The detailed information for PTAB case with proceeding number IPR2024-00623 filed by Merck Sharp & Dohme LLC et al. against The Johns Hopkins University on Mar 4, 2024. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.

Case Details

Proceeding Number
IPR2024-00623
Filing Date
Mar 4, 2024
Petitioner
Merck Sharp & Dohme LLC et al.
Respondent
The Johns Hopkins University
Status
Trial Instituted
Respondent Application Number
17131326
Respondent Tech Center
1600
Respondent Patent Number
11325974
Institution Decision Date
Sep 23, 2024

Proceeding Documents

The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.


Document NameFiling DateCategoryFiling Party

Alert me when new update on this case

Order Conduct of the Proceeding

Jun 18, 2025PAPERBOARD

Ex. 3009 Attorney Correspondence

Jun 16, 2025EXHIBITBOARD

Order: Canceling Oral Argument

Jun 16, 2025PAPERBOARD

Public_Patent Owners Sur-Reply

Jun 12, 2025PAPERPATENT OWNER

Public_Deposition Transcript of Paul E. Oberstein

Jun 12, 2025EXHIBITPATENT OWNER

Public_Deposition Transcript of Sean D. Sheridan

Jun 12, 2025EXHIBITPATENT OWNER

ORDER Setting Oral Argument 37 C.F.R. § 42.70

Jun 3, 2025PAPERBOARD

Confidential_Patent Owners Sur-Reply

May 29, 2025PAPERPATENT OWNER

Confidential_Deposition Transcript of Paul E. Oberstein

May 29, 2025EXHIBITPATENT OWNER

Confidential_Deposition Transcript of Sean D. Sheridan

May 29, 2025EXHIBITPATENT OWNER

Patent Owner's Motion to Seal Sur-Reply and Exhibits

May 29, 2025PAPERPATENT OWNER

Petitioner's Reply [Redacted]

May 15, 2025PAPERPETITIONER

Exhibit 1137 [Redacted]

May 15, 2025EXHIBITPETITIONER

Exhibit 1150 [Redacted]

May 15, 2025EXHIBITPETITIONER

Exhibit 1151 [Redacted]

May 15, 2025EXHIBITPETITIONER

Exhibit 1244 [Redacted]

May 15, 2025EXHIBITPETITIONER

Exhibit 1245 [Redacted]

May 15, 2025EXHIBITPETITIONER

Exhibit 1269 [Redacted]

May 15, 2025EXHIBITPETITIONER

Exhibit 1270 [Redacted]

May 15, 2025EXHIBITPETITIONER

Patent Owner's Request for Oral Argument

May 12, 2025PAPERPATENT OWNER

Petitioner's Request for Oral Argument

May 12, 2025PAPERPETITIONER

Petitioner's Current List of Exhibits

May 1, 2025PAPERPETITIONER

Exhibit 1113

May 1, 2025EXHIBITPETITIONER

Exhibit 1114

May 1, 2025EXHIBITPETITIONER

Exhibit 1115

May 1, 2025EXHIBITPETITIONER

Exhibit 1117

May 1, 2025EXHIBITPETITIONER

Exhibit 1120

May 1, 2025EXHIBITPETITIONER

Exhibit 1122

May 1, 2025EXHIBITPETITIONER

Exhibit 1128

May 1, 2025EXHIBITPETITIONER

Exhibit 1129

May 1, 2025EXHIBITPETITIONER

Exhibit 1130

May 1, 2025EXHIBITPETITIONER

Exhibit 1134

May 1, 2025EXHIBITPETITIONER

Exhibit 1135

May 1, 2025EXHIBITPETITIONER

Exhibit 1136

May 1, 2025EXHIBITPETITIONER

Exhibit 1137 [REDACTED]

