The detailed information for PTAB case with proceeding number IPR2022-01440 filed by Bausch & Lomb Incorporated et al. against ZeaVision, LLC on Aug 19, 2022. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Case Details

Proceeding Number
IPR2022-01440
Filing Date
Aug 19, 2022
Petitioner
Bausch & Lomb Incorporated et al.
Respondent
ZeaVision, LLC
Status
Terminated-Settled
Respondent Application Number
17304708
Respondent Tech Center
1600
Respondent Patent Number
11173133
Institution Decision Date
Feb 10, 2023
Termination Date
Aug 21, 2023

Proceeding Documents

The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.


Document NameFiling DateCategoryFiling Party

Alert me when new update on this case

Termination Decision: TERMINATION Due to Settlement After Institution of Trial 35 U.S.C. § 317, 37 C.F.R. § 42.74

Aug 21, 2023PAPERBOARD

Exhibit 3001

Aug 16, 2023EXHIBITBOARD

Joint Motion To Terminate Proceedings

Aug 16, 2023PAPERPETITIONER

Joint Request To Treat Settlement Agreement As Business Confidential Information And To Keep Separate

Aug 16, 2023PAPERPETITIONER

Confidential Settlement Agreement Filed Under Seal

Aug 16, 2023EXHIBITPETITIONER

Order

Aug 3, 2023PAPERBOARD

PHV Motion

Jul 21, 2023PAPERPATENT OWNER

DECLARATION OF JEREMIAH W. NIXON IN SUPPORT OF MOTION FOR ADMISSION PRO HAC VICE

Jul 21, 2023EXHIBITPATENT OWNER

PATENT OWNER’S UPDATED MANDATORY NOTICE

Jul 21, 2023PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

Jul 21, 2023PAPERPATENT OWNER

Petitioner's Notice of Deposition Of Dr. C. Kathleen Dorey

Jul 17, 2023PAPERPETITIONER

Joint Notice Of Stipulation To Change Due Dates

Jul 14, 2023PAPERPETITIONER

ORDER Granting Petitioner’s Motions for Admission Pro Hac Vice of Steven C. Kline and Monica Chou 37 C.F.R. sec 42.10

Jul 12, 2023PAPERBOARD

PHV Motion for S Kline

Jun 26, 2023PAPERPETITIONER

PHV Motion for M Chou

Jun 26, 2023PAPERPETITIONER

Declaration of S Kline

Jun 23, 2023EXHIBITPETITIONER

Declaration of M Chou

Jun 23, 2023EXHIBITPETITIONER

Petitioner's Updated Mandatory Notice

Jun 23, 2023PAPERPETITIONER

Petitioner's Updated Exhibit List

Jun 23, 2023PAPERPETITIONER

Order: Panel Change Order

May 8, 2023PAPERBOARD

PATENT OWNER’S RESPONSE TO PETITION PURSUANT TO 37 C.F.R. § 42

May 5, 2023PAPERPATENT OWNER

Effect of Zeaxanthin and Antioxidant Supplementation on Vascular Endothelial Growth Factor (VEGF) Expression in Apolipoprotein-E Deficient Mice, Fernández-Robredo et al

May 5, 2023EXHIBITPATENT OWNER

Supplemental Declaration of Dr. C. Kathleen Dorey, Ph. D.

May 5, 2023EXHIBITPATENT OWNER

Appeal 2013-000129 for Application 10/746,403

May 5, 2023EXHIBITPATENT OWNER

Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart S, Hammar S. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996

May 5, 2023EXHIBITPATENT OWNER

Bone RA, Landrum JT, Friedes LM, Gomez CM, Kilburn MD, Menendez E, Vidal I, Wang W (1997) Distribution of lutein and zeaxanthin stereoisomers in the human retina. Exp Eye Res 64, 211-218

May 5, 2023EXHIBITPATENT OWNER

Bone RA, Landrum JT, Hime GW, Cains A, Zamor J (1993) Stereochemistry of the human macular carotenoids. Invest Ophthalmol Vis Sci 34, 2033-2040

May 5, 2023EXHIBITPATENT OWNER

Shyam R, Gorusupudi A, Nelson K, Horvath MP, Bernstein PS (2017) RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye. Proc Natl Acad Sci U S A 114, 10882-10887

May 5, 2023EXHIBITPATENT OWNER

Arunkumar R, Gorusupudi A, Bernstein PS (2020) The macular carotenoids: A biochemical overview. Biochim Biophys Acta Mol Cell Biol Lipids 1865, 158617

