿¿ Pest Management Science 56: 688-695 (2000)

Alumni Product Registration (June 9, 2010)

Propi-Shield Product Registration (August 11, 2005)

Tilt Label (2006)

Mahmoud YAG, et al., ¿¿¿Recent approaches for controlling brown spot disease of faba bean in Egypt,¿¿¿ Egypt Acad. J. Biol. Sci. 3: 41¿¿¿53 (2011)

Ware G, ¿¿¿Substituted aromatics,¿¿¿ pages 148-149, In: Fundamentals of Pesticides: a self-instruction guide, Tomson Publications, Fresno, CA (1991)

Bertelsen JR, et al., ¿¿¿Fungicidal effects of azoxystrobin and epoxiconazole on phyllosphere fungi, senescence and yield of winter wheat,¿¿¿ Plant Pathology 50: 190-205 (2001)

Propi-Shield Label Amendment (November 29, 2006)

Azotech Label Amendment (September 7, 2007)

optiSHIELD Label (2009)

Abound label (2007)

Chlorosel label (2010)

Ultrex label (2005)

Chloroneb Fact Sheet (2005)

Dichloran Label Amendment (August 5, 2010)

Expert Declaration of Dennis Hall, Ph.D.

PubChem entry for AN2718

Part 1-File History for the ¿¿¿096 patent

Part 2-File History for the ¿¿¿096 patent

Rock FL, et al., ¿¿¿An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site,¿¿¿ Science 316: 1759-1761 (2007)

PETITIONER¿¿¿S POWER OF ATTORNEY

PETITION FOR INTER PARTES REVIEW OF U.S. PATENT NO. 10,130,096