May 1, 2025EXHIBITPETITIONER

Exhibit 1138

May 1, 2025EXHIBITPETITIONER

Exhibit 1139

May 1, 2025EXHIBITPETITIONER

Exhibit 1140

May 1, 2025EXHIBITPETITIONER

Exhibit 1141

May 1, 2025EXHIBITPETITIONER

Exhibit 1145

May 1, 2025EXHIBITPETITIONER

Exhibit 1146

May 1, 2025EXHIBITPETITIONER

Exhibit 1147

May 1, 2025EXHIBITPETITIONER

Exhibit 1148

May 1, 2025EXHIBITPETITIONER

Exhibit 1149

May 1, 2025EXHIBITPETITIONER

Exhibit 1152

May 1, 2025EXHIBITPETITIONER

Exhibit 1153

May 1, 2025EXHIBITPETITIONER

Exhibit 1154

May 1, 2025EXHIBITPETITIONER

Exhibit 1155

May 1, 2025EXHIBITPETITIONER

Exhibit 1156

May 1, 2025EXHIBITPETITIONER

Exhibit 1158

May 1, 2025EXHIBITPETITIONER

Exhibit 1159

May 1, 2025EXHIBITPETITIONER

Exhibit 1160

May 1, 2025EXHIBITPETITIONER

Exhibit 1161

May 1, 2025EXHIBITPETITIONER

Exhibit 1162

May 1, 2025EXHIBITPETITIONER

Exhibit 1163

May 1, 2025EXHIBITPETITIONER

Exhibit 1164

May 1, 2025EXHIBITPETITIONER

Exhibit 1165

May 1, 2025EXHIBITPETITIONER

Exhibit 1166

May 1, 2025EXHIBITPETITIONER

Exhibit 1167

May 1, 2025EXHIBITPETITIONER

Exhibit 1168

May 1, 2025EXHIBITPETITIONER

Exhibit 1169

May 1, 2025EXHIBITPETITIONER

Exhibit 1170

May 1, 2025EXHIBITPETITIONER

Exhibit 1171

May 1, 2025EXHIBITPETITIONER

Exhibit 1172

May 1, 2025EXHIBITPETITIONER

Exhibit 1173

May 1, 2025EXHIBITPETITIONER

Exhibit 1174

May 1, 2025EXHIBITPETITIONER

Exhibit 1175

May 1, 2025EXHIBITPETITIONER

Exhibit 1176

May 1, 2025EXHIBITPETITIONER

Exhibit 1177

May 1, 2025EXHIBITPETITIONER

Exhibit 1178

May 1, 2025EXHIBITPETITIONER

Exhibit 1179

May 1, 2025EXHIBITPETITIONER

Exhibit 1180

May 1, 2025EXHIBITPETITIONER

Exhibit 1181

May 1, 2025EXHIBITPETITIONER

Exhibit 1182

May 1, 2025EXHIBITPETITIONER

Exhibit 1183

May 1, 2025EXHIBITPETITIONER

Exhibit 1184

May 1, 2025EXHIBITPETITIONER

Exhibit 1185

May 1, 2025EXHIBITPETITIONER

Exhibit 1186

May 1, 2025EXHIBITPETITIONER

Exhibit 1187

May 1, 2025EXHIBITPETITIONER

Exhibit 1188

May 1, 2025EXHIBITPETITIONER

Exhibit 1189

May 1, 2025EXHIBITPETITIONER

Exhibit 1190

May 1, 2025EXHIBITPETITIONER

Exhibit 1191

May 1, 2025EXHIBITPETITIONER

Exhibit 1192

May 1, 2025EXHIBITPETITIONER

Exhibit 1193

May 1, 2025EXHIBITPETITIONER

Exhibit 1194

May 1, 2025EXHIBITPETITIONER

Exhibit 1195

May 1, 2025EXHIBITPETITIONER

Exhibit 1196

May 1, 2025EXHIBITPETITIONER

Exhibit 1197

May 1, 2025EXHIBITPETITIONER

Exhibit 1198

May 1, 2025EXHIBITPETITIONER

Exhibit 1199

May 1, 2025EXHIBITPETITIONER

Exhibit 1200

May 1, 2025EXHIBITPETITIONER

Exhibit 1201

May 1, 2025EXHIBITPETITIONER

Exhibit 1202

May 1, 2025EXHIBITPETITIONER

Exhibit 1203

May 1, 2025EXHIBITPETITIONER

Exhibit 1204

May 1, 2025EXHIBITPETITIONER

Exhibit 1205

May 1, 2025EXHIBITPETITIONER

Exhibit 1206

May 1, 2025EXHIBITPETITIONER

Exhibit 1207

May 1, 2025EXHIBITPETITIONER

Exhibit 1208

May 1, 2025EXHIBITPETITIONER

Exhibit 1209

May 1, 2025EXHIBITPETITIONER

Exhibit 1210

May 1, 2025EXHIBITPETITIONER

Exhibit 1213

May 1, 2025EXHIBITPETITIONER

Exhibit 1214

May 1, 2025EXHIBITPETITIONER

Exhibit 1215

May 1, 2025EXHIBITPETITIONER

Exhibit 1217

May 1, 2025EXHIBITPETITIONER

Exhibit 1218

May 1, 2025EXHIBITPETITIONER

Exhibit 1219

May 1, 2025EXHIBITPETITIONER

Exhibit 1220

May 1, 2025EXHIBITPETITIONER

Exhibit 1221

May 1, 2025EXHIBITPETITIONER

Exhibit 1222

May 1, 2025EXHIBITPETITIONER

Exhibit 1223

May 1, 2025EXHIBITPETITIONER

Exhibit 1224

May 1, 2025EXHIBITPETITIONER

Exhibit 1225

May 1, 2025EXHIBITPETITIONER

Exhibit 1238

May 1, 2025EXHIBITPETITIONER

Exhibit 1242

May 1, 2025EXHIBITPETITIONER

Exhibit 1243

May 1, 2025EXHIBITPETITIONER

Exhibit 1246

May 1, 2025EXHIBITPETITIONER

Exhibit 1249

May 1, 2025EXHIBITPETITIONER

Exhibit 1250

May 1, 2025EXHIBITPETITIONER

Exhibit 1251

May 1, 2025EXHIBITPETITIONER

Exhibit 1252

May 1, 2025EXHIBITPETITIONER

Exhibit 1253

May 1, 2025EXHIBITPETITIONER

Exhibit 1254

May 1, 2025EXHIBITPETITIONER

Exhibit 1255

May 1, 2025EXHIBITPETITIONER

Exhibit 1256

May 1, 2025EXHIBITPETITIONER

Exhibit 1257

May 1, 2025EXHIBITPETITIONER

Exhibit 1258

May 1, 2025EXHIBITPETITIONER

Exhibit 1259

May 1, 2025EXHIBITPETITIONER

Exhibit 1260

May 1, 2025EXHIBITPETITIONER

Exhibit 1261

May 1, 2025EXHIBITPETITIONER

Exhibit 1262

May 1, 2025EXHIBITPETITIONER

Exhibit 1263

May 1, 2025EXHIBITPETITIONER

Exhibit 1264

May 1, 2025EXHIBITPETITIONER

Exhibit 1265

May 1, 2025EXHIBITPETITIONER

Exhibit 1266

May 1, 2025EXHIBITPETITIONER

Exhibit 1267

May 1, 2025EXHIBITPETITIONER

Exhibit 1268

May 1, 2025EXHIBITPETITIONER

