The detailed information for PTAB case with proceeding number IPR2024-00649 filed by Merck Sharp & Dohme LLC et al. against The Johns Hopkins University on Mar 13, 2024. This includes filing dates, application numbers, tech centers, patent numbers, and current case status.
The table below shows documents filed in the case, listing each document name, filing date, document type, and filing party. Tracking these filings indicates the activity of the parties involved in the case, and the types of documents filed can provide insights into the legal strategies being employed.
| Document Name | Filing Date | Category | Filing Party |
|---|---|---|---|
Alert me when new update on this case | |||
Public_Patent Owners Sur-Reply | Jun 17, 2025 | PAPER | PATENT OWNER |
Public_Deposition Transcript of Paul E. Oberstein | Jun 17, 2025 | EXHIBIT | PATENT OWNER |
Ex. 3009 Attorney Correspondence | Jun 16, 2025 | EXHIBIT | BOARD |
Order: Canceling Oral Argument | Jun 16, 2025 | PAPER | BOARD |
ORDER Setting Oral Argument 37 C.F.R. § 42.70 | Jun 3, 2025 | PAPER | BOARD |
Confidential_Patent Owners Sur-Reply | Jun 3, 2025 | PAPER | PATENT OWNER |
Confidential_Deposition Transcript of Paul E. Oberstein | Jun 3, 2025 | EXHIBIT | PATENT OWNER |
Patent Owners Motion to Seal Sur-Reply and Exhibits | Jun 3, 2025 | PAPER | PATENT OWNER |
Petitioner Reply [Redacted] | May 20, 2025 | PAPER | PETITIONER |
Exhibit 1137 [Redacted] | May 20, 2025 | EXHIBIT | PETITIONER |
Exhibit 1150 [Redacted] | May 20, 2025 | EXHIBIT | PETITIONER |
Exhibit 1244 [Redacted] | May 20, 2025 | EXHIBIT | PETITIONER |
Exhibit 1245 [Redacted] | May 20, 2025 | EXHIBIT | PETITIONER |
Exhibit 1283 [Redacted] | May 20, 2025 | EXHIBIT | PETITIONER |
Petitioner's Request for Oral Argument | May 16, 2025 | PAPER | PETITIONER |
Patent Owner's Request for Oral Argument | May 16, 2025 | PAPER | PATENT OWNER |
Petitioner's Current List of Exhibits | May 6, 2025 | PAPER | PETITIONER |
Exhibit 1113 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1114 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1115 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1117 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1120 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1122 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1128 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1129 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1130 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1134 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1135 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1136 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1138 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1139 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1140 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1141 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1145 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1146 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1147 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1148 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1149 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1242 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1243 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1246 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1279 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1280 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1281 | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1282 | May 6, 2025 | EXHIBIT | PETITIONER |
Petitioner's Motion to Seal | May 6, 2025 | PAPER | PETITIONER |
Exhibit 1116 [Confidential] | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1118 [Confidential] | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1119 [Confidential] | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1150 [Confidential] | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1245 [Confidential] | May 6, 2025 | EXHIBIT | PETITIONER |
Exhibit 1283 [Confidential] | May 6, 2025 | EXHIBIT | PETITIONER |
Petitioner's Reply | May 6, 2025 | PAPER | PETITIONER |
Email from the panel regarding expunging paper 36 | Apr 10, 2025 | EXHIBIT | BOARD |
Notice of Stipulation to Modify Due Dates | Apr 10, 2025 | PAPER | PETITIONER |
Petitioner's Notice of Deposition of Dung Le M.D | Apr 10, 2025 | PAPER | PETITIONER |
Petitioner's Notice of Deposition of Nils Lonberg, Ph.D. | Apr 10, 2025 | PAPER | PETITIONER |
Petitioner's Notice of Deposition of Jennifer Newberger | Apr 8, 2025 | PAPER | PETITIONER |
Petitioner's Notice of Deposition of Richard Goldberg, M.D. | Apr 8, 2025 | PAPER | PETITIONER |
EXPUNGED | Apr 8, 2025 | PAPER | PETITIONER |
Patent Owners Updated Mandatory Notice | Mar 28, 2025 | PAPER | PATENT OWNER |
Patent Owners Updated Power of Attorney | Mar 28, 2025 | PAPER | PATENT OWNER |
ORDER Conditionally Granting Patent Owner’s Motions for Pro Hac Vice Admission of Caroline (Gracie) Koonce. 37 C.F.R. § 42.10 | Mar 26, 2025 | PAPER | BOARD |
Patent Owner's Unopposed Motion for PHV Admission of Caroline Koonce | Mar 18, 2025 | PAPER | PATENT OWNER |
PHV Declaration - Caroline Koonce | Mar 18, 2025 | EXHIBIT | PATENT OWNER |
Public_Patent Owner's Response | Feb 6, 2025 | PAPER | PATENT OWNER |
Petitioner's Objections to Patent Owner's Exhibits | Jan 30, 2025 | PAPER | PETITIONER |
Patent Owners Updated Mandatory Notice | Jan 29, 2025 | PAPER | PATENT OWNER |
Curriculum Vitae of Dr. Nils Lonberg | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Dung_ASCO Annual Meeting | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
FDA News Release | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Kolata_Cancer Drug Proves to Be Effective Against Multiple Tumors | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
McGinley_This is not the end | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
News Release_Keytruda | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
News Release_Merck Financial | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Bacher_Development of a Fluorescent Multiplex Assay | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Diaz_Liquid Biopsies | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Brahmer_Phase I Study | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
The Cancer Genome Atlas Network | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Mandrekar_All-Comers versus Enrichment Design | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Freidlin_Randomized Clinical Trials | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Malik_Consensus Report | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NIH_What is Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Weiss_Open Questions | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Mumphrey_Distinct Mutational Processes | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Jenkins_Antigen Presentation | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Wherry_Viral Persistence | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Lotze_Lysis of Fresh and Cultured Autologous Tumor | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Briukhovetska_Interleukins in Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Bod_B-Cell-Specific Checkpoint | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Wang_CD19 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Michaud_Regulatory B Cells in Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Nakhoda_Addressing Recent Failures | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Korman_The Foundations | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NIH_Immune Checkpoint Inhibitors | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Boland_Microsatellite Instability | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Branch_Immune Surveillance | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Kloor_Immune Evasion | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Zhong_Comparison of Molecular and Cellular Phenotypes | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Thomas_Advancing Translational Research | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Lacombe_The Dream and Reality | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Shaywitz_The Startling History | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
