The detailed information for PTAB case with proceeding number IPR2021-00881 filed by Mylan Pharmaceuticals Inc. et al. against Regeneron Pharmaceuticals, Inc. on May 5, 2021. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Case Details

Proceeding Number
IPR2021-00881
Filing Date
May 5, 2021
Petitioner
Mylan Pharmaceuticals Inc. et al.
Respondent
Regeneron Pharmaceuticals, Inc.
Status
Final Written Decision
Respondent Application Number
13940370
Respondent Tech Center
1600
Respondent Patent Number
9254338
Institution Decision Date
Nov 10, 2021
Termination Date
Nov 9, 2022

Proceeding Documents

The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.


Document NameFiling DateCategoryFiling Party

Alert me when new update on this case

Other: Fed Circuit mandate

Jul 19, 2024PAPERBOARD

Patent Owner's Notice of Appeal

Jan 10, 2023PAPERPATENT OWNER

Petitioner's Amended Mandatory Notices

Dec 29, 2022PAPERPETITIONER

Ex. 3002

Nov 9, 2022EXHIBITBOARD

Final Written Decision: original

Nov 9, 2022PAPERBOARD

Other: Hearing transcript

Oct 26, 2022PAPERBOARD

Ex. 2286 - Supplemental Declaration of Doris Weber

Oct 14, 2022EXHIBITPATENT OWNER

Petitioner's Amended Mandatory Notices

Sep 29, 2022PAPERPETITIONER

Petitioner's Amended Mandatory Notices

Aug 23, 2022PAPERPETITIONER

Petitioner's Updated Exhibit List

Aug 9, 2022PAPERPETITIONER

Petitioner's Corrected Demonstratives for Oral Argument

Aug 9, 2022EXHIBITPETITIONER

Petitioner's Updated Exhibit List

Aug 5, 2022PAPERPETITIONER

Petitioner's Demonstratives for Oral Argument (IPR2021-00881)

Aug 5, 2022EXHIBITPETITIONER

Patent Owner's Demonstratives for Oral Argument

Aug 5, 2022EXHIBITPATENT OWNER

Patent Owner's Updated Exhibit List

Aug 5, 2022PAPERPATENT OWNER

Patent Owner's Reply on Motion to Exclude Evidence

Aug 2, 2022PAPERPATENT OWNER

Petitioner's Reply to Patent Owner's Opposition to Petitioner's Motion to Exclude

Aug 2, 2022PAPERPETITIONER

Petitioner's Opposition to Patent Owner's Motion to Exclude

Jul 27, 2022PAPERPETITIONER

Patent Owner's Opposition to Petitioner's Motion to Exclude Evidence

Jul 27, 2022PAPERPATENT OWNER

Petitioner's Motion to Seal

Jul 20, 2022PAPERPETITIONER

Petitioner's Motion to Exclude Evidence CONFIDENTIAL

Jul 20, 2022PAPERPETITIONER

Petitioner's Motion to Exclude Evidence REDACTED

Jul 20, 2022PAPERPETITIONER

Patent Owner's Motion to Exclude

Jul 20, 2022PAPERPATENT OWNER

Petitioner's Amended Mandatory Notices

Jul 18, 2022PAPERPETITIONER

Order: Granting Request for Oral Hearing

Jul 15, 2022PAPERBOARD

ORDER Granting Patent Owner's Unopposed Motions for Entry of Default Protective Order and to Seal and Petitioner's Motion to Seal

Jul 13, 2022PAPERBOARD

Petitioner's Request for Oral Argument

Jul 8, 2022PAPERPETITIONER

Patent Owner's Request for Oral Argument

Jul 8, 2022PAPERPATENT OWNER

Patent Owner's Sur-Reply

Jul 6, 2022PAPERPATENT OWNER

Thomas Albini Deposition Transcript

Jul 6, 2022EXHIBITPATENT OWNER

Mary Gerritsen Deposition Transcript

Jul 6, 2022EXHIBITPATENT OWNER

CONFIDENTIAL Ivan Hofmann Deposition Transcript

Jul 6, 2022EXHIBITPATENT OWNER

PUBLIC Ivan Hofmann Deposition Transcript, part 1 of 3

Jul 6, 2022EXHIBITPATENT OWNER

PUBLIC Ivan Hofmann Deposition Transcript, part 2 of 3

Jul 6, 2022EXHIBITPATENT OWNER

PUBLIC Ivan Hofmann Deposition Transcript, part 3 of 3

Jul 6, 2022EXHIBITPATENT OWNER

Patent Owner's Motion to Seal

Jul 6, 2022PAPERPATENT OWNER

Order: Granting Petitioners Unopposed Motions for Admission pro hac vice of Robert Cerwinski, Brigid Morris, and Aviv Zalcenstein

Jun 27, 2022PAPERBOARD

Patent Owner's Notice of Deposition of Dr. Thomas A. Albini

Jun 21, 2022PAPERPATENT OWNER

Patent Owner's Notice of Deposition of Ivan T. Hofmann

Jun 20, 2022PAPERPATENT OWNER

PETITIONER CELLTRION, INC. UNOPPOSED MOTION FOR PRO HAC VICE ADMISSION OF ROBERT CERWINSKI UNDER 37 C.F.R. § 42.10(c)

Jun 6, 2022PAPERPETITIONER

PETITIONER CELLTRION, INC. UNOPPOSED MOTION FOR PRO HAC VICE ADMISSION OF BRIGID MORRIS UNDER 37 C.F.R. § 42.10(c)

Jun 6, 2022PAPERPETITIONER

PETITIONER CELLTRION, INC. UNOPPOSED MOTION FOR PRO HAC VICE ADMISSION OF AVIV ZALCENSTEIN UNDER 37 C.F.R. § 42.10(c)

Jun 6, 2022PAPERPETITIONER

Patent Owner's Second Set of Objections to Petitioner's Exhibits

Jun 6, 2022PAPERPATENT OWNER

Patent Owner's Corrected Second Set of Objections to Petitioner's Exhibits

Jun 6, 2022PAPERPATENT OWNER

Patent Owner's Notice of Deposition of Mary E. Gerritsen, Ph.D.

Jun 6, 2022PAPERPATENT OWNER

Petitioner Celltrion's Updated Exhibit List

May 31, 2022PAPERPETITIONER

Declaration of Robert V. Cerwinski ISO Motion for Pro Hac Vice Admission

May 31, 2022EXHIBITPETITIONER

Declaration of Aviv A. Zalcenstein ISO Motion for Pro Hac Vice Admission

May 31, 2022EXHIBITPETITIONER

Declaration of Brigid M. Morris ISO Motion for Pro Hac Vice Admission

May 31, 2022EXHIBITPETITIONER

Petitioner's Motion to Seal (5-27-22)

May 27, 2022PAPERPETITIONER

Ex. 1102 - '959 FH, 12-22-2011 PTE

May 27, 2022EXHIBITPETITIONER

Ex. 1103 - Klibanov Dep. Ex. 3, Klibanov Amgen Decl.

