The detailed information for PTAB case with proceeding number IPR2023-00442 filed by Samsung Bioepis Co., Ltd. against Regeneron Pharmaceuticals, Inc. on Jan 6, 2023. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Case Details

Proceeding Number
IPR2023-00442
Filing Date
Jan 6, 2023
Petitioner
Samsung Bioepis Co., Ltd.
Respondent
Regeneron Pharmaceuticals, Inc.
Status
Final Written Decision
Respondent Application Number
15471506
Respondent Tech Center
1600
Respondent Patent Number
10130681
Institution Decision Date
Jul 19, 2023
Termination Date
Jun 14, 2024

Proceeding Documents

The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.


Document NameFiling DateCategoryFiling Party

Alert me when new update on this case

Dismissing in Part and Denying in Part Patent Ownerโ€™s Motion to Exclude Evidence 37 C.F.R. ยง 42.64(c) Determining Challenged Claims 1, 3โ€“11, 13, 14, 16โ€“24, and 26 Unpatentable 35 U.S.C. ยง 318(a)

Jun 14, 2024PAPERBOARD

Other: Hearing transcript

May 20, 2024PAPERBOARD

Exhibit 3002

Apr 29, 2024EXHIBITBOARD

Exhibit 3001

Apr 18, 2024EXHIBITBOARD

Petitioner's Objections to Patent Owner's Demonstratives

Apr 17, 2024PAPERPETITIONER

Patent Owner's Statement of Objections to Petitioner's Demonstratives

Apr 17, 2024PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

Apr 16, 2024PAPERPATENT OWNER

Ex. 2388 - Patent Owner's Demonstratives for Oral Hearing

Apr 16, 2024EXHIBITPATENT OWNER

Petitioner's Updated Exhibit List

Apr 16, 2024PAPERPETITIONER

Ex. 1083 - Petitioner's Demonstratives for Oral Hearing

Apr 16, 2024EXHIBITPETITIONER

Patent Owner's Reply to Opposition to Motion to Exclude

Apr 12, 2024PAPERPATENT OWNER

Petitioner's Opposition to Patent Owner's Motion to Exclude

Apr 5, 2024PAPERPETITIONER

Ex. 1082 - ASM Standard, PTAB-IPR2019-00369, Exhibit 1014

Apr 5, 2024EXHIBITPETITIONER

ORDER Setting Oral Argument

Apr 2, 2024PAPERBOARD

Patent Owner's Motion to Exclude

Mar 29, 2024PAPERPATENT OWNER

Patent Owner's Sur-Reply

Mar 11, 2024PAPERPATENT OWNER

Joint Request for Oral Argument

Mar 8, 2024PAPERPETITIONER

Patent Owner's Amended Mandatory Notices

Feb 14, 2024PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

Feb 9, 2024PAPERPATENT OWNER

Memorandum Opinion, N.D.W. Va.

Feb 9, 2024EXHIBITPATENT OWNER

Patent Owner's Second Set of Objections to Petitioner's Exhibits

Jan 23, 2024PAPERPATENT OWNER

Ex. 1068 681 FWD

Jan 16, 2024EXHIBITPETITIONER

Ex. 1069 Do Tr. IPR2022-01225

Jan 16, 2024EXHIBITPETITIONER

Ex. 1070 Do Tr.

Jan 16, 2024EXHIBITPETITIONER

Ex. 1071 ANCHOR Eligibility Criteria

Jan 16, 2024EXHIBITPETITIONER

Ex. 1072 MARINA Eligibility Criteria

Jan 16, 2024EXHIBITPETITIONER

Ex. 1073 Brown Tr.

Jan 16, 2024EXHIBITPETITIONER

Ex. 1075 Manning Tr. IPR2022-01225

Jan 16, 2024EXHIBITPETITIONER

Ex. 1076 Manning Tr.

Jan 16, 2024EXHIBITPETITIONER

Ex. 1077 Manning Tr. IPR2021-00881

Jan 16, 2024EXHIBITPETITIONER

Ex. 1078 Eylea Label 2016

Jan 16, 2024EXHIBITPETITIONER

Ex. 1079 Regeneron 2022 Press Release

Jan 16, 2024EXHIBITPETITIONER

Ex. 1080 WHO 2006

Jan 16, 2024EXHIBITPETITIONER

Ex. 1081 Klibanov Tr.

