Patent Owner's Preliminary Response | Sep 22, 2025 | PAPER | PATENT OWNER |
EX-1044-Quanterix 15269142 Prosecution History pt. 1 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1044-Quanterix 15269142 Prosecution History pt. 2 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1044-Quanterix 15269142 Prosecution History pt. 3 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 1 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 2 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 3 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 4 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 5 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 6 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 7 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 8 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 9 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 10 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 11 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 12 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 13 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 14 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 15 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 16 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 17 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 18 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 19 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1045-Quanterix 14111326 Prosecution History pt. 20 | Sep 19, 2025 | EXHIBIT | PETITIONER |
EX-1046-FDA Clears First Blood Test Used in Diagnosing Alzheimer’s Disease | Sep 19, 2025 | EXHIBIT | PETITIONER |
Opposition to Q 2mo Discretionary Denial Request | Sep 19, 2025 | PAPER | PETITIONER |
Patent Owner's Updated Mandatory Notice re Lead and Backup Counsel | Aug 20, 2025 | PAPER | PATENT OWNER |
Patent Owner's Exhibit List | Aug 20, 2025 | PAPER | PATENT OWNER |
US Patent Application No. 15/269,142 Office Action Rejection dated January 29, 2015 | Aug 20, 2025 | EXHIBIT | PATENT OWNER |
US Patent Application No. 15/269,142 Office Action Rejection dated December 31, 2018 | Aug 20, 2025 | EXHIBIT | PATENT OWNER |
Patent Owner's Brief in Support of Discretionary Denial | Aug 20, 2025 | PAPER | PATENT OWNER |
Patent Owner's Updated Power of Attorney | Aug 20, 2025 | PAPER | PATENT OWNER |
Petitioner's Updated Mandatory Notice | Jul 1, 2025 | PAPER | PETITIONER |
Notice: Notice filing date accorded | Jun 20, 2025 | PAPER | BOARD |
Notice: Mandatory Notice | Jun 16, 2025 | PAPER | PATENT OWNER |
Notice: Power of Attorney | Jun 16, 2025 | PAPER | PATENT OWNER |
EX-1001 U.S. Patent No. 11,275,092 (“the ’092 Patent”) | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1004 Curriculum vitae of Petitioner’s Expert John Todd, PhD | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1005 Single-molecule enzyme-linked immunosorbent assay detects serum pro | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1006 How Low Can You Go? | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1007 Diagnostic Method For Alzheimer’s Disease By Screening For Tau-Pept | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1008 File History of US application No. 08/159,969 | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1009 Digital Concentration Readout of Single Enzyme Molecules Using Femt | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1010 Simultaneous Detection of Single Molecules and Singulated Ensembles | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1011 Next-Generation Diagnostics A startup can detect tiny traces | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1012 Ultrasensitive Flow-based Immunoassays Using Single-Molecule | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1013 Nanoparticle-Based Bio-Bar Codes for the Ultrasensitive | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1014 Nanoparticle-based bio-barcode assay redefines | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1015 Duffy et al., US2010/0075407 | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1016 Digital Readout of Target Binding with Attomole | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1017 Neuron-specific enolase and tau protein as neurobiochemical markers | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1018 Assessment of the Cerebral Ischemic/Reperfusion Injury | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1019 Ding et al., Transl Neurodegener | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1020 The Role of Tau in Alzheimer’s Disease and Related Disorders | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1021 A protein factor essential for microtubule assembly | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1002 Select portions of prosecution history of the ’092 Patent Pt. 1 | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1002 Select portions of prosecution history of the ’092 Patent Pt. 2 | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1023 Konzack et a., “Swimming against the Tide: Mobility of the | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1024 INNOTEST hTAU Ag | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1025 Biomarkers for Alzheimer’s disease – Clinical needs and application | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1026 Detection of τ Proteins in Normal and Alzheimer’s Disease | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1027 Tau as a Marker for Early CNS Damage | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1028 Monoclonal Antibodies Directed Against the Microtubule-Associated | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1029 Current state and future directions of neurochemical biomarkers | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1031 Tau as a biomarker of neurodegenerative diseases | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1032 CSF markers for incipient Alzheimer’s disease | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1033 Quanterix Single Molecule Arrays for Digital Detection in Complex | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1034 simoa Assay Kits | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1035 Single-Molecule Detection for Femtomolar Quantification of Proteins | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1036 Singulex | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1037 Mild traumatic brain injury: a risk factor for neurodegeneration | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1038 Head trauma as a risk factor for Alzheimer’s disease | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1039 Quanterix Announces Commercial Availability of its Simoa Single | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1040 Quanterix Issued Key Patent for Simoa™ Technology | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1041 Quanterix Announces Key Patents Issued for Simoa Platform | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1042 Increases of Plasma Levels of Glial Fibrillary Acidic Protein, Tau | May 28, 2025 | EXHIBIT | PETITIONER |
Notice: Power of Attorney | May 28, 2025 | PAPER | PETITIONER |
EX-1043 Declaration of Ingrid | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1043 Declaration of Ingrid Pt. 2 | May 28, 2025 | EXHIBIT | PETITIONER |
EX-1003 Expert Declaration | May 28, 2025 | EXHIBIT | PETITIONER |
Petition: as filed | May 28, 2025 | PAPER | PETITIONER |
EX-1030 Alzheimer's Disease | May 28, 2025 | EXHIBIT | PETITIONER |