FDA Approves Mercks KEYTRUDA (pembrolizumab) | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
First-Study-Evaluating-DNA-Mismatch-Repair | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck-Receives-Breakthrough-Therapy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
MRK-USQ_Transcript_2019-02-01-Final | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck-Financial-Results-2023 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck-Financial-Results-2022 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck-Financial-Results-2021 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck-Financial-Results-2020 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck-Financial-Results-2019 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Exhibit 20 to JHU Corrected Answer and Counterclaims | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
statistic_id973523_top-drugs-based-on-projected-2024-global-sales | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
1-22-cv-03059-100, Ltr fr JHU to Judge Aslan | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Connolly_Novel Mouse Models | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Sun_Immune checkpoint therapy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Dobosz_Challenges of the Immunotherapy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Gardner_Merck suffers bad week | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Liu_Merck's Keytruda flunks pivotal studies | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Hopkins_Merck Keeps Striking Out | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck's trial of Keytruda | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Study of Pembrolizumab | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
van der Bruggen_A gene encoding an antigen | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Lawrence_Mutational heterogeneity | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Kitano_Myeloid-derived suppressor | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Snyder_Genetic basis for clinical response | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Chan_Genetic Basis for Clinical Response | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
McGranahan_Clonal neoantigens | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Hellmann_Tumor Mutational | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
FDA grants nivolumab accelerated approval | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Boyiadzis_Significance and implications | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Declaration of Dr. Richard Goldberg | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Bray_Global cancer statistics | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Zeineddine_Survival improvement | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Patel_The rising tide | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Sinicrope_Increasing Incidence | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Sinicrope_Lynch Syndrome | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Sargent_Defective mismatch repair | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Keung_The eighth edition American Joint Committee | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Ogunwobi_Biomarkers in Colorectal Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Kong_Prolonged surveillance | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Modulation of fluorouracil | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Dy_Long-term survivors | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Saltz_Irinotecan plus fluorouracil | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Sanoff_Five-year data | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Hurwitz_Bevacizumab plus irinotecan | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Saltz_Phase II trial | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Van Cutsem_Cetuximab and chemotherapy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Van Cutsem_Open-label phase III trial | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Tabernero_Aflibercept versus placebo | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Venook_Effect of First-Line Chemotherapy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Lucas_A decade of advances | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Modest_Treatment sequencing | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Grothey_Regorafenib monotherapy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Mayer_Randomized trial of TAS-102 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
McRee_Optimal management | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Robert_Pembrolizumab versus Ipilimumab | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Reck_Pembrolizumab versus Chemotherapy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Le_Mismatch repair deficiency | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Ethical Guidelines | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
The Belmont Report | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
The Cancer Letter, Vol. 43, No. 38, Oct. 13, 2017 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
The Cancer Letter, Vol. 48, No. 23, June 10, 2022 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
How Beth Carner went from six weeks | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck KEYTRUDA May 23, 2017 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck KEYTRUDA Oct. 2015 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck KEYTRUDA Aug. 2016 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck KEYTRUDA Mar. 2017 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck KEYTRUDA May 18, 2017 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck KEYTRUDA June 2020 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Declaration of Dung Le, M.D. | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Investigator Initiated Clinical Trial Research | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
O'Neil_Safety and antitumor activity | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
FDA Grants Priority Review | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Merck Makes 3 Million Charitable Donation | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
ASCO 2015_Mismatch Repair Deficiency | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Video interview | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Declaration of Ms. Jennifer Newberger | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Dickersin_Report from the panel | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Moher_Clinical-trial registration | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
International Clinical Trials | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
The Food and Drug Administration Modernization Act | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Laine_Update on Trials Registration | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Food and Drug Administration Amendments Act | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
About ClinicalTrials.gov_Nat'l Library of Medicine | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
