The detailed information for PTAB case with proceeding number IPR2021-00816 filed by Regeneron Pharmaceuticals, Inc. et al. against Novartis Pharma AG et al. on Apr 16, 2021. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Case Details

Proceeding Number
IPR2021-00816
Filing Date
Apr 16, 2021
Petitioner
Regeneron Pharmaceuticals, Inc. et al.
Respondent
Novartis Pharma AG et al.
Status
Final Written Decision
Respondent Application Number
13750352
Respondent Tech Center
3700
Respondent Patent Number
9220631
Institution Decision Date
Oct 26, 2021
Termination Date
Oct 25, 2022

Proceeding Documents

The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.


Document NameFiling DateCategoryFiling Party

Alert me when new update on this case

Other: other court decision

Jan 30, 2025PAPERBOARD

Other: Fed Circuit mandate

Nov 13, 2024PAPERBOARD

Other: other court judgment

Nov 13, 2024PAPERBOARD

EXPUNGED

Jan 24, 2023PAPERBOARD

Final Written Decision: original

Jan 24, 2023PAPERBOARD

Order: Order: Granting Joint Motion to Seal

Jan 24, 2023PAPERBOARD

Joint Motion to Seal the Final Written Decision

Jan 20, 2023PAPERPETITIONER

Redacted Final Written Decision

Jan 20, 2023EXHIBITPETITIONER

Patent Owner's Notice of Appeal

Dec 23, 2022PAPERPATENT OWNER

Order: Directing the Submission of a Redacted Public Version of the Final Written Decision and Granting the Joint Motion to Expunge Certain Exhibits - 37 CFR 42.5 and 42.14

Nov 1, 2022PAPERBOARD

Final Written Decision: Final Written Decision Determining All Challenged Claims Unpatentable 35 U.S.C. sec. 318a

Oct 25, 2022PAPERBOARD

Order: Dismissing Motion to Exclude as Moot 37 C.F.R. secs. 42.64c, 42.61a

Oct 25, 2022PAPERBOARD

Other: Hearing transcript

Sep 6, 2022PAPERBOARD

Joint Motion to Expunge

Aug 12, 2022PAPERPETITIONER

Patent Owner���s Reply in Support of its Motion to Exclude

Jul 18, 2022PAPERPATENT OWNER

Order: ORDER Granting Petitioners Motion to Seal 37 C.F.R. §§ 42.14 and 42.54

Jul 13, 2022PAPERBOARD

Patent Owner's Second Updated Mandatory Notices

Jul 13, 2022PAPERPATENT OWNER

Patent Owner's Updated Power of Attorney (Novartis Pharma AG)

Jul 13, 2022PAPERPATENT OWNER

Patent Owner's Updated Power of Attorney (Novartis Pharmaceuticals Corporation)

Jul 13, 2022PAPERPATENT OWNER

Patent Owner's Updated Power of Attorney (Novartis Technology Corporation)

Jul 13, 2022PAPERPATENT OWNER

Petitioner's Opposition to Patent Owner's Motion to Exclude

Jul 12, 2022PAPERPETITIONER

Order: Granting Patent Owner's Third, Fourth, and Fifth Motions to Seal - Granting Patent Owner's Motion for Entry of Second Modified Default Protective Order - 37 CFR 42.14 and 42.54

Jul 8, 2022PAPERBOARD

Joint Notice to Modify Date to Serve Demonstratives on Opposing Counsel

Jul 6, 2022PAPERPATENT OWNER

Patent Owner's Motion to Exclude Evidence

Jul 5, 2022PAPERPATENT OWNER

Preliminary Guidance Patent Owner's Motion to Amend (PUBLIC VERSION)

Jun 30, 2022PAPERBOARD

Setting Oral Argument 37 C.F.R. § 42.70

Jun 27, 2022PAPERBOARD

Petitioners Request For Oral Argument

Jun 14, 2022PAPERPETITIONER

Patent Owner's Request for Oral Argument

Jun 14, 2022PAPERPATENT OWNER

Petitioner���s Updated Mandatory Notices Pursuant to 37 C.F.R �� 42.8

Jun 6, 2022PAPERPETITIONER

PETITIONER'S THIRD OBJECTIONS TO ADMISSIBILITY OF EVIDENCE SUBMITTED BY PATENT OWNER

Jun 3, 2022PAPERPETITIONER

Notice of Certification of Word Count for Patent Owners' Surreply to Petitioner's Reply

May 27, 2022PAPERPATENT OWNER

Patent Owner's Notice of Withdrawal of Its Contingent Motion to Amend

May 26, 2022PAPERPATENT OWNER

Patent Owner's Fifth Motion to Seal

May 26, 2022PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

May 26, 2022PAPERPATENT OWNER

Deposition Transcript of James Agalloco (May 4, 2022) [Redacted Version]

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of Joel M. Cohen (May 19, 2022)

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of Szilard Kiss, M.D., Vol. 2 (May 13, 2022) [Redacted Version]

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of Horst Koller, Vol. 2 (May 16, 2022) [Redacted Version]

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of James Agalloco (May 4, 2022) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of Kenneth S. Graham (May 20, 2022) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

February 17, 2011 Email (Graham Ex. 1; REGITC00073676) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

August 4, 2011 Report (Graham Ex. 2; REGITC00092067) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

August 2, 2017 Email (Graham Ex. 7; REG_SDNY_01751250) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of Szilard Kiss, M.D., Vol. 2 (May 13, 2022) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of Gerrit Moyer (April 20, 2022), Case No. 1:20-cv-00690 (N.D. NY) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of Horst Koller, Vol. 2 (May 16, 2022) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

Deposition Transcript of Lisa J. Cameron, Ph.D. (May 17, 2022)[Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

May 31, 2010 Email (Graham Ex. 3; REGITC00077226) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

May 16, 2011 Email (Graham Ex. 4; REGITC00088003) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

March 20, 2012 Email (Graham Ex. 5; REGITC00054921) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

March 13, 2012 Email (Graham Ex. 6; REGITC00260796) [Filed Under Seal]

May 26, 2022EXHIBITPATENT OWNER

Patent Owner's Surreply to Petitioner's Reply - CONFIDENTIAL

May 26, 2022PAPERPATENT OWNER

Patent Owner's Surreply to Petitioner's Reply - REDACTED

May 26, 2022PAPERPATENT OWNER

Order: Other

May 25, 2022PAPERBOARD

Exhibit 3002

May 25, 2022EXHIBITBOARD

Preliminary Guidance Patent Owner's Motion to Amend

May 12, 2022PAPERBOARD

Patent Owners' Fourth Motion to Seal

May 11, 2022PAPERPATENT OWNER

Akers and Agalloco 2013, Overcoming Limitations of Vaporized Hydrogen Peroxide

May 11, 2022EXHIBITPATENT OWNER

Agalloco 2008, Chapter in Pharmaceutical Manufacturing Handbook

May 11, 2022EXHIBITPATENT OWNER

Deposition Transcript of James Agalloco (Feb. 16, 2021) [Filed Under Seal]

May 11, 2022EXHIBITPATENT OWNER

EXPUNGED

May 11, 2022EXHIBITPATENT OWNER

Patent Owners' Updated Exhibit List

May 11, 2022PAPERPATENT OWNER

Petitioner's Updated Exhibit List

May 6, 2022PAPERPETITIONER

Patent Owners' Notice of Deposition of Horst Koller Under 37 C.F.R. Section 42.53

May 4, 2022PAPERPATENT OWNER

Patent Owners' Notice of Deposition of Joel M. Cohen Under 37 C.F.R. Section 42.53

May 4, 2022PAPERPATENT OWNER

Patent Owners' Notice of Deposition of Kenneth S. Graham Under 37 C.F.R. Section 42.53

May 4, 2022PAPERPATENT OWNER

Patent Owners' Notice of Deposition of Lisa Cameron Under 37 C.F.R. Section 42.53

May 4, 2022PAPERPATENT OWNER

Patent Owners' Notice of Deposition of W. Gregory Sawyer Under 37 C.F.R. Section 42.53

May 4, 2022PAPERPATENT OWNER

Patent Owners' Notice of Deposition of James Agalloco Under 37 C.F.R. Section 42.53

May 3, 2022PAPERPATENT OWNER

Patent Owners' Notice of Deposition of Szilard Kiss Under 37 C.F.R. Section 42.53

May 3, 2022PAPERPATENT OWNER

Patent Owners' Objections To Admissibility of Evidence Submitted by Petitioner

Apr 22, 2022PAPERPATENT OWNER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00114439 - Regeneron Confidential Report

Apr 15, 2022EXHIBITPETITIONER

REGITC00042686 - Vetter Confidential Report

Apr 15, 2022EXHIBITPETITIONER

REGITC00264748 - Regeneron Confidential Report

Apr 15, 2022EXHIBITPETITIONER

Declaration of James Agalloco

Apr 15, 2022EXHIBITPETITIONER

Declaration of James Agalloco

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Declaration of Dr. Kenneth Graham

Apr 15, 2022EXHIBITPETITIONER

Declaration of Dr. Kenneth Graham

Apr 15, 2022EXHIBITPETITIONER

REGITC00149282 ��� Regeneron Confidential Report

Apr 15, 2022EXHIBITPETITIONER

Second Declaration of James L. Mullins, Ph.D.

