The detailed information for PTAB case with proceeding number IPR2024-00526 filed by Bruker Spatial Biology, Inc. against 10x Genomics, Inc. et al. on Jan 30, 2024. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Case Details

Proceeding Number
IPR2024-00526
Filing Date
Jan 30, 2024
Petitioner
Bruker Spatial Biology, Inc.
Respondent
10x Genomics, Inc. et al.
Status
Terminated-Settled
Respondent Application Number
17395534
Respondent Tech Center
1600
Respondent Patent Number
11542554
Institution Decision Date
Aug 23, 2024
Termination Date
May 30, 2025

Proceeding Documents

The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.


Document NameFiling DateCategoryFiling Party

Alert me when new update on this case

Order: Granting Motion to Expunge

Jul 30, 2025PAPERBOARD

Exclusive Licensee's Motion to Expunge

Jun 20, 2025PAPERPATENT OWNER

Order: Granting Patent Owner's Motion to Seal (Paper 22) - Granting Petitioner's Motion to Seal (Paper 28) - 37 CFR 42.14, 42.54

May 30, 2025PAPERBOARD

Termination Decision: Post-DI Settlement

May 30, 2025PAPERBOARD

E-mail authorizing motion to terminate

May 29, 2025EXHIBITBOARD

E-mail regarding motion to terminate

May 29, 2025EXHIBITBOARD

Joint Request to File Collateral Agreements as Business Confidential and to Keep it Separate from the Patent Files Pursuant to 35 U.S.C. Section 317 and 37 C.F.R. Section 42.74

May 19, 2025PAPERPETITIONER

Petitioner's Updated Exhibit List

May 19, 2025PAPERPETITIONER

EX1088 [Confidential] Collateral Agreement

May 19, 2025EXHIBITPETITIONER

EX1089 [Confidential] Collateral Agreement

May 19, 2025EXHIBITPETITIONER

EX1090 [Confidential] Collateral Agreement

May 19, 2025EXHIBITPETITIONER

Joint Motion to Terminate Pursuant to 35 U.S.C. Section 317 and 37 C.F.R. Section 42.74

May 14, 2025PAPERPETITIONER

Joint Request to File Settlement Agreement as Business Confidential and to Keep it Separate from the Patent Files Pursuant to 35 U.S.C. Section 317 and 37 C.F.R. Section 42.74

May 14, 2025PAPERPETITIONER

Petitioner's Updated Exhibit List

May 14, 2025PAPERPETITIONER

EX1087 {Confidential] Settlement Agreement

May 14, 2025EXHIBITPETITIONER

Exclusive Licensee's Updated Exhibit List

May 13, 2025PAPERPATENT OWNER

EX2086 - Exclusive Licensee's Demonstratives

May 13, 2025EXHIBITPATENT OWNER

Petitioner's Oral Hearing Presentation

May 13, 2025PAPERPETITIONER

Exclusive Licensee's Updated Power of Attorney

May 5, 2025PAPERPATENT OWNER

EX2084 - Ehrlich PHV Declaration

May 5, 2025EXHIBITPATENT OWNER

Exclusive Licensee's Notice of Intent to Designate Provisionally Recognized PTAB Attorneys

May 5, 2025PAPERPATENT OWNER

EX2085 - Powers PHV Declaration

May 5, 2025EXHIBITPATENT OWNER

ORDER Setting Oral Argument 37 C.F.R. § 42.70

Apr 28, 2025PAPERBOARD

Patent Owner's Sur-Reply

Apr 25, 2025PAPERPATENT OWNER

Transcript of Deposition of Czymmek

Apr 25, 2025EXHIBITPATENT OWNER

Patent Owner's Response to Petitioner's Motion to Seal Exhibit 1083

Apr 18, 2025PAPERPATENT OWNER

EX2083 - Davis Deposition Transcript (PUBLIC - REDACTED)

