The detailed information for PTAB case with proceeding number IPR2021-00902 filed by Laboratory Corporation of America Holdings against Ravgen, Inc. on May 3, 2021. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Case Details

Proceeding Number
IPR2021-00902
Filing Date
May 3, 2021
Petitioner
Laboratory Corporation of America Holdings
Respondent
Ravgen, Inc.
Status
Final Written Decision
Respondent Application Number
10661165
Respondent Tech Center
1600
Respondent Patent Number
7332277
Institution Decision Date
Nov 5, 2021
Termination Date
Nov 1, 2022

Proceeding Documents

The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.


Document NameFiling DateCategoryFiling Party

Alert me when new update on this case

Other: Fed Circuit mandate

Jul 2, 2025PAPERBOARD

Other: other court decision

Jul 2, 2025PAPERBOARD

Petitioner Notice of Appeal

Dec 30, 2022PAPERPETITIONER

Final Written Decision: JUDGMENT Final Written Decision Determining No Challenged Claims Unpatentable 35 U.S.C. § 318(a) Granting Patent Owner’s Motion for Entry of Protective Order and to Seal; Granting Petitioner’s Motion to Seal 37 C.F.R. §§ 42.14, 42.54 Dismissing Petitioner’s Motion to Exclude 37 C.F.R. § 42.64(c) 

Nov 1, 2022PAPERBOARD

Other: Hearing transcript

Sep 7, 2022PAPERBOARD

Patent Owner's Updated Exhibit List

Aug 25, 2022PAPERPATENT OWNER

Ex. 2305

Aug 25, 2022EXHIBITPATENT OWNER

Petitioner's Post-Hearing Brief

Aug 15, 2022PAPERPETITIONER

Patent Owner's Post-Hearing Brief

Aug 15, 2022PAPERPATENT OWNER

Exhibit 3005

Aug 10, 2022EXHIBITBOARD

Exhibit 3006

Aug 10, 2022EXHIBITBOARD

Ex 3004

Aug 5, 2022EXHIBITBOARD

Petitioner's Updated Exhibit List

Jul 27, 2022PAPERPETITIONER

[CORRECTED] Petitioner's Demonstratives

Jul 27, 2022EXHIBITPETITIONER

Patent Owner's Updated Exhibit List

Jul 26, 2022PAPERPATENT OWNER

Ex. 2304

Jul 26, 2022EXHIBITPATENT OWNER

Petitioner's Reply to Patent Owner's Opposition to Motion to Exclude Evidence

Jul 25, 2022PAPERPETITIONER

Patent Owner's Opposition to Petitioner's Motion to Exclude Evidence

Jul 20, 2022PAPERPATENT OWNER

Petitioner's Demonstratives

Jul 20, 2022EXHIBITPETITIONER

Notice of Stipulation to Modify Date for Serving Oral Hearing Demonstratives

Jul 18, 2022PAPERPATENT OWNER

Petitioner's Motion to Exclude Evidence

Jul 14, 2022PAPERPETITIONER

Setting Oral Argument 37 C.F.R. § 42.70

Jun 24, 2022PAPERBOARD

Patent Owner's Request For Oral Argument

Jun 23, 2022PAPERPATENT OWNER

Petitioner Request For Oral Argument

Jun 22, 2022PAPERPETITIONER

Petitioner's Objections to Evidence Submitted With Patent Owner's Sur-Reply

Jun 16, 2022PAPERPETITIONER

Patent Owner's Sur-Reply

Jun 10, 2022PAPERPATENT OWNER

Ex. 2298

Jun 10, 2022EXHIBITPATENT OWNER

Ex. 2299

Jun 10, 2022EXHIBITPATENT OWNER

Ex. 2300

Jun 10, 2022EXHIBITPATENT OWNER

Ex. 2301

Jun 10, 2022EXHIBITPATENT OWNER

Patent Owner's Updated Mandatory Notices

May 12, 2022PAPERPATENT OWNER

Patent Owner's Notice of Deposition of Jeremy S. Edwards, Ph.D.