Apr 15, 2022EXHIBITPETITIONER

BD-ITC-000010 ��� Becton Dickinson Confidential Report

Apr 15, 2022EXHIBITPETITIONER

Reply Declaration of Horst Koller

Apr 15, 2022EXHIBITPETITIONER

STERIS_00000489 - Steris Report

Apr 15, 2022EXHIBITPETITIONER

Reply Declaration of Horst Koller

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 - Regeneron Confidential Report (1/9)

Apr 15, 2022EXHIBITPETITIONER

Reply Declaration of Dr. Szilard Kiss

Apr 15, 2022EXHIBITPETITIONER

Reply Declaration of Dr. Szilard Kiss

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 ��� Regeneron Confidential Report (2/9)

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 ��� Regeneron Confidential Report (3/9)

Apr 15, 2022EXHIBITPETITIONER

Declaration of Lisa Cameron

Apr 15, 2022EXHIBITPETITIONER

Declaration of Lisa Cameron

Apr 15, 2022EXHIBITPETITIONER

Declaration of Joel M. Cohen

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 - Regeneron Confidential Report (4/9)

Apr 15, 2022EXHIBITPETITIONER

NOVITC(CH)02909828 - Novartis Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

Deposition of Kim Cameron, Ph.D., (3/17/2022)

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 - Regeneron Confidential Report (5/9)

Apr 15, 2022EXHIBITPETITIONER

Deposition of Kim Cameron, Ph.D., (3/17/2022)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 - Regeneron Confidential Report (6/9)

Apr 15, 2022EXHIBITPETITIONER

Nishimoto, et al., Determination of Conditions for the Production Scale Sterilization of Prefilled Syringes, 57 PDA J Pharm Sci. & Tech, 378-386 (2003)

Apr 15, 2022EXHIBITPETITIONER

Declaration of Gerrit Moyer

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 - Regeneron Confidential Report (7/9)

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 - Regeneron Confidential Report (8/9)

Apr 15, 2022EXHIBITPETITIONER

BD-ITC-000101 - Becton Dickinson Confidential Sales Information

Apr 15, 2022EXHIBITPETITIONER

REGITC00122265 - Regeneron Confidential Report (9/9)

Apr 15, 2022EXHIBITPETITIONER

NOVITC(CH)00137958 ��� Novartis Confidential Internal Memorandum

Apr 15, 2022EXHIBITPETITIONER

BAUSCH00014 - Bausch Confidential FDA Correspondence

Apr 15, 2022EXHIBITPETITIONER

REGITC00116953 - Vetter Confidential Report

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC01008782 - Vetter Confidential Report

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information,��� Lucentis, FDA, June 2006

Apr 15, 2022EXHIBITPETITIONER

Declaration of Lisa Cameron ��� List of Materials Considered

Apr 15, 2022EXHIBITPETITIONER

REGITC00381349 - Regeneron Confidential Report (1/5)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00381349 - Regeneron Confidential Report (2/5)

Apr 15, 2022EXHIBITPETITIONER

BAUSCH00035 - Bausch Confidential FDA Application (1/4)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00381349 - Regeneron Confidential Report (3/5)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00381349 - Regeneron Confidential Report (4/5)

Apr 15, 2022EXHIBITPETITIONER

Deposition of James E. Malackowski, IPR2021-00816 (3/29/2022)

Apr 15, 2022EXHIBITPETITIONER

REGITC00381349 - Regeneron Confidential Report (5/5)

Apr 15, 2022EXHIBITPETITIONER

BAUSCH00035 - Bausch Confidential FDA Application (2/4)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Deposition of James E. Malackowski, IPR2021-00816 (3/29/2022)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Jesse David and Marion Stewart, Commercial Success: Economic Principles Applied to Patent Litigation

Apr 15, 2022EXHIBITPETITIONER

BAUSCH00035 - Bausch Confidential FDA Application (3/4)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00255816 - Bayer Correspondence with EMEA

Apr 15, 2022EXHIBITPETITIONER

REGITC00883958 - Regeneron Confidential Memorandum

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

BAUSCH00035 - Bausch Confidential FDA Application (4/4)

Apr 15, 2022EXHIBITPETITIONER

REGITC00264472 - Regeneron Confidential Memorandum

Apr 15, 2022EXHIBITPETITIONER

T. McNelis, ���New Designs: Licenses May Be Evidence of the Nonobviousness of an Invention,��� Fenwick & West LLP, 1998

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC01066319 - Regeneron Confidential Memorandum

Apr 15, 2022EXHIBITPETITIONER

Turbert, ���Anti-VEGF Treatments,��� American Academy of Ophthalmology, March 2, 2019

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00149657 - EMA Assessment Report

Apr 15, 2022EXHIBITPETITIONER

REGITC00381924 - Regeneron Confidential Memorandum

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

BAUSCH00473 - Bausch FDA Correspondence

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00041726 - Regeneron Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

NOVITC(CH)00056469 - Novartis Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Lucentis, FDA, revised March 2018

Apr 15, 2022EXHIBITPETITIONER

REG_SDNY_02214433 - EMA Correspondence

Apr 15, 2022EXHIBITPETITIONER

REGITC00160863 - Regeneron Confidential Memorandum

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REGITC00110725 - Regeneron Confidential Emails

Apr 15, 2022EXHIBITPETITIONER

REGITC00117031 - Regeneron Confidential FDA Correspondence

Apr 15, 2022EXHIBITPETITIONER

NOVITC(CH)00217792 - Novartis Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

REGITC01116755 - Confidential Sales Data

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

NOVITC(CH)00337297 - Novartis Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Eylea, FDA, revised March 2021

Apr 15, 2022EXHIBITPETITIONER

Sigg ITC Deposition Transcript (12/17/2020)

Apr 15, 2022EXHIBITPETITIONER

Roettelle ITC Deposition Transcript (12/14/2020)

Apr 15, 2022EXHIBITPETITIONER

NOVITC(CH)00217100 - Novartis Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Petitioner's Motion to Seal

Apr 15, 2022PAPERPETITIONER

Sauer ITC Deposition Transcript (12/18/2020)

Apr 15, 2022EXHIBITPETITIONER

BD-ITC-000069 - Becton Dickinson Presentation

Apr 15, 2022EXHIBITPETITIONER

NOVITC(US)00016448 - Novartis Confidential Memorandum

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Petitioner's Reply to Patent Owner's Response

Apr 15, 2022PAPERPETITIONER

Petitioner's Reply to Patent Owner's Response

Apr 15, 2022PAPERPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Novartis Ophthalmics and Genentech announce development and commercialization agreement for age-related macular degeneration treatment, Lucentis(TM), Novartis Pharma AG press release, June 25, 2003

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

VETTER_10001435_EN (Certified Translation)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Curriculum Vitae of Lisa Cameron

Apr 15, 2022EXHIBITPETITIONER

Petitioner's Opposition to Patent Owner's Contingent Motion to Amend

Apr 15, 2022PAPERPETITIONER

Petitioner's Opposition to Patent Owner's Contingent Motion to Amend

Apr 15, 2022PAPERPETITIONER

Bayer HealthCare AG And Regeneron Pharmaceuticals, Inc. To Collaborate On VEGF Trap For The Treatment Of Eye Diseases Regeneron Retains U.S. Commercialization Rights, Receives $75 Million Upfront, October 19, 2006

Apr 15, 2022EXHIBITPETITIONER

Eylea Prefilled Syringe Now Available,��� Healio, December 12, 2019

Apr 15, 2022EXHIBITPETITIONER

REG_NDNY_00000004 - Gilead Sciences Inc. Form 10-K (1/6)

Apr 15, 2022EXHIBITPETITIONER

REG_NDNY_00000004 - Gilead Sciences Inc. Form 10-K (2/6)

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

REG_NDNY_00000004 - Gilead Sciences Inc. Form 10-K (3/6)

Apr 15, 2022EXHIBITPETITIONER

Mali Okada et al., Nonadherence or Nonpersistence to Intravitreal Injection Therapy for Neovascular Age-Related Macular Degeneration: A Mixed Methods Systematic Review, Ophthalmology 128(2):234-247, August 5, 2020

Apr 15, 2022EXHIBITPETITIONER

REG_NDNY_00000004 - Gilead Sciences Inc. Form 10-K (4/6)

Apr 15, 2022EXHIBITPETITIONER

Mali Okada, Tien Yin Wong, Paul Mitchell, et al., Defining Nonadherence and Nonpersistence to Anti���Vascular Endothelial Growth Factor Therapies in Neovascular Age-Related Macular Degeneration, JAMA Ophthalmology 139(7): 769-776, June 3, 2021