Apr 18, 2025EXHIBITPATENT OWNER

e-mail to the parties

Apr 17, 2025EXHIBITBOARD

Petitioner's Updated Mandatory Notice

Apr 15, 2025PAPERPETITIONER

Patent Owner's Request for Oral Argument

Apr 4, 2025PAPERPATENT OWNER

Petitioner's Request for Oral Argument

Apr 4, 2025PAPERPETITIONER

Patent Owner's Notice of Deposition

Apr 3, 2025PAPERPATENT OWNER

Petitioner Reply to Patent Owner's Response

Mar 18, 2025PAPERPETITIONER

EX 1073 US 12,209,327

Mar 18, 2025EXHIBITPETITIONER

EX 1074 Trcek 2017

Mar 18, 2025EXHIBITPETITIONER

EX 1075 York 2011

Mar 18, 2025EXHIBITPETITIONER

EX 1076 Lakdawala 2014

Mar 18, 2025EXHIBITPETITIONER

EX 1077 Battich 2013

Mar 18, 2025EXHIBITPETITIONER

EX 1078 Supplemental Battich

Mar 18, 2025EXHIBITPETITIONER

EX 1079 Supplemental Battich

Mar 18, 2025EXHIBITPETITIONER

EX 1080 CosMx

Mar 18, 2025EXHIBITPETITIONER

EX 1081 Cancer Research

Mar 18, 2025EXHIBITPETITIONER

EX 1082 Shroff

Mar 18, 2025EXHIBITPETITIONER

EX 1083 Davis

Mar 18, 2025EXHIBITPETITIONER

EX 1084 3D microscopy

Mar 18, 2025EXHIBITPETITIONER

EX 1085 Chen 2015

Mar 18, 2025EXHIBITPETITIONER

EX 1086 Czymmek Reply Dec

Mar 18, 2025EXHIBITPETITIONER

Motion to Seal Ex. 1083

Mar 18, 2025PAPERPETITIONER

Petitioner's Updated Mandatory Notices

Feb 25, 2025PAPERPETITIONER

Petitioner's Power of Attorney for Concord Cheung

Feb 25, 2025PAPERPETITIONER

Petitioner’s Notice of Deposition of Julie L. Davis

Feb 10, 2025PAPERPETITIONER

Petitioner's Notice of Deposition of Hari Shroff, Ph.D.

Jan 28, 2025PAPERPETITIONER

EX2025 - Shroff CV

Dec 10, 2024EXHIBITPATENT OWNER

EX2027 - Davis CV

Dec 10, 2024EXHIBITPATENT OWNER

EX2028 - Bruker Completes Asset Acquisition

Dec 10, 2024EXHIBITPATENT OWNER

EX2029 - NanoString - About Us

Dec 10, 2024EXHIBITPATENT OWNER

EX2030 - NanoString - CosMx SMI Overview

Dec 10, 2024EXHIBITPATENT OWNER

EX2031 - Business Wire Nanostring Article

Dec 10, 2024EXHIBITPATENT OWNER

EX2032 - NanoString Form 10K (December 31 2022)

Dec 10, 2024EXHIBITPATENT OWNER

EX2033 - 10x Genomics - Company

Dec 10, 2024EXHIBITPATENT OWNER

EX2034 - 10x Form 10K (December 31 2023)