May 27, 2022EXHIBITPETITIONER

Ex. 1104 - Klibanov Dep. Ex. 18, Hanhart

May 27, 2022EXHIBITPETITIONER

Ex. 1105 - Klibanov Dep. Ex. 19, Stefanini

May 27, 2022EXHIBITPETITIONER

Ex. 1106 - Klibanov Dep. Ex. 20, Yang

May 27, 2022EXHIBITPETITIONER

Ex. 1107 - Klibanov Dep. Ex. 22, WHO Drug Info

May 27, 2022EXHIBITPETITIONER

Ex. 1108 - Klibanov Dep. Tr. CONFIDENTIAL

May 27, 2022EXHIBITPETITIONER

Ex. 1108 - Klibanov Dep. Tr. REDACTED

May 27, 2022EXHIBITPETITIONER

Ex. 1109 - Do Dep. Tr.

May 27, 2022EXHIBITPETITIONER

Ex. 1110 - Brown Dep. Tr.

May 27, 2022EXHIBITPETITIONER

Ex. 1111 - Del Priore Dep. Tr. CONFIDENTIAL

May 27, 2022EXHIBITPETITIONER

Ex. 1111 - Del Priore Dep. Tr. REDACTED

May 27, 2022EXHIBITPETITIONER

Ex. 1112 - Klibanov Dep. Ex. 14, Duncan

May 27, 2022EXHIBITPETITIONER

Ex. 1113 - Del Priore Dep. Ex. 10, Rudge 2008

May 27, 2022EXHIBITPETITIONER

Ex. 1114 - Albini Reply Decl.

May 27, 2022EXHIBITPETITIONER

Ex. 1115 - Gerritsen Reply Decl.

May 27, 2022EXHIBITPETITIONER

Ex. 1116 - Transcript (19-May-2022)

May 27, 2022EXHIBITPETITIONER

Ex. 1117 - Klibanov Dep. Ex. 6, ���173 patent SEQ. ID No 2

May 27, 2022EXHIBITPETITIONER

Ex. 1118 - Klibanov Dep. Ex. 9, CAS

May 27, 2022EXHIBITPETITIONER

Ex. 1119 - Klibanov Dep. Ex. 12, Rudge 2007

May 27, 2022EXHIBITPETITIONER

Ex. 1120 - Klibanov Dep. Ex. 13, Gomez-Manzano

May 27, 2022EXHIBITPETITIONER

Ex. 1121 - Klibanov Dep. Ex. 21, Liu

May 27, 2022EXHIBITPETITIONER

Ex. 1122 - AA Alignment

May 27, 2022EXHIBITPETITIONER

Ex. 1123 - Quiram

May 27, 2022EXHIBITPETITIONER

Ex. 1124 - NA Alignment

May 27, 2022EXHIBITPETITIONER

Ex. 1125 - HPE 2006

May 27, 2022EXHIBITPETITIONER

Ex. 1126 - Volkin & Klibanov 1992

May 27, 2022EXHIBITPETITIONER

Ex. 1127 - 959 FH, Election re PTE

May 27, 2022EXHIBITPETITIONER

Ex. 1128 - 959 FH, PTE Certificate

May 27, 2022EXHIBITPETITIONER

Ex. 1129 - Wulff

May 27, 2022EXHIBITPETITIONER

Ex. 1130 - Do Dep. Ex. 2, Regeneron (22-Nov-2019)

May 27, 2022EXHIBITPETITIONER

Ex. 1131 - Do Dep. Ex. 3, Vanderkam

May 27, 2022EXHIBITPETITIONER

Ex. 1133 - '345 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1134 - '601 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1135 - '058 publication

May 27, 2022EXHIBITPETITIONER

Ex. 1136 - Hofmann CV

May 27, 2022EXHIBITPETITIONER

Ex. 1137 - Hofmann Reply Decl. CONFIDENTIAL

May 27, 2022EXHIBITPETITIONER

Ex. 1137 - Hofmann Reply Decl. REDACTED

May 27, 2022EXHIBITPETITIONER

Ex. 1138 - Do Dep. Ex. 4, ���338 patent claim 1

May 27, 2022EXHIBITPETITIONER

Ex. 1139 - Brown Dep. Ex. 10, ASRS Clinical Update

May 27, 2022EXHIBITPETITIONER

Ex. 1140 - Brown Dep. Ex. 11, Medicare Comment Summary

May 27, 2022EXHIBITPETITIONER

Ex. 1141 - PGR20221-00035, Paper 6

May 27, 2022EXHIBITPETITIONER

Ex. 1142 - Fauser

May 27, 2022EXHIBITPETITIONER

Ex. 1143 - Do

May 27, 2022EXHIBITPETITIONER

Ex. 1144 - '563 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1145 - '653 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1146 - Drugs@FDA_ Eylea

May 27, 2022EXHIBITPETITIONER

Ex. 1147 - Regeneron 2005 10-K

May 27, 2022EXHIBITPETITIONER

Ex. 1148 - '748 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1149 - Regeneron 2011 10-K

May 27, 2022EXHIBITPETITIONER

Ex. 1150 - Weber Dep. Tr.

May 27, 2022EXHIBITPETITIONER

Ex. 1151 - Manning Dep. Tr. CONFIDENTIAL

May 27, 2022EXHIBITPETITIONER

Ex. 1151 - Manning Tr. REDACTED

May 27, 2022EXHIBITPETITIONER

Ex. 1152 - Manning Dep. Ex. 6, Eylea Label 06.2021

May 27, 2022EXHIBITPETITIONER

Ex. 1153 - Manning Dep. Ex. 7, Eylea Patent List

May 27, 2022EXHIBITPETITIONER

Ex. 1154 - 2020-06-24 Complaint

May 27, 2022EXHIBITPETITIONER

Ex. 1155 - Batta

May 27, 2022EXHIBITPETITIONER

Ex. 1156 - Eylea Label 05.2016

May 27, 2022EXHIBITPETITIONER

Ex. 1157 - '261 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1158 - '598 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1159 - '791 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1160 - '803 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1161 - '737 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1162 - '842 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1163 - '992 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1164 - '458 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1165 - '865 patent