May 11, 2022PAPERPATENT OWNER

Notice of Stipulation to Modify Due Date 3

May 11, 2022PAPERPATENT OWNER

Petitioner's Updated Mandatory Notice Pursuant to 37 C.F.R. Section 42.8

May 5, 2022PAPERPETITIONER

Petitioner's Updated Power of Attorney

May 5, 2022PAPERPETITIONER

Patent Owner's Objections to Evidence Filed with Petitioner's Reply

Apr 28, 2022PAPERPATENT OWNER

Granting Patent Owner Motions for Admission Pro Hac Vice of Joze Welsh 37 C.F.R. § 42.10

Apr 22, 2022PAPERBOARD

Petitioner Reply to Patent Owner Response (Filed Under Seal)

Apr 21, 2022PAPERPETITIONER

Petitioner Unopposed Motion to Seal Under Stipulated Protective Order

Apr 21, 2022PAPERPETITIONER

Petitioner Reply to Patent Owner Response (Filed as Redacted)

Apr 21, 2022PAPERPETITIONER

Deposition Transcript of Brian Van Ness

Apr 21, 2022EXHIBITPETITIONER

de Paula et al., The use of fixative solutions through the ages: a comprehensive review, Acta Sci Anat. 1:21-28 (2018)

Apr 21, 2022EXHIBITPETITIONER

Supplemental Declaration of Jeremy S. Edwards

Apr 21, 2022EXHIBITPETITIONER

U.S. Provisional Application No. 60/314,151 to Rao

Apr 21, 2022EXHIBITPETITIONER

U.S. Patent No. 5,849,517 to Ryan

Apr 21, 2022EXHIBITPETITIONER

U.S. Patent No. 10,966,421 to Ryan

Apr 21, 2022EXHIBITPETITIONER

Srinivasan et al. Effects of Tissue Fixation on Nucleic Acids, Am. J. Pathology 161(6):1961-71 (2002)

Apr 21, 2022EXHIBITPETITIONER

Das et al., Effects of a novel cell stabilizing reagent on DNA amplification by PCR as compared to traditional stabilizing reagents, Acta Histochemica 116:55-60 (2014)

Apr 21, 2022EXHIBITPETITIONER

Jacob et al., Does Formaldehyde Increase Cell Free DNA in Maternal Plasma Specimens?, Lab���y Med. 47(4):286-92 (2016)

Apr 21, 2022EXHIBITPETITIONER

Deposition Transcript of Paul Meyer (Under Seal)

Apr 21, 2022EXHIBITPETITIONER

Deposition Transcript of Paul Meyer (Redacted)

Apr 21, 2022EXHIBITPETITIONER

Caruso, Evolution of non-invasive prenatal testing (NIPT) testing, SeraCare.com (Feb. 5, 2020), https://blog.seracare.com/ngs/evolution-of-non-invasive-prenatal-testing-nipt-testing

Apr 21, 2022EXHIBITPETITIONER

Fan et al., Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood, PNAS 105(42) 16266-71 (2008)

Apr 21, 2022EXHIBITPETITIONER

Yuzuki, What is Non-Invasive Prenatal Testing (NIPT), SeraCare.com (2015), https://blog.seracare.com/ngs/home/tabid/294/artmid/989/articleid/23/what-is-non-invasive-prenatal-testing-nipt.aspx

Apr 21, 2022EXHIBITPETITIONER

Chiu et al., Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma, PNAS 105(51):20458-63 (2008)

Apr 21, 2022EXHIBITPETITIONER

Chinnapapagari et al., Treatment of maternal blood samples with formaldehyde does not alter the proportion of circulatory

Apr 21, 2022EXHIBITPETITIONER

Chung et al., Lack of dramatic enrichment of fetal DNA in maternal plasma by formaldehyde treatment, Clin. Chem. 51:655-58 (2005)

Apr 21, 2022EXHIBITPETITIONER

Patent Owner's Motion for Admission Pro Hac Vice of Joze Welsh

Apr 13, 2022PAPERPATENT OWNER

Ex. 2284

Apr 13, 2022EXHIBITPATENT OWNER

Patent Owner's Updated Mandatory Notices

Apr 4, 2022PAPERPATENT OWNER

Petitioner's Notice of Deposition of Paul K. Meyer

Mar 24, 2022PAPERPETITIONER

Petitioner's Notice of Deposition of Dr. Brian Van Ness

Mar 18, 2022PAPERPETITIONER

Petitioner's Objections to Evidence Submitted with Patent Owner's Response

Feb 3, 2022PAPERPETITIONER

Order Granting Motion to Stay Reexamination

Feb 1, 2022PAPERBOARD

Ex. 2080 - FILED UNDER SEAL

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2170 - FILED UNDER SEAL

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2171 - FILED UNDER SEAL

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2172 - FILED UNDER SEAL

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2173 - FILED UNDER SEAL

Jan 27, 2022EXHIBITPATENT OWNER

Patent Owner's Response - FILED UNDER SEAL

Jan 27, 2022PAPERPATENT OWNER

Patent Owner's Unopposed Motion for Entry of Stipulated Protective Order and to Seal Patent Owner's Response and Exhibits 2080, 2170-2173

Jan 27, 2022PAPERPATENT OWNER

Ex. 2007

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2009

Jan 27, 2022EXHIBITPATENT OWNER

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Jan 27, 2022EXHIBITPATENT OWNER