Dec 10, 2024EXHIBITPATENT OWNER

EX2035 - 10x Genomics Commercially Launches Xenium

Dec 10, 2024EXHIBITPATENT OWNER

EX2036 - 10x Genomics - Xenium In Situ Platform

Dec 10, 2024EXHIBITPATENT OWNER

EX2037 - 10x Genomics Begins Commercial Shipments

Dec 10, 2024EXHIBITPATENT OWNER

EX2038 - Nanostring First Fully Integrated Single-Cell Spatial Solution

Dec 10, 2024EXHIBITPATENT OWNER

EX2039 - NanoString - CosMx SMI Technology Access Program

Dec 10, 2024EXHIBITPATENT OWNER

EX2040 - JP Morgan Healthcare Presentation

Dec 10, 2024EXHIBITPATENT OWNER

EX2041 - Chen Dissertation

Dec 10, 2024EXHIBITPATENT OWNER

EX2042 - Uchida 2016

Dec 10, 2024EXHIBITPATENT OWNER

EX2043 - Czymmek Deposition Transcript

Dec 10, 2024EXHIBITPATENT OWNER

EX2044 - Zhang 2007

Dec 10, 2024EXHIBITPATENT OWNER

EX2045 - Waters 2009

Dec 10, 2024EXHIBITPATENT OWNER

EX2046 - Conchello 2005

Dec 10, 2024EXHIBITPATENT OWNER

EX2047 - Stallinga 2010

Dec 10, 2024EXHIBITPATENT OWNER

EX2048 - McCall 2015

Dec 10, 2024EXHIBITPATENT OWNER

EX2049 - Davis 2014

Dec 10, 2024EXHIBITPATENT OWNER

EX2050 - Lee 2014

Dec 10, 2024EXHIBITPATENT OWNER

EX2051 - Lubeck 2012

Dec 10, 2024EXHIBITPATENT OWNER

EX2052 - Lubeck 2014

Dec 10, 2024EXHIBITPATENT OWNER

EX2053 - Moffitt 2016

Dec 10, 2024EXHIBITPATENT OWNER

EX2024 - Shroff Declaration (PUBLIC - REDACTED)

Dec 10, 2024EXHIBITPATENT OWNER

EX2026 - Davis Declaration (PUBLIC - REDACTED)

Dec 10, 2024EXHIBITPATENT OWNER

EX2054 - App_17374000_ROA_1-26-2024

Dec 10, 2024EXHIBITPATENT OWNER

EX2055 - App_18184967_ROA_11-22-2023

Dec 10, 2024EXHIBITPATENT OWNER

EX2057 - Luo (US20120040397A1)

Dec 10, 2024EXHIBITPATENT OWNER

EX2058 - Green (US20140220587A1)

Dec 10, 2024EXHIBITPATENT OWNER

EX2059 - Chung 2013

Dec 10, 2024EXHIBITPATENT OWNER

EX2060 - Xenium User Guide

Dec 10, 2024EXHIBITPATENT OWNER

EX2061 - CosMx User Manual

Dec 10, 2024EXHIBITPATENT OWNER

EX2062 - CosMx Slide Manual

Dec 10, 2024EXHIBITPATENT OWNER

EX2064 - 10XH-00054907-10XH-00054996 (CONFIDENTIAL - PROTECTIVE ORDER MATERIAL)

Dec 10, 2024EXHIBITPATENT OWNER

EX2065 - CosMx Grant Package

Dec 10, 2024EXHIBITPATENT OWNER

EX2070 - 10X Genomics New Insights Into Cleft Palate

Dec 10, 2024EXHIBITPATENT OWNER

EX2071 - BioSpace 2023

Dec 10, 2024EXHIBITPATENT OWNER

EX2072 - Peroni 2024

Dec 10, 2024EXHIBITPATENT OWNER

EX2073 - 10X261-00003119-10X261-00003232 (CONFIDENTIAL - PROTECTIVE ORDER MATERIAL)

Dec 10, 2024EXHIBITPATENT OWNER

EX2074 - Small 2014

Dec 10, 2024EXHIBITPATENT OWNER

EX2075 - Huang 2011

Dec 10, 2024EXHIBITPATENT OWNER

EX2076 - Dobrucki 2007

Dec 10, 2024EXHIBITPATENT OWNER

EX2077 - Booth 2014

Dec 10, 2024EXHIBITPATENT OWNER

EX2078 - Diaspro 2020

Dec 10, 2024EXHIBITPATENT OWNER

EX2079 - Lee 2015

Dec 10, 2024EXHIBITPATENT OWNER

EX2080 - Schoder 2005

Dec 10, 2024EXHIBITPATENT OWNER

EX2081 - Ettinger 2014

Dec 10, 2024EXHIBITPATENT OWNER

EX2024 - Shroff Declaration (CONFIDENTIAL - PROTECTIVE ORDER MATERIAL)

Dec 10, 2024EXHIBITPATENT OWNER

EX2026 - Davis Declaration (CONFIDENTIAL - PROTECTIVE ORDER MATERIAL)