May 5, 2023EXHIBITPATENT OWNER

Mares J (2016) Lutein and Zeaxanthin Isomers in Eye Health and Disease. Annu Rev Nutr 36, 571-602

May 5, 2023EXHIBITPATENT OWNER

Nolan JM, Beatty S, Meagher KA, Howard AN, Kelly D, Thurnham DI (2014) Verification of Meso-Zeaxanthin in Fish. J Food Process Technol 5, 335

May 5, 2023EXHIBITPATENT OWNER

Nolan JM, Beatty S, Meagher KA, Howard AN, Kelly D, Thurnham DI (2014) Verification of Meso-Zeaxanthin in Fish. J Food Process Technol 5, 335

May 5, 2023EXHIBITPATENT OWNER

Everts S (2013) Mirror molecules. Sci Am 308, 78-81.

May 5, 2023EXHIBITPATENT OWNER

Avetisov V, Goldanskii V (1996) Mirror symmetry breaking at the molecular level. Proc Natl Acad Sci U S A 93, 11435-11442

May 5, 2023EXHIBITPATENT OWNER

Institute of Medicine (US) Panel on Dietary Antioxidants and Related Compounds (2000) Vitamin E In Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academies Press (US);, Washington DC.

May 5, 2023EXHIBITPATENT OWNER

Office of Dietary Supplements, Vitamin E. Fact sheet for health professionals, National Institutes of Health, https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/, March 26, 2021, Accessed 1/22/2023.

May 5, 2023EXHIBITPATENT OWNER

Jiang Q, Christen S, Shigenaga MK, Ames BN (2001) gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74, 714-722.

May 5, 2023EXHIBITPATENT OWNER

Di Mambro VM, Azzolini AE, Valim YM, Fonseca MJ (2003) Comparison of antioxidant activities of tocopherols alone and in pharmaceutical formulations. Int J Pharm 262, 93-99

May 5, 2023EXHIBITPATENT OWNER

Forman HJ, Zhang H (2021) Targeting oxidative stress in disease: promise and limitations of antioxidant therapy. Nat Rev Drug Discov 20, 689-709

May 5, 2023EXHIBITPATENT OWNER

Sharifi-Rad M, Anil Kumar NV, Zucca P, Varoni EM, Dini L, Panzarini E, Rajkovic J, et al. (2020) Lifestyle, oxidative stress, and antioxidants: Back and forth in the pathophysiology of chronic diseases Front Physiol 11, 694

May 5, 2023EXHIBITPATENT OWNER

Crabtree DV, Adler AJ, Snodderly DM (1996) Radial distribution of tocopherols in rhesus monkey retina and retinal pigment epithelium-choroid. Invest Ophthalmol Vis Sci 37, 61-76

May 5, 2023EXHIBITPATENT OWNER

Yeum KJ, Taylor A, Tang G, Russell RM (1995) Measurement of carotenoids, retinoids, and tocopherols in human lenses. Invest Ophthalmol Vis Sci 36, 2756-2761

May 5, 2023EXHIBITPATENT OWNER

Bieri JG, Evarts RP (1974) Gamma tocopherol: metabolism, biological activity and significance in human vitamin E nutrition. Am J Clin Nutr 27, 980-986

May 5, 2023EXHIBITPATENT OWNER

Giovannucci E (2000) Gamma-tocopherol: a new player in prostate cancer prevention? J Natl Cancer Inst 92, 1966-1967

May 5, 2023EXHIBITPATENT OWNER

Helzlsouer KJ, Huang HY, Alberg AJ, Hoffman S, Burke A, Norkus EP, Morris JS, Comstock GW (2000) Association between alpha-tocopherol, gamma-tocopherol, selenium, and subsequent prostate cancer. J Natl Cancer Inst 92, 2018-2023

May 5, 2023EXHIBITPATENT OWNER

Age-Related Eye Disease Study Research G (2001) A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol 119, 1439-1452

May 5, 2023EXHIBITPATENT OWNER

Rozanowska M, Edge R, Land EJ, Navaratnam S, Sarna T, Truscott TG (2019) Scavenging of retinoid cation radicals by urate, Trolox, and alpha-, beta-, gamma-, and delta-tocopherols. Int J Mol Sci 20

May 5, 2023EXHIBITPATENT OWNER

Reme CE, Malnoe A, Jung HH, Wei Q, Munz K (1994) Effect of dietary fish oil on acute light- induced photoreceptor damage in the rat retina. Invest Ophthalmol Vis Sci 35, 78-90

May 5, 2023EXHIBITPATENT OWNER

Thomson LR, Toyoda Y, Delori FC, Garnett KM, Wong ZY, Nichols CR, Cheng KM, Craft NE, Dorey CK (2002) Long term dietary supplementation with zeaxanthin reduces photoreceptor death in light-damaged Japanese quail. Exp Eye Res 75, 529-542

May 5, 2023EXHIBITPATENT OWNER

Trevithick-Sutton CC, Foote CS, Collins M, Trevithick JR (2006) The retinal carotenoids zeaxanthin and lutein scavenge superoxide and hydroxyl radicals: a chemiluminescence and ESR study. Mol Vis 12, 1127-1135.

