Shanghai Hongene Biotech Corporation vs ChemGenes Corporation

Other: Hearing transcript

Final Written Decision: JUDGMENT Final Written Decision Determining Challenged Claims 1–5 Unpatentable Granting Petitioner’s Motion to Seal 35 U.S.C. § 318(a)

Petitioner's Oral Hearing Demonstratives

Demonstrative Exhibit

ORDER Setting Oral Argument

Patent Owner's Response to Petitioner's Motion to Seal

Exhibit 2041- Email exchange between counsel

Exhibit 2042- Email exchange between counsel

Motion to Seal

REDACTED Patent Owner Sur-Reply

REDACTED Ex. 2035

REDACTED Ex. 2036

REDACTED Ex. 2038

REDACTED Ex. 2039

PUBLIC Version of Ex. 2033

PUBLIC Version of Ex. 2034

Patent Owner's Request for Oral Argument

Email Dated March 8 & 11, 2024

Petitioner's Request for Oral Argument

Order: Conduct of the Proceeding Authorizing Patent Owners Request to Withdraw its Motion to Amend Claims 37 C.F.R. secs. 42.54, 42.121b

Exhibit 3003

Ex. 3004

Patent Owner Sur-Reply - SEALED

Baran Deposition Transcript - January 22, 2024

HONG_0000024 - SEALED

HONG_0000031-39 - SEALED

Baran Deposition Transcript - February 20, 2024 - SEALED

HONG_0000029-30 - SEALED

HONG_0000017-18 - SEALED

HONG_0000011-14 - SEALED

Order: ORDER Entry of Modified Protective Order 37 C.F.R. § 42.54

Exhibit 3002

Patent Owner Update Mandatory Disclosures

Patent Owner's Second Notice of Remote Deposition of P. Baran, Ph.D

Notice: PRELIMINARY GUIDANCE PATENT OWNERS MOTION TO AMEND

Petitioner's Reply to Patent Owner Response

EXPUNGED

Exhibit 1034 - Baran Updated CV

Exhibit 1035 - Hrdlicka Deposition Transcript

EXPUNGED

Exhibit 1033 - Baran Reply Declaration

EXPUNGED

EXPUNGED

Exhibit 1036 - DNA Synthesis Without Base Protection, Current Protocols in Nucleic Acid Chemistry (2004), 3.10-3.10.15

Exhibit 1037 - Paul Gaytán, BioTecniques 47:701-702 (August 2009)

Exhibit 1038 - Xue-Feng Zhu, et al., An Improved Transient Method for the Synthesis of N-Benzoylated Nucleosides, Synthetic Communications, 33:7, 1233-1243 (2003)

Exhibit 1039 - Todd D. Nelson, et al., Selective Deprotection of Silyl Ethers, February 26, 1996

Exhibit 1040 - M. P. Reddy, et al., Ultrafast Cleavage and Deprotection of Oligonucleotides Synthesis and Use of CAc Derivatives, Nucleosides, Nucleotides & Nucleic Acids, 16:7-9, 1589-1598, 1997

Exhibit 1041 - Dimitrios Stefanidis, et al., General Base Catalysis of Ester Hydrolysis, J. Am. Chem. Soc. 1993, 115, 6045-6050

Exhibit 1042 - Advanced Organic Chemistry, Reactions, Mechanisms, and Structure, 1992, Chapter 4, Stereochemistry, 94-164

Exhibit 1043 - U.S. Patent No. 5,525,719

Petitioner's Opposition Brief to Motion to Amend Claims

Exhibit 1044 - Baran Declaration ISO Opposition

Exhibit 1045 - US Patent No. 5,606,049

Exhibit 1046 - The Glen Report

Exhibit 1047 - US Patent No. 5,214,135

Petitioner's Notice of Deposition of Patrick J. Hrdlicka, Ph.D.

Order: REVISED SCHEDULING ORDER

Patent Owner Response

Huang et al. (2021)

Flood et al. (2020)

Flood et al. (2019)

Hogrefe (2013)

Second Amended Complaint

Dr. Hrdlicka Declaration

Dr. Baran Deposition Transcript

Knouse (2018)

Weber & Khorana (1972

Schaller et al. (1963)

Schulhof et al.

Guschlbaur & Jankowski (1980)

Ober et al. (2005)

Iyer (2000)

Koster et al. (1981)

Sinha et al. (1993)

Scaringe et al. (2004)

Buchi & Khorana (1972)

McBride et al. (1986)

Meher et al. (2017)

Culf et al. (2008)

Okafo et al. (2013)

Kawasaki et al. (1993)

ChemGenes Invoice (2004)

ChemGenes Invoice (2008)

ChemGenes Invoice (2006)

ChemGenes Catalog (1999)

ChemGenes Catalog (2009)

Pon (2000)

PATENT OWNER’S MOTION TO AMEND CLAIMS UNDER 37 C.F.R. § 42.121

Order: Conduct of the Proceeding - Dismissing Petitioner's Motion to Stay - 37 CFR 42.5

Ex. 3001

PATENT OWNER’S UPDATED MANDATORY NOTICES

Patent Owner's Notice of Remote Deposition of Phil S Baran, Ph.D

Patent Owner's Response to Petitioner's Motion to Stay the Reissue Application

Petitioner's Motion to Stay Reissue Application

Jeremy J. Edwards Declaration in Support of Petitioner's Motion to Stay

Reissue Preliminary Amendment

Petitioner's Current Exhibit List

Order: Conduct of the Proceeding Authorizing Petitioner’s Motion to Stay 37 C.F.R. § 42.54

Institution Decision: Grant

SCHEDULING ORDER

Patent Owner's Updated Mandatory Notices

Notice : Mandatory Notice

Notice : Power of Attorney

Notice: NOTICE OF FILING DATE ACCORDED TO PETITION AND TIME FOR FILING PATENT OWNER PRELIMINARY RESPONSE

Petition : as filed

Notice : Power of Attorney

Exh 1001 US9884885

Exh 1002 US9884885 FH

Exh 1003 Declaration of Phil Baran ISO Petition for Inter Partes Review

Exh 1004 Beaucage 1981

Exh 1005 Matteucci 1981

Exh 1006 McBride 1983

Exh 1007 Beaucage 1992

Exh 1008 Twist Bioscience

Exh 1009 Reese 2005

Exh 1010 Lackey 2008

Exh 1011 Ashley 1992

Exh 1012 Ohkubo 2008

Exh 1013 Scherr 1997

Exh 1014 Brown 1989

Exh 1015 Usman 2006

Exh 1016 US5808039

Exh 1017 US5898031

Exh 1018 Pitsch 2001

Exh 1019 Fan 2004

Exh 1020 US7879991

Exh 1021 Pitsch 2001 (2)

Exh 1022 Scaringe 1990

Exh 1023 Scheuer-Larsen 1997

Exh 1024 Gaur 1992

Exh 1025 Sproat 1991

Exh 1026 Inoue 1987

Exh 1027 White 1988

Exh 1028 Sivets 2007

Exh 1029 Donga 2007

Exh 1030 Usman 2003