Jan 16, 2024EXHIBITPETITIONER

Ex. 1074 Brown Tr. IPR2022-01225

Jan 16, 2024EXHIBITPETITIONER

Reply

Jan 16, 2024PAPERPETITIONER

Joint Notice of Stipulation to Modify Schedule

Jan 10, 2024PAPERPETITIONER

Amended Mandatory Notices

Jan 4, 2024PAPERPETITIONER

Amended Power of Attorney

Dec 20, 2023PAPERPETITIONER

ORDER Conditionally Granting Petitionerโ€™s Motion for Admission Pro Hac Vice of Sarah M. Cork 37 C.F.R. ยง 42.10(c)

Dec 19, 2023PAPERBOARD

Joint Notice of Stipulation to Modify Schedule

Dec 14, 2023PAPERPETITIONER

Notice of Deposition of Alexander M. Klibanov

Dec 13, 2023PAPERPETITIONER

Pro Hac Vice Motion to Admit Sarah M. Cork

Dec 8, 2023PAPERPETITIONER

Cork Declaration ISO PHV Motion

Dec 8, 2023EXHIBITPETITIONER

Notice of Deposition of Richard Manning

Dec 1, 2023PAPERPETITIONER

Notice of Deposition of David M. Brown

Dec 1, 2023PAPERPETITIONER

Notice of Deposition of Diana V. Do

Dec 1, 2023PAPERPETITIONER

Patent Owner's Amended Mandatory Notices

Nov 16, 2023PAPERPATENT OWNER

ORDER Granting Patent Ownerโ€™s Unopposed Motion for Entry of Default Protective Order 37 C.F.R. ยง 42.54

Nov 2, 2023PAPERBOARD

ORDER Conditionally Granting Petitionerโ€™s Motions for Admission pro hac vice of Zachariah Summers and Elliot Choi 37 C.F.R. ยง 42.10(c)

Nov 1, 2023PAPERBOARD

Patent Owner's Motion to Seal

Oct 13, 2023PAPERPATENT OWNER

Patent Owner's Response

Oct 13, 2023PAPERPATENT OWNER

Ex. 2002 - Diana Do CV

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2024 - Shams US Publication 2007_0190058

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2025 - Macugen Drug Label Dec. 2004

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2032 - Regeneron Press Release Feb. 14, 2013

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2033 - Regeneron Press Release Feb. 6, 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2034 - FiercePharma 2021

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2035 - CDER Statistical Review

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2037 - Regeneron ATU Sales Share Data - Wet AMD

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2038 - Regeneron ATU Sales Share Data - DME

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2039 - Eylea Marketing Material Nov. 2013 part 1 of 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2039 - Eylea Marketing Material Nov. 2013 part 2 of 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2040 - Regeneron Earnings Call Transcript Feb. 13, 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2055 - Brown Declaration

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2056 - Do Declaration

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2057 - Klibanov Declaration

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2058 - Manning Declaration

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2059 - [CONFIDENTIAL] Manning Declaration with Attachments from IPR2021-00881

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2059 - [REDACTED] Manning Declaration with Attachments from IPR2021-00881

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2060 - Brown CV

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2061 - Klibanov CV

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2062 - Excerpts from Oxford Shorter Dictionary

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2063 - Eylea Prescribing Information

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2064 - Eylea Approval Letter

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2065 - Biochemistry 2002 5 ed

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2066 - Organic Chemistry 4th ed Chap 27 Part 1 of 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2066 - Organic Chemistry 4th ed Chap 27 Part 2 of 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2067 - Hirokawa 1988

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2068 - Prange 1998

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2069 - Mihailescu 2001

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2070 - Beek 2002

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2071 - Handgraaf 2006

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2072 - Yu 2010

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2073 - Scott 2004

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2074 - Kleiger 2000

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2075 - Demarest 2004

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2076 - Cantu 2010

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2077 - Biochemistry 6th ed Chap 7 Part 1 of 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2077 - Biochemistry 6th ed Chap 7 Part 2 of 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2078 - Davis-Smyth 1996

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2079 - UNIPROT - P17948 VGFR1 Human

