Liquidia Technolgies, Inc. vs United Therapeutics Corp.

Other: Fed Circuit mandate

Other: other court decision

Petitioner's Notice of Cross-Appeal

Patent Owner's Notice of Appeal

Patent Owner's Notice of Appeal

Rehearing:Decision on Request for Rehearing

Order: Order Denying POP Request

Ex. 3002 POP E-Mail Request

Notice: notice of receipt of POP request

Patent Owner's Request for Panel Rehearing

Final Written Decision: original

Exhibit 3001

Other: Hearing transcript

LEAP Practitioner Request and Verification Form

EX2037 Patent Owner Demonstratives

Petitioner's Updated Exhibit List

Ex 1056 - 2021-06-23_Liquidia 901 IPR Hearing Demonstratives

Patent Owner's Opposition to Petitioner's Motion to Submit Supplemental Information

Ex 2035 - Claim Construction Order

Petitioner's Updated Exhibit List

Petitioner's Demonstrative Exhibit

EX2036 - Patent Owner Demonstratives

Petitioner's Motion to Submit Supplemental Evidence

Transcript from June 4, 2021 - Markman Hearing in UTC v. Liquidia - No. 20-755-RGA-JLH (D.Del)

EXPUNGED

Petitioner's Updated Exhibit List

Patent Owner's Objections to Petitioner's Supplemental Evidence Submitted with Petitioner's Opposition to Patent Owner's Motion to Exclude

Patent Owner's Reply to Opposition to Motion to Exclude

ORDER Setting Oral Argument 37 C.F.R. sec 42.70

Patent Owner's Updated Mandatory Notices

Petitioner's Opposition to PO's Motion to Exclude

Petitioner's Updated Exhibit List

Japanese Pat. App. No. 56-122328A to Kawakami et al.

Certified English translation of Japanese Pat. App. No. 56-122328A to Kawakami et al.

Affidavit of Boris Levine certifying translation of Japanese Pat. App. No. 56-122328A

Declaration of James Dowdle

Declaration of Boris Levine

Supplemental Declaration of Sylvia Hall-Ellis Ph.D.

Patent Owner's Motion to Exclude

Joint Paper Concerning Petitioner's Request to Strike Portions of Patent Owner's Paper Nos. 12 and 25nand Exhibits 2002 and 2025

Petitioner's Updated Exhibit List

Highlighted Patent Owner's Response to Petition

Highlighted Declaration of Rodolfo Pinal, Ph.D. (Ex. 2002)

Highlighted Declaration of Rodolfo Pinel, Ph.D. Supporting UTC's Patent Owner Response (Ex. 2025)

Highlighted Patent Owner's Sur-Reply

Petitioner's Request for Oral Hearing

Patent Owner's Request for Oral Argument

ORDER Granting Petitioner's Unopposed Motion for Pro Hac Vice Admission of Deepa Kannappan

Patent Owner's Sur-Reply

Ex 2029: Linked-In Profile of Ken Phares

Ex 2030: Linked-In Profile of David Mottola

Ex 2031: Linked-In Profile of Bob Moriarty

Ex 2032: Second Winkler Deposition Transcript, April 5, 2021

Ex 2033: Supplemental Declaration of Robert R. Ruffolo, Ph.D., April 2, 2021 (United Therapeutics Co. v. Liquidia Techs., Inc., Case No. 1:20-cv-00755-RGA (D. Del.))

Ex 2034: Ruffolo Deposition Transcript, April 15, 2021 (United Therapeutics Co. v. Liquidia Techs., Inc., Case No. 1:20-cv-00755-RGA (D. Del.))

CORRECTED Ex 2033: Supplemental Declaration of Robert R. Ruffolo, Ph.D., April 2, 2021 (United Therapeutics Co. v. Liquidia Techs., Inc., Case No. 1:20-cv-00755-RGA (D. Del.))

Petitioner's Updated Mandatory Notice Regarding Additional Backup Counsel

Petitioner's Updated Power Of Attorney

Petitioner's Unopposed Motion for Pro Vac Vice Admission of Deepa Kannappan

Petitioner's Updated Exhibit List

Declaration of Deepa Kannappan ISO Motion for Pro Hac Vice

Biography of Deepa Kannanappa

Joint Stipulation to Extend Due Date 3 by One Week

Patent Owner's Updated Mandatory Notices

Patent Owner's Notice of Deposition of Jeffrey D. Winkler, Ph.D.