Exhibit 1273

May 1, 2025EXHIBITPETITIONER

Exhibit 1275

May 1, 2025EXHIBITPETITIONER

Exhibit 1276

May 1, 2025EXHIBITPETITIONER

Exhibit 1277

May 1, 2025EXHIBITPETITIONER

Exhibit 1278

May 1, 2025EXHIBITPETITIONER

Exhibit 1279

May 1, 2025EXHIBITPETITIONER

Exhibit 1280

May 1, 2025EXHIBITPETITIONER

Exhibit 1281

May 1, 2025EXHIBITPETITIONER

Petitioner's Motion to Seal

May 1, 2025PAPERPETITIONER

Exhibit 1116 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1118 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1119 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1137 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1150 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1151 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1157 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1244 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1245 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1269 [Confidential]

May 1, 2025EXHIBITPETITIONER

Exhibit 1270 [Confidential]

May 1, 2025EXHIBITPETITIONER

Petitioner's Reply [Confidential]

May 1, 2025PAPERPETITIONER

Notice of Stipulation to Modify Due Dates

Apr 10, 2025PAPERPETITIONER

Petitioner's Notice of Deposition of Dung Le M.D

Apr 10, 2025PAPERPETITIONER

Petitioner's Notice of Deposition of Nils Lonberg, Ph.D.

Apr 10, 2025PAPERPETITIONER

Petitioner's Notice of Deposition of Jennifer Newberger

Apr 8, 2025PAPERPETITIONER

Petitioner's Notice of Deposition of Richard Goldberg, M.D.

Apr 8, 2025PAPERPETITIONER

Petitioner's Notice of Deposition of Brian J. Segers

Apr 8, 2025PAPERPETITIONER

Petitioner's Corrected Notice of Deposition of Brian J. Segers

Apr 8, 2025PAPERPETITIONER

Patent Owners Updated Mandatory Notice

Mar 28, 2025PAPERPATENT OWNER

Patent Owners Updated Power of Attorney

Mar 28, 2025PAPERPATENT OWNER

ORDER Conditionally Granting Patent Owner’s Motions for Pro Hac Vice Admission of Caroline (Gracie) Koonce. 37 C.F.R. § 42.10

Mar 26, 2025PAPERBOARD

Patent Owner's Unopposed Motion for PHV Admission of Caroline Koonce

Mar 18, 2025PAPERPATENT OWNER

PHV Declaration - Caroline Koonce

Mar 18, 2025EXHIBITPATENT OWNER

Patent Owners Updated Mandatory Notice

Jan 29, 2025PAPERPATENT OWNER

Public_Patent Owners Response

Jan 28, 2025PAPERPATENT OWNER

Public_Declaration of Brian Segers

Jan 28, 2025EXHIBITPATENT OWNER

Petitioner's Objections to Patent Owner's Exhibits

Jan 21, 2025PAPERPETITIONER

Confidential - Protective Order Material

Jan 15, 2025EXHIBITPATENT OWNER

Confidential - Protective Order Material

Jan 15, 2025EXHIBITPATENT OWNER

Confidential - Protective Order Material

Jan 15, 2025EXHIBITPATENT OWNER

Curriculum Vitae of Dr. Nils Lonberg

Jan 13, 2025EXHIBITPATENT OWNER

News Release_Keytruda

Jan 13, 2025EXHIBITPATENT OWNER

Bacher_Development of a Fluorescent Multiplex Assay

Jan 13, 2025EXHIBITPATENT OWNER

Diaz_Liquid Biopsies

Jan 13, 2025EXHIBITPATENT OWNER

Brahmer_Phase I Study

Jan 13, 2025EXHIBITPATENT OWNER

The Cancer Genome Atlas Network

Jan 13, 2025EXHIBITPATENT OWNER

Mandrekar_All-Comers versus Enrichment Design

Jan 13, 2025EXHIBITPATENT OWNER

Freidlin_Randomized Clinical Trials

Jan 13, 2025EXHIBITPATENT OWNER

Malik_Consensus Report

Jan 13, 2025EXHIBITPATENT OWNER

NIH_What is Cancer

Jan 13, 2025EXHIBITPATENT OWNER

Weiss_Open Questions

Jan 13, 2025EXHIBITPATENT OWNER

Mumphrey_Distinct Mutational Processes

Jan 13, 2025EXHIBITPATENT OWNER

Jenkins_Antigen Presentation

Jan 13, 2025EXHIBITPATENT OWNER

Wherry_Viral Persistence

Jan 13, 2025EXHIBITPATENT OWNER

Lotze_Lysis of Fresh and Cultured Autologous Tumor

Jan 13, 2025EXHIBITPATENT OWNER

Briukhovetska_Interleukins in Cancer

Jan 13, 2025EXHIBITPATENT OWNER

Bod_B-Cell-Specific Checkpoint

Jan 13, 2025EXHIBITPATENT OWNER

Wang_CD19

Jan 13, 2025EXHIBITPATENT OWNER

Michaud_Regulatory B Cells in Cancer

Jan 13, 2025EXHIBITPATENT OWNER

Nakhoda_Addressing Recent Failures

Jan 13, 2025EXHIBITPATENT OWNER

Korman_The Foundations

Jan 13, 2025EXHIBITPATENT OWNER

NIH_Immune Checkpoint Inhibitors

Jan 13, 2025EXHIBITPATENT OWNER

Boland_Microsatellite Instability

Jan 13, 2025EXHIBITPATENT OWNER

Branch_Immune Surveillance

Jan 13, 2025EXHIBITPATENT OWNER

Kloor_Immune Evasion

Jan 13, 2025EXHIBITPATENT OWNER

Zhong_Comparison of Molecular and Cellular Phenotypes

Jan 13, 2025EXHIBITPATENT OWNER

Thomas_Advancing Translational Research

Jan 13, 2025EXHIBITPATENT OWNER

Lacombe_The Dream and Reality

Jan 13, 2025EXHIBITPATENT OWNER

FDA Approves Mercks KEYTRUDA (pembrolizumab)