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2080 - UNIPROT - P17948 v140 -2011-01-11

Oct 13, 2023EXHIBITPATENT OWNER

EX. 2081 - Weissmann 1997

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2082 - Lu 2000

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2083 - Franklin 2011

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2084 - UNIPROT - P35968 VGFR2 Human

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2085 - UNIPROT - P35968 v127 -2011-01-11

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2086 - Bowie 1990

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2087 - US Pub 2006_0058234 A1

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2088 - lacono 2010

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2089 - Stewart & Rosenfeld 2008

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2090 - Do 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2091 - Moroney 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2092 - US Pub 2010_0160233 A1

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2093 - Hachiya 2007

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2094 - Piques 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2095 - WO 2000_075319 A1

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2102 - Wells 2015

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2103 - [CONFIDENTIAL] REGN Research Collaboration Agreement Template

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2104 - [CONFIDENTIAL] Marmoset Pregnancy Study Email

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2109 - Rosenfeld 2006

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2110 - Genentech Press Release Dec. 30, 2005

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2112 - NCT00473330

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2113 - NCT00473382

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2114 - NCT00486018

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2115 - NCT00485836

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2116 - NCT00943072

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2117 - NCT01012973

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2118 - FDA Non-Inferiority Clinical Trials

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2119 - May 2016 Eylea Label

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2121 - Jaffe 2016

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2126 - BenEzra 2005

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2128 - Adamis Chapter 4

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2129 - Brown 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2130 - Gragoudas 2004

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2134 - Regeneron Earnings Call Tr Apr 26, 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2135 - Regeneron Earnings Call Tr July 25, 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2136 - Eylea Marketing Material, 2013

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2138 - [CONFIDENTIAL] Regeneron Physician ATU Wave 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2139 - Regeneron For the Treatment of Wet AMD, 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2140 - [CONFIDENTIAL] Regeneron Physician ATU Wave 5

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2141 - Am. Acad. of Ophthalmol. - Anti-VEGF Treatments

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2142 - Am. Acad. of Ophthalmol. - Bevacizumab

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2143 - Am. Acad. of Ophthalmol. - Ophthalmology Subspecialists

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2144 - Am. Acad. of Ophthalmol. - Retinal Vasculitis

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2145 - Am. Acad. of Ophthalmol. - What Is Avastin

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2146 - Am. Acad. of Ophthalmol. - What Is Eylea

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2147 - Am. Acad. of Ophthalmol. - What Is Lucentis

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2148 - Am. Soc. of Retina Specialists - About Us

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2149 - Am. Soc. of Retina Specialists - Age-Related Macular Degeneration

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2150 - Am. Soc. of Retina Specialists - Branch Retinal Vein Occlusion

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2151 - Am. Soc. of Retina Specialists - Central Retinal Vein Occlusion

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2152 - Am. Soc. of Retina Specialists - Diabetic Retinopathy

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2153 - Amgen - Fusion Protein

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2154 - ASHA - Calculating Medicare Fee Schedule Rates

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2155 - ASPE Issue Brief - Medicare Part B Reimbursement of Prescription Drugs

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2157 - Base Pair Biotechnologies - What is an Aptamer

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2158 - Bausch and Lomb Website - Visudyne

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2159 - Bausch and Lomb Website - Visudyne Saftey Information

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2160 - Bausch Health Companies 10-K, 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2161 - Beovu Drug Label Oct. 2019

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2162 - Beovu Drug Label June 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2163 - [CONFIDENTIAL] Regeneron Physician ATU Wave 4

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2164 - BrightFocus Foundation - AMD Facts & Figures

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2165 - Brookings - Medicare Payment for Physician-Administered (Part B) Drugs

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2166 - Calculator.net - Sample Size Calculator

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2167 - CDC - Vision Loss - A Public Health Problem

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2168 - Centers for Medicare & Medicaid Services Data - Practitioners

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2169 - [CONFIDENTIAL] Eylea Sample Disbursement Part 1 of 3

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2169 - [CONFIDENTIAL] Eylea Sample Disbursement Part 2 of 3

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2169 - [CONFIDENTIAL] Eylea Sample Disbursement Part 3 of 3

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2170 - [CONFIDENTIAL] US Eylea P&L

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2170 - [REDACTED] US Eylea P&L