Dec 10, 2024EXHIBITPATENT OWNER

Patent Owner Response (PUBLIC - REDACTED)

Dec 10, 2024PAPERPATENT OWNER

Patent Owner Response (CONFIDENTIAL - PROTECTIVE ORDER MATERIAL)

Dec 10, 2024PAPERPATENT OWNER

Patent Owner's Motion to Seal

Dec 10, 2024PAPERPATENT OWNER

Patent Owner's Notice of Deposition

Nov 12, 2024PAPERPATENT OWNER

Notice of Joint Stipulation to Modify Due Dates 1-3

Oct 4, 2024PAPERPATENT OWNER

Patent Owner's Objections to Evidence

Sep 9, 2024PAPERPATENT OWNER

Granting Institution of Inter Partes Review 35 U.S.C. § 314

Aug 23, 2024PAPERBOARD

EXPUNGED

Aug 23, 2024PAPERBOARD

SCHEDULING ORDER

Aug 23, 2024PAPERBOARD

Order: Other - Granting NanoString Technologies, Inc.'s Unopposed Motion to Substitute Party - 37 CFR 42.5(a)

Jul 24, 2024PAPERBOARD

Exhibit 3002

Jul 16, 2024EXHIBITBOARD

Unopposed Motion to Substitute Party

Jul 16, 2024PAPERPETITIONER

Patent Owner’s Updated Mandatory Notice

Jul 16, 2024PAPERPETITIONER

EX2013 - Docket Report 2024-07-08

Jul 8, 2024EXHIBITPATENT OWNER

EX2014 - Oral Order 2023-04-25

Jul 8, 2024EXHIBITPATENT OWNER

EX2015 - Hearing Transcript 2024-06-14

Jul 8, 2024EXHIBITPATENT OWNER

EX2016 - Notice of Service 2022-11-23

Jul 8, 2024EXHIBITPATENT OWNER

EX2017 - Notice of Service 2023-01-03

Jul 8, 2024EXHIBITPATENT OWNER

EX2018 - Notice of Service 2023-03-24

Jul 8, 2024EXHIBITPATENT OWNER

EX2019 - Notice of Service 2023-05-17

Jul 8, 2024EXHIBITPATENT OWNER

EX2020 - Memorandum Opinion and Order 2024-02-01

Jul 8, 2024EXHIBITPATENT OWNER

EX2021 - Notice of Service 2022-11-23

Jul 8, 2024EXHIBITPATENT OWNER

EX2022 - Notice of Service 2022-12-27

Jul 8, 2024EXHIBITPATENT OWNER

EX2023 - E-mail

Jul 8, 2024EXHIBITPATENT OWNER

Pre-Institution Sur-Reply

Jul 8, 2024PAPERPATENT OWNER

Petitioner’s Reply to Patent Owner’s Preliminary Response

Jul 1, 2024PAPERPETITIONER

EX1066

Jul 1, 2024EXHIBITPETITIONER

EX1067

Jul 1, 2024EXHIBITPETITIONER

EX1068

Jul 1, 2024EXHIBITPETITIONER

EX1069

Jul 1, 2024EXHIBITPETITIONER

EX1070

Jul 1, 2024EXHIBITPETITIONER

EX1071

Jul 1, 2024EXHIBITPETITIONER

EX1072

Jul 1, 2024EXHIBITPETITIONER

Exhibit 3001

Jun 24, 2024EXHIBITBOARD

EX2001 - Stahl 2016 with Supplemental Data

May 28, 2024EXHIBITPATENT OWNER

EX2002 - Waller Declaration

May 28, 2024EXHIBITPATENT OWNER

EX2003 - WO2012140224A1 (Frisen)

May 28, 2024EXHIBITPATENT OWNER

EX2007 - Zhuang 2023

May 28, 2024EXHIBITPATENT OWNER

EX2008 - Lu 2022

May 28, 2024EXHIBITPATENT OWNER

EX2009 - Su 2020

May 28, 2024EXHIBITPATENT OWNER

EX2010 - Czymmek 2022

May 28, 2024EXHIBITPATENT OWNER

EX2011 - Ghani 2019

May 28, 2024EXHIBITPATENT OWNER

EX2012 - Waller CV

May 28, 2024EXHIBITPATENT OWNER

Patent Owner Preliminary Response

May 28, 2024PAPERPATENT OWNER

EX2006 - 554 Patent File History (Part 1 of 2)