Jan 13, 2025EXHIBITPATENT OWNER

irst-Study-Evaluating-DNA-Mismatch-Repair

Jan 13, 2025EXHIBITPATENT OWNER

Merck-Receives-Breakthrough-Therapy

Jan 13, 2025EXHIBITPATENT OWNER

MRK-USQ_Transcript_2019-02-01-Final

Jan 13, 2025EXHIBITPATENT OWNER

Merck_Financial-Results-2023

Jan 13, 2025EXHIBITPATENT OWNER

Merck_Financial-Results-2022

Jan 13, 2025EXHIBITPATENT OWNER

Merck_Financial-Results-2021

Jan 13, 2025EXHIBITPATENT OWNER

Merck_Financial-Results-2020

Jan 13, 2025EXHIBITPATENT OWNER

Merck_Financial-Results-2019

Jan 13, 2025EXHIBITPATENT OWNER

Exhibit 14 to JHU Corrected Answer and Counterclaims

Jan 13, 2025EXHIBITPATENT OWNER

statistic_id973523_top-drugs-based-on-projected-2024-global-sales

Jan 13, 2025EXHIBITPATENT OWNER

1-22-cv-03059-100, Ltr fr JHU to Judge Aslan

Jan 13, 2025EXHIBITPATENT OWNER

Declaration of Dr. Nils Lonberg

Jan 13, 2025EXHIBITPATENT OWNER

Connolly_Novel Mouse Models

Jan 13, 2025EXHIBITPATENT OWNER

Sun_Immune checkpoint therapy

Jan 13, 2025EXHIBITPATENT OWNER

Dobosz_Challenges of the Immunotherapy

Jan 13, 2025EXHIBITPATENT OWNER

Gardner_Merck suffers bad week

Jan 13, 2025EXHIBITPATENT OWNER

Liu_Merck's Keytruda flunks pivotal studies

Jan 13, 2025EXHIBITPATENT OWNER

Hopkins_Merck Keeps Striking Out

Jan 13, 2025EXHIBITPATENT OWNER

Merck's trial of Keytruda

Jan 13, 2025EXHIBITPATENT OWNER

Study of Pembrolizumab

Jan 13, 2025EXHIBITPATENT OWNER

van der Bruggen_A gene encoding an antigen

Jan 13, 2025EXHIBITPATENT OWNER

Lawrence_Mutational heterogeneity

Jan 13, 2025EXHIBITPATENT OWNER

Kitano_Myeloid-derived suppressor

Jan 13, 2025EXHIBITPATENT OWNER

Snyder_Genetic basis for clinical response

Jan 13, 2025EXHIBITPATENT OWNER

Chan_Genetic Basis for Clinical Response

Jan 13, 2025EXHIBITPATENT OWNER

McGranahan_Clonal neoantigens

Jan 13, 2025EXHIBITPATENT OWNER

Hellmann_Tumor Mutational

Jan 13, 2025EXHIBITPATENT OWNER

FDA grants nivolumab accelerated approval

Jan 13, 2025EXHIBITPATENT OWNER

Boyiadzis_Significance and implications

Jan 13, 2025EXHIBITPATENT OWNER

Declaration of Dr. Richard Goldberg

Jan 13, 2025EXHIBITPATENT OWNER

Bray_Global cancer statistics

Jan 13, 2025EXHIBITPATENT OWNER

Zeineddine_Survival improvement

Jan 13, 2025EXHIBITPATENT OWNER

Patel_The rising tide

Jan 13, 2025EXHIBITPATENT OWNER

Sinicrope_Increasing Incidence

Jan 13, 2025EXHIBITPATENT OWNER

Sinicrope_Lynch Syndrome

Jan 13, 2025EXHIBITPATENT OWNER

Sargent_Defective mismatch repair

Jan 13, 2025EXHIBITPATENT OWNER

Keung_The eighth edition American Joint Committee

Jan 13, 2025EXHIBITPATENT OWNER

Ogunwobi_Biomarkers in Colorectal Cancer

Jan 13, 2025EXHIBITPATENT OWNER

Kong_Prolonged surveillance

Jan 13, 2025EXHIBITPATENT OWNER

Modulation of fluorouracil

Jan 13, 2025EXHIBITPATENT OWNER

Dy_Long-term survivors

Jan 13, 2025EXHIBITPATENT OWNER

Saltz_Irinotecan plus fluorouracil

Jan 13, 2025EXHIBITPATENT OWNER

Sanoff_Five-year data

Jan 13, 2025EXHIBITPATENT OWNER

Hurwitz_Bevacizumab plus irinotecan

Jan 13, 2025EXHIBITPATENT OWNER

Saltz_Phase II trial

Jan 13, 2025EXHIBITPATENT OWNER