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2171 - CloudResearch - Determining Sample Size

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2172 - CMS - 2021 ASP Drug Pricing Files

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2173 - CMS - Medicare Part B Drug Average Sales Price

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2174 - CMS - Physician Fee Schedule

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2175 - CMS Medicare Coverage Database - Billing and Coding Afilbercept

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2176 - [CONFIDENTIAL] Regeneron Q4 Performance Update

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2177 - Donahue 2007

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2178 - Donohue 2004

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2179 - Dreyfuss 2015

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2180 - Miller 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2181 - Drugs.com - Eylea FDA Approval History

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2182 - Elyasi 2021

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2183 - Eye Care Surgery Center - Macular Degeneration

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2184 - EyeGuru - Intravitreal Injection Standard Dosing Table

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2186 - Eylea Drug Label Sept. 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2187 - Eylea Drug Label Oct. 2014

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2188 - Eylea Drug Label May 2019

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2189 - Eylea Drug Label Mar. 2021

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2190 - Eylea Website - Dosing Flexibility for Wet AMD

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2191 - FDA Website - Drug Approval Package Macugen

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2192 - FiercePharma - Beovu, Novartis

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2193 - FiercePharma - Novartis Drug Beovu Tied to Potential Vision Loss

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2194 - FiercePharma - The top 20 drugs by worldwide sales in 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2195 - FocusVision - Survey Sample Size How Much Do I Need

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2196 - Gagnon 2008

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2197 - [CONFIDENTIAL] Eylea Physician ATU Benchmark Wave

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2198 - GEN - FDA Green-Lights Genentechs Lucentis

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2199 - Genentech Press Release June 30, 2006

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2200 - [CONFIDENTIAL] Regeneron US Eylea Historical PL

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2200 - [REDACTED] Regeneron US Eylea Historical PL

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2201 - Guha 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2202 - HCPCS Codes - HCPCS Codes

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2203 - Healio - Access to retina providers shows no geographic bias in US

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2204 - Hopkins Medicine Website - Photodynamic Therapy for AMD

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2205 - [CONFIDENTIAL] Eylea DME Market Assessment

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2206 - IQVIA 10-K 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2207 - IQVIA - Available IQVIA Data

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2208 - [CONFIDENTIAL] Eylea ATU Wave 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2209 - KFF - A Snapshot of Sources

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2210 - KFF - Medicare Advantage in 2021

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2211 - Ling 2002

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2212 - Lucentis Drug Label 2006

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2213 - Lucentis Drug Label June 2010

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2214 - Lucentis Drug Label Aug. 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2215 - Lucentis Drug Label Apr. 2017

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2216 - Lucentis Drug Label Mar. 2018

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2218 - [CONFIDENTIAL] Eylea Components of Reimbursement

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2218 - [REDACTED] Eylea Components of Reimbursement

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2219 - Mankiw Chapter 1

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2220 - Manning 2015

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2221 - Mayo Clinic - Wet macular degeneration - Diagnosis and treatment

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2222 - Mayo Clinic - Wet macular degeneration - Symptoms and Causes

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2223 - Medicare Interactive - Medicare Part B Covered Services

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2224 - Medicare Interactive - The parts of Medicare (A, B, C, D)

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2225 - Medicare.gov - Macular Degeneration Coverage

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2226 - Medicare.gov - Medicare Advantage Plans

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2227 - Medicare.gov - When does Medicare coverage start

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2228 - MedlinePlus Medical Encyclopedia - Laser photocoagulation

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2229 - [CONFIDENTIAL] Regeneron WAC Pricing

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2230 - Novartis - Annual Report, 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2231 - Novartis Press Release Oct. 8, 2019

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2232 - Novartis Press Release June 11, 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2233 - Oct 2012 ASP Pricing File revised 060513

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2234 - Oct 2013 ASP Pricing File updated 060614

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2235 - Oct 2015 ASP Pricing File - updated 120915

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2236 - Oct 2016 ASP Pricing File updated 082817

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2237 - Oct 2017 ASP Pricing File 083017

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2238 - Oct 2018 ASP Pricing File updated 052919

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2239 - Oct 2019 ASP Pricing File 052920

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2240 - Oct 2014 ASP Pricing File - revised 090115