Apr 15, 2022EXHIBITPETITIONER

Turbert, What is Avastin?, American Academy of Ophthalmology, April 23, 2021

Apr 15, 2022EXHIBITPETITIONER

REGITC01117015 ��� Regeneron Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

REG_NDNY_00000004 - Gilead Sciences Inc. Form 10-K (5/6)

Apr 15, 2022EXHIBITPETITIONER

REG_NDNY_00000004 - Gilead Sciences Inc. Form 10-K (6/6)

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information, Avastin, FDA, revised December 2020

Apr 15, 2022EXHIBITPETITIONER

Lambert, Rationale for practical medical device accelerated aging programs in AAMI TIR 17, Radiation Physics and Chemistry, 57 (2000) 349-353

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Callan Navitsky, The Regulation of Compounding Pharmacies, Retina Today, November/December 2012

Apr 15, 2022EXHIBITPETITIONER

Center for Drug Evaluation and Research, Application No. NDA 22-220, Trivaris

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information, Beovu, revised March, 2022

Apr 15, 2022EXHIBITPETITIONER

Internet Archive WayBack Machine, Eyetech, Inc.: Science, Vision, Hope

Apr 15, 2022EXHIBITPETITIONER

International Organization for Standardization, ISO 11040-5, Prefilled syringes - Part 5: Plunger stoppers for injectables (3d. ed. 2012) (���ISO 11040-5���)

Apr 15, 2022EXHIBITPETITIONER

US FDA approves updated Novartis Beovu�� label, to include additional safety information, Novartis press release, June 11, 2020

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Lucentis, FDA, revised February 2015

Apr 15, 2022EXHIBITPETITIONER

Angus Liu, Novartis calls off 3 Beovu trials testing more frequent dosing on concerns of vision-threatening side effect, FiercePharma, June 1, 2021

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Eylea, FDA, revised August 2019

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Eylea, FDA, revised September 2012

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information, Macugen, revised July 2011

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Eylea, FDA, revised October 2014

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information, Susvimo, revised October 2021,

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Eylea, FDA, revised March 2015

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Lucentis, FDA, revised February 2013

Apr 15, 2022EXHIBITPETITIONER

Susvimo 10 Mg/0.1Ml Implant Solution Macular Degeneration Treatment Agents-VEGF Antagonist Type- Uses, Side Effects, and More, WebMD

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Lucentis, FDA, revised April 2017

Apr 15, 2022EXHIBITPETITIONER

FDA Approves Genentech���s Susvimo, a First-of- Its-Kind Therapeutic Approach for Wet Age-Related Macular Degeneration (AMD), Genentech press release, October 22, 2021

Apr 15, 2022EXHIBITPETITIONER

���Highlights of Prescribing Information,��� Eylea, FDA, revised May 2019

Apr 15, 2022EXHIBITPETITIONER

Jonathan Gardner, Roche wins FDA approval for rival to Regeneron���s lucrative eye drug, BioPharma Dive, January 31, 2022

Apr 15, 2022EXHIBITPETITIONER

R. DeForest McDuff, Ryan C. Andrews, and Matt D. Brundage, Thinking Economically about Commercial Success, Landslide, 9(4): 1-5 (Mar./Apr. 2017)

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information, Vabysmo, revised January 2022,

Apr 15, 2022EXHIBITPETITIONER

Kevin L. Varghese, No Need to Neglect Nexus: Prosecution Lessons from FOX Factory v. SRAM, Intellectual Property & Tech. Law J., 32(6): 16 (June 2020)

Apr 15, 2022EXHIBITPETITIONER

Jarosz and Vigil International In-house Counsel Journal Summer 2015 Assessing Commercial Success at the U.S. Patent Trial and Appeal Board

Apr 15, 2022EXHIBITPETITIONER

Ernst R. Berndt et al., Information, Marketing, and Pricing in the U.S. Antiulcer Drug Market, The American Economic Review 85(2): 102-103 (1995)

Apr 15, 2022EXHIBITPETITIONER

Excerpt of Opening Report of Szilard Kiss, M.D., ITC Inv. No. 337-TA-1207 (Jan. 22, 2021)

Apr 15, 2022EXHIBITPETITIONER

Excerpt of Opening Report of Szilard Kiss, M.D., ITC Inv. No. 337-TA-1207 (Jan. 22, 2021)

Apr 15, 2022EXHIBITPETITIONER

Excerpt of "Research Design: Model Specification,��� Reference Manual on Scientific Evidence, 3rd edition, National Academics Press, 2011

Apr 15, 2022EXHIBITPETITIONER

Excerpt of Wooldridge, Jeffrey M., Econometric Analysis of Cross Section and Panel Data, MIT Press

Apr 15, 2022EXHIBITPETITIONER

GlobalData Healthcare, The dominance of Eylea is expected to persist in the foreseeable future, Pharma Tech., July 1, 2020 (updated Dec. 1, 2021)

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information, Lucentis, FDA, revised October 2016

Apr 15, 2022EXHIBITPETITIONER

Helen Marshall, Eylea (aflibercept), Medical News Today, February 16, 2020

Apr 15, 2022EXHIBITPETITIONER

REG_SDNY_03832114 - Confidential Sales Data

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information, Lucentis, FDA, revised January 2017

Apr 15, 2022EXHIBITPETITIONER

REGITC01116432 - Confidential Sales Data

Apr 15, 2022EXHIBITPETITIONER

Highlights of Prescribing Information, Lucentis, FDA, revised August 2012

Apr 15, 2022EXHIBITPETITIONER

REGITC00376214 - Novartis Completes Safety Review and Initiates Update to the Beovu Information Worldwide

Apr 15, 2022EXHIBITPETITIONER

NOVITCCH00190794 ��� Novartis Confidential Letter

Apr 15, 2022EXHIBITPETITIONER

Eric Sagonowsky, Novartis��� hot new eye drug Beovu tied to potential vision loss: experts (Feb. 24, 2020)

Apr 15, 2022EXHIBITPETITIONER

Application No. 13382380 File History Excerpts

Apr 15, 2022EXHIBITPETITIONER

Our Services, Vetter, accessed February 24, 2022

Apr 15, 2022EXHIBITPETITIONER

REGITC00375880 ��� Regeneron Confidential Agreement

Apr 15, 2022EXHIBITPETITIONER

Excerpt of ITC Inv. No. 337-TA-1207, Complainants��� Substitute Pre-Hearing Brief (Public Version), March 30, 2021

Apr 15, 2022EXHIBITPETITIONER

GENEITC_1207-0003331 ��� Genentech Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

Deposition of Karl R. Leinsing, IPR2021-00816 (3/24/2022)

Apr 15, 2022EXHIBITPETITIONER

Deposition of Andrew F. Calman, IPR2021-00816

Apr 15, 2022EXHIBITPETITIONER

NOVITCCH02018792 - Novartis Confidential Presentation

Apr 15, 2022EXHIBITPETITIONER

GILEAD00043 - Gilead Confidential Sales Information

Apr 15, 2022EXHIBITPETITIONER

GILEAD00044 ��� Gilead Confidential Sales Information

Apr 15, 2022EXHIBITPETITIONER

EXPUNGED

Apr 15, 2022EXHIBITPETITIONER

Deposition of John Dillberger, IPR2021-00816

Apr 15, 2022EXHIBITPETITIONER

Deposition of Michael J. Miller, IPR2021-00816

Apr 15, 2022EXHIBITPETITIONER

Deposition of Michael J. Miller, IPR2021-00816

Apr 15, 2022EXHIBITPETITIONER

Deposition of Marie Picci, IPR2021-00816 (3/31/2022)

Apr 15, 2022EXHIBITPETITIONER

Deposition of Jeremy Wolfe, IPR2021-00816 (3/19/2022)

Apr 15, 2022EXHIBITPETITIONER

Deposition of Juergen Sigg, IPR2021-00816 (4/12/2022)

Apr 15, 2022EXHIBITPETITIONER

Kinney, Delivering Therapeutic siRNA, Drug Delivery Technology, Vol. 9, No. 2 (Feb. 2009)

Apr 15, 2022EXHIBITPETITIONER

Joint Stipulation to Modify Due Dates 2 and 3

Apr 8, 2022PAPERPATENT OWNER

Granting Patent Owner Motion for Admission Pro Hac Vice of John T. Bennett and Daniel P. Margolis 37 C.F.R. § 42.10

Apr 5, 2022PAPERBOARD

Petitioner's Updated Mandatory Notices Pursuant to 37 C.F.R. 42.8

Mar 30, 2022PAPERPETITIONER

Patent Owners��� Motion for Pro Hac Vice Admission of John T. Bennett and Daniel P. Margolis 37 C.F.R. �� 42.10 (c)

Mar 24, 2022PAPERPATENT OWNER

Ex. 2333 - Declaration of John T. Bennett in Support of Patent Owners��� Motion for Pro Hac Vice Admission of John T. Bennett Under 37 C.F.R. 42.10 (c)