Van Cutsem_Cetuximab and chemotherapy

Jan 13, 2025EXHIBITPATENT OWNER

Van Cutsem_Open-label phase III trial

Jan 13, 2025EXHIBITPATENT OWNER

Tabernero_Aflibercept versus placebo

Jan 13, 2025EXHIBITPATENT OWNER

McRee_Optimal management

Jan 13, 2025EXHIBITPATENT OWNER

Lucas_A decade of advances

Jan 13, 2025EXHIBITPATENT OWNER

Modest_Treatment sequencing

Jan 13, 2025EXHIBITPATENT OWNER

Grothey_Regorafenib monotherapy

Jan 13, 2025EXHIBITPATENT OWNER

Mayer_Randomized trial of TAS-102

Jan 13, 2025EXHIBITPATENT OWNER

Topalian_Immune checkpoint blockade

Jan 13, 2025EXHIBITPATENT OWNER

Robert_Pembrolizumab versus Ipilimumab

Jan 13, 2025EXHIBITPATENT OWNER

Reck_Pembrolizumab versus Chemotherapy

Jan 13, 2025EXHIBITPATENT OWNER

Le_Mismatch repair deficiency

Jan 13, 2025EXHIBITPATENT OWNER

Ethical Guidelines

Jan 13, 2025EXHIBITPATENT OWNER

The Belmont Report

Jan 13, 2025EXHIBITPATENT OWNER

The Cancer Letter, Vol. 43, No. 38, Oct. 13, 2017

Jan 13, 2025EXHIBITPATENT OWNER

The Cancer Letter, Vol. 48, No. 23, June 10, 2022

Jan 13, 2025EXHIBITPATENT OWNER

How Beth Carner went from six weeks

Jan 13, 2025EXHIBITPATENT OWNER

Merck KEYTRUDA May 23, 2017

Jan 13, 2025EXHIBITPATENT OWNER

Merck KEYTRUDA Oct. 2015

Jan 13, 2025EXHIBITPATENT OWNER

Merck KEYTRUDA Aug. 2016

Jan 13, 2025EXHIBITPATENT OWNER

Merck KEYTRUDA Mar. 2017

Jan 13, 2025EXHIBITPATENT OWNER

Merck KEYTRUDA May 18, 2017

Jan 13, 2025EXHIBITPATENT OWNER

Merck KEYTRUDA June 2020

Jan 13, 2025EXHIBITPATENT OWNER

Declaration of Dung Le, M.D.

Jan 13, 2025EXHIBITPATENT OWNER

Investigator Initiated Clinical Trial Research

Jan 13, 2025EXHIBITPATENT OWNER

O'Neil_Safety and antitumor activity

Jan 13, 2025EXHIBITPATENT OWNER

FDA Grants Priority Review

Jan 13, 2025EXHIBITPATENT OWNER

Merck Makes 3 Million Charitable Donation

Jan 13, 2025EXHIBITPATENT OWNER

ASCO 2015_Mismatch Repair Deficiency

Jan 13, 2025EXHIBITPATENT OWNER

Video interview

Jan 13, 2025EXHIBITPATENT OWNER

Declaration of Ms. Jennifer Newberger

Jan 13, 2025EXHIBITPATENT OWNER

Dickersin_Report from the panel

Jan 13, 2025EXHIBITPATENT OWNER

Moher_Clinical-trial registration

Jan 13, 2025EXHIBITPATENT OWNER

International Clinical Trials

Jan 13, 2025EXHIBITPATENT OWNER

The Food and Drug Administration Modernization Act

Jan 13, 2025EXHIBITPATENT OWNER

Laine_Update on Trials Registration

Jan 13, 2025EXHIBITPATENT OWNER

Food and Drug Administration Amendments Act

Jan 13, 2025EXHIBITPATENT OWNER

About ClinicalTrials.gov_Nat'l Library of Medicine

Jan 13, 2025EXHIBITPATENT OWNER

7th Revision of the Declaration of Helsinki

Jan 13, 2025EXHIBITPATENT OWNER

42 C.F.R. Pt. 11_2024

Jan 13, 2025EXHIBITPATENT OWNER

42 USC 282(j) Paragraph 21

Jan 13, 2025EXHIBITPATENT OWNER

Protocol Registration Data

Jan 13, 2025EXHIBITPATENT OWNER

21 U.S.C. 331 - Prohibited acts

Jan 13, 2025EXHIBITPATENT OWNER

21 U.S.C. 333 - Penalties

Jan 13, 2025EXHIBITPATENT OWNER

De Angelis_Clinical trial registration

Jan 13, 2025EXHIBITPATENT OWNER

Stenographic Deposition of Alfred I. Neugut, M.D., Ph.D.