7th Revision of the Declaration of Helsinki | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
42 C.F.R. Pt. 11_2024 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
42 USC 282(j) Paragraph 21 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Protocol Registration Data | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
21 U.S.C. 331 - Prohibited acts | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
21 U.S.C. 333 - Penalties | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
De Angelis_Clinical trial registration | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Response_The American Heritage dictionary | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Response_Collins Dictionary | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Response_Oxford Dictionary | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Response_The Chambers Dictionary | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Response_Merriam-Webster's | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Response_Cambridge Advanced Learner's | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Response_Webster's Third New International | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Opening Brief Regarding Claim Construction | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Opening Claim Construction Brief | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Responsive Brief Regarding Claim Construction | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Stenographic Deposition of Alfred I. Neugut, M.D., Ph.D., | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Record History Tab | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Comparison_ClinicalTrials.gov | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 1 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 2 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 4 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 5 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 6 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 7 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 8 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 9 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Andre_KEYNOTE-177 Investigators | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Henig_Could Immunotherapy Lead the Way | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Exhibit 7 KEYTRUDA claim chart | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Marques_Tumor mutational burden | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Le_Phase II Open-label study | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Nair_High Impact Journals 2024 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 3 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Document 10 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Email correspondence from Luis Diaz | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Breakthroughs in Immunotherapy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Guidance for Industry | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Email correspondence from Preston K. Ratliff | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Accelerated Approval Letter | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Siegel_Cancer Statistics 2015 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Noone_SEER Cancer Statistics Review | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Canadian Cancer Society_Survival statistics for small intestine cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
American Cancer Society_Survival rates for bile duct cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Gastric Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_ Pancreatic Adenocarcinoma | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN _Hepatocellular Carcinoma | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Biliary Tract Cancers | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Small Bowel Adenocarcinoma | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Ampullary Adenocarcinoma | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Anal Carcinoma | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Prostate Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Uterine Neoplasms | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Ovarian Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Cervical Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Neuroendocrine and Adrenal Tumors | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Thyroid Carcinoma | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Breast Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Esophageal and Esophagogastric Junction Cancers | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Testicular Cancer | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
NCCN_Head and Neck Cancers | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential– Protective Order Material | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential– Protective Order Material | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential– Protective Order Material | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Lynch In Memoriam | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Aarnio_Cancer risk in mutation carriers | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Chen_Small bowel adenocarcinoma | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Review Designation Policy | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Hsiehchen_Mutation burden | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Deposition of Alfred I. Neugut_January 6, 2025 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Keytruda_ Full Prescribing Information | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
U.S. Patent No. 11,591,393 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Excerpts from Prosecution History of U.S. Patent No. 11,591,393 | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Bonneville_Landscape of Microsatellite | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Akagi_Real-world data | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
FDA Approves Mercks Keytruda for Patients With MSI‑H/dMMR | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Marked EX1001 Neugut Deposition | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Marked EX1005 Neugut Deposition | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Board Email regarding Motion to Seal | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Confidential_Patent Owner's Response | Jan 23, 2025 | PAPER | PATENT OWNER |
Aaltonen_Replication errors | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Declaration of Dr. Nils Lonberg | Jan 23, 2025 | EXHIBIT | PATENT OWNER |
Patent Owners Motion to Seal | Jan 23, 2025 | PAPER | PATENT OWNER |
Patent Owners Updated Mandatory Notice | Jan 3, 2025 | PAPER | PATENT OWNER |
Notice of Deposition of Alfred I. Neugut | Jan 3, 2025 | PAPER | PATENT OWNER |
Petitioner's Updated Mandatory Notices | Dec 26, 2024 | PAPER | PETITIONER |
Notice of Intent to Designate Frank E. Scherkenback | Dec 26, 2024 | PAPER | PATENT OWNER |
Notice of Intent to Designate Corrin N. Drakulich | Dec 26, 2024 | PAPER | PATENT OWNER |
Notice of Intent to Designate Christina D. Brown-Marshall | Dec 26, 2024 | PAPER | PATENT OWNER |
Notice of Intent to Designate Casey M. Kraning | Dec 26, 2024 | PAPER | PATENT OWNER |
Notice of Intent to Designate Madelyn S. McCormick | Dec 26, 2024 | PAPER | PATENT OWNER |
Notice of Intent to Designate Sarah E. Jack | Dec 26, 2024 | PAPER | PATENT OWNER |
Patent Owner Power of Attorney | Dec 26, 2024 | PAPER | PATENT OWNER |
Declaration of Frank E. Scherkenbach | Dec 26, 2024 | EXHIBIT | PATENT OWNER |
Declaration of Corrin N. Drakulich | Dec 26, 2024 | EXHIBIT | PATENT OWNER |