Petitioner's Updated Exhibt List

Signature page to Ex. 1018 Deposition transcript of Rodolfo Pinal, dated February 10, 2021

DECISION - Denying Patent Owners Request on Rehearing of Decision on Institution 37 C.F.R.42.71(d)

Petitioner's Response ISO Petition for Inter Partes Review

Petitioner's Updated Exhibit List

Reply Declaration of Jeffrey D. Winkler, Ph.D.

Deposition transcript of Rodolfo Pinal, dated February 10, 2021

Gao, K., ���Synthesis of A-Galceramides, (-)-Treprostinil, and Design and Synthesis of Anti-Viral Agents,��� Doctor Of Philosophy in Chemistry in the Graduate College of the University of Illinois at Chicago, 2006

Parks, B.W., et al., ���Convenient Synthesis of 6,6-Bicyclic Malonamides: A New Class of Conformationally Preorganized Ligands for f-Block Ion Binding,��� J. Org. Chem., 71:9622-27 (2006)

Hanessian, S., et al., ���Structure-Based Organic Synthesis of a Tricyclic N-Malayamycin Analogue,��� J. Org. Chem., 71:9807-17 (2006)

Frost, J.M., et al., ���Synthesis and Structure ��� Activity Relationships of 3,8-Diazabicyclo[4.2.0]octane Ligands, Potent Nicotinic Acetylcholine Receptor Agonists,��� J. Med. Chem., 49:7843-53 (2006)

Regan, J., et al., ���Quinol-4-ones as Steroid A-Ring Mimetics in Nonsteroidal Dissociated Glucocorticoid Agonists,��� J. Med. Chem., 49:7887-96 (2006)

Paulekuhn, G.S., et al., ���Trends in Active Pharmaceutical Ingredient Salt Selection based on Analysis of the Orange Book Database,��� J. Med. Chem., 50:6665-72 (2007)

Mak, K.K.W., et al., ���Mannich Reactions in Room Temperature Ionic Liquids (RTILs): An Advanced Undergraduate Project of Green Chemistry and Structural Elucidation,��� J. Chem. Ed., 83(6):943-46 (2006)

Supplemental Materials to Mak, K.K.W., et al., ���Mannich Reactions in Room Temperature Ionic Liquids (RTILs): An Advanced Undergraduate Project of Green Chemistry and Structural Elucidation,��� J. Chem. Ed., 83(6):943-46 (2006)

Baar, M.R., et al., ���Enantiomeric Resolution of (��)-Mandelic Acid by (1R,2S)-(���)-Ephedrine,��� J. Chem. Ed., 82(7):1040-42 (2005)

Supplemental Materials for Baar, M.R., et al., ���Enantiomeric Resolution of (��)-Mandelic Acid by (1R,2S)-(���)-Ephedrine,��� J. Chem. Ed., 82(7):1040-42 (2005)

Brigandi, L.M., et al., ���Synthesis and Analysis of Copper Hydroxy Double Salts,��� J. Chem. Educ., 82(11):1662 (2005)

Supplemental Material for Online Publication for Brigandi, L.M., et al., ���Synthesis and Analysis of Copper Hydroxy Double Salts,��� J. Chem. Educ., 82(11):1662 (2005)

Hamilton, ���Experiment #5: Resolution of (R,S)-1-Phenylethylamine via Diastereoisomer formation with (2R),(3R)-Tartaric Acid,��� Laboratory Manual for Chemistry 202, Organic Chemistry Laboratory I at Mount Holyoke College (2006)

Yadav, J.S., et al., ���A concise and stereoselective synthesis of both enantiomers of altholactone and isoaltholactone,��� Tetrahedron Letters, 44:5831-33 (2003)

Takadoi, M., et al., ���Synthetic studies of himbacine, a potent antagonist of the muscarinic M2 subtype receptor 1. Stereoselective total synthesis and antagonistic activity of enantiomeric pairs of himbacine etc., Tetrahedron 58 (2002) 9903���23