Jan 13, 2025EXHIBITPATENT OWNER

EX1096 from '187 proceeding_IPR2024-00649

Jan 13, 2025EXHIBITPATENT OWNER

Record History Tab

Jan 13, 2025EXHIBITPATENT OWNER

Comparison_ClinicalTrials.gov

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 1

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 2

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 4

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 5

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 6

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 7

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 8

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 9

Jan 13, 2025EXHIBITPATENT OWNER

André_KEYNOTE-177 Investigators

Jan 13, 2025EXHIBITPATENT OWNER

Henig_Could Immunotherapy Lead the Way

Jan 13, 2025EXHIBITPATENT OWNER

Exhibit 2 KEYTRUDA claim chart

Jan 13, 2025EXHIBITPATENT OWNER

Marques_Tumor mutational burden

Jan 13, 2025EXHIBITPATENT OWNER

Le_Phase II Open-label study

Jan 13, 2025EXHIBITPATENT OWNER

Nair_High Impact Journals 2024

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 3

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 10

Jan 13, 2025EXHIBITPATENT OWNER

Email correspondence from Luis Diaz

Jan 13, 2025EXHIBITPATENT OWNER

Breakthroughs in Immunotherapy

Jan 13, 2025EXHIBITPATENT OWNER

Guidance for Industry

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 11

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Document 12

Jan 13, 2025EXHIBITPATENT OWNER

Email correspondence from Preston K. Ratliff

Jan 13, 2025EXHIBITPATENT OWNER

How Does KEYTRUDA Work

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 27, 2015

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 26, 2024

Jan 13, 2025EXHIBITPATENT OWNER

Merck Private Company Profile

Jan 13, 2025EXHIBITPATENT OWNER

Johns Hopkins University Educational Institution Profile

Jan 13, 2025EXHIBITPATENT OWNER

Research and Faculty

Jan 13, 2025EXHIBITPATENT OWNER

Nobel Prize Winners

Jan 13, 2025EXHIBITPATENT OWNER

Is KEYTRUDA Right for You

Jan 13, 2025EXHIBITPATENT OWNER

Lorenzi_Epidemiology of Microsatellite Instability High

Jan 13, 2025EXHIBITPATENT OWNER

Boland_Microsatellite Instability

Jan 13, 2025EXHIBITPATENT OWNER

Siegel_Cancer statistics

Jan 13, 2025EXHIBITPATENT OWNER

Immune Checkpoint Inhibitors

Jan 13, 2025EXHIBITPATENT OWNER

How KEYTRUDA is Given

Jan 13, 2025EXHIBITPATENT OWNER

Accelerated Approval Letter

Jan 13, 2025EXHIBITPATENT OWNER

FDA Converts to Full Approval

Jan 13, 2025EXHIBITPATENT OWNER

Merck KEYTRUDA August 2024

Jan 13, 2025EXHIBITPATENT OWNER

Q2 2018 Earnings Call_July 27, 2018

Jan 13, 2025EXHIBITPATENT OWNER

Q3 2018 Earnings Call_October 25, 2018

Jan 13, 2025EXHIBITPATENT OWNER

Q4 2018 Earnings Call_February 01, 2019

Jan 13, 2025EXHIBITPATENT OWNER

Q1 2019 Earnings Call_April 30, 2019

Jan 13, 2025EXHIBITPATENT OWNER

List of Targeted Therapy Drugs

Jan 13, 2025EXHIBITPATENT OWNER

Q2 2018 Earnings Call_July 26, 2018

Jan 13, 2025EXHIBITPATENT OWNER

Q3 2018 Earnings Call_October 25, 2018

Jan 13, 2025EXHIBITPATENT OWNER

Q1 2019 Earnings Call_April 25, 2019

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 27, 2018

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 27, 2019

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 26, 2020

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 25, 2021

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 25, 2022

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 24, 2023

Jan 13, 2025EXHIBITPATENT OWNER

Cancer Statistics, 2017

Jan 13, 2025EXHIBITPATENT OWNER

Cancer Statistics, 2018

Jan 13, 2025EXHIBITPATENT OWNER

Cancer Statistics, 2019

Jan 13, 2025EXHIBITPATENT OWNER

Cancer Statistics, 2020

Jan 13, 2025EXHIBITPATENT OWNER

Cancer Statistics, 2021

Jan 13, 2025EXHIBITPATENT OWNER

Cancer Statistics, 2022

Jan 13, 2025EXHIBITPATENT OWNER

Cancer Statistics, 2023

Jan 13, 2025EXHIBITPATENT OWNER

Microsatellite Instability Biomarker

Jan 13, 2025EXHIBITPATENT OWNER

Merck Q2 2017 Earnings Call_July 28, 2017

Jan 13, 2025EXHIBITPATENT OWNER

Cancer-Related Direct-to-Consumer Advertising

Jan 13, 2025EXHIBITPATENT OWNER

Cost Information and Financial Help

Jan 13, 2025EXHIBITPATENT OWNER

Pricing Information for OPDIVO

Jan 13, 2025EXHIBITPATENT OWNER

Pricing Information for OPDIVO_YERVOY

Jan 13, 2025EXHIBITPATENT OWNER

Bristol Myers Squibb_YERVOY

Jan 13, 2025EXHIBITPATENT OWNER

Watt_Keytruda and Opdivo

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 26, 2016

Jan 13, 2025EXHIBITPATENT OWNER

SEC Form 10-K_February 28, 2017

Jan 13, 2025EXHIBITPATENT OWNER

Bristol-Myers Squibb 2017 SEC Form 10-K

Jan 13, 2025EXHIBITPATENT OWNER

Bristol-Myers Squibb 2018 SEC Form 10-K

Jan 13, 2025EXHIBITPATENT OWNER

Bristol-Myers Squibb 2019 SEC Form 10-K

Jan 13, 2025EXHIBITPATENT OWNER

Bristol-Myers Squibb 2020 SEC Form 10-K

Jan 13, 2025EXHIBITPATENT OWNER

Bristol-Myers Squibb 2021 SEC Form 10-K