May 27, 2022EXHIBITPETITIONER

Ex. 1166 - Purple Book List

May 27, 2022EXHIBITPETITIONER

Ex. 1167 - United Healthcare Ophthalmologic Policy, VEGF

May 27, 2022EXHIBITPETITIONER

Ex. 1168 - BCBS Florida VEGF

May 27, 2022EXHIBITPETITIONER

Ex. 1169 - Eylea Summary Review

May 27, 2022EXHIBITPETITIONER

Ex. 1170 - mygoodays.org CDF

May 27, 2022EXHIBITPETITIONER

Ex. 1171 - Official EYLEA (aflibercept) Injection Website

May 27, 2022EXHIBITPETITIONER

Ex. 1172 - Bayer and Regeneron to Collaborate on VEGF Trap

May 27, 2022EXHIBITPETITIONER

Ex. 1173 - Complaint, Horizon v Regeneron, 2022-04

May 27, 2022EXHIBITPETITIONER

Ex. 1174 - oig.hhs.gov Publication of OIG Special Fraud Alerts

May 27, 2022EXHIBITPETITIONER

Ex. 1175 - MorganLewis - New Purple Book Patent Requirements

May 27, 2022EXHIBITPETITIONER

Ex. 1176 - Dadgostar

May 27, 2022EXHIBITPETITIONER

Petitioner's Reply (CONFIDENTIAL)

May 27, 2022PAPERPETITIONER

Petitioner's Reply (REDACTED)

May 27, 2022PAPERPETITIONER

Petitioner's Amended Mandatory Notices

May 16, 2022PAPERPETITIONER

Order: Other

May 11, 2022PAPERBOARD

Petitioner's Notice of Deposition of Doris Weber

May 3, 2022PAPERPETITIONER

Petitioner's Notice of Deposition of Richard Manning Ph.D.

Apr 22, 2022PAPERPETITIONER

Petitioner's Unopposed Motion for Pro Hac Vice Admission of Eric R. Hunt

Apr 20, 2022PAPERPETITIONER

Declaration of Eric R. Hunt in Support of Petitioner's Unopposed Motion for Pro Hac Vice Admission

Apr 20, 2022EXHIBITPETITIONER

Petitioner's Updated Exhibit List

Apr 20, 2022PAPERPETITIONER

Petitioner's Updated Power of Attorney

Apr 20, 2022PAPERPETITIONER

Petitioner's Amended Mandatory Notices

Apr 20, 2022PAPERPETITIONER

Petitioner's Notice of Deposition of Lucian V. Del Priore M.D. Ph.D.

Apr 19, 2022PAPERPETITIONER

Petitioner's Notice of Deposition of David M. Brown M.D.

Apr 15, 2022PAPERPETITIONER

Petitioner's Notice of Deposition of Diana V. Do M.D.

Apr 11, 2022PAPERPETITIONER

Order: Revised Joint Scheduling Order

Mar 23, 2022PAPERBOARD

Petitioners Notice of Deposition of Alexander M. Klibanov Ph.D,

Mar 14, 2022PAPERPETITIONER

Patent Owner's Response to Petitioner's Identification of Statements Supported by Objected to References in Patent Owner Responses

Mar 3, 2022PAPERPATENT OWNER

PETITIONER'S IDENTIFICATION OF STATEMENTS SUPPORTED BY OBJECTED TO REFERENCES IN PATENT OWNER RESPONSES

Feb 28, 2022PAPERPETITIONER

Petitioner's Updated Exhibit List

Feb 28, 2022PAPERPETITIONER

Ex. 1100 - Transcript (23-February-2022)

Feb 28, 2022EXHIBITPETITIONER

Petitioner's Second Objections to Patent Owner's Exhibits

Feb 18, 2022PAPERPETITIONER

Corrected Patent Owner's Motion to Seal

Feb 14, 2022PAPERPATENT OWNER

EXPUNGED

Feb 11, 2022PAPERPATENT OWNER

Declaration of Lucian V. Del Priore, M.D., Ph.D. - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Declaration of Lucian V. Del Priore, M.D., Ph.D. - Public Version

Feb 11, 2022EXHIBITPATENT OWNER

Declaration of Alexander M. Klibanov, Ph.D. - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Declaration of Alexander M. Klibanov, Ph.D. - Public Version

Feb 11, 2022EXHIBITPATENT OWNER

Declaration of David M. Brown, M.D.

Feb 11, 2022EXHIBITPATENT OWNER

Declaration of Diana V. Do, M.D.

Feb 11, 2022EXHIBITPATENT OWNER

Declaration of Richard Manning, Ph.D. with Attachments - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Declaration of Richard Manning, Ph.D. with Attachments - Public Version

Feb 11, 2022EXHIBITPATENT OWNER

NCT00794417

Feb 11, 2022EXHIBITPATENT OWNER

NCT01148615

Feb 11, 2022EXHIBITPATENT OWNER

Ferrara 2006

Feb 11, 2022EXHIBITPATENT OWNER

Kim 2012

Feb 11, 2022EXHIBITPATENT OWNER

Ramazi 2021

Feb 11, 2022EXHIBITPATENT OWNER

Bork 2009

Feb 11, 2022EXHIBITPATENT OWNER

Koehler-Stec Report - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

VGFT-OD-0605 Analysis Summary - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Kim 2021

Feb 11, 2022EXHIBITPATENT OWNER

Nieto 2013

Feb 11, 2022EXHIBITPATENT OWNER

Fernandez-Ferreiro 2017

Feb 11, 2022EXHIBITPATENT OWNER

Shen 2007

Feb 11, 2022EXHIBITPATENT OWNER

Cobo 1981

Feb 11, 2022EXHIBITPATENT OWNER

Pflugfelder 1987

Feb 11, 2022EXHIBITPATENT OWNER

Hirokawa 1988

Feb 11, 2022EXHIBITPATENT OWNER

Prange 1998

Feb 11, 2022EXHIBITPATENT OWNER

Kleiger 2000

Feb 11, 2022EXHIBITPATENT OWNER

Demarest 2004

Feb 11, 2022EXHIBITPATENT OWNER

Kuhlmann 2010

Feb 11, 2022EXHIBITPATENT OWNER

Murphy 2006

Feb 11, 2022EXHIBITPATENT OWNER

Zaltrap non-comparability - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Sola 2009

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Approval Letter

Feb 11, 2022EXHIBITPATENT OWNER

Cantu 2010

Feb 11, 2022EXHIBITPATENT OWNER

Chen 2016

Feb 11, 2022EXHIBITPATENT OWNER

NCT00519285

Feb 11, 2022EXHIBITPATENT OWNER

NCT00644124

Feb 11, 2022EXHIBITPATENT OWNER

Heier Retinal Physician 2009

Feb 11, 2022EXHIBITPATENT OWNER

CV of Lucian V. Del Priore, M.D., Ph.D.