Mar 24, 2022EXHIBITPATENT OWNER

Ex. 2334 - Declaration of Daniel P. Margolis in Support of Patent Owners Motion for Pro Hac Vice Admission of Daniel P. Margolis Under 37 C.F.R. 42.10 (c)

Mar 24, 2022EXHIBITPATENT OWNER

Patent Owners Updated Exhibit List

Mar 24, 2022PAPERPATENT OWNER

Order: Appointing Commissioners and Direction of Submission

Mar 8, 2022PAPERBOARD

2022-03-07 - Petitioner's Updated Mandatory Notices

Mar 7, 2022PAPERPETITIONER

Panel Change Order

Mar 3, 2022PAPERBOARD

Patent Owner Novartis Pharma AG's Updated Power of Attorney

Mar 3, 2022PAPERPATENT OWNER

Patent Owner Novartis Pharmaceuticals Corporation's Updated Power of Attorney

Mar 3, 2022PAPERPATENT OWNER

Patent Owner Novartis Technology LLC's Updated Power of Attorney

Mar 3, 2022PAPERPATENT OWNER

Patent Owners' Updated Mandatory Notices

Mar 3, 2022PAPERPATENT OWNER

Joint Motion for the Appointment of Commissioners and Direction of Submission of Hague Convention Application

Mar 3, 2022PAPERPATENT OWNER

Ex. 2330 - Order appointing Swiss Commissioners, International Trade Commission Inv. No. 337-1207, Certain Pre-Filled Syringes for Intravitreal Injection and Components Thereof

Mar 3, 2022EXHIBITPATENT OWNER

Ex. 2331 - Order appointing Swiss Commissioners, Novartis Pharma AG et al v. Regeneron Pharmaceuticals, Inc., No. 1:20-cv00690-DH-CFH (NDNY)

Mar 3, 2022EXHIBITPATENT OWNER

Ex. 2332 - Proposed Order Appointing Commissioners

Mar 3, 2022EXHIBITPATENT OWNER

Patent Owners' Updated Exhibit List

Mar 3, 2022PAPERPATENT OWNER

IPR2021-00816 Deposition Notice of Kimberly Cameron

Mar 2, 2022PAPERPETITIONER

IPR2021-00816 Deposition Notice of Juergen Sigg

Mar 2, 2022PAPERPETITIONER

IPR2021-00816 Deposition Notice of Marie Picci

Mar 2, 2022PAPERPETITIONER

IPR2021-00816 Deposition Notice of Karl Leinsing

Mar 2, 2022PAPERPETITIONER

IPR2021-00816 Deposition Notice of Michael Miller

Mar 2, 2022PAPERPETITIONER

Deposition Notice of Andrew F. Calman

Mar 2, 2022PAPERPETITIONER

Deposition Notice of John Dillberger

Mar 2, 2022PAPERPETITIONER

Deposition Notice of James Malackowski

Mar 2, 2022PAPERPETITIONER

Deposition Notice of Jeremy Wolfe

Mar 2, 2022PAPERPETITIONER

Petitioner's Updated Power of Attorney

Feb 15, 2022PAPERPETITIONER

Petitioner's Updated Mandatory Notices

Feb 15, 2022PAPERPETITIONER

ORDER Granting Petitioners Motion for Pro Hac Vice Admission of Robert Vlasis 37 C.F.R. sec 42.10

Jan 27, 2022PAPERBOARD

IPR2021-00816, 2022-01-25, Motion for Pro Hac Vice - Robert Vlasis

Jan 26, 2022PAPERPETITIONER

PETITIONER���S SECOND OBJECTIONS TO ADMISSIBILITY OF EVIDENCE SUBMITTED BY PATENT OWNER

Jan 26, 2022PAPERPETITIONER

IPR2021-00816, 2022-01-25, Updated Exhibit List

Jan 25, 2022PAPERPETITIONER

Ex. 1098, Declaration of Robert T. Vlasis ISO Motion for Pro Hac Vice

Jan 25, 2022EXHIBITPETITIONER

Ex. 1099, Bio for Robert T. Vlasis - Weil Gotshal Manges

Jan 25, 2022EXHIBITPETITIONER

Ex. 2208 ��� Cameron Declaration [PUBLIC REDACTED VERSION]

Jan 20, 2022EXHIBITPATENT OWNER

Ex. 2257 - Kiss Depo Tr.

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2194 - Overcashier Dep. Tr. Part 1 of 2 [FILED UNDER SEAL]

Jan 19, 2022EXHIBITPATENT OWNER

Exhibit 2194- Overcashier Dep. Tr. Part 2 of 2 [FILED UNDER SEAL]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2161 - Roche Finance Report for 2016

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2163 - Roche Finance Report for 2019

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2258 - Macular Degeneration Treatments

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2259 - Avastin Prescribing Information Part 1 of 4

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2259 - Avastin Prescribing Information Part 2 of 4

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2259 - Avastin Prescribing Information Part 3 of 4

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2125 - Lucentis Prescribing Information, revised March 2018

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2162 - Roche Finance Report for 2014

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2259 - Avastin Prescribing Information Part 4 of 4

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2260 - Comparison of Anti VEGF Treatments

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2261 - Age-Related Macular Degeneration Facts & Figures

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2262 - FDA Approves Avastin Article

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2264 - Roche March 22, 2018 Investor Update

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2265 - Genentech, Inc. Form 10K for the period ending 12312003

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2266 - FDA Approves Lucentis Article

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2269 - FDA Approves Eylea Article

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2270 - FDA Approves Eylea PFS Article

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2271 - Prefilled Syringe Delivery of Intravitreal Anti-VEGF Medications

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2272 - Excerpted Chris Simms Transcript

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2273 - Roche Finance Report for 2011

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2274 - Roche Finance Report for 2012 Part 1 of 2

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2274 - Roche Finance Report for 2012 Part 2 of 2

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2275 - Roche Finance Report for 2015 Part 1 of 2

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2275 - Roche Finance Report for 2015 Part 2 of 2

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2276 - Roche Finance Report for 2017 Part 1 of 3

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2276 - Roche Finance Report for 2017 Part 2 of 3

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2276 - Roche Finance Report for 2017 Part 3 of 3

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2277 - Treatments for Wet AMD

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2142 - NOVITC(CH)01494800 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2119 - NOVITC(CH)00003455 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2128 - NOVITC(CH)00167663 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2130 - NOVITC(CH)00169036 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2138 - NOVITC(CH)00217650 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2139 - NOVITC(CH)00810847 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2141 - NOVITC(CH)00880433 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2144 - NOVITC(CH)01498292 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2146 - NOVITC(CH)01863785 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2147 - NOVITC(CH)01906307 [PUBLIC REDACTED VERSION]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2118 - NOVITC(CH)00002720 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2152 - NOVITC(US)00000788 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2153 - NOVITC(US)00000792 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2154 - NOVITC(US)00000795 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2155 - NOVITC(US)00006151 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2156 - NOVITC(US)00006173 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2157 - NOVITC(US)00006182 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2158 - NOVITC(US)00006196 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2159 - NOVITC(US)00006213 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2164 - Roche Finance Report 2013 Part 1 of 2

Jan 19, 2022EXHIBITPATENT OWNER

Exhibit 2164 - Roche Finance Report 2013 Part 2 of 2

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2166 - NOVITC(US)00389194 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex.. 2167 - NOVITC(US)00394737 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2168 - NOVITC(US)00395564 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2169 - NOVITC(US)00395565 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2170 - NOVITC(US)00507243 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2171 - NOVITC(US)00697489 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2172 - NOVITC(US)00718202 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2185 - Ansel 1995

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2186 - Lachman 1986

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Ex. 2187 - ANSIAAMI ST67-2011

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Ex. 2188 - ISO 14161

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Ex. 2190 - Bash and Gould 1984

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Ex. 2191 - CFR 2004

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Ex. 2192 - CFR 2008

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Ex. 2193 - CFR 2021

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Ex. 2195 - Poche 2019

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2196 - ISO 10993-7-2008

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2197 - Eylea PFS Label Aug 2019

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2203 - Declaration of Michael J Miller [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2204 - Calman Declaration [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2206 - Declaration of Juergen Sigg [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2300 - Yoon 2009

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2121 - NOVITC(CH)00005765 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Patent Owner's Updated Exhibit List

Jan 19, 2022PAPERPATENT OWNER

Ex. 2120 - NOVITC(CH)00004818 [Public Redacted Version - Replacement]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2123 - NOVITC(CH)00007283 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2124 - NOVITC(CH)00008409 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2126 - NOVITC(CH)00054063 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2129 - NOVITC(CH)00168961 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2131 - NOVITC(CH)00170304 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2205 - Malackowski Declaration [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2133 - NOVITC(CH)00170896 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2134 - NOVITC(CH)00170915 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2136 - NOVITC(CH)00217349 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2137 - NOVITC(CH)00217646 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2140 - NOVITC(CH)00874056 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2143 - NOVITC(CH)01495912 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2145 - NOVITC(CH)01863737 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2148 - NOVITC(CH)02022271 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2150 - NOVITC(CH)02929814 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2201 - Supplemental Leinsing [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Ex. 2254 - NOVITC(CH)00885630 [Public Redacted Version]