Jan 13, 2025EXHIBITPATENT OWNER

Bristol-Myers Squibb 2022 SEC Form 10-K

Jan 13, 2025EXHIBITPATENT OWNER

Bristol-Myers Squibb 2023 SEC Form 10-K

Jan 13, 2025EXHIBITPATENT OWNER

Merck SEC Form 10-Q_March 31, 2018

Jan 13, 2025EXHIBITPATENT OWNER

Merck SEC Form 10-Q_March 31, 2023

Jan 13, 2025EXHIBITPATENT OWNER

Merck SEC Form 10-Q_June 30, 2023

Jan 13, 2025EXHIBITPATENT OWNER

Merck SEC Form 10-Q_September 30, 2023

Jan 13, 2025EXHIBITPATENT OWNER

Siegel_Cancer Statistics 2015

Jan 13, 2025EXHIBITPATENT OWNER

Noone_SEER Cancer Statistics Review

Jan 13, 2025EXHIBITPATENT OWNER

Canadian Cancer Society_Survival statistics for small intestine cancer

Jan 13, 2025EXHIBITPATENT OWNER

American Cancer Society_Survival rates for bile duct cancer

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Gastric Cancer

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_ Pancreatic Adenocarcinoma

Jan 13, 2025EXHIBITPATENT OWNER

NCCN _Hepatocellular Carcinoma

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Biliary Tract Cancers

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Small Bowel Adenocarcinoma

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Ampullary Adenocarcinoma

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Anal Carcinoma

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Prostate Cancer

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Uterine Neoplasms

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Ovarian Cancer

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Cervical Cancer

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Neuroendocrine and Adrenal Tumors

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Thyroid Carcinoma

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Breast Cancer

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Esophageal and Esophagogastric Junction Cancers

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Testicular Cancer

Jan 13, 2025EXHIBITPATENT OWNER

NCCN_Head and Neck Cancers

Jan 13, 2025EXHIBITPATENT OWNER

EXPUNGED

Jan 13, 2025EXHIBITPATENT OWNER

EXPUNGED

Jan 13, 2025EXHIBITPATENT OWNER

EXPUNGED

Jan 13, 2025EXHIBITPATENT OWNER

Lynch In Memoriam

Jan 13, 2025EXHIBITPATENT OWNER

Aaltonen_Replication errors

Jan 13, 2025EXHIBITPATENT OWNER

Aarnio_Cancer risk in mutation carriers

Jan 13, 2025EXHIBITPATENT OWNER

Chen_Small bowel adenocarcinoma

Jan 13, 2025EXHIBITPATENT OWNER

Review Designation Policy

Jan 13, 2025EXHIBITPATENT OWNER

Hsiehchen_Mutation burden

Jan 13, 2025EXHIBITPATENT OWNER

FDA grants accelerated approval

Jan 13, 2025EXHIBITPATENT OWNER

Prescription Drug Advertising

Jan 13, 2025EXHIBITPATENT OWNER

Jemperli U.S. Prescribing Information

Jan 13, 2025EXHIBITPATENT OWNER

Jemperli Prices_Coupons_Copay Cards

Jan 13, 2025EXHIBITPATENT OWNER

Support-Resources_Jemperli

Jan 13, 2025EXHIBITPATENT OWNER

GSK 2021 Annual Report

Jan 13, 2025EXHIBITPATENT OWNER

GSK 2022 Annual Report

Jan 13, 2025EXHIBITPATENT OWNER

GSK 2023 Annual Report

Jan 13, 2025EXHIBITPATENT OWNER

Yearly average currency exchange rates_IRS

Jan 13, 2025EXHIBITPATENT OWNER

Marked EX1001 Neugut Deposition

Jan 13, 2025EXHIBITPATENT OWNER

Marked EX1005 Neugut Deposition

Jan 13, 2025EXHIBITPATENT OWNER

Board Email regarding Motion to Seal

Jan 13, 2025EXHIBITPATENT OWNER

Confidential_Patent Owners Response

Jan 13, 2025PAPERPATENT OWNER

Confidential_Declaration of Brian J Segers

Jan 13, 2025EXHIBITPATENT OWNER

Deposition of Alfred I. Neugut_January 6, 2025

Jan 13, 2025EXHIBITPATENT OWNER

Patent Owners Motion to Seal

Jan 13, 2025PAPERPATENT OWNER

Patent Owners Updated Mandatory Notice

Jan 3, 2025PAPERPATENT OWNER

Notice of Deposition of Alfred I. Neugut

Jan 3, 2025PAPERPATENT OWNER

Petitioner's Updated Mandatory Notices

Dec 26, 2024PAPERPETITIONER

Notice of Intent to Designate Frank E. Scherkenback

Dec 26, 2024PAPERPATENT OWNER

Notice of Intent to Designate Corrin N. Drakulich

Dec 26, 2024PAPERPATENT OWNER

Notice of Intent to Designate Christina D. Brown-Marshall

Dec 26, 2024PAPERPATENT OWNER

Notice of Intent to Designate Casey M. Kraning

Dec 26, 2024PAPERPATENT OWNER

Notice of Intent to Designate Madelyn S. McCormick

Dec 26, 2024PAPERPATENT OWNER

Notice of Intent to Designate Sarah E. Jack

Dec 26, 2024PAPERPATENT OWNER

Patent Owner Power of Attorney

Dec 26, 2024PAPERPATENT OWNER

Declaration of Frank E. Scherkenbach

Dec 26, 2024EXHIBITPATENT OWNER

Declaration of Corrin N. Drakulich

Dec 26, 2024EXHIBITPATENT OWNER

Declaration of Christina D. Brown-Marshall

Dec 26, 2024EXHIBITPATENT OWNER

Declaration of Casey M. Kraning

Dec 26, 2024EXHIBITPATENT OWNER

Declaration of Madelyn S. McCormick

Dec 26, 2024EXHIBITPATENT OWNER

Declaration of Sarah E. Jack

Dec 26, 2024EXHIBITPATENT OWNER

Exhibit 3007

Dec 23, 2024EXHIBITBOARD

Notice of Stipulation to Modify Due Dates

Dec 12, 2024PAPERPATENT OWNER

Granting Petitioner’s Motions for Pro Hac Vice Admission of Jessica Stauring 37 C.F.R. § 42.10