Berge, S.M., et al., ���Pharmaceutical Salts,��� J. Pharm. Scis., 66(1):1-19 (1977)

Excerpts from Loewenthal, H.J.E., et al., A Guide for the Perplexed Organic Experimentalist, Chapter 4: Running Small-scale Reactions in the Research Laboratory, pp. 87-119, 2d ed. (1990)

Heidelberger, M., An Advanced Laboratory Manual of Organize Chemistry (1928)

Product Information for Remodulin (2006)

Excerpt from Hawley���s Condensed Chemical Dictionary, 15th ed. (2007)

Refiled Declaration of Jeffrey D. Winkler, Ph.D. (Ex. 1002)

Petitioner's Notice of Taking Deposition of Rodolfo Pinal PhD

Ex. 2019, Levin, Pharmaceutical Process (2006)

Ex. 2022, Ahuja, et al., Assuring quality of drugs (2007)

Ex. 2023, Paul, et al., Design of Reaction Systems (1988)

Ex. 2025, Declaration of Rodolfo Pinal, Ph.D.

Ex. 2026, Winkler Deposition Transcript

Patent Owner's Response to Petition

Ex. 2017, Anderson, Practical Process Research (2012)

Ex. 2018, Gad, Pharmaceutical Manufacturing Handbook (2008)

Ex. 2020, Bennett, Pharmaceutical Production (2003)

Ex. 2021, Qiu, et al., Identification of pharmaceutical impurities

Ex. 2024, Wadekar, et al., Evaluating Impurities (2012)

Ex. 2027, U.S. Patent No. 9,593,066

Ex. 2028, Prosecution History of U.S. Patent Appl. No. 13/933,623

Patent Owner's Notice of Deposition of Jeffrey D. Winkler

Patent Owner's Objections to Petitioner's Evidence Submitted With Petition

Patent Owner's Request for Rehearing

Scheduling Order

Trial Instituted Document

Patent Owner Preliminary Response

21 C.F.R. ¿¿210.3 (April 1, 2007 edition)

Declaration of Rodolfo Pinal, Ph.D.

Curriculum Vitae of Rodolfo Pinal, Ph.D.

Office Action, U.S. Appl. Ser. No. 15/423,021 dated Jan. 11, 2018

Complete Prosecution History of U.S. Patent No. 9,604,901 (Part 2)

Complete Prosecution History of U.S. Patent No. 9,604,901 (Part 3)

Complete Prosecution History of U.S. Patent No. 9,604,901 (Part 7)

FDA Polymorph Guidance (2007)

Complete Prosecution History of U.S. Patent No. 9,604,901 (Part 1)

Complete Prosecution History of U.S. Patent No. 9,604,901 (Part 4)

Complete Prosecution History of U.S. Patent No. 9,604,901 (Part 5)

Complete Prosecution History of U.S. Patent No. 9,604,901 (Part 6)

Stahl, Handbook of Pharmaceutical Salts

Batra, Crystallization Process Development

Wiberg, Laboratory Technique

Schoffstall, Microscale and Miniscale

Comparing IPR2020-00770 EX1002 to the Petition in IPR2020-00770

Patent Owner's Updated Mandatory Notices

Patent Owner's Mandatory Notices Under 37 C.F.R. Sec. 42.8

Notice of Accord Filing Date

Ex 1002 901 IPR Petition_Winkler Declaration

Liquidia 901 IPR Petition

Liquidia Petitioner Power of Attorney - 901 Petition signed

Ex 1001 US9604901

Ex 1003 WinklerCVLegal-0320

Ex 1004 393 Patent

Ex 1007 117 Patent

Ex 1014 US4306075

Ex 1005 IPR2016-00006

Ex 1006 901 File History

Ex 1008 Phares WO2005007081

Ex 1009 Moriarty et al J Org Chem 2004 69 p. 1890-1902

Ex 1010 Wiberg

Ex 1011 Schoffstall

Ex 1012 Kawakami

Ex 1013 Ege

Ex 1015 901 Hall-Ellis declaration executed 3-25-2020

Ex 1016 393 File History