Jan 19, 2022EXHIBITPATENT OWNER

Novartis Pharma AG, Novartis Technology LLC, and Novartis Pharmaceuticals Corporation's Patent Owner Response [PUBLIC REDACTED VERSION]

Jan 19, 2022PAPERPATENT OWNER

Joint Stipulation to Modify Due Dates 1 and 2

Jan 19, 2022PAPERPATENT OWNER

IPR2021-00816, Petitioner's Updated Power of Attorney

Jan 18, 2022PAPERPETITIONER

2022-01-18, Petitioner's Updated Exhibit List

Jan 18, 2022PAPERPETITIONER

Ex. 1097, 2022-01-06 Telephonic Conference

Jan 18, 2022EXHIBITPETITIONER

Ex. 2116 - Genentech Press Release

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2117 - Genentech Press Release

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2125 - Lucentis Prescribing Information

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2160 - Lucentis PFS Letter and Label

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2161 - Roche Finance Report for 2016

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2162 - Roche Finance Report for 2014

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2163 - Roche Finance Report for 2019

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2174 - WHO Guidelines on Packaging for Pharmaceutical Products

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2176 - Boven 2005

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2177 - Tzannis 1996

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2178 - Markovic 2009

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2179 - Markovic 2011

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2180 - Silver 2008

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2175 - Akers 2010

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2181 - ISO-10993-1-2009

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2182 - Helmus 2008

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2183 - FDA Use of ISO-10993

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2184 - Rathore 2008

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2198 - Venook Declaration

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2199 - ISO 11137

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2200 - Von Woedtke and Kramer

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2253 - Jones 2005

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2255 - Teng 2012

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2278 - Eylea PFS PBS Listed, Indications Expanded ��� minivision

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2279 - Macugen European Medicines Agency - EPAR website

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2215 - Storey et al. 2019

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2227 - Application No. 13/750,352

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2228 - FDA Guidance for Industry ��� Q1A (R2) Stability Testing of New Drug Substances and Products (2003)

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2231 - EYLEA Approval Letter

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2232 - Freund 2006

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2224 - DSR5092D [PUBLIC REDACTED VERSION]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2099 - GENEITC_1207-0000030 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2100 - GENEITC_1207-0001660 Part 1 of 3 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2100 - GENEITC_1207-0001660 Part 2 of 3 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2100 - GENEITC_1207-0001660 Part 3 of 3 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2101 - GENEITC_1207-0001864 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2102 - GENEITC_1207-0002423 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2103 - GENEITC_1207-0002825 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2104 - GENEITC_1207-0003003 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2105 - GENEITC_1207-0003160 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2106 - GENEITC_1207-0003163 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2107 - GENEITC_1207-0003412 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2108 - GENEITC_1207-0003418 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2109 - GENEITC_1207-0003503 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2110 - GENEITC_1207-0003545 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2111 - GENEITC_1207-0003551 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2112 - GENEITC_1207-0003675 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2113 - GENEITC_1207-0003683 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2114 - GENEITC_1207-0003704 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Exhibit 2115 - GENEITC_1207-0002409 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2125 - Lucentis Prescribing Information, revised March 2018

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2256 - Calman CV

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2280 - Michaud 2014

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2281 - Krzystolik 2002

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2282 - FDA Approval for Macugen

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2283 - FDA Approved Drugs Page for Macugen

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2284 - Rich 2006

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2285 - Avastin FDA Label

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2286 - Eylea FDA approval letter

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2287 - Federman 1998

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2288 - Nguyen 1992

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2289 - Scott 2003

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Ex. 2291 - Rosenberg 2006

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Ex. 2292 - Charles 2009

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Ex. 2293 - Stepien 2009

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Ex. 2294 - Beovu approval letter

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Ex. 2295 - Mittra 2006

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Ex. 2296 - Santaella 2007

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Ex. 2297 - Abbasi 2009

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Ex. 2298 - Schatz 1986

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2299 - Peck 2010

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Ex. 2301 - Lang 2007

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Ex. 2302 - Chen 2013

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Ex. 2303 - Sarao 2014

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Ex. 2304 - Baudin 2018

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Ex. 2305 - Wilson 2013

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Ex. 2306 - Kamjoo 2021

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Ex. 2307 - Jonas 2003

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Ex. 2308 - Ramulu 2010

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Ex. 2309 - Asbell 2016

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Ex. 2310 - EVS Study Group 1995

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2311 - Dossarps 2015

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Ex. 2312 - Klein 2009

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Ex. 2313 - Green Simms 2011

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Ex. 2314 - McCannell 2011

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Ex. 2315 - Shimada 2013

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Ex. 2316 - Levinson 2018

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Ex. 2317 - Gallemore 2006

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Ex. 2318 - Ip 2004

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Ex. 2319 - Gedde 2006

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Ex. 2320 - Riedel 1990

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Ex. 2321 - Thompson 2021

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2322 - Kahook 2010

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2326 - FDA Eylea PFS Approval Letter

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2209 - Wolfe Declaration

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2202 - Declaration of John E. Dillberger

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2203 - Declaration of Michael J Miller [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2206 - Declaration of Juergen Sigg [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2323 - Second Modified Protective Order

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2324 - Redline of Second Modified Protective Order

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2325 - Declaration of Martina Athanas

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2224 - DSR5092D [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2119 - NOVITC(CH)00003455 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2121 - NOVITC(CH)00005765 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2124 - NOVITC(CH)00008409 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2126 - NOVITC(CH)00054063 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2128 - NOVITC(CH)00167663 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2129 - NOVITC(CH)00168961 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2130 - NOVITC(CH)00169036 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2131 - NOVITC(CH)00170304 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2132 - NOVITC(CH)00170859 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2133 - NOVITC(CH)00170896 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2134 - NOVITC(CH)00170915 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2136 - NOVITC(CH)00217349 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2137 - NOVITC(CH)00217646 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2138 - NOVITC(CH)00217650 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2139 - NOVITC(CH)00810847 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2140 - NOVITC(CH)00874056 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2141 - NOVITC(CH)00880433 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2142 - NOVITC(CH)01494800 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2143 - NOVITC(CH)01495912 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2144 - NOVITC(CH)01498292 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2145 - NOVITC(CH)01863737 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2146 - NOVITC(CH)01863785 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2147 - NOVITC(CH)01906307 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2148 - NOVITC(CH)02022271 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2150 - NOVITC(CH)02929814 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2155 - NOVITC(US)00006151 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2156 - NOVITC(US)00006173 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2157 - NOVITC(US)00006182 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2158 - NOVITC(US)00006196 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2159 - NOVITC(US)00006213 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2166 - NOVITC(US)00389194 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2167 - NOVITC(US)00394737 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2170 - NOVITC(US)00507243 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2171 - NOVITC(US)00697489 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2172 - NOVITC(US)00718202 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2254 - NOVITC(CH)00885630 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Novartis Pharma AG, Novartis Technology LLC, and Novartis Pharmaceuticals Corporation's Patent Owner Response

Jan 18, 2022PAPERPATENT OWNER

Ex. 2062 - Jeffrey Salling Declaration

Jan 18, 2022EXHIBITPATENT OWNER

NOVITC(CH)00004818 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2122 - NOVITC(CH)00006074 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2123 - NOVITC(CH)00007283 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2168 - NOVITC(US)00395564 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2169 - NOVITC(US)00395565 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2189 - Koller IPR Dep. Tr. Part 1 of 2

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2189 - Koller IPR Dep. Tr. Part 2 of 2

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2201 - Leinsing Supplemental Declaration [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2204 - Calman Declaration [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Patent Owner's Contingent Motion to Amend Under 37 C.F.R. Section 42.121 [PUBLIC REDACTED VERSION]

Jan 18, 2022PAPERPATENT OWNER

Patent Owner's Contingent Motion to Amend Under 37 C.F.R. Section 42.121 [FILED UNDER SEAL]

Jan 18, 2022PAPERPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

EXPUNGED

Jan 18, 2022EXHIBITPATENT OWNER

Patent Owners' Third Motion to Seal and Motion for a Modified Default Protective Order

Jan 18, 2022PAPERPATENT OWNER

Ex. 2168 - NOVITC(US)00395564 [FILED UNDER SEAL]

Jan 18, 2022EXHIBITPATENT OWNER

Ex. 2205 - Malackowski Declaration [FILED UNDER SEAL]_

Jan 18, 2022EXHIBITPATENT OWNER

IPR2021-00816, Petitioner's Updated Mandatory Notices

Jan 7, 2022PAPERPETITIONER

Order: Granting Patent Owner's Motion for Admission Pro Hac Vice of Nicholas K. Mitrokostas