Feb 11, 2022EXHIBITPATENT OWNER

CV of Alexander M. Klibanov, Ph.D.

Feb 11, 2022EXHIBITPATENT OWNER

CV of David M. Brown, M.D.

Feb 11, 2022EXHIBITPATENT OWNER

Adamis Chapter 4

Feb 11, 2022EXHIBITPATENT OWNER

Brown 2009

Feb 11, 2022EXHIBITPATENT OWNER

Regillo 2008

Feb 11, 2022EXHIBITPATENT OWNER

Abraham 2010

Feb 11, 2022EXHIBITPATENT OWNER

Barbazetto 2010

Feb 11, 2022EXHIBITPATENT OWNER

Cruz 2006

Feb 11, 2022EXHIBITPATENT OWNER

Retinal Physician Symposium

Feb 11, 2022EXHIBITPATENT OWNER

Lucentis Label 2006

Feb 11, 2022EXHIBITPATENT OWNER

Schmidt-Erfuth 2011

Feb 11, 2022EXHIBITPATENT OWNER

Margolis 2010

Feb 11, 2022EXHIBITPATENT OWNER

Brown 2011

Feb 11, 2022EXHIBITPATENT OWNER

Heier 2011

Feb 11, 2022EXHIBITPATENT OWNER

Research Agreement - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

FDA Non-Inferiority Clinical Trials

Feb 11, 2022EXHIBITPATENT OWNER

CDER Statistical Review

Feb 11, 2022EXHIBITPATENT OWNER

FDA 22 Case Studies

Feb 11, 2022EXHIBITPATENT OWNER

Heier 2005

Feb 11, 2022EXHIBITPATENT OWNER

NCT00320788

Feb 11, 2022EXHIBITPATENT OWNER

Wells 2015

Feb 11, 2022EXHIBITPATENT OWNER

Retinal Physician - Ongoing Treatment

Feb 11, 2022EXHIBITPATENT OWNER

Mathis 2009

Feb 11, 2022EXHIBITPATENT OWNER

Cousins 2010

Feb 11, 2022EXHIBITPATENT OWNER

Helzner 2007

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Press Release Nov. 18, 2011

Feb 11, 2022EXHIBITPATENT OWNER

FDA Expedited Programs

Feb 11, 2022EXHIBITPATENT OWNER

NCT01486771

Feb 11, 2022EXHIBITPATENT OWNER

Gallemore 2008

Feb 11, 2022EXHIBITPATENT OWNER

Kanghong Press Release - Chinese

Feb 11, 2022EXHIBITPATENT OWNER

Kanghong Press Release - English Translation

Feb 11, 2022EXHIBITPATENT OWNER

Thomas 2013

Feb 11, 2022EXHIBITPATENT OWNER

Ohr 2012

Feb 11, 2022EXHIBITPATENT OWNER

FDA Approves Eylea for Wet AMD

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Corrected Press Release Nov. 18, 2011

Feb 11, 2022EXHIBITPATENT OWNER

Macugen Approval Letter

Feb 11, 2022EXHIBITPATENT OWNER

Brown 2006

Feb 11, 2022EXHIBITPATENT OWNER

Rosenfeld 2006

Feb 11, 2022EXHIBITPATENT OWNER

Genentech Press Release Dec. 30, 2005

Feb 11, 2022EXHIBITPATENT OWNER

Genentech Press Release June 30, 2006

Feb 11, 2022EXHIBITPATENT OWNER

NCT00473330

Feb 11, 2022EXHIBITPATENT OWNER

NCT00473382

Feb 11, 2022EXHIBITPATENT OWNER

NCT00486018

Feb 11, 2022EXHIBITPATENT OWNER

NCT00485836

Feb 11, 2022EXHIBITPATENT OWNER

NCT00943072

Feb 11, 2022EXHIBITPATENT OWNER

NCT01012973

Feb 11, 2022EXHIBITPATENT OWNER

VGFT-OD-0605 Protocol Signature Page - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Transcript of Deposition of Mary Gerritsen Ph.D., Jan. 14, 2022

Feb 11, 2022EXHIBITPATENT OWNER

Transcript of Deposition of Thomas Albini M.D., Jan. 20, 2022

Feb 11, 2022EXHIBITPATENT OWNER

Brown 2013

Feb 11, 2022EXHIBITPATENT OWNER

Albini Deposition Exhibit 14

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Earnings Call Transcript, Feb. 13, 2012

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Earnings Call Transcript, Apr. 26, 2012

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Earnings Call Transcript, July 25, 2012

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Marketing Material, 2013

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Marketing Material, Nov. 2013 part 1 of 2

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Marketing Material Nov. 2013 part 2 of 2

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Physician ATU Wave 2 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron For the Treatment of Wet AMD, 2012

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Physician ATU Wave 5 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Am. Acad. of Ophthalmol. - Anti-VEGF Treatments

Feb 11, 2022EXHIBITPATENT OWNER

Am. Acad. of Ophthalmol. - Bevacizumab

Feb 11, 2022EXHIBITPATENT OWNER

Am. Acad. of Ophthalmol. - Ophthalmology Subspecialists

Feb 11, 2022EXHIBITPATENT OWNER

Am. Acad. of Ophthalmol. - Retinal Vasculitis

Feb 11, 2022EXHIBITPATENT OWNER

Am. Acad. of Ophthalmol. - What Is Avastin

Feb 11, 2022EXHIBITPATENT OWNER

Am. Acad. of Ophthalmol. - What Is Eylea

Feb 11, 2022EXHIBITPATENT OWNER

Am. Acad. of Ophthalmol. - What Is Lucentis

Feb 11, 2022EXHIBITPATENT OWNER

Am. Soc. of Retina Specialists - About Us

Feb 11, 2022EXHIBITPATENT OWNER

Am. Soc. of Retina Specialists - Age-Related Macular Degeneration

Feb 11, 2022EXHIBITPATENT OWNER

Am. Soc. of Retina Specialists - Branch Retinal Vein Occlusion

Feb 11, 2022EXHIBITPATENT OWNER

Am. Soc. of Retina Specialists - Central Retinal Vein Occlusion

Feb 11, 2022EXHIBITPATENT OWNER

Am. Soc. of Retina Specialists - Diabetic Retinopathy

Feb 11, 2022EXHIBITPATENT OWNER

Amgen - Fusion Protein

Feb 11, 2022EXHIBITPATENT OWNER

ASHA - Calculating Medicare Fee Schedule Rates

Feb 11, 2022EXHIBITPATENT OWNER

ASPE Issue Brief - Medicare Part B Reimbursement of Prescription Drugs

Feb 11, 2022EXHIBITPATENT OWNER

Avastin Drug Label 2004

Feb 11, 2022EXHIBITPATENT OWNER

Base Pair Biotechnologies - What is an Aptamer

Feb 11, 2022EXHIBITPATENT OWNER

Bausch and Lomb Website - Visudyne

Feb 11, 2022EXHIBITPATENT OWNER

Bausch and Lomb Website - Visudyne Saftey Information

Feb 11, 2022EXHIBITPATENT OWNER

Bausch Health Companies 10-K, 2020

Feb 11, 2022EXHIBITPATENT OWNER

Beovu Drug Label Oct. 2019

Feb 11, 2022EXHIBITPATENT OWNER

Beovu Drug Label June 2020

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Physician ATU Wave 4 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