May 5, 2023EXHIBITPATENT OWNER

Aonuma H, Koide K, Masuda K, Watanabe I (1997) Retinal light damage: protective effect of alpha-tocopherol. Jpn J Ophthalmol 41, 160-167

May 5, 2023EXHIBITPATENT OWNER

Christen S, Woodall AA, Shigenaga MK, Southwell-Keely PT, Duncan MW, Ames BN (1997) gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha- tocopherol: physiological implications. Proc Natl Acad Sci U S A 94, 3217-3222

May 5, 2023EXHIBITPATENT OWNER

Liu M, Wallin R, Wallmon A, Saldeen T (2002) Mixed tocopherols have a stronger inhibitory effect on lipid peroxidation than alpha-tocopherol alone. J Cardiovasc Pharmacol 39, 714-721

May 5, 2023EXHIBITPATENT OWNER

Huang HY, Appel LJ (2003) Supplementation of diets with alpha-tocopherol reduces serum concentrations of gamma- and delta-tocopherol in humans. J Nutr 133, 3137-3140

May 5, 2023EXHIBITPATENT OWNER

Handelman GJ, Machlin LJ, Fitch K, Weiter JJ, Dratz EA (1985) Oral alpha-tocopherol supplements decrease plasma gamma-tocopherol levels in humans. J Nutr 115, 807-813

May 5, 2023EXHIBITPATENT OWNER

Morton LW, Ward NC, Croft KD, Puddey IB (2002) Evidence for the nitration of gamma- tocopherol in vivo: 5-nitro-gamma-tocopherol is elevated in the plasma of subjects with coronary heart disease. Biochem J 364, 625-628

May 5, 2023EXHIBITPATENT OWNER

Order: SCHEDULING ORDER

Feb 14, 2023PAPERBOARD

Institution Decision: Grant

Feb 10, 2023PAPERBOARD

EXPUNGED

Feb 10, 2023PAPERBOARD

Patent Owner's Preliminary Response

Nov 18, 2022PAPERPATENT OWNER

Declaration of Dr. C. Kathleen Dorey, Ph.D.

Nov 18, 2022EXHIBITPATENT OWNER

Handelman GJ (2001) The evolving role of carotenoids in human biochemistry

Nov 18, 2022EXHIBITPATENT OWNER

Sies H, Stahl W, Sundquist AR (1992) Antioxidant functions of vitamins. Vitamins E and C, beta-carotene, and other carotenoids

Nov 18, 2022EXHIBITPATENT OWNER

Tang G (2010) Bioconversion of dietary provitamin A carotenoids to vitamin A in humans.

Nov 18, 2022EXHIBITPATENT OWNER

Ala-Laurila P, Kolesnikov AV, Crouch RK, Tsina E, Shukolyukov SA, Govardovskii VI, Koutalos Y, Wiggert B, Estevez ME, Cornwall MC (2006) Visual cycle: Dependence of retinol production and removal on photoproduct decay and cell morphology

Nov 18, 2022EXHIBITPATENT OWNER

Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart S, Hammar S (1996) Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease

Nov 18, 2022EXHIBITPATENT OWNER

Leo, M.A. & Lieber, C.S. (1999) Alcohol, vitamin A, and beta-carotene: Adverse interactions, including hepatotoxicity and carcinogenicity

Nov 18, 2022EXHIBITPATENT OWNER

Albanes D, Virtamo J, Taylor PR, Rautalahti M, Pietinen P, Heinonen OP (1997) Effects of supplemental beta-carotene, cigarette smoking, and alcohol consumption on serum carotenoids in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study

Nov 18, 2022EXHIBITPATENT OWNER

The Alpha-Tocopherol BCCPSG (1994) The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

Nov 18, 2022EXHIBITPATENT OWNER

Speizer FE, Colditz GA, Hunter DJ, Rosner B, Hennekens C (1999) Prospective study of smoking, antioxidant intake, and lung cancer in middle-aged women (USA)

Nov 18, 2022EXHIBITPATENT OWNER

Goodman GE, Schaffer S, Omenn GS, Chen C, King I (2003) The association between lung and prostate cancer risk, and serum micronutrients: results and lessons learned from beta-carotene and retinol efficacy trial.