Declaration of Christina D. Brown-Marshall | Dec 26, 2024 | EXHIBIT | PATENT OWNER |
Declaration of Casey M. Kraning | Dec 26, 2024 | EXHIBIT | PATENT OWNER |
Declaration of Madelyn S. McCormick | Dec 26, 2024 | EXHIBIT | PATENT OWNER |
Declaration of Sarah E. Jack | Dec 26, 2024 | EXHIBIT | PATENT OWNER |
Exhibit 3007 | Dec 23, 2024 | EXHIBIT | BOARD |
Notice of Stipulation to Modify Due Dates | Dec 12, 2024 | PAPER | PATENT OWNER |
Granting Petitioner’s Motions for Pro Hac Vice Admission of Jessica Stauring 37 C.F.R. § 42.10 | Dec 10, 2024 | PAPER | BOARD |
Ex. 3006 | Dec 9, 2024 | EXHIBIT | BOARD |
ORDER Conduct of the Proceeding 37 C.F.R. § 42.5 | Dec 9, 2024 | PAPER | BOARD |
Petitioner's Motion for Pro Hac Vice Admission of Jessica Stauring | Nov 25, 2024 | PAPER | PETITIONER |
Exhibit 1112 | Nov 25, 2024 | EXHIBIT | PETITIONER |
Amended Power of Attorney for Petitioner | Nov 25, 2024 | PAPER | PETITIONER |
Petitioner's Current List of Exhibits | Nov 25, 2024 | PAPER | PETITIONER |
Patent Owners Objections to Evidence | Oct 11, 2024 | PAPER | PATENT OWNER |
Institution Decision: Grant | Sep 27, 2024 | PAPER | BOARD |
Order: Scheduling Order | Sep 27, 2024 | PAPER | BOARD |
Exhibit 1008 | Sep 10, 2024 | EXHIBIT | PETITIONER |
Petitioner's Updated Mandatory Notices | Jul 1, 2024 | PAPER | PETITIONER |
Notice filing date accorded to petition | Apr 15, 2024 | PAPER | BOARD |
Patent Owner's Mandatory Notice | Apr 1, 2024 | PAPER | PATENT OWNER |
Exhibit 1001 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1002 (Part 1 of 2) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1002 (Part 2 of 2) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1004 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1005 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1006 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1007 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1009 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1010 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1011 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1012 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1013 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1014 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1015 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1016 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1017 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1018 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1019 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1020 (Part 1 of 4) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1020 (Part 2 of 4) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1020 (Part 3 of 4) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1020 (Part 4 of 4) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1021 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 1 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 2 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 3 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 4 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 5 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 6 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 7 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 8 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 9 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 10 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1022 (Part 11 of 11) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1023 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1024 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1025 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1026 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1027 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1029 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1030 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1031 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1032 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1033 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1034 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1035 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1036 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1037 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1038 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1039 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1040 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1041 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1042 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1043 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1044 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1045 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1046 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1047 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1048 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1049 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1050 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1051 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1053 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1054 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1055 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1057 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1058 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1063 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1064 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1065 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1066 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1067 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1068 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1069 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1070 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1071 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1072 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1073 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1074 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1075 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1076 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1077 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1078 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1079 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1080 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1081 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1082 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1083 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1084 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1085 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1086 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1087 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1088 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1089 (Part 1 of 2) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1089 (Part 2 of 2) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1090 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1091 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1092 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1093 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1094 (Part 1 of 2) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1094 (Part 2 of 2) | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1095 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1096 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Exhibit 1003 | Mar 13, 2024 | EXHIBIT | PETITIONER |
Petition for Inter Partes Review of U.S. Patent No. 11,629,187 | Mar 13, 2024 | PAPER | PETITIONER |
Power of Attorney for Petitioner | Mar 13, 2024 | PAPER | PETITIONER |