Dec 10, 2024PAPERBOARD

Ex. 3006

Dec 9, 2024EXHIBITBOARD

ORDER Conduct of the Proceeding 37 C.F.R. § 42.5

Dec 9, 2024PAPERBOARD

Petitioner's Motion for Pro Hac Vice Admission of Jessica Stauring

Nov 25, 2024PAPERPETITIONER

Exhibit 1112

Nov 25, 2024EXHIBITPETITIONER

Amended Power of Attorney for Petitioner

Nov 25, 2024PAPERPETITIONER

Petitioner's Current List of Exhibits

Nov 25, 2024PAPERPETITIONER

Petitioner's Objections to Patent Owner's Exhibits

Oct 7, 2024PAPERPETITIONER

Patent Owner's Objections to Evidence

Oct 7, 2024PAPERPATENT OWNER

Institution Decision: Grant

Sep 23, 2024PAPERBOARD

Order: Scheduling Order

Sep 23, 2024PAPERBOARD

Patent Owner's Preliminary Sur-Reply

Jul 19, 2024PAPERPATENT OWNER

Petitioner's Reply to Patent Owner's Preliminary Response

Jul 12, 2024PAPERPETITIONER

Petitioner's Current List of Exhibits

Jul 12, 2024PAPERPETITIONER

Exhibit 1100

Jul 12, 2024EXHIBITPETITIONER

Exhibit 1101

Jul 12, 2024EXHIBITPETITIONER

ORDER – Request for Reply

Jul 8, 2024PAPERBOARD

Petitioner's Updated Mandatory Notices

Jul 1, 2024PAPERPETITIONER

Patent Owners Preliminary Response

Jun 26, 2024PAPERPATENT OWNER

Le_ASCO Presentation

Jun 26, 2024EXHIBITPATENT OWNER

FDA News Release

Jun 26, 2024EXHIBITPATENT OWNER

Kolata_Cancer Drug

Jun 26, 2024EXHIBITPATENT OWNER

McGinley_This is not the end

Jun 26, 2024EXHIBITPATENT OWNER

News Release_Merck

Jun 26, 2024EXHIBITPATENT OWNER

Signed IDS_975

Jun 26, 2024EXHIBITPATENT OWNER

Signed IDS_219

Jun 26, 2024EXHIBITPATENT OWNER

Signed IDS_187

Jun 26, 2024EXHIBITPATENT OWNER

Signed IDS_462

Jun 26, 2024EXHIBITPATENT OWNER

Signed IDS_287

Jun 26, 2024EXHIBITPATENT OWNER

Office Action_15/611,017

Jun 26, 2024EXHIBITPATENT OWNER

Reply to Action_15/611,017

Jun 26, 2024EXHIBITPATENT OWNER

Signed IDS_15/523,451

Jun 26, 2024EXHIBITPATENT OWNER

Sidney Kimmel Comprehensive Cancer Center

Jun 26, 2024EXHIBITPATENT OWNER

Initial Disclosure of Invalidity Contentions

Jun 26, 2024EXHIBITPATENT OWNER

Shaywitz_The Startling History

Jun 26, 2024EXHIBITPATENT OWNER

IPR2024‐00240_Paper No. 1

Jun 26, 2024EXHIBITPATENT OWNER

Claim Construction Order

Jun 26, 2024EXHIBITPATENT OWNER

Signed IDS_17/465,101

Jun 26, 2024EXHIBITPATENT OWNER

Maryland_Judicial Caseload Profile

Jun 26, 2024EXHIBITPATENT OWNER

Notice: Notice filing date accorded

Mar 26, 2024PAPERBOARD

Patent Owner's Mandatory Notice

Mar 22, 2024PAPERPATENT OWNER

Exhibit 1001

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1002

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1004

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1005

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1006

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1007

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1008

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1009

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1010

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1011

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1012

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1013

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1014

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1015

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1016

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1017

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1018

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1019

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1020 (Part 1 of 4)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1020 (Part 2 of 4)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1020 (Part 3 of 4)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1020 (Part 4 of 4)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1021

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 1 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 2 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 3 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 4 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 5 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 6 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 7 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 8 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 9 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 10 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1022 (Part 11 of 11)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1023

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1024

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1025

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1026

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1027

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1029

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1030

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1031

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1032

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1033

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1034

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1035

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1036

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1037

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1038

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1039

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1040

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1041

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1042

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1043

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1044

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1045

Mar 4, 2024EXHIBITPETITIONER

1046

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1047

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1048

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1049

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1050

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1051

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1053

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1054

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1055

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1057

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1058

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1063

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1064

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1065

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1066

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1067

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1068

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1069

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1070

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1071

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1072

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1073

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1074

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1075

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1076

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1077

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1078

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1079

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1080

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1081

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1082

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1083

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1084

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1085

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1086

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1087

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1088

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1089 (Part 1 of 2)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1089 (Part 2 of 2)

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1090

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1092

Mar 4, 2024EXHIBITPETITIONER

Exhibit 1093

Mar 4, 2024EXHIBITPETITIONER

Petition for Inter Partes Review of U.S. Patent No. 11,325,974

Mar 4, 2024PAPERPETITIONER

Power of Attorney for Petitioner

Mar 4, 2024PAPERPETITIONER

Exhibit 1003

Mar 4, 2024EXHIBITPETITIONER