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Ex. 2078

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Ex. 2079

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Ex. 2080 - REDACTED

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Ex. 2081

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Ex. 2082

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Ex. 2083

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Ex. 2210

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Ex. 2214

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Ex. 2215

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2216

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2218

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2219

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2220

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2221

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2222

Jan 27, 2022EXHIBITPATENT OWNER

Ex. 2230

Jan 27, 2022EXHIBITPATENT OWNER

Patent Owner's Response [REDACTED]

Jan 27, 2022PAPERPATENT OWNER

Ex. 3003

Jan 26, 2022EXHIBITBOARD

ORDER Granting Patent Owners Motions for Admission Pro Hac Vice of Kerri-Ann Limbeek 37 C.F.R. sec 42.10

Jan 25, 2022PAPERBOARD

Ex. 2224

Jan 21, 2022EXHIBITPATENT OWNER

Ex. 2225

Jan 21, 2022EXHIBITPATENT OWNER

Ex. 2228

Jan 21, 2022EXHIBITPATENT OWNER

Ex. 2229

Jan 21, 2022EXHIBITPATENT OWNER

Patent Owner's Motion to Stay Ex Parte Reexamination

Jan 21, 2022PAPERPATENT OWNER

Patent Owner's Notice of Deposition of Jeremy S. Edwards, PhD

Jan 5, 2022PAPERPATENT OWNER

Patent Owner's Motion for Admission Pro Hac Vice of Kerri-Ann Limbeek

Jan 3, 2022PAPERPATENT OWNER

Ex. 2056

Jan 3, 2022EXHIBITPATENT OWNER

Exhibit 3002

Jan 3, 2022EXHIBITBOARD

Patent Owner's Updated Mandatory Notices

Dec 22, 2021PAPERPATENT OWNER

Patent Owner���s Objections to Evidence Filed with the Petition

Nov 22, 2021PAPERPATENT OWNER

Order: Scheduling Order

Nov 8, 2021PAPERBOARD

Institution Decision: Grant

Nov 5, 2021PAPERBOARD

Updated Mandatory Notices for Patent Owner, Ravgen, Inc.

Oct 14, 2021PAPERPATENT OWNER

Patent Owner's Authorized Sur-Reply

Sep 17, 2021PAPERPATENT OWNER

Petitioner's Authorized Reply to Patent Owner's Preliminary Response

Sep 10, 2021PAPERPETITIONER

EXPUNGED

Sep 3, 2021EXHIBITBOARD

E-mail

Sep 3, 2021EXHIBITBOARD

Exhibit 2001 - Declaration

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2002

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2003

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2004

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2005

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2011

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2012

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2013

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2031

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2032

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2033

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2034

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2035

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2039

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2041 - Vol 1 of 7

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2041 - Vol 2 of 7

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2041 - Vol 3 of 7

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2041 - Vol 4 of 7

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Exhibit 2041 - Vol 5 of 7

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Exhibit 2041 - Vol 6 of 7

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Exhibit 2041 - Vol 7 of 7

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2049

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2050

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2051

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2052

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2053

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2054

Aug 13, 2021EXHIBITPATENT OWNER

Exhibit 2055

Aug 13, 2021EXHIBITPATENT OWNER

Patent Owner's Preliminary Response

Aug 13, 2021PAPERPATENT OWNER

Ravgen, Inc.'s Updated Mandatory Notices

Aug 4, 2021PAPERPATENT OWNER

Ravgen, Inc.'s Mandatory Notices

May 18, 2021PAPERPATENT OWNER

Ravgen, Inc.'s Power of Attorney

May 18, 2021PAPERPATENT OWNER

Petitioner Laboratory Corporation of America Holdings Notice of Filing Corrected Exhibit 1016

May 17, 2021PAPERPETITIONER

Corrected Exhibit 1016 - Banfi et al., Use of Anticoagulants in Diagnostic Laboratory Investigations, World Health Organization [WHO] (2002)

May 17, 2021EXHIBITPETITIONER

Notice of Accepting Corrected Petition

May 17, 2021PAPERBOARD

Notice of Accord Filing Date

May 14, 2021PAPERBOARD

Petition For Inter Partes Review

May 3, 2021PAPERPETITIONER

U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

Declaration of Jeremy S. Edwards, Ph.D.

May 3, 2021EXHIBITPETITIONER

Chiu et al., Effects of Blood Processing Protocols on Fetal and Total DNA Quantification in Maternal Plasma, Clinical Chem. 47(9)-1607-13 (2001)

May 3, 2021EXHIBITPETITIONER

U.S. Patent. No. 5,648,220 to Bianchi & DeMaria

May 3, 2021EXHIBITPETITIONER

PCT Publication No. WO 03/018757 to Rao et al.