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2241 - Oct 2020 ASP Pricing File updated 090121

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2242 - Oct 2021 ASP Pricing File updated 011022

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2243 - [CONFIDENTIAL] ASRS Preferences & Trends Survey 2016

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2244 - [CONFIDENTIAL] ASRS Preferences & Trends Survey 2015

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2245 - Pindyck Chapter 3

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2246 - Regeneron - About Us

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2247 - Regeneron Press Release July 29, 2014

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2248 - Regeneron Press Release Oct. 6, 2014

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2249 - Regeneron Press Release May 13, 2019

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2250 - [CONFIDENTIAL] ASRS Prefernces & Trends Survey 2014

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2251 - Regeneron - History

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2252 - Regeneron Press Release Sept. 21, 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2253 - Regeneron - Research Areas

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2254 - Regeneron Form 10-K for 2020 Part 1 of 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2254 - Regeneron Form 10-K for 2020 Part 2 of 2

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2255 - Retinal Physician - Revisiting an Early Treatment for Wet AMD

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2256 - Roche 10-K, 2020

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2257 - Roche Press Release Aug. 13, 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2258 - Roche Press Release Apr. 18, 2017

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2259 - [CONFIDENTIAL] ASRS Preferences & Trends Survey 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2260 - Schweitzer Chapter 4

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2261 - ScienceDaily - FDA Approves First Angiogenesis Inhibitor

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2262 - Sivaprasad 2021

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2263 - [CONFIDENTIAL] Eylea Sales Summary

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2264 - Verywell Health - Macular Degeneration Timeline

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2265 - Vestrum Health - Explore what we can do for you

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2266 - Vestrum Health - Pharmaceutical companies

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2267 - Visudyne Drug Label Apr 2016

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2268 - Weidner 2021

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2269 - WHO - Blindness and vision impairment

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2270 - Yahoo Finance - Beovu Now Publicly Reimbursed

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2271 - Yorston 2014

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2272 - [CONFIDENTIAL] Eylea Q2 2021 Performance

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2273 - [CONFIDENTIAL] Vestrum Anti-VEGF Category Sales Shares

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2274 - [CONFIDENTIAL] Eylea Wet AMD Line of Therapy Insights

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2275 - [CONFIDENTIAL] Vestrum Anti-VEGF Market Share Adjustment

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2276 - [CONFIDENTIAL] Eylea Q2 2020 Performance

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2277 - [CONFIDENTIAL] Regeneron Marketing Planning Process

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2278 - [CONFIDENTIAL] Regeneron Wave 1 2021 Performance Update

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2279 - Regeneron ATU Sales Share Data - All Indications

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2282 - Regeneron ATU Sales Share Data - CRVO

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2283 - Regeneron ATU Sales Share Data - BRVO

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2284 - Regeneron ATU Sales Share Data - DR without DME

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2285 - [CONFIDENTIAL] Eylea Gross & Net Sales P&L

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2285 - [REDACTED] Eylea Gross & Net Sales P&L

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2289 - Retinal Physician Symposium

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2290 - Lucentis Label 2006

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2293 - Margolis 2010

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2295 - Spaide 2007

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2296 - Brown 2011

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2297 - Heier 2011

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2298 - [CONFIDENTIAL] Research Agreement

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2299 - [CONFIDENTIAL] VGFT-OD-0605 Protocol Signature Page

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2300 - Eylea P I

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2301 - Regeneron Corrected Press Release Nov. 18, 2011

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2302 - Eylea Approval Letter

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2303 - Bhisitkul & Stewart 2010

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2304 - FDA 22 Case Studies

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2305 - NCT02247531

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2306 - NCT02247479

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2307 - NCT03577899

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2308 - NCT03630952

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2309 - NCT01944839

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2310 - NCT01940900

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2311 - Mathis 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2312 - Cousins 2010

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2313 - Helzner 2007

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2314 - FDA Guidance -Expedited Programs

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2315 - NCT01486771

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2316 - Gallemore 2008

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2317 - Kanghong Press Release - Translation

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2318 - Kanghong Press Release - Chinese

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2319 - Thomas 2013

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2320 - Ohr 2012

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2321 - FDA Approves Eylea for Wet AMD

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2332 - Ophthotech Press Release, Dec. 12, 2016

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2333 - Genentech Press Release, Nov. 9, 2017

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2334 - Ciulla & Rosenfeld 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2360 - Order On Claim Construction, DN 427, N.D.W. Va.