Jan 5, 2022PAPERBOARD

Order: Granting Petitioner's Motion for Admission Pro Hac Vice of Petra Scamborova

Jan 5, 2022PAPERBOARD

Patent Owners Notice of Deposition of Szilard Kiss Under C.F.R. Section 42.53

Dec 23, 2021PAPERPATENT OWNER

Patent Owners Motion for Pro Hac Vice Admission of Nicholas K. Mitrokostas Under 37 C.F.R. Section 42.10(c)

Dec 22, 2021PAPERPATENT OWNER

Exhibit 2098 - Declaration of Nicholas K. Mitrokostas in Support of Patent Owners Motion for Pro Hac Vice Admission of Nicholas K. Mitrokostas Under 37 C.F.R. Section 42.10(c)

Dec 22, 2021EXHIBITPATENT OWNER

Patent Owners Updated Exhibit List

Dec 22, 2021PAPERPATENT OWNER

Motion: PHV

Dec 22, 2021PAPERPETITIONER

Notice: exhibit list

Dec 22, 2021PAPERPETITIONER

Declaration of Petra Scamborova

Dec 22, 2021EXHIBITPETITIONER

P. Scamborova LinkedIn Profile

Dec 22, 2021EXHIBITPETITIONER

Petitioner's Corrected First Supplemental Exhibit List

Dec 3, 2021PAPERPETITIONER

Patent Owners' Notice of Deposition of Horst Koller Under C.F.R. Section 42.53

Dec 2, 2021PAPERPATENT OWNER

Order: Granting Patent Owner's Second Motion to Seal - 37 CFR 42.14 and 42.54

Nov 30, 2021PAPERBOARD

EXPUNGED

Nov 23, 2021PAPERPETITIONER

EXPUNGED

Nov 23, 2021PAPERPETITIONER

EXPUNGED

Nov 23, 2021EXHIBITPETITIONER

EXPUNGED

Nov 23, 2021EXHIBITPETITIONER

EXPUNGED

Nov 23, 2021EXHIBITPETITIONER

EXPUNGED

Nov 23, 2021EXHIBITPETITIONER

Patent Owners Second Motion to Seal

Nov 19, 2021PAPERPATENT OWNER

Exhibit 2097 - Declaration of Martina Athanas In Support of Novartis���s Second Motion to Seal

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2063 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2064 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2066 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2067 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2068 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2069 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2070 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2071 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2072 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2073 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2074 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2075 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2076 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2077 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2078 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2079 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2080 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2081 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2082 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2083 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2084 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2085 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2086 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2087 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Exhibit 2088 [PUBLIC REDACTED VERSION]

Nov 19, 2021EXHIBITPATENT OWNER

Patent Owners Updated Exhibit List

Nov 19, 2021PAPERPATENT OWNER

Petitioner's Objections to Admissibility of Evidence Submitted by Patent Owner

Nov 9, 2021PAPERPETITIONER

Patent Owners Objections to Admissibility of Evidence Submitted by Petitioners

Nov 9, 2021PAPERPATENT OWNER

ORDER Denying Patent Owners Motion to Seal 37 C.F.R. sec s 42.14 and 42.54

Oct 28, 2021PAPERBOARD

Institution Decision: Grant

Oct 26, 2021PAPERBOARD

Order: Scheduling Order

Oct 26, 2021PAPERBOARD

Novartis Pharma AG, Novartis Technology LLC, and Novartis Pharmaceuticals Corporation���s Patent Owner Sur-Reply

Aug 27, 2021PAPERPATENT OWNER

Exhibit 2093

Aug 27, 2021EXHIBITPATENT OWNER

Exhibit 2094

Aug 27, 2021EXHIBITPATENT OWNER

Exhibit 2095

Aug 27, 2021EXHIBITPATENT OWNER

Exhibit 2096

Aug 27, 2021EXHIBITPATENT OWNER

E-Mail

Aug 27, 2021EXHIBITBOARD

Petitioner's Reply to Patent Owner's Preliminary Response

Aug 20, 2021PAPERPETITIONER

Text Minute Entry re Rule 16 Conference held on August 18, 2021, Novartis Pharma AG et al v. Regeneron Pharma., Inc., No. 1:20-cv-00690 (N.D.N.Y. Aug. 18, 2021)

Aug 20, 2021EXHIBITPETITIONER

Novartis Pharma AG, Novartis Technology LLC, and Novartis Pharmaceuticals Corporation���s Patent Owner Preliminary Response

Jul 28, 2021PAPERPATENT OWNER

Patent Owners��� Unopposed Motion for a Modified Default Protective Order

Jul 28, 2021PAPERPATENT OWNER

Patent Owners��� Motion to Seal

Jul 28, 2021PAPERPATENT OWNER

Declaration of Karl R. Leinsing, PE

Jul 28, 2021EXHIBITPATENT OWNER

Declaration of Marie Picci [Filed Under Seal]

Jul 28, 2021EXHIBITPATENT OWNER

Declaration of Marie Picci [Public Redacted Version]

Jul 28, 2021EXHIBITPATENT OWNER

2003

Jul 28, 2021EXHIBITPATENT OWNER

2004

Jul 28, 2021EXHIBITPATENT OWNER

2005

Jul 28, 2021EXHIBITPATENT OWNER

2006

Jul 28, 2021EXHIBITPATENT OWNER

2007

Jul 28, 2021EXHIBITPATENT OWNER

2008

Jul 28, 2021EXHIBITPATENT OWNER

2009

Jul 28, 2021EXHIBITPATENT OWNER

2010

Jul 28, 2021EXHIBITPATENT OWNER

2011

Jul 28, 2021EXHIBITPATENT OWNER

2012

Jul 28, 2021EXHIBITPATENT OWNER

2013

Jul 28, 2021EXHIBITPATENT OWNER

2014

Jul 28, 2021EXHIBITPATENT OWNER

2015

Jul 28, 2021EXHIBITPATENT OWNER

2016

Jul 28, 2021EXHIBITPATENT OWNER

2017

Jul 28, 2021EXHIBITPATENT OWNER

2018

Jul 28, 2021EXHIBITPATENT OWNER

2019

Jul 28, 2021EXHIBITPATENT OWNER

2020

Jul 28, 2021EXHIBITPATENT OWNER

2021

Jul 28, 2021EXHIBITPATENT OWNER

2022

Jul 28, 2021EXHIBITPATENT OWNER

2023

Jul 28, 2021EXHIBITPATENT OWNER

2024

Jul 28, 2021EXHIBITPATENT OWNER

2025

Jul 28, 2021EXHIBITPATENT OWNER

2026

Jul 28, 2021EXHIBITPATENT OWNER

2027

Jul 28, 2021EXHIBITPATENT OWNER

2028

Jul 28, 2021EXHIBITPATENT OWNER

2029

Jul 28, 2021EXHIBITPATENT OWNER

2030

Jul 28, 2021EXHIBITPATENT OWNER

2031

Jul 28, 2021EXHIBITPATENT OWNER

2032

Jul 28, 2021EXHIBITPATENT OWNER

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Jul 28, 2021EXHIBITPATENT OWNER

2034

Jul 28, 2021EXHIBITPATENT OWNER

2035

Jul 28, 2021EXHIBITPATENT OWNER

2036

Jul 28, 2021EXHIBITPATENT OWNER

2041

Jul 28, 2021EXHIBITPATENT OWNER

2042

Jul 28, 2021EXHIBITPATENT OWNER

2044

Jul 28, 2021EXHIBITPATENT OWNER

2045

Jul 28, 2021EXHIBITPATENT OWNER

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Jul 28, 2021EXHIBITPATENT OWNER

2047

Jul 28, 2021EXHIBITPATENT OWNER

2048

Jul 28, 2021EXHIBITPATENT OWNER

2049

Jul 28, 2021EXHIBITPATENT OWNER

2050

Jul 28, 2021EXHIBITPATENT OWNER

2051

Jul 28, 2021EXHIBITPATENT OWNER

2052

Jul 28, 2021EXHIBITPATENT OWNER

2053

Jul 28, 2021EXHIBITPATENT OWNER

2054

Jul 28, 2021EXHIBITPATENT OWNER

2055

Jul 28, 2021EXHIBITPATENT OWNER

2056

Jul 28, 2021EXHIBITPATENT OWNER

2057

Jul 28, 2021EXHIBITPATENT OWNER

2058

Jul 28, 2021EXHIBITPATENT OWNER

2059

Jul 28, 2021EXHIBITPATENT OWNER

2060

Jul 28, 2021EXHIBITPATENT OWNER

2061

Jul 28, 2021EXHIBITPATENT OWNER

Declaration of Jeffrey Salling

Jul 28, 2021EXHIBITPATENT OWNER

2063

Jul 28, 2021EXHIBITPATENT OWNER

2064

Jul 28, 2021EXHIBITPATENT OWNER

2065

Jul 28, 2021EXHIBITPATENT OWNER

2066

Jul 28, 2021EXHIBITPATENT OWNER

2067

Jul 28, 2021EXHIBITPATENT OWNER

2068

Jul 28, 2021EXHIBITPATENT OWNER

2069

Jul 28, 2021EXHIBITPATENT OWNER

2070

Jul 28, 2021EXHIBITPATENT OWNER

2071

Jul 28, 2021EXHIBITPATENT OWNER

2072

Jul 28, 2021EXHIBITPATENT OWNER

2073

Jul 28, 2021EXHIBITPATENT OWNER

2074

Jul 28, 2021EXHIBITPATENT OWNER

2075

Jul 28, 2021EXHIBITPATENT OWNER

2076

Jul 28, 2021EXHIBITPATENT OWNER

2077

Jul 28, 2021EXHIBITPATENT OWNER

2078

Jul 28, 2021EXHIBITPATENT OWNER

2079

Jul 28, 2021EXHIBITPATENT OWNER

2080

Jul 28, 2021EXHIBITPATENT OWNER

2081

Jul 28, 2021EXHIBITPATENT OWNER

2082

Jul 28, 2021EXHIBITPATENT OWNER

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Jul 28, 2021EXHIBITPATENT OWNER