May 3, 2021EXHIBITPETITIONER

PCT Publication No. WO 95/01796 to Granger et al.

May 3, 2021EXHIBITPETITIONER

PCT Application No. PCT/US03/06198 to Dhallan

May 3, 2021EXHIBITPETITIONER

U.S. Patent No. 6,977,162 to Dhallan

May 3, 2021EXHIBITPETITIONER

PCT Application No. PCT/US03/27308 to Dhallan

May 3, 2021EXHIBITPETITIONER

U.S. Patent No. 7,208,274 to Dhallan

May 3, 2021EXHIBITPETITIONER

U.S. Provisional Application No. 60/378,354 to Dhallan

May 3, 2021EXHIBITPETITIONER

U.S. Provisional Application No. 60/360,232 to Dhallan

May 3, 2021EXHIBITPETITIONER

Lambert et al., Male Microchimerism in Healthy Women and Women with Scleroderma: Cells or Circulating DNA, A Quantitative Answer, Blood 100(8)-2845-51 (2002)

May 3, 2021EXHIBITPETITIONER

Lee et al., Quantitation of Genomic DNA in Plasma and Serum Samples: Higher Concentrations of Genomic DNA Found in Serum than in Plasma, Transfusion 41:276-82 (2001)

May 3, 2021EXHIBITPETITIONER

Lo et al., Two-Way Cell Traffic Between Mother and Fetus: Biologic and Clinical Implications, Blood 88(11):4390-95 (1996)

May 3, 2021EXHIBITPETITIONER

Banfi et al., Use of Anticoagulants in Diagnostic Laboratory Investigations, World Health Organization (WHO) (2002)

May 3, 2021EXHIBITPETITIONER

PCT Publication No. WO 95/003431

May 3, 2021EXHIBITPETITIONER

Miller & Lai, Human and Mouse Hematopoietic Colony-Forming Cell Assays, Chapter 6, in Methods in Molecular Biology: Basic Cell Culture Protocols 290:71 (Helgason & Miller eds., Humana Press 3d ed. 2002)

May 3, 2021EXHIBITPETITIONER

European Patent No. 1439897

May 3, 2021EXHIBITPETITIONER

European Patent No. 1439897

May 3, 2021EXHIBITPETITIONER

European Patent No. 1439897

May 3, 2021EXHIBITPETITIONER

European Patent No. 1439897

May 3, 2021EXHIBITPETITIONER

Lo et al., Presence of Fetal DNA in Maternal Plasma and Serum, Lancet 350:485-87 (1997)

May 3, 2021EXHIBITPETITIONER

Lo et al., Quantitative Analysis of Fetal DNA in Maternal Plasma and Serum: Implications for Noninvasive Prenatal Diagnosis, Am. J. Hum. Gen. 62:768-75 (1998)

May 3, 2021EXHIBITPETITIONER

Pertl & Bianchi, Fetal DNA in Maternal Plasma: Emerging Clinical Applications, Obstetrics and Gynecology 98: 483-490 (2001)

May 3, 2021EXHIBITPETITIONER

Hahn et al., Quantification of Circulating DNA: in the Preparation Lies the Rub, Clin. Chem. 47(9):1577-78 (2001)

May 3, 2021EXHIBITPETITIONER

Declaration and Affirmation of Brenda Ray on Authentication of Publication of Chiu

May 3, 2021EXHIBITPETITIONER

File History for U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

File History for U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

File History for U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

File History for U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

File History for U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

File History for U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

File History for U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

File History for U.S. Patent. No. 7,332,277 to Dhallan

May 3, 2021EXHIBITPETITIONER

Heraeus Megafuge Operating Instructions

May 3, 2021EXHIBITPETITIONER

Paraformaldehyde, Formaldehyde and Formalin, Duke Univ., https://microscopy.duke.edu/guides/paraformaldehydeformaldehyde-formalin (last visited Apr. 8, 2021)

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May 3, 2021EXHIBITPETITIONER

Tan & Yiap, DNA, RNA, and Protein Extraction: The Past and The Present, Hindawi, (Nov. 30, 2009) https://www.hindawi.com/journals/bmri/2009/574398/

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Qiagen, QIAamp DNA Mini Kit and QIAamp DNA Blood Mini Kit Handbook (2003), http://depts.washington.edu/kellylab/wordpress/wpcontent/uploads/2019/03/QIAGEN_protocol.pdf

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May 3, 2021EXHIBITPETITIONER

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May 3, 2021EXHIBITPETITIONER

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May 3, 2021EXHIBITPETITIONER

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May 3, 2021EXHIBITPETITIONER

Power of Attorney

May 3, 2021PAPERPETITIONER