BrightFocus Foundation - AMD Facts & Figures

Feb 11, 2022EXHIBITPATENT OWNER

Brookings - Medicare Payment for Physician-Administered (Part B) Drugs

Feb 11, 2022EXHIBITPATENT OWNER

Calculator.net - Sample Size Calculator

Feb 11, 2022EXHIBITPATENT OWNER

CDC - Vision Loss - A Public Health Problem

Feb 11, 2022EXHIBITPATENT OWNER

Centers for Medicare & Medicaid Services Data - Practitioners

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Sample Disbursement part 1 of 6 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Sample Disbursement part 2 of 6 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Sample Disbursement part 3 of 6 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Sample Disbursement part 4 of 6 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Sample Disbursement part 5 of 6 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Sample Disbursement part 6 of 6 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

US Eylea P&L - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

US Eylea P&L - Public Version

Feb 11, 2022EXHIBITPATENT OWNER

CloudResearch - Determining Sample Size

Feb 11, 2022EXHIBITPATENT OWNER

CMS - 2021 ASP Drug Pricing Files

Feb 11, 2022EXHIBITPATENT OWNER

CMS - Medicare Part B Drug Average Sales Price

Feb 11, 2022EXHIBITPATENT OWNER

CMS - Physician Fee Schedule

Feb 11, 2022EXHIBITPATENT OWNER

CMS Medicare Coverage Database - Billing and Coding Afilbercept

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Q4 Performance Update - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Donahue 2007

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Donohue 2004

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Dreyfuss 2015

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Miller 2020

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Drugs.com - Eylea FDA Approval History

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Elyasi 2021

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Eye Care Surgery Center - Macular Degeneration

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EyeGuru - Intravitreal Injection Standard Dosing Table

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Eylea Drug Label Nov. 2011

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Eylea Drug Label Sept. 2012

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Eylea Drug Label Oct. 2014

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FiercePharma - Novartis Drug Beovu Tied to Potential Vision Loss

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FiercePharma - The top 20 drugs by worldwide sales in 2020

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FocusVision - Survey Sample Size How Much Do I Need

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Gagnon 2008

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Eylea Physician ATU Benchmark Wave - Confidential

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GEN - FDA Green-Lights Genentechs Lucentis

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Genentech Press Release June 30, 2006

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Regeneron US Eylea Historical PL - Confidential

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Regeneron US Eylea Historical PL - Confidential

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Regeneron US Eylea Historical PL - Public

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Guha 2009

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HCPCS Codes - HCPCS Codes

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Healio - Access to retina providers shows no geographic bias in US

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Hopkins Medicine Website - Photodynamic Therapy for AMD

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Eylea DME Market Assessment - Confidential

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IQVIA 10-K 2020

Feb 11, 2022EXHIBITPATENT OWNER

IQVIA - Available IQVIA Data

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Eylea ATU Wave 2 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

KFF - Snapshot of Sources of Coverage

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KFF - Medicare Advantage in 2021

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Ling 2002

Feb 11, 2022EXHIBITPATENT OWNER

Lucentis Drug Label 2006

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Lucentis Drug Label June 2010

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Lucentis Drug Label Aug. 2012

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Lucentis Drug Label Apr. 2017

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Lucentis Drug Label Mar. 2018

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Macugen Drug Label Dec. 2004

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Eylea Components of Reimbursement - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Components of Reimbursement - Public

Feb 11, 2022EXHIBITPATENT OWNER

Mankiw Chapter 1

Feb 11, 2022EXHIBITPATENT OWNER

Manning 2015

Feb 11, 2022EXHIBITPATENT OWNER

Mayo Clinic - Wet macular degeneration - Diagnosis and treatment

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Mayo Clinic - Wet macular degeneration - Symptoms and Causes

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Medicare Interactive - Medicare Part B Covered Services

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Medicare Interactive - The parts of Medicare

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Medicare.gov - Macular Degeneration Coverage

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Medicare.gov - Medicare Advantage Plans

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Medicare.gov - When does Medicare coverage start

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MedlinePlus Medical Encyclopedia - Laser photocoagulation

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Regeneron WAC Pricing - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Novartis - Annual Report, 2020

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Novartis Press Release Oct. 8, 2019

Feb 11, 2022EXHIBITPATENT OWNER

Novartis Press Release June 11, 2020

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Oct 12 ASP Pricing File revised 060513

Feb 11, 2022EXHIBITPATENT OWNER

Oct 13 ASP Pricing File updated 060614

Feb 11, 2022EXHIBITPATENT OWNER

Oct 15 ASP Pricing File - updated 120915

Feb 11, 2022EXHIBITPATENT OWNER

Oct 16 ASP Pricing File updated 082817

Feb 11, 2022EXHIBITPATENT OWNER

Oct 17 ASP Pricing File 083017

Feb 11, 2022EXHIBITPATENT OWNER

Oct 18 ASP Pricing File updated 052919

Feb 11, 2022EXHIBITPATENT OWNER

Oct 2019 ASP Pricing File 052920

Feb 11, 2022EXHIBITPATENT OWNER

Oct 14 ASP Pricing File - revised 090115

Feb 11, 2022EXHIBITPATENT OWNER

October 2020 ASP Pricing File updated 090121

Feb 11, 2022EXHIBITPATENT OWNER

October 2021 ASP Pricing File updated 011022

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ASRS Preferences & Trends Survey 2016 - Confidential

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ASRS Preferences & Trends Survey 2015 - Confidential

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Pindyck Chapter 3

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Regeneron - About Us

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Press Release July 29, 2014

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Press Release Oct. 6, 2014

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Press Release May 13, 2019

Feb 11, 2022EXHIBITPATENT OWNER

ASRS Preferences & Trends Survey 2014 part 1 of 2 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

ASRS Preferences & Trends Survey 2014 part 2 of 2 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron - History

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Press Release Sept. 21, 2012

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron - Research Areas

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Form 10-K for 2020 part 1 of 2

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Form 10-K for 2020 part 2 of 2