2084

Jul 28, 2021EXHIBITPATENT OWNER

2085

Jul 28, 2021EXHIBITPATENT OWNER

2086

Jul 28, 2021EXHIBITPATENT OWNER

2087

Jul 28, 2021EXHIBITPATENT OWNER

2088

Jul 28, 2021EXHIBITPATENT OWNER

2089

Jul 28, 2021EXHIBITPATENT OWNER

2090

Jul 28, 2021EXHIBITPATENT OWNER

2091

Jul 28, 2021EXHIBITPATENT OWNER

2092

Jul 28, 2021EXHIBITPATENT OWNER

Patent Owner's Submission of Mandatory Notice Information Under 37 C.F.R. �� 42.8(a)(2)

May 7, 2021PAPERPATENT OWNER

Patent Owner Novartis Pharma AG's Power of Attorney

May 7, 2021PAPERPATENT OWNER

Patent Owner Novartis Pharmaceutical Corporation's Power of Attorney

May 7, 2021PAPERPATENT OWNER

Patent Owner Novartis Technology LLC's Power of Attorney

May 7, 2021PAPERPATENT OWNER

Notice of Accord Filing Date

Apr 28, 2021PAPERBOARD

PETITION FOR INTER PARTES REVIEW OF U.S. PATENT NO. 9,220,631

Apr 16, 2021PAPERPETITIONER

POWER OF ATTORNEY FOR PETITIONER REGENERON PHARMACEUTICALS, INC.

Apr 16, 2021PAPERPETITIONER

U.S. Patent No. 9,220,631 (���the ���631 Patent���)

Apr 16, 2021EXHIBITPETITIONER

Prosecution File History of U.S. Patent No. 9,220,631, part 1

Apr 16, 2021EXHIBITPETITIONER

Prosecution File History of U.S. Patent No. 9,220,631, part 2

Apr 16, 2021EXHIBITPETITIONER

Prosecution File History of U.S. Patent No. 9,220,631, part 3

Apr 16, 2021EXHIBITPETITIONER

Prosecution File History of U.S. Patent No. 9,220,631, part 4

Apr 16, 2021EXHIBITPETITIONER

Declaration of Horst Koller under 37 C.F.R. �� 1.68

Apr 16, 2021EXHIBITPETITIONER

Curriculum Vitae of Horst Koller

Apr 16, 2021EXHIBITPETITIONER

ITC Investigation No. 337-TA-1207, Staff���s Pre-Hearing Brief (public version)

Apr 16, 2021EXHIBITPETITIONER

ITC Investigation No. 337-TA-1207, Complainant���s Unopposed Motion to Terminate

Apr 16, 2021EXHIBITPETITIONER

PCT Patent Publication No. WO 2011/006877 to Sigg et al. (���Sigg���)

Apr 16, 2021EXHIBITPETITIONER

PCT Patent Publication No. WO 2009/030976 to Boulange et al. (���Boulange���)

Apr 16, 2021EXHIBITPETITIONER

Internet Archive WayBack Machine, March 7, 2011 Record of Drugs.com, Macugen Prescribing Information

Apr 16, 2021EXHIBITPETITIONER

ITC Investigation No. 337-TA-1207, Initial Determination Terminating the Investigation

Apr 16, 2021EXHIBITPETITIONER

Bhavnesh D. Shah & Bhupendra G. Prajapati, Pre-Filled Syringes: A New Concept, PHARMA BIO WORLD 51 (2009) (���Shah���)

Apr 16, 2021EXHIBITPETITIONER

Arno Fries, Drug Delivery of Sensitive Biopharmaceuticals With Prefilled Syringes, 9(5) DRUG DELIVERY TECH. 22 (2009) (���Fries���)

Apr 16, 2021EXHIBITPETITIONER

Thomas Schoenknecht, Prefilled Syringes: Why New Developments Are Important In Injectable Delivery Today, in PREFILLED SYRINGES INNOVATIONS THAT MEET THE GROWING DEMAND (OnDrugDelivery 2005) (���Schoenknecht���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Patent Publication No. 2012/0091026 to Chacornac et al. (���Chacornac���)

Apr 16, 2021EXHIBITPETITIONER

Sandeep Nema & John D. Ludwig, Pharmaceutical Dosage Forms: Parenteral Medications, Volume 1: Formulation and Packaging (3rd ed. 2010) (���Nema Vol. 1���), part 1

Apr 16, 2021EXHIBITPETITIONER

Sandeep Nema & John D. Ludwig, Pharmaceutical Dosage Forms: Parenteral Medications, Volume 1: Formulation and Packaging (3rd ed. 2010) (���Nema Vol. 1���), part 2

Apr 16, 2021EXHIBITPETITIONER

Sandeep Nema & John D. Ludwig, Pharmaceutical Dosage Forms: Parenteral Medications, Volume 1: Formulation and Packaging (3rd ed. 2010) (���Nema Vol. 1���), part 3

Apr 16, 2021EXHIBITPETITIONER

Sandeep Nema & John D. Ludwig, Pharmaceutical Dosage Forms: Parenteral Medications, Volume 1: Formulation and Packaging (3rd ed. 2010) (���Nema Vol. 1���), part 4

Apr 16, 2021EXHIBITPETITIONER

Sandeep Nema & John D. Ludwig, Pharmaceutical Dosage Forms: Parenteral Medications, Volume 2: Facility Design, Sterilization and Processing (3rd ed. 2010) (���Nema Vol. 2���), part 1

Apr 16, 2021EXHIBITPETITIONER

Sandeep Nema & John D. Ludwig, Pharmaceutical Dosage Forms: Parenteral Medications, Volume 2: Facility Design, Sterilization and Processing (3rd ed. 2010) (���Nema Vol. 2���), part 2

Apr 16, 2021EXHIBITPETITIONER

Sandeep Nema & John D. Ludwig, Pharmaceutical Dosage Forms: Parenteral Medications, Volume 2: Facility Design, Sterilization and Processing (3rd ed. 2010) (���Nema Vol. 2���), part 3

Apr 16, 2021EXHIBITPETITIONER

Sandeep Nema & John D. Ludwig, Pharmaceutical Dosage Forms: Parenteral Medications, Volume 2: Facility Design, Sterilization and Processing (3rd ed. 2010) (���Nema Vol. 2���), part 4

Apr 16, 2021EXHIBITPETITIONER

PCT Patent Publication No. WO 2007/035621 to Scypinski et al. (���Scypinski���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Patent Publication No. 2003/0003014 to Metzner et al. (���Metzner���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Pharmacopeia, USP 789, Particulate Matter in Ophthalmic Solutions, USP 34 NF 29 (2011)

Apr 16, 2021EXHIBITPETITIONER

U.S. Patent Publication No. 2011/276005 to Hioki et al. (���Hioki���)

Apr 16, 2021EXHIBITPETITIONER

PCT Patent Publication No. WO 2007/149334 to Furfine et al. (���Furfine���)

Apr 16, 2021EXHIBITPETITIONER

Michael W. Stewart et al., Fresh From the Pipeline Aflibercept, 11 NAT. REV. DRUG DISCOV. 269 (2012) (���Stewart���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Patent No. 7,060,269 to Baca et al. (���Baca���)

Apr 16, 2021EXHIBITPETITIONER

Gerald McDonnel and Denver Russell, Antiseptics and Disinfectants: Activities, Action, and Resistance, Clinical Microbiology Review, (Jan. 1999). (���McDonnel���)

Apr 16, 2021EXHIBITPETITIONER

Lu Liu et al., Silicone Oil Microdroplets and Protein Aggregates in Repackaged Bevacizumab and Ranibizumab: Effects of Long-term Storage and Product Mishandling, 52(2) INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 1023 (2011) (���Liu���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Patent No. 7,404,278 to Wittland et al. (���Wittland���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Food and Drug Administration, Lucentis�� Highlights of the Prescribing Information, (June 2010) (���Lucentis Label���)

Apr 16, 2021EXHIBITPETITIONER

International Organization for Standardization, ISO 11040-4 Prefilled Syringes ��� Part 4: Glass Barrels for Injectables (2nd ed. 2007) (���ISO 11040-4���)

Apr 16, 2021EXHIBITPETITIONER

PCT Patent Publication No. WO 2008/077155 to Lam et al. (���Lam���)

Apr 16, 2021EXHIBITPETITIONER

James A. Dixon, et al. "VEGF Trap-Eye for the treatment of neovascular age-related macular degeneration." Expert opinion on investigational drugs 18.10 (2009): 1573-1580. (���Dixon���)

Apr 16, 2021EXHIBITPETITIONER

Declaration of Dr. Szilard Kiss under 37 C.F.R. �� 1.68

Apr 16, 2021EXHIBITPETITIONER

Curriculum Vitae of Dr. Szilard Kiss

Apr 16, 2021EXHIBITPETITIONER

Declaration of James L. Mullins, Ph.D.