May 28, 2024EXHIBITPATENT OWNER

EX2006 - 554 Patent File History (Part 2 of 2)

May 28, 2024EXHIBITPATENT OWNER

EX2004 - FCS2 - No-Heat Flow Cell (FCS2) – Bioptechs

May 28, 2024EXHIBITPATENT OWNER

EX2005 - FCS2 Chamber – Bioptechs

May 28, 2024EXHIBITPATENT OWNER

Notice: Notice filing date accorded

Feb 26, 2024PAPERBOARD

Patent Owner President and Fellows of Harvard College's Power of Attorney

Feb 21, 2024PAPERPATENT OWNER

Patent Owner President and Fellows of Harvard College's Mandatory Notices

Feb 21, 2024PAPERPATENT OWNER

Exclusive Licensee's Power of Attorney

Feb 20, 2024PAPERPATENT OWNER

Exclusive Licensee's Mandatory Notices

Feb 20, 2024PAPERPATENT OWNER

Petitioner's Power of Attorney

Jan 30, 2024PAPERPETITIONER

Petition For Inter Partes Review of U.S. Patent No. 11,542,554

Jan 30, 2024PAPERPETITIONER

U.S. Patent No. 11,542,554

Jan 30, 2024EXHIBITPETITIONER

Declaration of Kirk Cyzmmek

Jan 30, 2024EXHIBITPETITIONER

Zhuang

Jan 30, 2024EXHIBITPETITIONER

U.S. Patent No. 10,457,980

Jan 30, 2024EXHIBITPETITIONER

Olympus IX71/IX51 Manual

Jan 30, 2024EXHIBITPETITIONER

FCS2 Instructions

Jan 30, 2024EXHIBITPETITIONER

Sivaramakrishnan - Molecular Biology of the Cell

Jan 30, 2024EXHIBITPETITIONER

Larsson - In Situ Detection and Genotyping of Individual mRNA Molecules

Jan 30, 2024EXHIBITPETITIONER

Querido - Using Fluorescent Proteins to Study mRNA Trafficking Living Cell

Jan 30, 2024EXHIBITPETITIONER

Femino - Visualization of Single Molecules of mRNA in Situ

Jan 30, 2024EXHIBITPETITIONER

Perillo - Enhanced 3D Localization of Individual RNA transcripts

Jan 30, 2024EXHIBITPETITIONER

North

Jan 30, 2024EXHIBITPETITIONER

U.S. Patent Application No. 2015/0267251 A1

Jan 30, 2024EXHIBITPETITIONER

James - Water Objectives (2006)