Feb 11, 2022EXHIBITPATENT OWNER

Retinal Physician - Revisiting an Early Treatment for Wet AMD

Feb 11, 2022EXHIBITPATENT OWNER

Roche 10-K, 2020

Feb 11, 2022EXHIBITPATENT OWNER

Roche Press Release Aug. 13, 2012

Feb 11, 2022EXHIBITPATENT OWNER

Roche Press Release Apr. 18, 2017

Feb 11, 2022EXHIBITPATENT OWNER

ASRS Preferences & Trends Survey 2009 - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Schweitzer Chapter 4

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ScienceDaily - FDA Approves First Angiogenesis Inhibitor

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Sivaprasad 2021

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Sales Summary - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Verywell Health - Maclular Degeneration Timeline

Feb 11, 2022EXHIBITPATENT OWNER

Vestrum Health - Explore what we can do for you

Feb 11, 2022EXHIBITPATENT OWNER

Vestrum Health - Pharmaceutical companies

Feb 11, 2022EXHIBITPATENT OWNER

Visudyne Drug Label Apr. 2016

Feb 11, 2022EXHIBITPATENT OWNER

Weidner 2021

Feb 11, 2022EXHIBITPATENT OWNER

WHO - Blindness and vision impairment

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Yahoo Finance - Beovu Now Publicly Reimbursed

Feb 11, 2022EXHIBITPATENT OWNER

Yorston 2014

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Q2 2021 Performance - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Vestrum Anti-VEGF Category Sales Shares - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Wet AMD Line of Therapy Insights - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Vestrum Anti-VEGF Market Share Adjustment - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Q2 2020 Performance - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Marketing Planning Process - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron Wave 1 2021 Performance Update - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron ATU Sales Share Data - All Indications

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron ATU Sales Share Data - Wet AMD

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron ATU Sales Share Data - DME

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron ATU Sales Share Data - CRVO

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron ATU Sales Share Data - BRVO

Feb 11, 2022EXHIBITPATENT OWNER

Regeneron ATU Sales Share Data - DR without DME

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Gross & Net Sales P&L - Confidential

Feb 11, 2022EXHIBITPATENT OWNER

Eylea Gross & Net Sales P&L - Public

Feb 11, 2022EXHIBITPATENT OWNER

EXPUNGED

Feb 11, 2022PAPERPATENT OWNER

EXPUNGED

Feb 11, 2022PAPERPATENT OWNER

Corrected Patent Owner Response - Confidential

Feb 11, 2022PAPERPATENT OWNER

Corrected Patent Owner Response - Public

Feb 11, 2022PAPERPATENT OWNER

Other: DECISION Granting Institution of Inter Partes Review Granting Motion for Joinder

Feb 9, 2022PAPERBOARD

Other: DECISION Granting Institution of Inter Partes Review Granting Motion for Joinder

Feb 9, 2022PAPERBOARD

EXPUNGED

Feb 7, 2022EXHIBITBOARD

Patent Owner's Unopposed Motion for Entry of Default Protective Order

Feb 3, 2022PAPERPATENT OWNER

Notice of Stipulated Schedule

Dec 9, 2021PAPERPATENT OWNER

Granting Patent Owners Unopposed Motions for Admission pro hac vice of Victoria Reines, Daniel Reisner, Matthew M. Wilk, and Jeremy Cobb 37 C.F.R. sec 42.10

Dec 9, 2021PAPERBOARD

Petitioner's Objections to Patent Owner's Exhibits

Nov 26, 2021PAPERPETITIONER

Patent Owner's Objections to Petitioner's Exhibits

Nov 24, 2021PAPERPATENT OWNER

Patent Owner's Power of Attorney

Nov 22, 2021PAPERPATENT OWNER

Patent Owner's Updated Mandatory Notices

Nov 22, 2021PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

Nov 22, 2021PAPERPATENT OWNER

Pro Hac Vice Motion to Admit Victoria Reines

Nov 22, 2021PAPERPATENT OWNER

Declaration of Victoria Reines

Nov 22, 2021EXHIBITPATENT OWNER

Pro Hac Vice Motion to Admit Daniel Reisner

Nov 22, 2021PAPERPATENT OWNER

Declaration of Daniel Reisner

Nov 22, 2021EXHIBITPATENT OWNER

Pro Hac Vice Motion to Admit Matthew M. Wilk

Nov 22, 2021PAPERPATENT OWNER

Declaration of Matthew M. Wilk

Nov 22, 2021EXHIBITPATENT OWNER

Pro Hac Vice Motion to Admit Jeremy Cobb

Nov 22, 2021PAPERPATENT OWNER

Declaration of Jeremy Cobb

Nov 22, 2021EXHIBITPATENT OWNER

Order: JOINT SCHEDULING ORDER

Nov 12, 2021PAPERBOARD

Institution Decision: Grant

Nov 10, 2021PAPERBOARD

Patent Owner's Consolidated Sur-reply to Reply to Preliminary Response

Oct 6, 2021PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

Oct 6, 2021PAPERPATENT OWNER

Thomson Reuters Press Release

Oct 6, 2021EXHIBITPATENT OWNER

Petitioner's Amended Mandatory Notices

Oct 1, 2021PAPERPETITIONER

Mylan Reply to POPR

Sep 29, 2021PAPERPETITIONER

Petitioner���s Updated Exhibit List

Sep 29, 2021PAPERPETITIONER

Ex.1098 - Redline Compare

Sep 29, 2021EXHIBITPETITIONER

Ex.1099 - 597 FH Excerpts (NXP)

Sep 29, 2021EXHIBITPETITIONER

Patent Owner's Updated Mandatory Notices

Sep 24, 2021PAPERPATENT OWNER

Order: Additional Briefing

Sep 22, 2021PAPERBOARD

Order: on Motion

Sep 22, 2021PAPERBOARD

Mylan Pharmaceuticals Inc.���s Unopposed Motion to Amend Its Mandatory Notices

Sep 14, 2021PAPERPETITIONER

Petitioner's Updated Exhibit List

Sep 10, 2021PAPERPETITIONER

Ex. 1097 - Transcript (8-September-2021)

Sep 10, 2021EXHIBITPETITIONER

Expert Declaration of Dr. Diana V. Do, M.D.

Aug 16, 2021EXHIBITPATENT OWNER

Curriculum Vitae of Dr. Diana Do

Aug 16, 2021EXHIBITPATENT OWNER

Lucentis (ranibzumab injection) label, revised June 2010

Aug 16, 2021EXHIBITPATENT OWNER

Tender Offer to Momenta

Aug 16, 2021EXHIBITPATENT OWNER

Press Release, Aug. 19, 2020

Aug 16, 2021EXHIBITPATENT OWNER

Press Release, Oct. 1, 2020

Aug 16, 2021EXHIBITPATENT OWNER

Press Release, Sept. 28, 2008

Aug 16, 2021EXHIBITPATENT OWNER

NCT00637337

Aug 16, 2021EXHIBITPATENT OWNER

US Patent App. Pub. 2006/0058234 A1

Aug 16, 2021EXHIBITPATENT OWNER

Excerpts from Biochemistry 5th Ed.