Apr 16, 2021EXHIBITPETITIONER

Dow Corning�� 365 35% Dimethicone NF Emulsion ��� Frequently Asked Questions (2002) (���DC365 FAQ���)

Apr 16, 2021EXHIBITPETITIONER

European Patent Application No. 12174860 to Novartis AG

Apr 16, 2021EXHIBITPETITIONER

EXPUNGED

Apr 16, 2021EXHIBITPETITIONER

Affidavit of Internet Archive Office Manager

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Internet Archive WayBack Machine, March 8, 2011 Record of Drugs.com, Welcome to Drugs.com

Apr 16, 2021EXHIBITPETITIONER

Internet Archive WayBack Machine, February 25, 2011 Record of Drugs.com, FDA Professional Drug Information

Apr 16, 2021EXHIBITPETITIONER

U.S. Food and Drug Administration, Eylea�� Highlights of the Prescribing Information, (November 2011) (���Eylea label���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Food and Drug Administration, Guidance for Industry: Container Closure Systems for Packaging Human and Biologics ��� Chemistry, Manufacturing, and Controls Documentation (May 1999)

Apr 16, 2021EXHIBITPETITIONER

International Standard ISO-7864, Sterile hypodermic needles for single use, ISO 7864:1993(E) (���ISO-7864���)

Apr 16, 2021EXHIBITPETITIONER

International Standard ISO-9626, Stainless steel needle tubing for the manufacture of medical devices ��� Amendment 1, ISO 9626:1991/Amd.1:2001(E) (���ISO-9626���)

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Advait Badkar, et al. Development of Biotechnology Products in Pre-filled Syringes: Technical Considerations and Approaches, American Association of Pharmaceutical Sciences, June 2011, 12(2): 564-572 (���Badkar���)

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William Leventon, ���Medical Device Sterilization: What Manufacturers Need to Know��� (MDDI online, Sept. 1, 2002)

Apr 16, 2021EXHIBITPETITIONER

Pamela Carter, et al. The lowdown on low temperature sterilization for packaged devices, Healthcare Purchasing News, July 2008, 42-45. (���Carter���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Patent Publication No. 2005/0182370 to Hato (���Hato���)

Apr 16, 2021EXHIBITPETITIONER

U.S. Department of Labor, Occupational Safety & Health Administration, Ethylene Oxide (EtO): Understanding OSHA���s Exposure monitoring Requirements, 2007 OSHA3325-01N (2007)

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Bryon Lambert, et al. Radiation and Ethylene Oxide Terminal Sterilization Experiences with Drug Eluting Stent Products, American Association of Pharmaceutical Sciences, December 2011, 12(4):1116-1126 (���Lambert���)

Apr 16, 2021EXHIBITPETITIONER

IPR2020-1317, Paper No. 10, Patent Owner���s Preliminary Response

Apr 16, 2021EXHIBITPETITIONER

IPR2020-1317, Paper No. 14, Patent Owner���s Sur-Reply

Apr 16, 2021EXHIBITPETITIONER

John R. Gillis & Gregg Mosley, Validation of Pharmaceutical Processes, Chapter 16 ��� Validation of Ethylene Oxide Sterilization Processes (2011), pp.241-262 (���Gillis���)

Apr 16, 2021EXHIBITPETITIONER

FDA Pesticide Analytical Manual Vol. 1, Chapter 6 - HPLC

Apr 16, 2021EXHIBITPETITIONER

Kim, Leo & D���Amore, Patricia, ASIP Centennial Commentary ��� A Brief History of Anti-VEGF for the Treatment of Ocular Angiogenesis, The American Journal of Pathology, August 2012 182(2):376-379

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J.S. Penn, et al. Vascular Endothelial Growth Factor in Eye Disease, Prog. Retin Eye Res., July 2008, 27(4):331-371. (���Penn2008���)

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U.S. Food and Drug Administration, Trivaris �� Highlights of the Prescribing Information, (May 2008) (���Trivaris label���)

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Internet Archive WayBack Machine, May 17, 2011 Record of U.S. Pharmacopeia, Understanding USP���NF

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Christine I. Falkner-Radler, et al. Needle Size in Intravitreal Injections-Preliminary Results of a Randomized Clinical Trial, AVRO Annual Meeting Abstract, March 2012, 54(884)

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Curriculum Vitae of James L. Mullins, Ph.D.

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DUPONT��� TYVEK�� COMPLIANCE TO ISO 11607-1:2006 (2011)

Apr 16, 2021EXHIBITPETITIONER

Center for Drug Evaluation and Research, Application Number: 21-756, Approved Labeling, Macugen�� (pegaptanib sodium injection) (December 17, 2004) (���2004 Macugen Label���)

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Evangelos S. Gragoudas, et al. Pegaptanib for Neovascular Age-Related Macular Degeneration, New England Journal of Medicine 2004; 351:2805-16, with Supplementary Appendix.

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IPR2020-1317, Paper No. 15, Institution Decision

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Australian Government, Department of Health and Ageing, Australian Public Assessment Report for Aflibercept, (July 2012), part 1

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Australian Government, Department of Health and Ageing, Australian Public Assessment Report for Aflibercept, (July 2012), part 2

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Sophie J. Bakri and Noha S. Ekdawi, Intravitreal Silicone Oil Droplets after Intravitreal Drug Injections, Retina 2008; 20:996-1001

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Jared S. Bee, et al. Effects of Surfaces and Leachables on the Stability of Biopharmaceuticals, Journal of Pharmaceutical Science (Oct. 2011)

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Michael Colucciello, Prefilled Syringe Delivery of Intravitreal Anti-VEGF Medications: Advantages for Patients and Physicians, Retinal Physician (Mar. 1, 2019)

Apr 16, 2021EXHIBITPETITIONER

Declaration of Juergen Sigg (���Sigg Declaration���)

Apr 16, 2021EXHIBITPETITIONER

Department of Health & Human Services, Macugen Approval Letter (Dec. 18, 2004)

Apr 16, 2021EXHIBITPETITIONER

Lonny Wolgemuth, Challenges with Prefilled Syringes: The Parylene Solution, ONdrugDelivery (Oct. 2012)

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Therese M. Sassalos, Prefilled Syringes for Intravitreal Drug Delivery, Clinical Ophthalmology 2019:13 701-706

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SCS Coating Systems, SCS Parylene Properties (2007)

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Lonny Wolgemuth, Assessing the Effects of Sterilization Methods on Parylene Coating, Medical Device & Diagnostic Industry, (Aug. 2002)

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David E. Overcashier, et al. Technical Considerations in the Development of Pre-filled Syringes for Protein Products, Am. Pharm. Rev. 2006;9(7): 77-83 (���Overcashier���)

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SDNY 20-5502 Docket

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Federal Court Statistics

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Novartis Letter to NDNY Court

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Mehmet S. Kocabora, et al. Intravitreal Silicone Oil Droplets Following Pegaptanib Injection, Acta Ophthalmologica 2010

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Macugen Label (2008)

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U.S. Pharmacopeia, USP 789, Particulate Matter in Ophthalmic Solutions, USP 32 NF 27 (2009)

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Novartis NDNY Complaint

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Novartis Letter to SDNY Court

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ITC Investigation No. 337-TA-1207, Statement on the Public Interest by Proposed Respondent Regeneron Pharmaceuticals, Inc.

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ITC Investigation No. 337-TA-1207, Statement on the Public Interest by Szilard Kiss

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Nitin Rathore, et al. Variability in Syringe Components and its Impact on Functionality of Delivery Systems, PDA Journal of Pharmaceutical Science and Technology 2011, 65 468-480 (���Rathore���)

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PCT Patent Publication No. WO 2007/084765 to Deschatelets et al.

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PCT Patent Publication No. WO 97/44068 to Tack et al.

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