Nov 18, 2022EXHIBITPATENT OWNER

Mannisto S, Smith-Warner SA, Spiegelman D, Albanes D, Anderson K, van den Brandt PA, Cerhan JR, Colditz G, Feskanich D, Freudenheim JL, Giovannucci E, Goldbonhm RA, Graham S, Miller AB, Rohan TE, Virtamo J, Willett WC, Hunter DJ (2004) Dietary carotenoids and risk of lung cancer in a pooled analysis of seven cohort studies

Nov 18, 2022EXHIBITPATENT OWNER

Bendich A, Olson JA (1989) Biological actions of carotenoids

Nov 18, 2022EXHIBITPATENT OWNER

Block G, Patterson B, Subar A (1992) Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence

Nov 18, 2022EXHIBITPATENT OWNER

Michaud DS, Feskanich D, Rimm EB, Colditz GA, Speizer FE, Willett WC, Giovannucci E (2000) Intake of specific carotenoids and risk of lung cancer in 2 prospective US cohorts.

Nov 18, 2022EXHIBITPATENT OWNER

Correspondence, Beta Carotene, Vitamin E, and Lung Cancer

Nov 18, 2022EXHIBITPATENT OWNER

Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Jr., Valanis B, Williams JH, Jr., Barnhart S, Cherniack MG, Brodkin CA, Hammar S (1996) Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial.

Nov 18, 2022EXHIBITPATENT OWNER

Patent Owner's Power of Attorney

Sep 6, 2022PAPERPATENT OWNER

Patent Owner's Mandatory Notice

Sep 6, 2022PAPERPATENT OWNER

Notice: Notice filing date accorded

Aug 26, 2022PAPERBOARD

U.S. Patent No. 11,173,133

Aug 19, 2022EXHIBITPETITIONER

File History for U.S. Patent No. 11,173,133

Aug 19, 2022EXHIBITPETITIONER

File History for Provisional Application No. 60/453,522

Aug 19, 2022EXHIBITPETITIONER

File History for Provisional Application No. 60/435,522

Aug 19, 2022EXHIBITPETITIONER

Transaction History for Provisional Application No. 60/435,522

Aug 19, 2022EXHIBITPETITIONER

Status of Provisional Application No. 60/435,522

Aug 19, 2022EXHIBITPETITIONER

Excerpt of File History for U.S. Patent No. 9,192,586

Aug 19, 2022EXHIBITPETITIONER

FAO, Tocopherol Concentrate, Mixed, U.N. (1986)

Aug 19, 2022EXHIBITPETITIONER

WO 2001/019383 (Lang)

Aug 19, 2022EXHIBITPETITIONER

U.S. Patent No. 6,582,721

Aug 19, 2022EXHIBITPETITIONER

WO 2003/063848 (Barker)

Aug 19, 2022EXHIBITPETITIONER

U.S. Patent No. 5,747,544 (Garnett)

Aug 19, 2022EXHIBITPETITIONER

WO 2002/047493

Aug 19, 2022EXHIBITPETITIONER

Nicholas A. Phelps Brown et al., Nutrition supplements and the eye, 12 EYE 127 (1998) (Brown)

Aug 19, 2022EXHIBITPETITIONER

D. Max Snodderly, Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins, 62(suppl) AM. J. CLIN. NUTR. 1448S (1995)

Aug 19, 2022EXHIBITPETITIONER

Takashi Maoka et al., The First Isolation of Enantiomeric and Meso-Zeaxanthin in Nature, 83B COMP. BIOCHEM. PHYSIOL. 121 (1986)

Aug 19, 2022EXHIBITPETITIONER

Jeff C. Evans et al., Optimal Tocopherol Concentrations to Inhibit Soybean Oil Oxidation, 79 J. OF THE AM. OIL CHEMISTS��� SOC���Y 47 (2002)

Aug 19, 2022EXHIBITPETITIONER

Joachim Paust, Technical Syntheses, in 2 CAROTENOIDS 259 (George Britton et al. eds., 1996)

Aug 19, 2022EXHIBITPETITIONER

THE MERCK INDEX: AN ENCYCLOPEDIA OF CHEMICALS, DRUGS, AND BIOLOGICALS (Maryadele J. O���Neil et al. eds., 13th ed. 2001) (excerpt)

Aug 19, 2022EXHIBITPETITIONER

FAO, Zeaxanthin: Chemical and Technical Assessment (CTA), U.N. (2004)

Aug 19, 2022EXHIBITPETITIONER

Declaration of Elizabeth J. Johnson, Ph.D.