Aug 16, 2021EXHIBITPATENT OWNER

Stewart & Rosenfeld 2008

Aug 16, 2021EXHIBITPATENT OWNER

Iacono 2010

Aug 16, 2021EXHIBITPATENT OWNER

Do 2009

Aug 16, 2021EXHIBITPATENT OWNER

Mononey 2009

Aug 16, 2021EXHIBITPATENT OWNER

US Patent App. Pub. 2010/0160233 A1

Aug 16, 2021EXHIBITPATENT OWNER

Hachiya 2007

Aug 16, 2021EXHIBITPATENT OWNER

Piques 2009

Aug 16, 2021EXHIBITPATENT OWNER

Jaffe 2016

Aug 16, 2021EXHIBITPATENT OWNER

Eylea (aflibercept) Injection label, revised May 2016

Aug 16, 2021EXHIBITPATENT OWNER

NCT02247531

Aug 16, 2021EXHIBITPATENT OWNER

NCT02247479

Aug 16, 2021EXHIBITPATENT OWNER

NCT03630952

Aug 16, 2021EXHIBITPATENT OWNER

NCT03577899

Aug 16, 2021EXHIBITPATENT OWNER

NCT01944839

Aug 16, 2021EXHIBITPATENT OWNER

NCT01940900

Aug 16, 2021EXHIBITPATENT OWNER

BiopharmaDive article, Aug. 14, 2017

Aug 16, 2021EXHIBITPATENT OWNER

Li 2014

Aug 16, 2021EXHIBITPATENT OWNER

Presentation, Sept. 30, 2007

Aug 16, 2021EXHIBITPATENT OWNER

Bhisitkul & Stewart 2010

Aug 16, 2021EXHIBITPATENT OWNER

Park 2012

Aug 16, 2021EXHIBITPATENT OWNER

Spaide 2007

Aug 16, 2021EXHIBITPATENT OWNER

Boyer 2009

Aug 16, 2021EXHIBITPATENT OWNER

Lucentis (ranibzumab injection) label, revised March 2018

Aug 16, 2021EXHIBITPATENT OWNER

US Patent 7,303,746

Aug 16, 2021EXHIBITPATENT OWNER

US Patent 7,521,049

Aug 16, 2021EXHIBITPATENT OWNER

US Patent 7,303,747

Aug 16, 2021EXHIBITPATENT OWNER

US Patent 7,306,799

Aug 16, 2021EXHIBITPATENT OWNER

Macugen (pegaptanib sodium injection) label

Aug 16, 2021EXHIBITPATENT OWNER

Press Release, Feb. 14, 2013

Aug 16, 2021EXHIBITPATENT OWNER

Press Release, Feb. 6, 2020

Aug 16, 2021EXHIBITPATENT OWNER

Press Release, Dec. 20, 2010

Aug 16, 2021EXHIBITPATENT OWNER

Levine 2009

Aug 16, 2021EXHIBITPATENT OWNER

Preliminary Response of Patent Owner Regeneron Pharmaceuticals, Inc.

Aug 16, 2021PAPERPATENT OWNER

DECISION Granting Petitioners Motions for Admission pro hac vice of William A. Rakoczy and Heinz J. Salmen 37 C.F.R. sec 42.10

Jul 22, 2021PAPERBOARD

Mylan Pharmaceuticals Inc.���s Unopposed Motion For Pro Hac Vice Admission Of William A. Rakoczy

Jun 18, 2021PAPERPETITIONER

Ex.1095 - WAR Declaration (PHV Admission) - 338 petition (6-18-21)

Jun 18, 2021EXHIBITPETITIONER

Mylan Pharmaceuticals Inc.���s Unopposed Motion For Pro Hac Vice Admission Of Heinz J. Salmen

Jun 18, 2021PAPERPETITIONER

Ex.1096 - HJS Declaration (PHV Admission) - 338 petition (6-18-21)

Jun 18, 2021EXHIBITPETITIONER

Petitioner���s Exhibit List - 338 petition (6-18-21)

Jun 18, 2021PAPERPETITIONER

Patent Owner's Power of Attorney

May 24, 2021PAPERPATENT OWNER

Patent Owner's Mandatory Notices

May 24, 2021PAPERPATENT OWNER

Notice of Accord Filing Date

May 14, 2021PAPERBOARD

Ex.1001 - 338 patent

May 5, 2021EXHIBITPETITIONER

Ex.1002 - Albini

May 5, 2021EXHIBITPETITIONER

Ex.1003 - Gerritsen

May 5, 2021EXHIBITPETITIONER

Ex.1004 - Holash

May 5, 2021EXHIBITPETITIONER

Ex.1005 - Nguyen-2009

May 5, 2021EXHIBITPETITIONER

Ex.1006 - Dixon

May 5, 2021EXHIBITPETITIONER

Ex.1007 - Adis

May 5, 2021EXHIBITPETITIONER

Ex.1008 - 173 patent

May 5, 2021EXHIBITPETITIONER

Ex.1009 - 664 patent

May 5, 2021EXHIBITPETITIONER

Ex.1010 - 758 patent

May 5, 2021EXHIBITPETITIONER

Ex.1011 - Semeraro

May 5, 2021EXHIBITPETITIONER

Ex.1012 - Regeneron (28-April-2008)

May 5, 2021EXHIBITPETITIONER

Ex.1013 - Regeneron (8-May-2008)

May 5, 2021EXHIBITPETITIONER

Ex.1014 - NCT-795

May 5, 2021EXHIBITPETITIONER

Ex.1015 - NCT-377

May 5, 2021EXHIBITPETITIONER

Ex.1016 - Monthly-Dosing-Patents

May 5, 2021EXHIBITPETITIONER

Ex.1017 - 338 FH

May 5, 2021EXHIBITPETITIONER

Ex.1018 - Heier-2012

May 5, 2021EXHIBITPETITIONER

Ex.1019 - 069 patent

May 5, 2021EXHIBITPETITIONER

Ex.1020 - Heier-2009

May 5, 2021EXHIBITPETITIONER

Ex.1021 - 2009 10-Q

May 5, 2021EXHIBITPETITIONER

Ex.1022 - 757 patent

May 5, 2021EXHIBITPETITIONER

Ex.1023 - 959 patent

May 5, 2021EXHIBITPETITIONER

Ex.1024 - 758 FH - 12-22-2011 PTE

May 5, 2021EXHIBITPETITIONER

Ex.1025 - Engelbert-2010

May 5, 2021EXHIBITPETITIONER

Ex.1026 - Engelbert-2009

May 5, 2021EXHIBITPETITIONER

Ex.1027 - Spaide

May 5, 2021EXHIBITPETITIONER

Ex.1028 - Regeneron (30-April-2009)