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2361 - Regeneron Press Release, May 8, 2008

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2362 - Heier 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2363 - Ni 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2364 - Fung 2007

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2365 - Lalwani 2009

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2366 - Retina Society Meeting Presentation

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2368 - Toy MACTEL paper

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2369 - HHS - Approval of Research with Conditions, OHRP Guidance (2010)

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2370 - pegaptanib VISION

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2371 - Getz 2011

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2372 - Buyse 2016

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2375 - Am. Acad. of Ophthalmol. - What Is Macular Telangiectasia

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2376 - Basic and Clinical Science Course, Sec. 9, Ch. 9

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2377 - Mueller 2008

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2378 - Pathobiology of Ocular Disease, Ch. 3

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2379 - Caspi 2010

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2380 - Bodaghi 2001

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2381 - Mayo Clinic - Stye (sty) - Symptoms & causes

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2382 - Bos Childrens Hosp - Orbital Cellulitis (Periorbital Cellulitis)

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2383 - Fundamentals of Clinical Trials, Ch. 4

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2384 - Deposition of Edward Chaum

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2385 - FDA.gov - Step 3 - Clinical Research

Oct 13, 2023EXHIBITPATENT OWNER

Ex. 2386 - Excerpt from Webster's Dictionary

Oct 13, 2023EXHIBITPATENT OWNER

Patent Owner's Unopposed Motion for Entry of Default Protective Order

Oct 6, 2023PAPERPATENT OWNER

Pro Hac Vice Motion to Admit Zach Summers

Sep 26, 2023PAPERPETITIONER

Summers Declaration ISO PHV Motion

Sep 26, 2023EXHIBITPETITIONER

Pro Hac Vice Motion to Admit Elliot Choi

Sep 26, 2023PAPERPETITIONER

Choi Declaration ISO PHV Motion

Sep 26, 2023EXHIBITPETITIONER

Amended Notice of Deposition of Edward Chaum

Sep 21, 2023PAPERPATENT OWNER

ORDER Granting Patent Owners Motions for Admission Pro Hac Vice of Abigail Struthers, Jeremy Cobb, Victoria Reines, and Matthew Wilk 37 C.F.R. ยง 42.10 c

Aug 17, 2023PAPERBOARD

Patent Owner's Notice of Deposition of Edward Chaum

Aug 15, 2023PAPERPATENT OWNER

Patent Owner's Amended Mandatory Notices

Aug 3, 2023PAPERPATENT OWNER

Patent Owner's Objections to Petitioner's Exhibits

Aug 2, 2023PAPERPATENT OWNER

Patent Owner's Updated Exhibit List

Jul 28, 2023PAPERPATENT OWNER

Pro Hac Vice Motion to Admit Abigail Struthers

Jul 28, 2023PAPERPATENT OWNER

Ex. 2050 - Declaration of Abigail Struthers

Jul 28, 2023EXHIBITPATENT OWNER

Pro Hac Vice Motion to Admit Jeremy Cobb

Jul 28, 2023PAPERPATENT OWNER

Ex. 2052 - Declaration of Jeremy Cobb

Jul 28, 2023EXHIBITPATENT OWNER

Pro Hac Vice Motion to Admit Victoria Reines

Jul 28, 2023PAPERPATENT OWNER

Ex. 2053 - Declaration of Victoria Reines

Jul 28, 2023EXHIBITPATENT OWNER

Pro Hac Vice Motion to Admit Matthew Wilk

Jul 28, 2023PAPERPATENT OWNER

Ex. 2054 - Declaration of Matthew Wilk

Jul 28, 2023EXHIBITPATENT OWNER

Granting Institution of Inter Partes Review 35 U.S.C. 314

Jul 19, 2023PAPERBOARD

SCHEDULING ORDER

Jul 19, 2023PAPERBOARD

Patent Owner's Sur-Reply to Petitioner's Reply to POPR

May 24, 2023PAPERPATENT OWNER

Petitioner's Reply to POPR

May 17, 2023PAPERPETITIONER

Ex 1064 Board's May 11, 2023 Email

May 17, 2023EXHIBITPETITIONER

Preliminary Response of Patent Owner

Apr 25, 2023PAPERPATENT OWNER

Ex. 2021 - Albini January Deposition Transcript

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2106 - Macugen Approval Letter