Jan 30, 2024EXHIBITPETITIONER

Spector - Volume 2: Light Microscopy and Cell Structure

Jan 30, 2024EXHIBITPETITIONER

Hamilton Website

Jan 30, 2024EXHIBITPETITIONER

O'Connor - Fluorescence in Situ Hybridization

Jan 30, 2024EXHIBITPETITIONER

Toomre

Jan 30, 2024EXHIBITPETITIONER

Fischer - Microscopy in 3D: A Biologist's Toolbox

Jan 30, 2024EXHIBITPETITIONER

Shah

Jan 30, 2024EXHIBITPETITIONER

Moffitt - RNA Imaging with Multiplexed Error Robust Fluorescence in Situ

Jan 30, 2024EXHIBITPETITIONER

Chirieleison - Automated Cell Imaging Systems Reveal Dynamic Cell Behavior

Jan 30, 2024EXHIBITPETITIONER

Image Processing with ImageJ

Jan 30, 2024EXHIBITPETITIONER

Hodneland - CellSegm Article

Jan 30, 2024EXHIBITPETITIONER

Delaune

Jan 30, 2024EXHIBITPETITIONER

Bui - Analytical Devices Based on Light-Emitting Diodes

Jan 30, 2024EXHIBITPETITIONER

Xiao - Handbook of Single-Molecule Biophysics

Jan 30, 2024EXHIBITPETITIONER

Ehrlicher - Optical Neuronal Guidance

Jan 30, 2024EXHIBITPETITIONER

Fang-Yen - Video-Rate Tomographic Phase Microscopy

Jan 30, 2024EXHIBITPETITIONER

Richard

Jan 30, 2024EXHIBITPETITIONER

Syringe Pumps Manual

Jan 30, 2024EXHIBITPETITIONER

Shen - Digital Autofocus Methods for Automated Microscopy

Jan 30, 2024EXHIBITPETITIONER

Olympus IX71/IX81 Brochure

Jan 30, 2024EXHIBITPETITIONER

'554 Patent File History (Disclosure Statement by Applicant)

Jan 30, 2024EXHIBITPETITIONER

'554 Patent File History (Office Action Summary)

Jan 30, 2024EXHIBITPETITIONER

'554 Patent File History (Notice of Allowance and Fees Due)

Jan 30, 2024EXHIBITPETITIONER

'554 Patent File History (Pending Claims)

Jan 30, 2024EXHIBITPETITIONER

'554 File History (Remarks)

Jan 30, 2024EXHIBITPETITIONER

Brileya

Jan 30, 2024EXHIBITPETITIONER

Brooker - U.S. Patent Application No. 2011/0090562 A1

Jan 30, 2024EXHIBITPETITIONER

Callahan - U.S. Application Patent No. 2011/0216953

Jan 30, 2024EXHIBITPETITIONER

Keller - U.S. Patent Application No. 2015/0098126 A1

Jan 30, 2024EXHIBITPETITIONER

Nikon

Jan 30, 2024EXHIBITPETITIONER

Niman

Jan 30, 2024EXHIBITPETITIONER

Cy5 Beads Emission Spectra

Jan 30, 2024EXHIBITPETITIONER

Sands

Jan 30, 2024EXHIBITPETITIONER

Schneider - NIH Image to ImageJ: 25 Years of Image Analysis

Jan 30, 2024EXHIBITPETITIONER

Skafte

Jan 30, 2024EXHIBITPETITIONER

Tirichine

Jan 30, 2024EXHIBITPETITIONER

Wessels - Light Emitting Diodes in Modern Microscopy

Jan 30, 2024EXHIBITPETITIONER

Winer - Application of a Three-Dimensional Particle Tracking Method

Jan 30, 2024EXHIBITPETITIONER

Zessin

Jan 30, 2024EXHIBITPETITIONER

Olympus IX2 Series Brochure

Jan 30, 2024EXHIBITPETITIONER

Gerhardt - Detection of Singles Molecules

Jan 30, 2024EXHIBITPETITIONER

Hattori - Single Molecule Imaging with an Inexpensive UV-LED Light Source

Jan 30, 2024EXHIBITPETITIONER

Kuo - High-power Blue/UV Light-Emitting Diodes as Excitation Sources

Jan 30, 2024EXHIBITPETITIONER

F8809 FluoSpheres Webpage

Jan 30, 2024EXHIBITPETITIONER

EX1005 MetaData

Jan 30, 2024EXHIBITPETITIONER

EX1033 MetaData

Jan 30, 2024EXHIBITPETITIONER

EX1053 MetaData

Jan 30, 2024EXHIBITPETITIONER

Stipulation & Order Amending Scheduling Order (C.A. No. 22-261-MFK)

Jan 30, 2024EXHIBITPETITIONER

Plaintiff's Complaint (22-00261-MFK)

Jan 30, 2024EXHIBITPETITIONER

Plaintiff's Second Amended Complaint (22-00261-MFK)

Jan 30, 2024EXHIBITPETITIONER

NanoString's First Amended Answer to Complaint (22-00261-MFK)

Jan 30, 2024EXHIBITPETITIONER

Kirk Czymmek CV

Jan 30, 2024EXHIBITPETITIONER