Aug 19, 2022EXHIBITPETITIONER

Anita M. Van der Hagen, et al., Free Radicals and Antioxidant Supplementation: A Review of Their Roles in Age-Related Macular Degeneration, 64 J. AM. OPTOMETRIC ASS'N 871 (1993)

Aug 19, 2022EXHIBITPETITIONER

Johanna M. Seddon, et al., Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration, 272 J. OF AM. MED. ASS���N 1413 (1994)

Aug 19, 2022EXHIBITPETITIONER

Norman I. Krinsky, et al., Biologic Mechanisms of the Protective Role of Lutein and Zeaxanthin in the Eye, 23 ANN. REV. NUTR. 171 (2003)

Aug 19, 2022EXHIBITPETITIONER

Thomas G. Guilliams, ed., Free Radicals, Antioxidants and Eye Diseases, 2 THE STANDARD (1999)

Aug 19, 2022EXHIBITPETITIONER

WEBSTER���S NINTH NEW COLLEGIATE DICTIONARY (9th ed. 1991) (Excerpt)

Aug 19, 2022EXHIBITPETITIONER

AREDS Report No. 8, 119 ARCH OPHTHALMOLOGY 1417 (2001)

Aug 19, 2022EXHIBITPETITIONER

AREDS Report No. 9, 119 ARCH OPHTHALMOLOGY 1439 (2001)

Aug 19, 2022EXHIBITPETITIONER

Elizabeth J. Johnson, et al., Nutritional Manipulation of Primate Retinas, III: Effects of Lutein or Zeaxanthin Supplementation on Adipose Tissue and Retina of Xanthophyll-Free Monkeys, 46 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCI. 692 (2005)

Aug 19, 2022EXHIBITPETITIONER

Maggie B. Covington, Omega-3 Fatty Acids, 70 AMERICAN FAMILY PHYSICIAN 133 (2004)

Aug 19, 2022EXHIBITPETITIONER

Hadi Moini, et al., Antioxidant and Prooxidant Activities of ��-Lipoic Acid and Dihydrolipoic Acid, 182 TOXICOLOGY AND APPLIED PHARMACOLOGY 84 (2002)

Aug 19, 2022EXHIBITPETITIONER

Fish Oil Monograph, 5 ALTERNATIVE MED. REVIEW 576 (2000)

Aug 19, 2022EXHIBITPETITIONER

ZeaVision, LLC v. Bausch & Lomb Inc., No. 4:21-cv-01352 (E.D. Mo.), D.I. 1 (Zeavision II)

Aug 19, 2022EXHIBITPETITIONER

U.S. Patent No. 9,192,586

Aug 19, 2022EXHIBITPETITIONER

Lee M. Jampol, Antioxidants, zinc, and age-related macular degeneration, 119 ARCH OPHTHALMOLOGY, 1533 (2001) (Jampol)

Aug 19, 2022EXHIBITPETITIONER

Billy R. Hammond, et al., Cigarette smoking and retinal carotenoids: Implications for age-related macular degeneration, 36 VISION RESEARCH 3003 (1996)

Aug 19, 2022EXHIBITPETITIONER

Leslie Hyman & Rebecca Nebrosky, Risk factors for age-related macular degeneration: An update, 13 CURRENT OPINION OPHTHALMOLOGY 171 (2002)

Aug 19, 2022EXHIBITPETITIONER

Susan T. Mayne, Beta-carotene, carotenoids, and disease prevention in humans, 10 FASEB J 690 (1996)

Aug 19, 2022EXHIBITPETITIONER

Christopher W. Lievens, An update on AREDS, 140 REVIEW OF OPTOMETRY, 91 (2003)

Aug 19, 2022EXHIBITPETITIONER

Lee M. Jampol, AREDS ��� Two years later, 121 ARCH OPHTHALMOLOGY, 1634 (2003)

Aug 19, 2022EXHIBITPETITIONER

AREDS2 Research Group, Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration ��� The age-related eye disease study 2 (AREDS2) randomized clinical trial, 309 JAMA 2005 (2013)

Aug 19, 2022EXHIBITPETITIONER

Bausch's Power of Attorney

Aug 19, 2022PAPERPETITIONER

Petition for Inter Partes Review of U.S. Patent No. 11,173,133

Aug 19, 2022PAPERPETITIONER