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2107 - 2004 Macugen Label

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2108 - NCT00473330

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2111 - Genentech Press Release June 30, 2006

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2120 - Am Acad Opthalmolgy - Sect 9, Chap 6

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2131 - Regillo 2008

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2132 - Levine 2009

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2156 - Avastin Drug Label 2004

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2185 - Eylea Drug Label Nov. 2011

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2286 - Abraham 2010

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2287 - Barbazetto 2010

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2288 - Cruz 2006

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2291 - Schmidt-Erfuth 2011

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2292 - Boyer 2009

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2294 - Park 2012

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2345 - NCT00056836

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2346 - NCT00061594

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2347 - Lucentis MR

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2348 - NCT00090623

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2349 - Mitchell

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2351 - Christensen

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2352 - NCT00685854

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2353 - CATT

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2354 - Bhatt

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2355 - Eylea MR

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2356 - NCT-377

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2357 - Motion for Joinder, IPR2023-00566

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2358 - N C T-795

Apr 25, 2023EXHIBITPATENT OWNER

Ex. 2359 - Biotechnology Fundamentals 3d Ed, Ch 11

Apr 25, 2023EXHIBITPATENT OWNER

Notice : Power of Attorney

Feb 14, 2023PAPERPETITIONER

Notice : Power of Attorney

Jan 30, 2023PAPERPATENT OWNER

Notice : Mandatory Notice

Jan 30, 2023PAPERPATENT OWNER

Notice: Notice filing date accorded

Jan 25, 2023PAPERBOARD

Ex. 1001 - US10130681

Jan 6, 2023EXHIBITPETITIONER

Ex. 1003 - Chaum CV

Jan 6, 2023EXHIBITPETITIONER

Ex. 1004 - 338 Patent FWD

Jan 6, 2023EXHIBITPETITIONER

Ex. 1005 - NIH AMD

Jan 6, 2023EXHIBITPETITIONER

Ex. 1006 - Dixon

Jan 6, 2023EXHIBITPETITIONER

Ex. 1007 - Regeneron September 14, 2009 Press Release

Jan 6, 2023EXHIBITPETITIONER

Ex. 1008 - Halpern 2006

Jan 6, 2023EXHIBITPETITIONER

Ex. 1009 - Holash

Jan 6, 2023EXHIBITPETITIONER

Ex. 1010 - Rudge 2005

Jan 6, 2023EXHIBITPETITIONER

Ex. 1011 Gomez Manzano

Jan 6, 2023EXHIBITPETITIONER

Ex. 1012 - Adis

Jan 6, 2023EXHIBITPETITIONER

Ex. 1013 - US7531173

Jan 6, 2023EXHIBITPETITIONER

Ex. 1014 - Rudge 2007

Jan 6, 2023EXHIBITPETITIONER

Ex. 1015 - Li

Jan 6, 2023EXHIBITPETITIONER