May 5, 2021EXHIBITPETITIONER

Ex.1029 - NCT-973

May 5, 2021EXHIBITPETITIONER

Ex.1030 - Mitchell

May 5, 2021EXHIBITPETITIONER

Ex.1031 - Massin

May 5, 2021EXHIBITPETITIONER

Ex.1032 - Bayer (8-May-2008)

May 5, 2021EXHIBITPETITIONER

Ex.1033 - Dix

May 5, 2021EXHIBITPETITIONER

Ex.1034 - Fung

May 5, 2021EXHIBITPETITIONER

Ex.1035 - Lalwani

May 5, 2021EXHIBITPETITIONER

Ex.1036 - Campochiaro

May 5, 2021EXHIBITPETITIONER

Ex.1037 - Steinbrook

May 5, 2021EXHIBITPETITIONER

Ex.1038 - Albini CV

May 5, 2021EXHIBITPETITIONER

Ex.1039 - 095 patent

May 5, 2021EXHIBITPETITIONER

Ex.1040 - WHO Drug Info

May 5, 2021EXHIBITPETITIONER

Ex.1041 - Regeneron (26-February-2009)

May 5, 2021EXHIBITPETITIONER

Ex.1042 - NIH AMD

May 5, 2021EXHIBITPETITIONER

Ex.1043 - Brown

May 5, 2021EXHIBITPETITIONER

Ex.1044 - NIH DR

May 5, 2021EXHIBITPETITIONER

Ex.1045 - Ferrara-1999

May 5, 2021EXHIBITPETITIONER

Ex.1046 - Ferrara-2005

May 5, 2021EXHIBITPETITIONER

Ex.1047 - Bashshur

May 5, 2021EXHIBITPETITIONER

Ex.1048 - Lucentis

May 5, 2021EXHIBITPETITIONER

Ex.1049 - Spielberg

May 5, 2021EXHIBITPETITIONER

Ex.1050 - Schmidt-Erfuth

May 5, 2021EXHIBITPETITIONER

Ex.1051 - Keane

May 5, 2021EXHIBITPETITIONER

Ex.1052 - Rudge

May 5, 2021EXHIBITPETITIONER

Ex.1053 - Regeneron (27-March-2007)

May 5, 2021EXHIBITPETITIONER

Ex.1054 - Regeneron (2-August-2007)

May 5, 2021EXHIBITPETITIONER

Ex.1055 - Retina Society Meeting Presentation

May 5, 2021EXHIBITPETITIONER

Ex.1056 - Regeneron (28-September-2008)

May 5, 2021EXHIBITPETITIONER

Ex.1057 - Regeneron (18-February-2010)

May 5, 2021EXHIBITPETITIONER

Ex.1058 - ARVONews Winter-Spring 2008

May 5, 2021EXHIBITPETITIONER

Ex.1059 - ARVONews Summer 2007

May 5, 2021EXHIBITPETITIONER

Ex.1060 - Korobelnik

May 5, 2021EXHIBITPETITIONER

Ex.1061 - Gerritsen CV

May 5, 2021EXHIBITPETITIONER

Ex.1062 - EP-325

May 5, 2021EXHIBITPETITIONER

Ex.1063 - EP-325-FH

May 5, 2021EXHIBITPETITIONER

Ex.1064 - Wayback-BJO-Online First

May 5, 2021EXHIBITPETITIONER

Ex.1065 - BJO-Article Metrics

May 5, 2021EXHIBITPETITIONER

Ex.1066 - Bayer (18-February-2010)

May 5, 2021EXHIBITPETITIONER

Ex.1067 - Bayer (28-April-2008)

May 5, 2021EXHIBITPETITIONER

Ex.1068 - Regeneron (14-September-2009)

May 5, 2021EXHIBITPETITIONER

Ex.1069 - Background-ClinicalTrials.gov

May 5, 2021EXHIBITPETITIONER

Ex.1070 - Wayback-Affidavit (069)

May 5, 2021EXHIBITPETITIONER

Ex.1071 - Holz

May 5, 2021EXHIBITPETITIONER

Ex.1072 - Reichert

May 5, 2021EXHIBITPETITIONER

Ex.1073 - Anderson

May 5, 2021EXHIBITPETITIONER

Ex.1074 - Ciulla

May 5, 2021EXHIBITPETITIONER

Ex.1075 - Ni

May 5, 2021EXHIBITPETITIONER

Ex.1076 - Zarbin

May 5, 2021EXHIBITPETITIONER

Ex.1077 - Corporate Finance Institute

May 5, 2021EXHIBITPETITIONER

Ex.1078 - Schneider

May 5, 2021EXHIBITPETITIONER

Ex.1079 - Kuepper

May 5, 2021EXHIBITPETITIONER

Ex.1080 - Zucchi

May 5, 2021EXHIBITPETITIONER

Ex.1081 - Hayes

May 5, 2021EXHIBITPETITIONER

Ex.1082 - 069 amino acid sequences

May 5, 2021EXHIBITPETITIONER

Ex.1083 - 069 nucleotide sequences

May 5, 2021EXHIBITPETITIONER

Ex.1084 - Weigand

May 5, 2021EXHIBITPETITIONER

Ex.1085 - Shams

May 5, 2021EXHIBITPETITIONER

Ex.1086 - History-ClinicalTrials.gov

May 5, 2021EXHIBITPETITIONER

Ex.1087 - Wayback Affidavit (338)

May 5, 2021EXHIBITPETITIONER

Ex.1088 - Nguyen-2006

May 5, 2021EXHIBITPETITIONER

Ex.1089 - Regeneron (19-August-2008)

May 5, 2021EXHIBITPETITIONER

Ex.1090 - Kim

May 5, 2021EXHIBITPETITIONER

Ex.1091 - Eylea PI

May 5, 2021EXHIBITPETITIONER

Ex.1092 - Bayer (19-August-2008)

May 5, 2021EXHIBITPETITIONER

Ex.1093 - 338 amino acid sequences

May 5, 2021EXHIBITPETITIONER

Ex.1094 - 338 nucleotide sequences

May 5, 2021EXHIBITPETITIONER

Petition

May 5, 2021PAPERPETITIONER

Power of Attorney

May 5, 2021PAPERPETITIONER