Ex. 1016 - Heier 2012

Jan 6, 2023EXHIBITPETITIONER

Ex. 1017 - Brown 2009

Jan 6, 2023EXHIBITPETITIONER

Ex. 1018 - Martin

Jan 6, 2023EXHIBITPETITIONER

Ex. 1019 - Heier 2011

Jan 6, 2023EXHIBITPETITIONER

Ex. 1020 - Chakravarthy

Jan 6, 2023EXHIBITPETITIONER

Ex. 1021 - Rosenfeld

Jan 6, 2023EXHIBITPETITIONER

Ex. 1022 - Heimann

Jan 6, 2023EXHIBITPETITIONER

Ex. 1023 - Uveitis Fact Sheet

Jan 6, 2023EXHIBITPETITIONER

Ex. 1024 - Conjunctivitis Overview

Jan 6, 2023EXHIBITPETITIONER

Ex. 1025 - 681 patent PH

Jan 6, 2023EXHIBITPETITIONER

Ex. 1026 - Lucentis Label 2006

Jan 6, 2023EXHIBITPETITIONER

Ex. 1027 - 338 patent PH

Jan 6, 2023EXHIBITPETITIONER

Ex. 1028 - 338 patent

Jan 6, 2023EXHIBITPETITIONER

Ex. 1029 - 069 patent

Jan 6, 2023EXHIBITPETITIONER

Ex. 1031 - CATT Study

Jan 6, 2023EXHIBITPETITIONER

Ex. 1033 - MACTEL Study Wayback Machine

Jan 6, 2023EXHIBITPETITIONER

Ex. 1034 - PIER Study

Jan 6, 2023EXHIBITPETITIONER

Ex. 1035 - NCT00593450

Jan 6, 2023EXHIBITPETITIONER

Ex. 1036 - 758 patent

Jan 6, 2023EXHIBITPETITIONER

Ex. 1037 - Dix

Jan 6, 2023EXHIBITPETITIONER

Ex. 1038 - Brown 2005

Jan 6, 2023EXHIBITPETITIONER

Ex. 1039 - AAO What is a Slit Lamp

Jan 6, 2023EXHIBITPETITIONER

Ex. 1040 - Jaffe

Jan 6, 2023EXHIBITPETITIONER

Ex. 1041 - Safe Intravitreal Injection Technique

Jan 6, 2023EXHIBITPETITIONER

Ex. 1043 - Using the Wayback Machine

Jan 6, 2023EXHIBITPETITIONER

Ex. 1044 - NCT00685854 and Glossary

Jan 6, 2023EXHIBITPETITIONER

Ex. 1046 - 069 patent FWD

Jan 6, 2023EXHIBITPETITIONER

Ex. 1047 - 069 patent Institution Decision

Jan 6, 2023EXHIBITPETITIONER

Ex. 1048 - Dixon Published Date

Jan 6, 2023EXHIBITPETITIONER

Ex. 1049 - ClinicalTrials.gov Background

Jan 6, 2023EXHIBITPETITIONER

Ex. 1050 - About the Results Database

Jan 6, 2023EXHIBITPETITIONER

Ex. 1051 - How to Read a Study Record

Jan 6, 2023EXHIBITPETITIONER

Ex. 1052 - AJO PIER Study Published Date

Jan 6, 2023EXHIBITPETITIONER

Ex. 1053 - History of Changes (NCT00090623)

Jan 6, 2023EXHIBITPETITIONER

Ex. 1054 - Del Piore Decl. filed in IPR2021-00881

Jan 6, 2023EXHIBITPETITIONER

Ex. 1055 - Oral Hearing Transcript (IPR2021-00880, 881)

Jan 6, 2023EXHIBITPETITIONER

Ex. 1056 - 758 patent PH 12/22/2011 PTE

Jan 6, 2023EXHIBITPETITIONER

Ex. 1057 - Regeneron 10-Q (Sept. 30, 2009)

Jan 6, 2023EXHIBITPETITIONER

Ex. 1058 - 681 patent IPR Petition by Mylan (IPR2022-01225)

Jan 6, 2023EXHIBITPETITIONER

Ex. 1059 - Jager

Jan 6, 2023EXHIBITPETITIONER

Ex. 1060 - Regeneron Complaint

Jan 6, 2023EXHIBITPETITIONER

Ex. 1062 - Eylea Label

Jan 6, 2023EXHIBITPETITIONER

Ex. 1063 - NHS Uveitis Overview

Jan 6, 2023EXHIBITPETITIONER

Ex. 1030 - Jt. CC Chart

Jan 6, 2023EXHIBITPETITIONER

Ex. 1042 - Regeneron April 28, 2008 Press Release

Jan 6, 2023EXHIBITPETITIONER

Ex. 1045 - History of Changes (NCT00685854)

Jan 6, 2023EXHIBITPETITIONER

Ex. 1061 - Eylea Purple Book Patent List

Jan 6, 2023EXHIBITPETITIONER

Ex. 1032 - NCT00685854 (May 24, 2008)

Jan 6, 2023EXHIBITPETITIONER

Notice : Power of Attorney

Jan 6, 2023PAPERPETITIONER

Petition

Jan 6, 2023PAPERPETITIONER

Ex. 1002 - Chaum Decl.

Jan 6, 2023EXHIBITPETITIONER